News on measuring and increasing the impact of research. Covers research-impact data, AI publishing workflows, open-access programs, and scholarly metrics.
A Kessler Foundation researcher will examine the impact of social determinants on brain health and MS outcomes in Latinos. The study aims to improve healthcare access and quality for this minoritized group.
A nationwide cohort study found that COVID-19 survivors exhibit lower all-cause mortality and congestive heart failure but higher acute myocarditis and deep vein thrombosis risks. Younger, non-vaccinated patients with preexisting cardiovascular risk factors face elevated cardiovascular complications.
A recent study from the University of Georgia found that over 70% of respondents with chronic pain would alter their daily plans based on weather-based pain forecasts. The study suggests that developing a reliable pain-based weather forecast could help individuals take preventative measures to manage their pain levels.
Researchers at Kennedy Krieger and Boston Children's Hospital have discovered a new way to decrease early seizure likelihood among infants with Sturge-Weber Syndrome. Presymptomatic treatment involving anti-seizure medication and low-dose aspirin improves neurologic outcomes.
Researchers found that reducing stimulant use was associated with significant improvement in measures of health and recovery among people with stimulant use disorder. This suggests that a more nuanced perspective on measuring treatment success may be beneficial.
Dr. Deneen's research has revealed that astrocytes communicate with neurons, influencing brain circuits and animal behavior, potentially leading to new treatments for neurological disorders. His work could provide valuable insights into developmental neurobiology and brain diseases.
Research found a significant increase in cardiovascular disease deaths related to substance use, particularly among young adults and certain racial and ethnic groups. The study highlights the need for comprehensive public health efforts to address substance use and its impact on heart health.
Researchers discuss clonal hematopoiesis, a condition where cells harbor somatic mutations, and its association with aging, solid tumors, and treatment outcomes. Emerging evidence suggests that CH may play a role in cancer development and survival.
Researchers investigate grain size and temperature effects on Ti deformation at extremely low temperatures, finding that cryogenic temperatures trigger deformation twinning, boosting strength and ductility. The study proposes a modified Hall-Petch relationship to explain strengthening mechanisms at cryogenic temperatures.
Researchers unveiled a previously unknown effect of PG545 in ovarian cancer cells, inducing DNA damage and promoting autophagic degradation of RAD51. This breakthrough could aid in selecting the most appropriate treatments for ovarian cancer patients with PARPi resistance.
Researchers have developed a thermal management technique for photonic packages using glass substrates and thermoelectric vias, enabling precise temperature control. The technology, termed SimTEC, combines through glass vias partially filled with copper and thermoelectric materials to reduce thermal resistance between chips.
Researchers found a shared genetic trait that predicts a higher risk of small lung vessel disease and its severe form, pulmonary arterial hypertension. This discovery could lead to personalized treatments for patients with limited oxygen response.
Researchers from Binghamton University are unraveling the workings of Group B Strep (GBS) infections, which could someday lead to a vaccine. They have identified a novel protein that could serve as a vaccine candidate to fight this bacterium, impacting women's reproductive health and neonatal outcomes.
Mobile methadone units show significant impact in expanding opioid treatment access in rural areas, with a 13-point increase in Medication for Opioid Use Disorder (MOUD) treatment rates. Adding units exclusively to rural Louisiana provides nearly 20% of beneficiaries within 24 miles of a provider.
Researchers at the University of Cincinnati are testing a new tongue exercise approach to improve swallowing function in stroke patients. The trial aims to provide concrete evidence-based recommendations for treating dysphagia, a common post-stroke complication that can have significant impacts on patients' health and quality of life.
A new study reveals that Respiratory Syncytial Virus (RSV) can infect nerve cells, trigger inflammation, and cause nerve damage. RSV was previously thought to only infect the respiratory tract, but this finding suggests a potential link between the virus and neurological symptoms in children.
Researchers found that people with noncommunicable diseases experienced greater psychological distress, increased alcohol consumption, and disrupted medical care. Those with NCDs were more likely to report anxiety, depression, and difficulty accessing non-COVID medical care.
A recent study published in Aging Cell found a balance between naïve and memory immune cells accelerates or slows down biological aging. The team discovered using novel tools for immune profiling, which opened new doors to understanding the relationships between the immune system and biological age.
A study of nearly 900 patients found that delayed or missed diagnoses contributed to temporary or permanent harm in three-quarters of cases. Improving diagnostic tools and techniques could reduce errors by up to 40%, according to researchers.
A Lancaster University-led study found improvements in mental health and reductions in burglaries among residents involved in the Big Local community empowerment initiative. However, benefits were unequally distributed, with men and those with higher education reporting better outcomes.
A study redevelops a framework for teaching artificial intelligence and robotics to preschool children, providing five big ideas that can be grasped by young kids. The framework aims to prepare children to understand and use AI tools effectively, promoting healthy and responsible learning in the rapidly developing digital society.
A Cochrane review found that e-cigarettes lead to better chances of quitting smoking than patches, gums, lozenges, or other traditional NRT. Eight to 10 out of 100 people using nicotine e-cigarettes quit compared to six out of 100 using traditional NRT.
Cancer immunotherapy can cause severe colitis due to hyper-activated immune T cells and deleted regulatory T cells. Researchers at Michigan Medicine have identified a new mouse model that develops colitis after treatment with antibodies used for tumor immunotherapy, revealing the mechanism behind this side effect.
Research from Drexel University finds that customers are more likely to remain loyal to a grocery store when using regular checkout service. The perceived ease of checkout, sense of entitlement, and number of items purchased play a role in explaining the effect of loyalty.
The UC San Diego Center for Learning Health Systems Science will provide training for clinicians and researchers in the emerging field of learning health systems science. The center aims to improve patient outcomes, enhance healthcare efficiency, and increase diversity in the workforce.
A study by Chung-Ang University found that electronic voting enhances shareholders' perception of corporate governance, increasing the market value of a firm's cash holdings. Firms with larger free cash flows and minority ownership saw stronger governance effects from adopting electronic voting.
The MU Extension program has proven results, showing improvements in physical energy, self-confidence, and muscle strength among participants. The program also reduces the risk of falling and provides social enjoyment for participants, who often form close relationships with instructors and each other.
Cancer stem cell-derived exosomes (CSC-Exos) are essential for communication between CSCs and other cells in the tumor microenvironment, contributing to cancer progression. The editorial highlights their potential as a novel clinical tool for diagnosis, prognosis, prevention of tumor recurrence, and therapeutic strategy
A major research study argues that diversifying away from maize and switching to crops like cassava, millet, and sorghum will improve nutrition security in sub-Saharan Africa. The study highlights the need for policymakers to prioritize nutritional quality in agricultural policy.
Researchers found that higher levels of omega-3 fatty acids in the blood plasma were associated with better lung function and longer survival without needing a lung transplant. This was consistent regardless of smoking history or cardiovascular disease.
A Cornell University-led research finds that social media platforms and the metrics that reward content creators for revealing their innermost selves open them to identity-based harassment. Influencers use platform filtering systems and other strategies to manage vulnerabilities, but the authors caution that internet hate and harassmen...
Researchers examine the dynamic nature of fear responses in varied environments, shedding light on physical manifestation of memory in the brain. The study reveals that fear memories are linked to pathological states like PTSD and generalized anxiety, with direct translational relevance for disorders involving dysregulated fear responses.
A new method for desalinating seawater using hydrate-based desalination technology has been developed, offering a low-energy solution for producing freshwater. The research team calculated optimal temperatures for enhanced efficiency, with maximum water yields reaching up to 67% in certain brine concentrations.
GFH009 inhibits tumor growth and induces apoptosis in various HHM-derived cell lines. The compound's mechanism of action involves rapid 'on-off' inhibition of CDK9, which exerts a proapoptotic effect on cancer cells.
New analysis by NREL researchers estimates that 56% of paper and cardboard waste is landfilled, contributing to energy and resource losses. The study highlights opportunities for diversion and recovery of technical and economic value from these materials.
A recent study published in Cerebral Cortex found that participants exposed to 18-Hz beta binaural beats had significantly higher accuracy and faster response times during comprehension tasks. This suggests that binaural beat stimulation at this frequency may be a potential tool for improving language skills.
A new tool, CellHint, has been developed to unify different single-cell data, creating harmonized datasets. Researchers applied CellHint to reveal underexplored connections between healthy and diseased lung cell states and identified potential interests for future research in adult human hippocampus.
Binghamton University will receive $6 million from the NSF to translate cutting-edge research into real-world applications and promote regional entrepreneurship. The initiative aims to increase the university's capacity for translational research, providing students with practical training and career development opportunities.
Researchers from Brazil discuss the management of refractory or relapsed classic Hodgkin lymphoma in adults, highlighting novel agents such as brentuximab vedotin and immunotherapy. The Brazilian healthcare system's constraints are also considered when making treatment decisions.
Hyperemesis gravidarum is a debilitating condition causing intense vomiting, hair loss, and mental health issues. Researcher Cheryl Beck studied 33 blog posts from women in Australia, finding six consistent themes: physical debilitation, emotional distress, and financial struggles.
A new study by the University of Plymouth shows that at-risk individuals are more likely to engage with loot boxes than those without, highlighting the need for stricter enforcement around these features. The research found that loot box use is driven by beliefs such as 'I'll win in a minute', echoing the psychology seen in gambling.
The study identifies FAM53C as a cytosolic-anchoring inhibitory binding protein of the kinase DYRK1A, regulating its activity and cellular location. This finding may provide potential clinical insights into treating Down syndrome and related diseases.
Research finds that animated short videos are an effective means for disseminating environmental health information to health professionals. The studies showed significant increases in participant knowledge and perceived comfort in identifying at-risk patients impacted by air pollution.
Researchers found that less than two percent of patients in Medicaid and commercially insured plans received Z-codes to document Social Determinants of Health. The study highlights the need for improved tracking and documentation of SDOH in healthcare settings, with recommendations for policy changes and provider education.
Researchers found that colon cancer screenings reduce cancer rates by about 0.5 percent, doubling previous estimates of a quarter of a percentage point. This effect is twice the impact of just being invited to screen, suggesting that actual screening rather than just the offer makes a difference.
Researchers revisited melatonin's effects on cancer in mice, finding that nighttime administration inhibits chemically induced mammary tumor development. The study highlights the importance of timing in using this freely available compound for cancer prevention and treatment.
A recent study published in PLOS ONE found that countries with more comprehensive welfare systems experience lower levels of technostress, which is caused by technological change. This suggests that state support can mitigate the negative effects of digitalization on health and social inequality.
Researchers identified key proteins involved in the process, including mTOR and TSC2, which can be targeted to slow or halt disease progression. The study's findings suggest new therapeutic strategies to save dopaminergic neurons and alleviate motor and cognitive symptoms.
A study by the University of Sydney and University of Warwick found large gaps in evidence regarding opioid medicines for cancer pain. Non-opioid medicines, including aspirin, may be as effective as opioids for background cancer pain.
Researchers identified Elovanoid-34, a molecule that modulates the activity of TXNRD1 protein, which regulates antioxidant defenses. This discovery opens new therapeutic avenues for degenerative brain and eye diseases, as well as promoting healthy aging.
Researchers found that ponderosa pine trees suffer from warming, contradicting the space-for-time substitution method. Climate change is happening faster than trees can adapt, putting them at risk of extinction.
A study published in Environmental Health Perspectives found that exposure to phthalates can lower the odds of getting pregnant, but not lead to pregnancy loss. The researchers also discovered associations between preconception phthalate exposure and changes in women's reproductive hormones, inflammation, and oxidative stress.
A NSF-funded project, MABLE, is developing a digital app using crowdsensing, AI, and robotics to empower individuals with responsive maps and turn-by-turn instructions. The app aims to improve accessibility and navigation for persons with visual or mobility impairments, such as those with low vision and wheelchair users.
Researchers identify Caribbean Islands as prone to rapid drought conditions known as flash droughts. A new drought index considers atmospheric demand for moisture to predict drying conditions earlier.
The National Science Foundation has awarded Lehigh University $6 million to develop a comprehensive, inclusive and accessible research translation ecosystem. The award supports the university's work in engineering, science, health, humanities, business, education and other areas to translate discoveries into practical solutions.
The study found that solely the omicron variant influences cell cycle genes, leading to increased p21 expression and a senescence-associated secretory phenotype. This results in premature cellular senescence, potentially contributing to the reported cytokine storm and development of long-COVID.
Researchers at UW-Madison created a new material that can absorb and trap hydrogen particles, protecting fusion reactor walls from damage. The cold spray coating technology uses tantalum to create a surface that can regenerate itself by expelling trapped hydrogen.
Researchers combined diamond and lithium niobate onto a single chip to achieve high efficiency in coupling the two materials. This pairing enables stable and reliable qubits, critical for quantum communication networks and applications.
A new method has been developed to produce green hydrogen more efficiently and cheaply, using ruthenium particles and a solar-powered electrolytic system. The technology could reduce the costs of green hydrogen production on an industrial scale.
Researchers explore the properties of cytostatic persisters in cancer treatment, highlighting their therapeutic potential and challenges. The study suggests that targeting these persisters before resistance emerges can reduce cancer recurrence.