A radical proposal suggests that California's CIRM could accelerate the development of stem cell therapies by implementing a patent pool and a shared prize system. This approach aims to stimulate innovation, make treatments more affordable, and establish a new medical innovation model for the 21st century.
A study by Columbia University researchers finds that living in neighborhoods with a mix of residential and commercial uses and access to public transportation can lower obesity rates. The research also suggests that subtle lifestyle changes repeated over time can have a significant impact on body size.
Researchers at Emory University Health Sciences Center successfully transplanted porcine islets into nonhuman primates, achieving insulin independence. The study suggests that xenotransplantation using CD28/CD154 costimulation blockade may be a safe method for reversing human type 1 diabetes.
Researchers found combined therapy improved survival rates for patients with AIDS-related lymphoma, comparable to non-HIV patients with lymphoma treated with CHOP. For standard-risk ARL patients, 79% achieved complete remission and 50% survived after 47 months.
Research projects focusing on Aboriginal women's self-care, mental health consumers' recovery, and psychologists' role in the Mental Health Service have been allocated funding. The programs aim to build research capacity with the health region through collaborative education processes.
A multicenter trial of two spinal cord injury therapies found that weight-supported treadmill training and conventional overground mobility therapy produce similar outcomes. The study showed that individuals with partial spinal cord injuries can walk independently by six months, regardless of the therapy strategy.
Professional football coaches exhibit conservative behavior when making decisions, prioritizing the risk of losing over potential gains. Despite this, research suggests that such behavior can have significant consequences, including decreased team performance.
A neoprene suit, called NASG, can save lives of women suffering from obstetrical hemorrhaging due to childbirth by reversing shock and decreasing bleeding. The study found a 69% decrease in death and severe illness among patients treated with the NASG.
Research author Dr. Tarja Ketola suggests that companies using psychopathic practices can overcome mental burdens by integrating personal and professional values. By applying virtue ethical values, 'psychopathic' companies can move towards ideal responsibility and genuine corporate responsibility.
Researchers use functional magnetic resonance imaging to investigate the brain regions involved in illusory tactile perceptions. The study finds that the same sector of the brain is activated whether the sensation is real or illusory, suggesting a connection between conscious perception and somatotopic cortical processing.
Researchers say cannabidiol, a compound found in marijuana, may protect the eye from growing leaky blood vessels and prevent diabetic retinopathy. Early studies indicate it works as an antioxidant to neutralize toxic superoxides and inhibit destructive systems.
A recent study published in Diabetes reveals that diabetes rates in the US have increased dramatically over the past decade, leading to a sharp rise in hospitalizations and deaths from coronary heart disease. As a result, progress made in reducing illnesses and deaths from this condition may be put at risk.
A study in a Venezuelan reservoir found that predator-free islands had significantly fewer plant species and smaller sapling densities than larger land masses. The researchers concluded that the presence of predators is essential for maintaining biodiversity and preventing ecosystem collapse.
A portable cocaine sensor has been developed at UC Santa Barbara, enabling rapid detection of illegal substances in bodily fluids. The sensor is based on a generic, inexpensive method that can detect a range of targets, including prescription drugs and bioterrorism agents.
Researchers have identified the genetic sequence of the USA300 strain, which has incorporated parts of another bacterium's genome, enabling it to evade host immune responses and survive. This discovery provides a diagnostic tool to monitor the spread of the strain in hospital and community settings.
A study found a strong association between meniscal malposition, meniscal tears, and cartilage loss in knee OA. Meniscal damage increased the risk of cartilage loss, particularly in the medial tibiofemoral joint.
A recent study found that antibodies targeting the Chagas parasite also block rhodopsin, a molecule essential for converting light into electrical impulses. This discovery sheds light on the molecular mechanisms underlying the disease's vision problems. Researchers hope to develop new drugs or vaccines to combat the parasite and improv...
Experts warn that sharing study results with participants could negatively impact their future health due to potential regret over less effective treatments. A revised informed consent strategy is proposed to balance individual rights with the need for transparency.
Devices called PALs can detect sounds coming from ships, whales, volcanic eruptions, rainfall, and breaking waves. By analyzing these sound sources by frequency, researchers can create a 'sound budget' that helps establish noise regulations for different ecosystems.
US chemical companies experienced a modest increase in sales and earnings in Q4 2005, driven primarily by the impact of hurricanes on plant closures and transportation. Sales rose 7.5% to $38.1 billion, while earnings increased 0.9% to $2.31 billion.
A new study suggests that Tijuana's HIV infection rate may be close to three times higher than Mexico's national average, posing a significant public health threat. The researchers emphasize the need for urgent intervention and prevention strategies targeting high-risk groups.
A comprehensive scientific study explores the impact of social supports, spirituality, and religiousness on quality of life and long-term recovery from addiction. The research found that participation in 12-step fellowship programs and social support networks significantly enhances recovery outcomes.
Researchers found that Culex mosquitoes changed their feeding behavior from American robins to humans in the fall, leading to large-scale outbreaks of disease. The study's findings suggest a continent-wide phenomenon and may explain why West Nile virus outbreaks are more intense in the US than in Europe and Africa.
A study at Cedars-Sinai Medical Center found that angioplasty with drug-eluting stents resulted in outcomes equivalent to bypass surgery for patients with left main coronary artery disease. The treatment was shown to have similar short- and intermediate-term clinical outcomes, despite higher risk patient demographics.
Researchers replaced a faulty gene responsible for hemophilia with a transposon from fish, preventing profuse bleeding in neonatal mice. The approach holds promise for treating the most common form of hemophilia, affecting nearly 18,000 Americans.
Scientists aim to capture ultrafast electron motion using extreme ultraviolet pulses, enabling study of electronic transportation in nanomaterials and biological samples. The proposed attosecond pump-probe technique has potential applications for chemists to design special molecules.
A University of Michigan study suggests that 96% of the gender difference in death risk after coronary artery bypass surgery may be due to differences in infection. Women were more likely to have infections, but once infected, men had higher mortality rates.
A study of 470 Dutch men aged 65-84 found that regular cocoa consumption was associated with lower blood pressure and a significantly reduced risk of death from all causes, including cardiovascular disease. The benefits were not attributed to lowering blood pressure alone but may be related to flavan-3-ols and antioxidants in cocoa.
Researchers identified a specific protein pattern that can distinguish bladder cancer patients from healthy controls and others with similar symptoms. This discovery has the potential to predict tumour stage, recurrence, progression, and treatment response in bladder cancer patients.
Researchers found a substantial link between severe rheumatoid arthritis and increased risk of lymphoma. Patients with high RA activity experienced a 70-fold increase in lymphoma risk, while those with low activity had an 8-fold increase.
Researchers found that hepatic arterial infusion (HAI) therapy extended survival and improved quality of life in patients with colorectal cancer that has spread to the liver. HAI therapy resulted in a median survival of 24 months, better response rates, and longer time to disease progression compared to systemic chemotherapy.
A recent study found that women are more likely to develop infections after coronary artery bypass graft (CABG) surgery, leading to a higher risk of death. The researchers discovered that urinary, digestive, respiratory and skin and subcutaneous tissue infections were more common in women than men.
The article highlights the need for researchers to navigate intricate legal, ethical, and political issues surrounding human embryonic stem cell research. The author, Henry T. Greely, emphasizes that these concerns will significantly impact researchers, institutions, and science as a whole.
A team of researchers, led by Giulia Galli at UC Davis, used a supercomputer to investigate the structure of liquid water. They found that water molecules may not cluster in tetrahedral groups as previously thought, but instead form rings and chains.
A study by the North Central Cancer Treatment Group found that reducing epoetin alfa dosing frequency from once weekly to every three weeks did not significantly impact hemoglobin levels or require transfusions. Patients in both treatment groups reported similar quality of life at the end of the 21-week study.
The Laser Scaling Device uses twin lasers to add scale to photographs, allowing investigators to measure the size of objects in images. This technology facilitates fast and accurate measurement analysis of digital evidence, facilitating serendipitous evidence detection and improving crime scene investigations.
Researchers successfully produced blood vessels within heart muscle tissue, showing significant improvement in heart function. The tissue-engineered construct remained viable even after three weeks of implantation, maintaining cardiac specific function.
Neural transplants have provided long-term clinical benefits to three patients with Huntington's disease, improving motor and cognitive function. The procedure also led to focal improvements in brain metabolic activity, while secondary clinical alterations were observed due to the ongoing disease process.
A study of 3,778 individuals found that 52.1% of those with circulatory disorders continued to smoke. Only 3.4% of smokers had received counselling in the past year.
A report by the University of Toronto Joint Center for Bioethics advocates for a global network of scientists to balance biodevelopment and biosecurity. The proposed strategy aims to create conditions for fighting bioterrorism by building capacity for scientific discovery, particularly in developing countries.
A large-scale search for new drugs to suppress autoimmune disease symptoms led researchers to a biochemical mechanism involving gold compounds. Gold, particularly in its special form, renders MHC class II proteins inactive, a key component of the immune system involved in autoimmunity.
Diabetic rhesus macaques achieved sustained insulin independence after receiving neonatal porcine islets transplanted with an anti-rejection protocol. The study's success suggests that xenotransplantation may be a viable solution for type 1 diabetes treatment.
Researchers at University College London discovered that brain activity before an event is linked to memory recall. The study used EEG scans to show that preparing the brain for a task can enhance long-term memory, and that this preparation can be done by being 'in the right frame of mind' and staying alert between cues.
Researchers found KCNC3 gene mutations in two families, one with adult-onset ataxia and the other with childhood-onset ataxia and mild mental retardation. These findings suggest that potassium channel abnormalities may contribute to a wide variety of neurodegenerative diseases.
A study of 76 adolescent hamsters found that anabolic steroid use led to increased aggression, lasting up to two years and affecting brain chemistry. The research suggests that humans may experience similar long-term behavioral problems if they abuse steroids during adolescence.
Researchers found that a common osteoporosis treatment helped men with prostate cancer recover significant bone mass after two years of androgen deprivation therapy. The study suggests that bone density tests should be encouraged for men at risk, and bone-preserving therapy could prevent debilitating fractures.
A study of 700 autopsy cases found that retinal hemorrhages occur more frequently than initially thought and are not always indicative of child abuse. The research suggests that doctors should consider other possibilities when evaluating children with retinal hemorrhages, rather than automatically diagnosing abuse.
Researchers found that administration of a bisphosphonate called zoledronic acid every three months significantly increased bone density in men with advanced prostate cancer. The study supports guidelines for monitoring bone density and initiating treatment to prevent fractures.
A new study found that androgen deprivation therapy is ineffective in preventing the spread of localized prostate cancer, despite its increasing use among men with non-spreading disease. Researchers suggest that men may endure significant side effects for uncertain benefits.
A large population-based study found that older men with early prostate cancer who received radiation therapy or surgery lived significantly longer than those who were observed. The study, which examined over 48,000 men between 65 and 80 years old, demonstrated a survival advantage for treatment over observation.
Researchers detected a novel virus, XMRV, in human prostate tumors with two copies of the RNASEL gene mutation. The study validates the use of DNA-hunting 'virus chip' technology to discover previously unknown viruses and potentially uncover new viral causes for disease.
A study at Rice University found that brain activity differs between merged and unmerged dialect groups when hearing similar sounds. This suggests that the merged-dialect group processes the words differently, relying on explicit memory for previous visual stimuli.
Despite growing concern about avian flu, most Americans do not expect a widespread outbreak in humans in the US within the next year. However, many respondents would take precautions to reduce their risk of exposure and report being concerned about the potential economic disruption caused by such an outbreak.
Researchers have discovered consistent genetic differences in the southern house mosquito, explaining the geographical distribution of disease-transmitting strains. The study found that different strains of the mosquito are responsible for serious diseases like elephantiasis and West Nile virus.
A recent study published in Anesthesiology found that xenon was administered safely to patients undergoing coronary artery bypass grafting, showing its potential as a neuroprotectant. The discovery could lead to new treatments for conditions such as strokes and brain injuries, where nerve damage is a major concern.
A study of over 2,371 adolescent girls found that soda consumption nearly tripled while milk intake decreased by over 25% between ages 9-19. This shift is linked to increased risk of osteoporosis and weight gain due to the lack of nutritional value in sodas.
A new study finds that meetings can negatively impact employee well-being for those with high 'accomplishment striving', but positively affect them for those with low striving. Meetings also boost the well-being of individuals who view them as a way to structure their day or network.
Researchers analyzed over 25,000 protein-protein interactions to dispel old notions of what's important about them. The study identified 36 previously unknown interactions and showed that proteins encoded by genes mutated in inherited disorders interact with known disorder-causing proteins.
The Maintainer's Electronic Performance Support System (MEPSS) is a software developed by the Georgia Institute of Technology to help military aircraft maintainers work more efficiently. The system provides access to technical information, parts lists, and troubleshooting tips, allowing technicians to diagnose and repair issues quickly.
Using polarized light, NASA scientist Peter Wasilewski analyzes the colors and patterns in ice crystals to determine their type and consistency for various Olympic sports. He also examines snowflake shapes and forms to understand how they affect performance.