Articles tagged with Drug Abuse
A 22-year study found that early adolescence and peer influences are precursors to later drug use, which leads to increased health problems. Researchers tracked over 600 youths from age 1 to 27 and found that rebelliousness, distrust of authority, and risk-taking behavior were associated with later substance abuse.
Research reveals distinct patterns of use among methamphetamine and cocaine abusers, with meth users more likely to experience attention and organizational difficulties. Cocaine users, on the other hand, tend to consume the drug primarily in the evening, leading to differences in cognitive impairment.
A study by Dr. Steven L. Batki found that methadone treatment significantly improved the completion of TB therapy in opioid-dependent patients with latent TB infection. Patients receiving standard or minimal methadone treatment had higher completion rates compared to those receiving routine care.
Scientists followed nearly 2,000 HIV-infected patients with varying levels of hepatitis C exposure. They found that exposure to hepatitis C did not increase risk of death or AIDS progression but was associated with lower antiretroviral therapy prescriptions, which may lead to increased mortality rates in this group.
A study of 144 physicians found that treating substance-abusing patients leads to lower professional satisfaction rates compared to caring for patients with hypertension. The findings suggest that addressing physician dissatisfaction in drug abuse treatment may improve patient outcomes.
A study of 373 intravenous drug users found significant reductions in emergency department use among those using needle-exchange programs, including Hispanics, men, and those with mental illness. The study suggests that needle-exchange-based health care services can reduce emergency department use among high-risk IDUs.
A study by NIH/National Institute on Drug Abuse found that integrated medical and substance abuse treatment significantly increased patient continuation rates. Over half of patients who received comprehensive care entered outpatient substance abuse programs, compared to just 2.4% of those receiving standard care.
A study by Troost found Botox to be an effective preventive therapy for headache treatment, with 92% of patients experiencing improvement after four treatments. This alternative approach can reduce medication use and side effects, offering a promising solution for debilitating headaches.
The ASU School of Social Work has received a $1.6 million grant from the National Institutes of Health (NIH) to strengthen and expand social work research on drug use. The consortium, led by Flavio Francisco Marsiglia, will focus on historical cultures of the Southwest and community-based needs assessments.
A study found that homeless sexual minority youth are more likely to experience physical and sexual abuse, with bisexual individuals reporting the most incidents. These young people face significant challenges in their lives, including heavy substance abuse and difficulties dealing with their sexual identity.
A team of scientists discovered a brain signal that encourages us to continue working on tasks to receive rewards. Abnormal activity in this signal may contribute to conditions like obsessive-compulsive disorder or drug abuse.
Research finds significant cognitive impairments in crack-dependent and crack-and-alcohol-dependent individuals after 6 weeks and 6 months of abstinence. The largest effects were found in executive function and spatial processing assessments.
Following the 9/11 attacks, a study found that nearly one-third of respondents increased their use of alcohol, marijuana, or cigarettes, with the largest increase in alcohol consumption. The study also found that people experiencing post-traumatic stress disorder (PTSD) and depression were more likely to engage in substance abuse.
A recent international study revealed that teenage drug abuse is significantly lower for those living with both parents and enjoying high-quality family relationships. The study found that having a strong attachment to the mother was particularly effective in preventing drug use, even in areas of high peer pressure.
A NIH-funded study found that family-based interventions can save an average of $119,633 in avoided costs for society per case prevented. The Iowa Strengthening Families Program and Preparing for the Drug Free Years intervention programs were effective in reducing adolescent alcohol use.
Researchers have made significant discoveries about the molecular mechanisms underlying addiction, memory formation, and brain plasticity. A key molecule called AP1 has been found to play a crucial role in controlling synaptic changes, which are more extensive than previously thought and resemble those induced by real experience.
A study of 101 newborns found that 40% tested positive for drugs, with cocaine and heroin being the most common. The researchers argue for more funding on rapid-screening technology and better educational outreach to prevent drug exposure during pregnancy.
A study found that individuals carrying a high-output version of the dynorphin gene are less susceptible to cocaine dependence. The genetic association suggests a possible neurobiological function for this particular variant, which may modulate cocaine's effects and increase protection against addiction.
A brain-imaging study has shed light on the reasons behind inhalant abuse by revealing how toluene moves into the brain rapidly and affects reward centers. The study shows that toluene spreads more generally to the entire brain before clearing the body, which may explain its addictive potential.
A study of over 40,000 young participants found that marijuana smokers are more likely to have the opportunity and try hallucinogens. By age 21, nearly half of marijuana smokers had tried a hallucinogen, compared to one in 16 who had never smoked.
Researchers have identified a key gene that increases the risk for drug abuse, affecting not only alcohol but also nicotine. The 'AA' configuration of the mu-opioid gene was found in nearly 90% of individuals with substance abuse issues.
A new study found that alcohol and nicotine interact in the brain's dopamine system, suggesting a link between the two addictive behaviors. Rodent studies showed that combining alcohol and nicotine increased dopamine release, while blocking nicotinic effects with mecamylamine reduced alcohol's pleasurable effects.
Researchers found that nicotine prolongs the reward period by disabling the system that counterbalances its pleasant effects. This results in an enhanced ability to reinforce smoking behavior, making it challenging for people to quit despite the severe health consequences of tobacco use.
The Center for the Study of Pharmacologic Plasticity in the Presence of Pain at Wake Forest will study changes in the spinal cord caused by certain medicines and their impact on pain sensation. The research aims to develop new, effective pain treatments for patients with nerve injury or neuropathic pain.
A functional polymorphism within the m-opioid receptor gene has been linked to an increased risk of substance abuse, including alcohol and other substances. The study found that individuals with this genetic variation were more likely to develop addiction and engage in risky behavior.
A study of patients entering detoxification for alcohol and other drug dependence found that serious injury is common among those with alcohol dependence. The study suggests that problems with alcohol, rather than illicit drugs, are associated with increased risk of injury.
A bodybuilder admitted to hospital with blackouts, abnormal heartbeat, and symptoms attributed to bromocriptine, a drug easily obtained online. Many professional bodybuilders use bromocriptine to burn fat during training, highlighting the ease of access to prescription-only drugs through the internet.
A study conducted by Yale University has shown that a cocaine vaccine can significantly reduce cravings and addiction in patients who abuse the drug. The vaccine was found to be safe and effective in increasing anti-cocaine antibodies, which help prevent the uptake of cocaine across the blood-brain barrier.
A Yale researcher found that men who witnessed combat are at risk for various current adverse outcomes, including post-traumatic stress disorder and job loss. The study suggests that providing quality mental health care and social services to veterans could mitigate these effects.
Research shows that social hierarchy influences brain function related to cocaine addiction in non-human primates. Dominant monkeys exhibit reduced dopamine levels and lower likelihood of abusing cocaine after being housed in social groups.
Researchers identify potential link between serotonin-enhancing drugs and increased risk of cerebrovascular syndrome (stroke). The study suggests that caution should be exercised when combining medications that contain serotonin enhancers, particularly in patients presenting with sudden-onset headaches.
Researchers found that certain drugs, including alcohol and cocaine, increase beta endorphin levels in the nucleus accumbens, a brain region influencing addiction. This discovery may lead to the development of medications targeting this system to help individuals overcome addiction.
The University of Pittsburgh will conduct a long-term study on the impact of alcohol use and abuse on aging veterans with and without HIV. The study, VACS 5, aims to identify health and quality of life effects of alcohol consumption among this population.
Recent studies show that methamphetamine acts on the same brain mechanisms as cocaine and alcohol, disrupting dopamine receptors and glucose metabolism. Researchers found damage to brain cells may recover after prolonged abstinence from the drug.
A new study finds that methamphetamine abusers have fewer dopamine receptors, leading to reduced motivation and drive. The study suggests that the drug's high dopamine release overactivates the brain's reward system, making it hard for addicts to resist.
A study found that dopamine transporter levels improved in methamphetamine abusers after prolonged abstinence, suggesting potential for recovery. However, cognitive and motor function did not show significant improvement, highlighting the need for further research.
UB researchers found that Ritalin can cause long-lasting changes in brain cell structure and function, similar to other stimulant drugs. The study suggests that Ritalin's effects may outlast the initial dose, leading to concerns about its long-term impact on the brain.
The Combining Medications and Behavioral Interventions (COMBINE) study evaluates the effectiveness of behavioral treatments alone and in combination with medications for treating alcoholism. Researchers at Yale University are recruiting participants to participate in the study.
A UCSF study found that patients with substance abuse-related medical conditions benefit from integrated medical and addiction treatment, leading to improved abstinence rates and reduced inpatient use. The two-year study showed no significant differences in total abstinence rates between the integrated and independent care groups.
Scientists have discovered a process in the brain's cannabinoid system that may lead to new medications preventing relapse to cocaine use. Researchers found blocking this receptor can prevent rats from seeking cocaine after exposure to cues or stress, offering hope for developing new treatments.
Researchers found that divalproex sodium reduced the need for oxazepam and slowed worsening symptoms in a seven-day study. The anticonvulsant's anti-kindling properties may prevent nervous system hyperexcitability during alcohol withdrawal, making it a viable treatment option.
Researchers found that using rewards with naltrexone significantly improved treatment retention and naltrexone compliance. Patients who earned vouchers for drug-free behavior saw an increase in these outcomes.
A new therapy has been found to be effective in helping women overcome their concerns about gaining weight when quitting smoking. The study, published in Journal of Consulting and Clinical Psychology, found that 21% of women who received therapy had completely quit smoking with no relapses.
Researchers propose individualized risk-benefit assessment to determine treatment for illicit drug-using patients. They argue that withholding treatment is unfair and ineffective, citing success stories from AIDS treatment.
A study published by researchers at the University of Chicago Medical Center found that prenatal exposure to methamphetamine increases the risk of brain disorders, such as Parkinson's disease, in male offspring who later take the drug themselves. The toxic effects of methamphetamine can hasten the onset of these conditions.
A large-scale study evaluated community-based treatment programs for adolescents, finding significant reductions in drug use and improved mental health outcomes. The study also identified the importance of minimum length of stay in treatment for optimal results.
Researchers found that after stopping cocaine use, individuals become more sensitive to drug-associated environmental cues, leading to increased cravings and a higher risk of relapse. The study suggests that treatment programs must consider this persistence of craving beyond the acute withdrawal phase.
A recent study found that adolescents who participated in community-based treatment programs significantly reduced drug use and criminal behavior, and improved academic performance. Longer stays in treatment were associated with better outcomes.
A recent study found that individuals clinically identified as substance abusers have an elevated risk of injury. Alcohol-and-drug abusers had the highest risk of injury, followed by those who abused only one type of substance.
The Walking A Good Path calendar is an inspirational and educational resource developed by NIDA and American Indian organizations. The calendar shares current science-based information on drug abuse, addiction, prevention, and treatment, highlighting the health risks and effective strategies for Native American communities.
A new Yale research program aims to bridge the knowledge gap on women and drug abuse, providing training opportunities for scholars to develop sex-specific treatments and prevention strategies. The five-year program will focus on understanding the etiology of drug abuse in women and its impact on families.
The National Drug Abuse Treatment Clinical Trials Network has expanded to include 11 regional research centers and nearly 70 community-based treatment programs. The five newly funded centers will receive $11 million over five years, bringing the total funding for all 11 components to $121 million.
Researchers at the National Institute on Drug Abuse found that squirrel monkeys will self-administer intravenous injections of THC, a psychoactive compound in marijuana, in doses comparable to those used by humans. This study suggests that marijuana has similar abuse potential as other addictive substances like cocaine and heroin.
Researchers found that methoxsalen inhibits CYP2A6 enzyme, increasing nicotine levels and reducing smoking desire. The medication was shown to improve oral nicotine replacement effectiveness in reducing cravings and puff counts.
Scientists have found that cocaine abuse coupled with use of alcohol leads to impulsive decision-making and poorer performance on tests of learning and memory. The negative effects persist for at least a month after substance use stops, according to the study published in Neurology.
Long-term methamphetamine abuse can cause permanent brain cell damage, similar to Alzheimer's disease and stroke. The study found reduced levels of N-acetyl-aspartate and increased levels of myo-inositol and choline-containing compounds in the brains of abusers.
Research funded by NIDA explores how craving tobacco increases urge to use illicit drugs. Studies found that smokers who use illegal drugs have a harder time quitting their drug habit than nonsmokers.
Two studies found that heavy smoking is linked to increased craving for illicit drugs, including cocaine and heroin. Researchers suggest that smoking cessation programs should be offered as part of other drug treatment programs to combat this trend.
Researchers find substance use and dependence are significant problems among welfare recipients, but academic skill deficits are a greater barrier to self-sufficiency. Effective services addressing mental health needs and providing support for work barriers are crucial for successful fulfillment of family roles.
A Penn State researcher found that nearly three-fourths of women addicted to crack cocaine engage in prostitution to support their habit, highlighting the need for comprehensive support services. The study suggests that programs should offer housing, education, and job training to help these women escape poverty and addiction