A study of 352 patients found that sirolimus-eluting stents significantly improved minimum coronary artery diameter at 8 months, reducing restenosis rates by 42% and major cardiac events by 23%. The technology offers promising results for endoluminal therapy, potentially rivaling bypass surgery.
A team of Purdue biologists has determined the structure of the cytochrome protein complex, critical for photosynthesis in a blue-green bacterium. The study reveals the entire mechanism of photosynthesis and its energy flow, shedding light on animal metabolism.
The Voice Academy website, funded by a NIDCD grant, provides virtual classrooms and resources for kindergarten through high school teachers to learn about voice health and prevention. The site aims to help teachers address voice problems, such as hoarseness and fatigue, with behavioral changes and expert advice.
Researchers discovered that neighboring non-neuronal cells can protect or rescue motor neurons from degeneration when they carry an ALS mutation. This finding suggests the potential of stem cell replacement therapy targeting non-neuronal cells to treat ALS. The study used mouse models with a mutation in the gene superoxide dismutase (S...
Researchers at CU-Boulder created more efficient 'soft' x-ray light in the water-window region using a femtosecond laser, making it possible to build compact microscopes for biological imaging. This advance could visualize processes within living cells and understand how pharmaceuticals function.
The study found that gastric bypass surgery significantly improved diabetes outcomes in patients, with nearly all achieving normal blood sugar levels and reducing their reliance on anti-diabetic medications. Patients with shorter disease durations and milder type 2 diabetes saw the greatest improvements in glycemic control.
A comprehensive human protein database has been launched, featuring 3,000 entries on protein roles in health and disease. The database includes protein interactions, disease genes, and other information, making it easier for researchers to connect observations and create new hypotheses.
The Institute for Genomic Research has released sequence data for the Trichomonas vaginalis parasite, which causes trichomoniasis and is linked to increased HIV transmission. The larger-than-expected genome holds promise for finding new treatments and prevention strategies.
The Blanke Lab will conduct fundamental research about anthrax and methods to neutralize its impact, with a goal of generating novel therapeutics and vaccines. This project is part of the Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, bringing together leading researchers from various disciplines.
Research suggests that low and high birthweights are associated with a higher risk of cerebral palsy. Babies born with weights below the 10th percentile or above the 97th percentile had a four to six times increased risk, respectively.
Tufts University has been awarded a $25-million NIH contract to collaborate with the University of Massachusetts on developing ways to diagnose and treat botulism poisoning, one of the most dangerous bioterrorism threats facing the US. The research will focus on identifying human pathogens that can cause disease in food or water.
A recent study by the USGS found that 20% of homes in Hillsborough, Rockingham, and Strafford counties have arsenic concentrations above 10 micrograms per liter. In some areas, the incidence is as high as 30%. The study highlights the importance of testing private wells for arsenic to protect public health.
Researchers at Penn aim to understand factors influencing poor prostate cancer outcomes among African-American men, including biological, environmental, and behavioral aspects. The study's findings may help develop better tools for prevention and treatment, ultimately improving clinical outcomes for this underserved population.
Researchers identified cardiovascular abnormalities in 39% of participants, highlighting the need for early recognition and treatment. The study suggests that effective treatment can prevent 90% of heart attacks and strokes.
A study found that using aggressive chemotherapy with high doses of methotrexate, asparaginase, and doxorubicin improves survival rates for children with T-cell acute lymphoblastic leukemia by 15 percentage points. The new approach also showed minimal long-term effects beyond those seen in lower-dose treatment regimens.
A team of Purdue University researchers has identified the genetic mechanism responsible for dwarfed appearance in corn and sorghum plants. This finding may help develop dwarf forms in other crops, improving food production in certain regions. The study also reveals a genetic phenomenon involving direct duplication that causes instabil...
Case Western Reserve University researchers will continue their study on children prenatally exposed to cocaine, now in their 14th year of funding, due to a new $4.9 million grant from the National Institute on Drug Abuse. The ongoing research has found associations between prenatal cocaine exposure and cognitive skills development.
Researchers discovered that healthy astrocytes and glia can rescue motor neurons containing ALS-causing mutations from degeneration. The study suggests inserting healthy astrocytes into ALS patients may reduce or prevent motor-neuron degeneration.
A study by Massachusetts General Hospital researchers found that blood vessel development is intricately linked with fat tissue formation. This interaction can be controlled to develop new treatments for cancer and obesity, as well as support the growth of new organs.
A study found that vibrating insoles can significantly improve balance and reduce sway among elderly participants. Younger individuals also showed reduced sway with stimulation, suggesting the potential of noise-based devices to enhance motor control performance.
Researchers have resolved a long-standing paradox surrounding lung collectins, finding they play two roles in the lungs: dampening and promoting immune responses. This discovery sheds light on how these versatile proteins protect against both harmful pathogens and excessive inflammation.
Researchers developed a new technique to detect melt pond coverage on Arctic sea ice using NASA's Landsat 7 satellite. This method improves the understanding of the Arctic heat balance and its impact on global climate.
A study of 100 patients found that nearly a quarter had pivotal physical findings, leading to changes in diagnosis and treatment. These findings prompted collaboration with specialist consultants to perform urgent procedures, highlighting the importance of skilled physical exams in hospital care.
A large study of nearly 44,000 healthy men found no association between dietary fat intake and stroke risk. The research suggests that saturated fat intake may actually be beneficial in reducing atherosclerosis, contrary to previous findings.
Under the contract, TIGR will sequence dozens of genomes per year to provide data for vaccine and antimicrobial drug development projects. The institute's affiliated facility has already conducted sequencing for over 50 organisms, including microbes that cause various diseases.
Researchers found that higher religiosity levels in countries do not necessarily lead to stricter moral standards on sex. In fact, individual religiosity has a minimal effect on cheating on taxes due to existing laws.
Researchers found neurons in the anterior cingulate cortex (ACC) respond to discrepancies between intentions and actual events, indicating that the brain monitors the consequences of actions. The study used detailed studies measuring neural activity in macaque monkeys performing tasks requiring self-control.
Researchers at UCSD have identified chemicals that can protect cells from the effects of the toxin, raising hope for a novel treatment for Pseudomonas infections. The study found that ExoU toxin kills cells by targeting cell membrane phospholipids, but alternative treatments may be possible.