Researchers tested Seroquel on 542 patients with bipolar depression, finding that 50% responded quickly to treatment and experienced reduced suicidal thoughts. The study's findings suggest a potential new standard of care for bipolar disorder.
A study of minor league baseball players found early damage to the hands of healthy players due to catcher's mitt design. The research revealed significant blood vessel damage and hand weakness among catchers despite using protective padding.
Animal research suggests a potential new treatment target for epilepsy by blocking a specific brain pathway involved in seizure spread. The treatment could be more effective and have fewer side effects than current therapies.
Research estimates a lifetime cancer risk of 0.14% and 0.022% from virtual colonoscopy, with the colon, stomach, and bladder being at greatest risk. While low radiation risks are promising, practical issues such as bowel preparation and patient compliance remain to be addressed.
Scientists at The Wistar Institute discovered that poor T cell responsiveness limits current approaches to therapeutic vaccines. They found that the immune system's ongoing stimulus during chronic infection prevents optimal response to vaccines, which may be improved by lowering viral load or enhancing T cell function.
A new study found that higher adolescent IQ and greater activity levels are associated with a lower risk of dementia and mild cognitive impairments. The research used historical data from high school records and interviews with graduates to explore the relationship between early-life factors and late-life cognitive status.
A new Penn State study found that a balanced diet with both polyunsaturated fatty acids (PUFAs) and monounsaturated fatty acids (MUFAs) is essential for lowering cholesterol levels. The study compared two heart-healthy oils, sunflower oil and olive oil, in a diet designed to reduce blood cholesterol.
Researchers at KEK Laboratory in Japan have observed a new type of interaction among quarks, producing evidence of a beauty quark converting to the lightest down quark. This observation allows for study of fundamental laws of the universe and potential validation or discovery of new physics models.
Researchers at USC discovered that anti-angiogenesis drugs increase glucose regulated protein 78 levels, blocking cell death and leading to drug resistance. Suppressing GRP78 gene expression can overcome resistance to chemotherapy drug etoposide.
Researchers show that HIF-1 alpha regulates bactericidal agents and enhances expression of bacteria-killing cells. Increasing HIF-1 activity increases the killing capacity of phagocytes, providing a novel approach to treating bacterial infections.
Research found no reduction in long-chain polyunsaturated fatty acids in breast milk of women who exercised moderately. Elderly people using herbal supplements are less satisfied with conventional medical care and often hide supplement use from doctors.
The new center will explore basic biological mechanisms and translational research on muscular dystrophies, while providing advanced diagnostic services to patients. Researchers will investigate new treatments for Duchenne muscular dystrophy and develop mouse models to test potential therapies.
The Protein Structure Initiative (PSI) has reached its rapid production phase, aiming to determine thousands of protein structures using innovative approaches and tools. The new centers will use methods developed during the pilot period to rapidly generate protein structures found in organisms ranging from bacteria to humans.
Researchers discovered that induction of the HIF-1 pathway can act as a 'super-antibiotic', increasing bacterial killing in low-oxygen environments. Additionally, studies on skeletal muscle and kidney regeneration found that these organs' natural repair mechanisms play a crucial role in maintaining function and tissue health.
Researchers have found that women carrying a certain immune system gene and not having HPV16 are three times less likely to resolve their precancerous lesions. This discovery could provide better targets for cervical cancer vaccine development and potentially allow women to avoid surgery, according to Johns Hopkins scientists.
Researchers used high-resolution DNA scanning to identify regions of chromosomes with genetic errors in lung cancer cells. The study found five new areas with copy-number changes, including deleted and over-copied genes, which could lead to targeted therapies.
Researchers found that over half of the 46 known microRNAs are essential for development, affecting it in specific ways. MicroRNAs regulate fundamental processes such as body patterning, morphogenesis, and nervous system development.
Argonne National Laboratory has received a $50 million NIH grant to expand the information available to researchers on biomedically important proteins. The grant will refine existing methods for structure determination, making it possible to produce over 250 protein structures per year.
A multi-site study found Risperidone effective in decreasing aggression, repetitive behaviors, and increasing social interaction in children with autism. The medication showed limited side effects, supporting its use as an intermediate-term treatment option.
The Joint Center for Structural Genomics will determine a large number of high-resolution structures of biological molecules using new methods and technologies. The researchers aim to tackle challenging structures such as large protein assemblies and proteins essential for all organisms.
Research found that children born full term but weighing less than 5.5 lbs had a 50% increased risk of psychological distress in later life, regardless of childhood factors. The study suggests that early factors before birth may be important in increasing vulnerability to depression in adult life.
Scientists at UCSD found that white blood cells increase production of protein HIF-1 in response to bacteria, stimulating antimicrobial compounds to kill invading organisms. Treating white blood cells with chemicals can enhance their bacterial killing ability.
A study of 2,819 respondents in western Norway found that exposure to pre- and post-natal tobacco smoke increases the risk of adult asthma. The researchers estimated that almost a quarter of cases of adult asthma could be prevented if children were not exposed to environmental tobacco smoke.
A new study of 229 children found that regular snoring in childhood is linked to an increased risk of developing hyperactive behavior. The study also found that other symptoms of obstructive sleep apnea, such as daytime sleepiness, can predict future behavior problems.
The July 2005 issue of Ophthalmology features groundbreaking research on glaucoma treatment and intraocular pressure management. Studies also explore the correlation between macular detachment height and visual outcome, as well as the efficacy of pars plana vitrectomy for managing inferior breaks in pseudophakic retinal detachment.
A recent study using 'ecological footprint' accounting found that the US benefits from using fuel ethanol do not outweigh its significant environmental impacts. The research suggests that relying on ethanol to fuel the automobile fleet would require enormous areas of corn agriculture, outweighing any potential energy gains.
A new map of microbial evolution reveals that more than 600,000 genes have been transferred horizontally among species over billions of years. This finding challenges the traditional tree-like representation of evolutionary relationships and highlights the importance of horizontal gene transfer in shaping microbial communities.
A US delegation of 22 researchers led by Dr. Wright participated in a workshop with Japanese researchers, exploring topics like network forensics and biometric key encapsulation. The event aimed to promote bilateral cooperation in protecting critical information infrastructure.
Researchers have identified techniques to detect soils that inhibit soybean cyst nematode populations, a major cause of yield losses in the US. These methods can be used to promote soil health and reduce environmental impact by using nematode-suppressive soils.
Researchers used ocean sound waves to track the Indian Ocean tsunami quake's movement, revealing a slower speed than expected. A new model for raindrop formation may improve understanding of Earth's climate and cloud formation.