Researchers at Oxford University Press USA argue that Queen Elizabeth I wrote a manuscript translation of Tacitus's Annales, based on unique handwriting styles and paper features. The study provides the first substantial work by Elizabeth I in over a century and sheds light on the politics and culture of the Elizabethan court.
LMU researchers found that a central component of the innate immune response is activated by two short RNAs generated by site-specific cleavage of a precursor RNA molecule, mediated by the same enzyme RNase T2. The activation of one receptor, TLR8, is triggered by binding of these degradation products.
Researchers at the University of Waterloo have developed a battery-free device called Tip-Tap that allows users to navigate computers using only their fingertips. The device uses radio frequency identification tags and can be integrated into gloves or attached directly to the skin as a temporary tattoo.
Researchers employ neural networks to predict molecular bond energies, reducing computational cost and improving accuracy. The combination of AI and quantum chemistry calculations provides an efficient tool for quickly predicting molecular bond energies in complex systems.
Persistent concussion symptoms in children may be a sign of reduced brain function and decreased grey matter, according to researchers at the University of Queensland. The study found that poor sleep was linked to decreases in brain grey matter and reduced brain function, allowing for predictions of recovery outcomes with 86% accuracy.
A new study has found that mussels, introduced to Australia's coastlines, have established themselves and may pose a threat to native species due to genetic pollution. However, the research also suggests that the invasive mussels may bring benefits, such as enhanced tolerance to warm conditions, which could safeguard Australian mussel ...
A study by the European Society of Cardiology found that most patients do not understand or recall information given to them before heart procedures. Patients often believe that opening blocked arteries can cure their heart disease, despite this being a misconception.
Researchers at Harvard University have achieved the coldest chemical reaction in history, slowing down molecules to capture the critical act of bond formation. By utilizing ultracold temperatures, they observed the intermediate stage of the reaction for microseconds, enabling direct measurement and validation of theories.
Researchers at TU Dresden compared bovine sperm from different layers, identifying connections between metabolic rate, motility, and tail length. The study found that faster sperm show higher metabolic rates and longer flagella than non-selected cells.
MIT researchers have devised a novel circuit design that enables precise control of computing with magnetic waves, without any extra components or electrical current. This approach leverages the spin wave property in magnetic materials to produce measurable output that can be correlated to computation.
A rat study found that older mothers' male offspring are more likely to develop heart problems due to changes in placental development and function. The placenta plays a crucial role in supporting fetal growth, but older mothers' placentas show detrimental effects on male fetuses.
Scientists from Skoltech ADASE lab have developed a method to enhance depth map resolution, enabling more realistic virtual reality and computer graphics. The new approach leverages human perception to assess reconstruction quality, outperforming existing methods in visual quality.
Researchers at Harvard's Wyss Institute have developed a high-throughput synthetic biology approach to improve AAV capsid proteins, revealing hidden features and potential new accessory proteins that could help fast-track future gene therapies. The study uses machine-guided design to generate large numbers of high-quality capsid variants.
An international team of scientists found that adopting the Paris Agreement's emission reduction scenario would significantly limit global productivity losses for both fishing and agriculture. In contrast, a no-action scenario would lead to significant declines in productivity for most countries.
Researchers used existing underwater fiber optic cables to create an array of seismic sensors, mapping a previously unknown fault system off California's coast. The technique, known as Distributed Acoustic Sensing (DAS), allows for unprecedented detail in monitoring seafloor seismic activity and potential offshore resources.
A review of randomized controlled trials found that pharmacist-led interventions, such as medication review and patient education, can help prevent cardiovascular disease. Patients who received these interventions experienced significant reductions in systolic blood pressure, hemoglobin A1c, and LDL-cholesterol levels.
A new project by University of Limerick aims to deliver more effective brachytherapy cancer treatment through advanced real-time radiation dose imaging and source localisation. The Origin project has the potential to reduce treatment errors in prostate and gynaecological cancers by up to 55%.
A new report recommends that researchers use expert reviews and computational Big Data approaches to select high-quality chemical probes. The report highlights the value of resources like the Chemical Probes Portal, which provides assessments on 192 chemical probes for 181 different proteins of interest.
A new study reveals an unusual diversity gradient in the Amazon Basin, with higher species richness in the western portion than expected. The research, led by scientists from France and Brazil, analyzed data from 97 subdrainage basins along the main stem of the Amazon and its tributaries.
A new policy brief highlights the risks of an uneven low-carbon energy transition and provides concrete proposals to prevent such risks. The authors recommend focusing on 'just transitions', accelerating technology transfer initiatives, and coordinating financial flows for energy transitions in developing countries.
Researchers developed a new process using biodegradable chitosan nanoparticles to fabricate self-cleaning antireflective glass surfaces. The eco-friendly approach eliminates microplastic waste, a significant environmental concern.
A new study published in the British Journal of Clinical Pharmacology found that pharmacist-led interventions can significantly reduce medical risk factors for cardiovascular events. Pharmacist-led interventions included patient education, medication review, and lifestyle modification, resulting in reductions in systolic blood pressure...
Scientists found Plasmodium PAGRI02, a parasite from Africa, in 5% of European house sparrows. The study, published in Parasites & Vectors, highlights the impact of global environmental changes on wildlife transmission.
A study found that biomass burning in Amazonia can enhance tropical glaciers in the Andes, with aerosols like black carbon increasing melting by 3-4% or 6%. The impact depends on dust content in snow, highlighting climate pressure from global food demand
Experts argue that cyber risk requires collaboration across behavioral science, data science, economics, law, management science, and political science. A unified concept model identifies core questions to understand cyber risk and how each field can contribute to its efforts.
Growing nanoscale polymer brushes on materials' surfaces enables the creation of diverse array of materials with tailored chemical properties. The approach allows for precise control over surface density, length and chemistry, enabling various catalysis and antibacterial applications.
Soil nitrogen levels drive plant growth for food production and ecosystem health. The global field study provides a more detailed baseline of worldwide nitrogen levels, improving understanding of natural cycles and the effects of over-fertilization.
The study investigates the defect dynamics in ceria nanowires under heating using in situ aberration-corrected TEM. The findings show that defects grow into regular rhombic or hexagon shapes at high temperatures, introducing more reactive sites and maintaining the cubic fluorite structure.
A novel elastocaloric cooling material made from nickel-titanium alloy was developed using additive technology, showing high efficiency, ease of scaling-up, and minimal environmental impact. The material demonstrated robust mechanical integrity, withstanding one million cycles without degradation.
A new home urine test has shown to accurately diagnose aggressive prostate cancer and predict treatment needs up to five years earlier than standard clinical methods. The 'PUR' test looks at gene expression in urine samples and provides vital information about tumor aggressiveness.
Women account for one-third of new HIV diagnoses in the Region, with 54% of cases among them being diagnosed late. Early diagnosis is crucial to start treatment and reduce transmission risk, but current systems are failing women and older adults, according to health experts.
Researchers found that Tinder users had limited success in achieving one-night stands, with most gains coming from traditional dating methods. The study suggests that using Tinder does not lead to an increase in short-term sexual relationships.
A new study from iPSYCH found that one in five people with depression have suicidal thoughts despite treatment with antidepressants. The researchers suggest that more intensive treatment could lead to better responses in patients who don't respond to medication within the first few weeks.
A new study has found that babies in neonatal intensive care units (NICUs) are exposed to harmful chemicals such as bisphenol A (BPA) and parabens. These endocrine-disrupting compounds can lead to various health problems, including dysfunctions in children and adults.
New research suggests that ancient microbes played a crucial role in forming massive iron ore deposits and keeping the early atmosphere warm. The findings provide strong evidence for the 'faint-young-sun' paradox theory, which proposes that life emerged on Earth despite a less intense sun.
Humpback whales tend to socialize less in the presence of small fishing boats compared to when there are no vessels present. The noise from boats may be masking their signals, making it difficult for them to communicate and join together.
A study found that disclaimers on retouched photos have no effect on mitigating negative body image in women. In fact, some disclaimers heightened and harmed body dissatisfaction in at-risk women.
A University of Guelph study found that fruit flies' aggression depends on their previous interactions, not just who they're interacting with. The study showed that males in certain social groups became more aggressive after one-on-one encounters.
Researchers used fiber-optic cables to create a seismic network that can detect earthquakes and map fault zones. The technique, known as Distributed Acoustic Sensing, uses laser light to measure strain in the cable, providing detailed images of the ocean floor.
Researchers have developed a new type of solid-state elastocaloric cooling material using 3D printing that exhibits exceptional fatigue resistance and efficiency. The unique nanocomposite structure produced by this method could enable the widespread use of mechanocaloric cooling materials in refrigeration applications.
Researchers developed a method to monitor tropical forest carbon emissions at unprecedented detail using satellite imagery and machine learning algorithms. The approach quantified the economic cost of deforestation in Peru, revealing areas with significant net losses of forest carbon due to logging and land conversion.
A team of scientists has developed an artificial intelligence approach to engineer improved AAV capsids for gene therapy delivery. The research reveals the existence of a previously unknown protein and demonstrates the potential to transform gene therapy. The study's findings have significant implications for the future of gene therapy.
Hematopoietic stem cells can be purified from zebrafish kidneys using a novel purification scheme that allows researchers to collect these elusive cells. The discovery opens up new avenues for studying blood-based diseases and developing medical treatments.
The EuroSea project is an international consortium of 55 partners aiming to improve ocean observation in Europe and beyond. The project focuses on combining existing capacities, filling gaps, and making data available to users more easily.
A study by Duke-NUS Medical School researchers has uncovered new insights into how individual cell types in the brain contribute to Alzheimer's disease progression. The study found distinct gene expression profiles and networks across different cell types, providing potential druggable targets for future drug development.
A new UBC study found that restoring seismic lines to protect caribou from predators and competitors has limited effectiveness in keeping them safe. Caribou populations have declined rapidly across western Canada, and the researchers' camera trap study showed that restored lines were used about as much as unrestored lines.
A team from the University of Tsukuba identifies a novel silencing component called TAF-Iα that plays a crucial role in retroviral silencing during reprogramming. This discovery enables the production of high-quality induced pluripotent stem cells (iPSCs) for regenerative medicine and stem cell therapy applications.
More than half of identified climate tipping points are now active, threatening the Amazon rainforest and ice sheets of Antarctica and Greenland. The scientists call for urgent action to reduce greenhouse gas emissions to prevent key tipping points, warning of a worst-case scenario of a less habitable planet.
Results from NRG-GOG 9929 show that ipilimumab is tolerated in the curative treatment of women with lymph node-positive cervical cancer. The trial found a 12-month progression-free survival rate of 81% and overall survival rate of 90%. Future studies are needed to identify therapeutic targets for improved outcomes.
A study suggests that ancient rock structures on Earth may be mistaken for fossils, which could aid future Mars missions. Research by University of Edinburgh scientist Sean McMahon created synthetic iron-rich formations in the lab, mimicking those found on Mars.
Research reveals disparities in physiotherapy provision across England, with patients in London and the North receiving more, while those in the South West receive less. Factors such as age, gender, and ethnicity impact access to physiotherapy, highlighting a need for parity in service provision.
Researchers at the University of Helsinki developed an artificial intelligence-based algorithm to improve intensive care for patients with severe traumatic brain injuries. The algorithm accurately predicts patient mortality within 30 days, showing promising results in a proof-of-concept study.
Researchers at NTU Singapore have successfully developed a method to generate laser light in Colloidal Quantum Dots using an electric field, reducing the energy threshold by around 10%. This breakthrough brings the prospect of CQD lasers, which could enable low-cost and small-sized lasers with various applications.
A new species of multituberculate mammal, Jeholbaatar kielanae, has been discovered with a distinct middle ear that suggests specialization for feeding. The fossil provides solid evidence of the morphology and articulation of middle-ear bones in multituberculates.
A Scripps Research study found that blocking the kappa opioid receptor while on a restricted-calorie diet resulted in significant weight reductions. Blocking this receptor may be a potential treatment approach for obesity.
Researchers found that kinaesthetic imagery ability enhances golf putting performance, and mental practice can improve a golfer's putting ability even if they already have a good feel for the game. The study suggests that this technique may reduce a golfer's handicap and is crucial in determining earnings on the PGA Tour.
Researchers found that Majungasaurus grew new teeth roughly two to 13 times faster than other carnivorous dinosaurs, replacing them every couple of months. This rapid tooth growth may have been due to the need to gnaw on bones to ingest certain nutrients, requiring exceptionally strong teeth.
Scientists identified a protein in fruit flies that can target mitochondria to reverse disease-causing mutations. This discovery may provide clues about treating human mitochondrial diseases, which currently have no cure. Researchers used three-parent flies to study the influence of nuclear DNA on mitochondrial genome competition.
Researchers have found a new method to identify and manipulate magnetic Weyl semimetals, which could lead to the development of spintronic devices. The new approach uses the relationship between electronic spin and charge to reveal the topological characteristics of these materials.
Recent expert reviews provide valuable updates on vitamin D's role in maternal health, rheumatoid arthritis, respiratory disease, and muscle. Key findings include the importance of routine vitamin D supplementation in childhood and pregnancy to support calcium metabolism.