Researchers developed an algorithm that uses nonsense-mediated mRNA decay (NMD) to predict which cancer patients will respond to immunotherapy. NMDdetective identifies mutations in the genome susceptible to this quality control process, allowing for personalized treatment approaches.
Researchers developed a nondestructive TFM platform allowing for high-throughput cell measurements. The new platform uses a regular array of fluorescent markers to enable zero-stress state measurements, reducing the need for cell removal or relaxation.
The study found that weight-loss surgery significantly reduced healthcare expenditures for veterans with severe obesity over a period of up to 10 years. The observed decrease in medical costs was attributed to improved health outcomes and reduced need for ongoing medical interventions.
Researchers have created tiny, self-propelled robots that can remove radioactive uranium from wastewater. The microrobots use a rod-shaped material called ZIF-8 and propel themselves using hydrogen peroxide fuel, successfully removing 96% of the uranium in an hour.
The researchers developed a method to print silica optical fibers using additive manufacturing, eliminating the need for precise core centering. This allows for the creation of complex fiber designs and applications, such as fiber optic sensors, with reduced costs and improved longevity.
A new study found that calorie labeling in a fast-food restaurant franchise resulted in an initial small decrease of 60 calories per transaction, equivalent to a 4% reduction. This effect was short-lived, with calorie purchases increasing over time.
The Northeast Ohio Tri-County Prevention Infrastructure project aims to prevent alcohol and drug use in youth ages 9-20 using a novel big data analytics system. The system will utilize natural language processing models and machine learning to predict substance abuse trends and issues with high accuracy.
The UMass Amherst team will expand research into the impact of phthalate exposure on male fertility and sperm epigenetics. The study aims to identify epigenetic signatures associated with phthalate exposures and altered sperm function, which may provide better preconception advising for couples.
A new U-M study found that various forms of discrimination are associated with increased rates of depression and suicidal thoughts among African American men. The researchers suggest that expanding current mental health interventions to include culturally relevant suicide prevention resources may be a viable option.
Scientists found 725 different microorganisms in Singapore's air, with bacteria dominating during the day and fungi at night. The discovery reveals a complex community structure that follows environmental conditions and has significant implications for human health and ecosystem sustainability.
Scientists at DOE/Ames National Laboratory have found a broad diffraction pattern in high-quality graphene samples, indicating defect-free and uniform layers of atoms. This discovery enables the reliable identification of structurally perfect graphene, a crucial step towards optimizing its properties for various applications.
Scientists have discovered a clear link between carbon dioxide levels and temperature in the past 2.8 million years, providing a new baseline for understanding climate science. The study reveals that highest CO2 levels matched recent warm periods, while lowest levels did not reach those found in ice ages of the last 800,000 years.
A University of Surrey study suggests that clear guidelines for green infrastructure can maximize benefits and reverse air pollution effects. The researchers argue that housing developers, urban planners, and politicians need easy-to-follow guidelines to create healthier built communities.
A recent NIH-funded study suggests that exposure to acetaminophen during pregnancy may increase the risk of attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in children. The study found that higher levels of acetaminophen exposure were associated with a significantly increased risk of both conditions.
Scientists have successfully created a highly efficient method to convert sunlight into hydrogen using hematite mesocrystal-based photoanodes. This breakthrough improves light-to-energy conversion efficiency and enables large-scale production of clean fuel hydrogen, making it a viable source of renewable energy.
Research shows that losing intact tropical forests results in a 626% increase in climate impact, equivalent to two years of global land-use change emissions. The study highlights the devastating effects of deforestation on the climate and emphasizes the need for better funding and conservation efforts.
Scientists have discovered that human gut bacteria require a unique genetic code to thrive, which is different from person to person. The study found that immunity genes from one bacterium are often shared by others, suggesting a complex and adaptive immune system in the gut.
Researchers at Temple University have discovered that an existing HIV drug can suppress Zika virus infection by targeting a common enzyme. The study opens the door to developing a broad-spectrum treatment strategy for multiple RNA virus infections using the same approach.
A Swedish study found that long-term exposure to traffic exhaust at home increases the risk of stroke in low-pollution environments. The researchers discovered that black carbon from traffic exhaust was the primary culprit, with a 4% increased risk for every 0.3 micrograms per cubic meter.
Researchers at Mayo Clinic have identified a way to slow and reverse fibrosis by targeting a dopamine receptor, which blocks the growth of scar-forming cells. The approach reversed fibrotic processes in lung and liver models, offering a new treatment concept for fibrotic diseases.
A two-legged robot named Little Hermes has been developed to walk, run, jump and interact with the environment synchronously with a human operator. The robot is guided by a person from a remote location who feels the same physical forces as the robot.
A simple saliva test can identify recent spice use in five minutes, helping health professionals diagnose and treat patients. The test also provides information on the type of spice used and concentration.
A new method uses detection dogs and genetic species identification to survey lizard populations without direct contact. The technique was successfully used to identify 78% of 327 samples collected over four years, with most being from blunt-nosed leopard lizards.
The study found that the monsoon system's development was more sensitive to changes in geography than carbon dioxide levels. The monsoon peaked around five million years ago, with 'super-monsoons' stronger than today. Understanding its behavior is crucial for agriculture and industrial development of over 1.5 billion people.
Researchers developed a blood test that measures cell-free DNA (cfDNA) to predict prognosis in glioblastoma patients. The test correlates with progression-free survival and detects genetic mutations not found in solid tissue biopsies, offering a complementary view of the tumor's molecular profile.
Researchers develop self-heating battery to charge EVs in 10 minutes for 200-300 mile range, maintaining 2,500 cycles or half a million miles. Lithium plating reduces cell capacity and causes electrical spikes.
A study published in Lancet Oncology reveals that online popularity of health awareness campaigns does not always lead to increased interest in related health behaviors. Researchers analyzed Google Trends data for specific keywords associated with each campaign and found that only breast cancer-related searches were influenced by the P...
A new study found that certain gut bacteria, such as Bacteroides species, have acquired large immunity gene clusters to neutralize toxins from other bacteria. These clusters are actively acquiring new genes to protect against emerging threats.
Research gaps exist in antibiotic stewardship programs aimed at reducing unnecessary antibiotic use, with a need for standardized processes and outcome metrics. The Society for Healthcare Epidemiology of America calls for additional clinical evidence to inform optimal antibiotic prescribing practices.
A new gene therapy has shown promise in suppressing epileptic seizures in animal models and human tissue samples. The treatment delivers a specific gene that produces dynorphin, modulating neural activity and dampening seizure spread.
A recent study published by Wake Forest Baptist Health suggests that the microbes living in our gut play a key role in childhood obesity. The review of existing studies reveals how a mother's health, diet, exercise level, and birth method can affect the risk of obesity in her children.
Researchers at the Allen Institute have mapped the mouse brain's neural connections, revealing an underlying hierarchy of brain circuitry. The study provides a detailed view of how neurons communicate with each other and offers insights into diseases such as Alzheimer's and schizophrenia.
Lithium-air batteries offer a maximum specific energy of 3,460 W h/kg, but scientists need to overcome obstacles such as unstable electrolytes and interference from air pollutants. The technology uses oxygen to oxidize a lithium-metal anode and could be powered by a plane's onboard air storage and filtration systems.
Researchers have found that fossil pollen can be preserved in floodplain soils, allowing scientists to reconstruct past climate dynamics and land use patterns. The study used soil properties such as organic matter concentration and carbon-to-nitrogen ratio to predict pollen abundance, providing a new tool for climate reconstruction.
Researchers will conduct baseline studies on stream morphology and aquatic habitats before bridge construction and develop predictive models for Texas Department of Transportation. They aim to determine the downstream ecological impacts of bridge construction on freshwater mussels and assess floodwater's force on typical bridges.
Researchers found that a pathogenic fungus alters the metabolism of its host algae, producing carbolines that benefit the fungus while harming the algae. The study sheds light on the complex interactions between microorganisms and their hosts in oceanic ecosystems.
In West Virginia, only 1.8 percent of students are identified as gifted, despite the state's rural communities having untapped talent. Researchers aim to develop universal screening norms and increase parent advocacy to boost access to gifted services for low-income students.
A study by Brigham and Women's Hospital found that irregular fluctuations in daily motor activity can predict increased risk of frailty, disability, and mortality in older adults. The researchers analyzed data from 1,275 participants and found that random activity fluctuations were associated with a 31% increase in frailty risk, 15-25%...
Two studies by ISGlobal found that the quality of green spaces influences physical activity, social contacts and emotional well-being. The presence of green space was associated with a higher frequency of physical activity, more time spent performing health-related activities, and increased social contacts with neighbours.
Researchers at Massachusetts General Hospital developed a new method to examine the activity of human hair follicles using magnetic fields. The technique measures electrical activity in individual study subjects and has shown promise as a biomarker for treating hair loss conditions like alopecia.
A study found that childhood thinking skills are associated with improved performance on cognitive tests at age 70, even after accounting for education level and socioeconomic status. Participants with amyloid-beta plaques in the brain scored lower on cognitive tests, but this was not linked to sex or other factors.
A study of pediatric major trauma cases found that nearly 3% of U.S. children who survive major trauma experience another sudden injury in the same year, with violence being a significant risk factor. Repeated injuries are more common among children from lower-income families and those with mental health issues.
Researchers discovered shared brain circuit abnormalities in patients with mood and anxiety disorders, enabling targeted interventions. These findings hold promise for improving outcomes for individuals with major depressive disorder, bipolar disorder, post-traumatic stress disorder, and anxiety disorders.
Research suggests that the prevalence of cannabis use disorder has decreased among frequent users between 2002-2016, with significant declines observed across all age groups. This decline may be attributed to changes in social attitudes and perceptions of risk associated with cannabis use, as well as increased legalization.
Researchers at University of Texas at Austin and University of Minnesota debunked the myth of a correlation between Super Bowls and sex trafficking, citing empirical evidence that shows no causal link. A study found that online ads for sex may temporarily increase during large public events, but this is not the same as trafficking.
Patients treated for breast cancer at a safety net hospital achieved comparable five-year survival outcomes to national averages, despite having more advanced disease and socioeconomic challenges. A multidisciplinary clinic streamlines diagnosis, treatment, and follow-up, resulting in high-quality clinical outcomes.
Brazilian researchers have discovered a new species of fungus gnat that emits blue light, which is the first record of such a species in the Neotropics. The larvae produce three lanterns and emit blue light, while adult insects do not.
Cornell researchers develop inexpensive, touch-sensitive soft robots to predict grape yield and detect fungal threats. The method uses machine learning to analyze plant growth patterns, allowing for early prediction and more time for planning.
Kaiser Permanente research identifies a national trend of increasing deaths due to heart failure among US seniors, with over 647,000 people dying from heart disease in 2017. The study highlights the importance of addressing heart health in older adults as the population continues to age and grow.
The LEGO Foundation has awarded a $3.2-million grant to Boston College's Research Program on Children and Adversity to expand its Sugira Muryango intervention for extreme poverty families in Rwanda. This will impact over 10,000 children and 14,300 parents, with the goal of empowering caregivers through playful parenting initiatives.
Researchers analyzed extensive video of Pollock at work to understand his technique, which avoided coiling instability through a combination of high hand speed and short paint height. This discovery challenges previous theories on the creation of his iconic paintings.
A genetic study on the critically endangered regent honeyeater found that while genetic diversity remains intact, habitat protection is key to saving the species from extinction. The researchers used DNA samples from museums and wild birds to compare genetic makeup before and after severe population decline.
Researchers developed a lab-on-a-chip device to observe thousands of individual cells infected with virus, providing new information on infection dynamics. The device allows for the simultaneous observation of multiple cells, enabling researchers to test antiviral compounds and understand their effects.
Researchers launch a beta website allowing users to review proposed research projects and predict outcomes, aiming to improve the rigor and credibility of social science research. The platform could help identify truly surprising results and gauge expert accuracy in certain areas.
The Society for Laboratory Automation and Screening (SLAS) has chosen 53 life sciences students from 12 countries to receive the SLAS Tony B. Academic Travel Award. The award winners will present their research at the SLAS 2020 International Conference and Exhibition in San Diego, CA, USA.
Researchers found that commensal papillomaviruses on human skin can induce immunity protecting against squamous cell carcinoma. The presence of these viruses in patients with suppressed immune systems was shown to reduce the risk of skin cancer, suggesting a novel method for prevention using a vaccine to boost the immune system.
A new study found that physicians who received gifts related to opioid medications were more likely to prescribe opioids the following year. The study also revealed significant variability in opioid prescribing across different medical specialties, with primary care physicians and psychiatrists being among those most likely to be in th...
A team of scientists found that two-thirds of the Earth's surface moves faster than the underlying mantle, with the surface dragging the interior. The study suggests that the balance of forces changes over geological time, especially for continents.
A study of nearly 1,000 mother-child pairs found an association between fetal exposure to acetaminophen and increased risk of childhood attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). The research used umbilical cord blood samples to investigate potential developmental effects.
A recent study by NYU College of Global Public Health found that construction workers are the most likely profession to misuse opioids and cocaine. The researchers analyzed data from over 293,000 participants and discovered a strong link between physical demands of construction work and substance use.