A new study reveals that Z-drugs are associated with adverse effects similar to benzodiazepines, particularly for people with dementia taking higher doses. The research recommends avoiding higher dose Z-drugs and instead considering non-pharmacological alternatives.
A multi-institution team identified the genetic mechanisms enabling the production of Victorin, a deadly toxin causing Victoria blight in oats. The study discovered that Victorin genes are scattered across repetitive regions in the pathogen genome, expanding the potential for small molecule discovery.
Researchers analyzed a massive dataset of seasonal events across the former Soviet Union and found that species' activities fail to keep up with their cues due to past evolution. Local adaptation patterns result in a massive imprint on nature's calendar, making geographic variation in seasonal timing more pronounced in spring and less ...
The Canadian Partnership for Research in Immunotherapy Manufacturing Excellence (CanPRIME) provides hands-on manufacturing training to develop novel biotherapeutics, including vaccines and therapies that incorporate viruses, cells, and genes. Nearly 50 individuals will be trained over five years.
Researchers at NASA's John H. Glenn Research Center use microgravity to study fire whirls, shedding light on ways fires burn without gravity and informing protective measures for astronauts. New computational fluid dynamics models improve predictions of wildfire behavior by accounting for varying fuel moisture content.
A study found that topography, rather than vegetation, is the main factor leading to genetic diversity of Bokermannohyla ibitiguara, a tree frog endemic to the Serra da Canastra mountain range. The flatter terrain allows for greater dispersal and increased genetic diversity.
A study of over 300,000 UK births found that many new mothers miss their scheduled postnatal check-ups, with younger women and those from deprived areas being the least likely to attend. This gap in care can have serious consequences for women's physical and mental health.
A University of Houston study analyzed sales data of restaurants in China before and during the pandemic, revealing revenue from delivery services increased by over 26%. Fine dining establishments saw a significant variation in financial performance, with discounts not effective in increasing sales.
Researchers have developed a new theory for observing the quantum vacuum, which could lead to new insights into black hole behavior. By using sound particles and ultra-cold atoms, they created a two-dimensional cloud where sound waves become audible to an accelerated observer in a silent phonon vacuum.
Scientists are studying the infrasound signatures of tornadoes to develop more accurate prediction and warning systems. Researchers have found that these vibrations can travel long distances quickly and through different media, potentially allowing for early detection of tornadoes from far away.
Researchers find molecular fossils extracted from 635-million-year-old rocks are not the earliest evidence of animals, but rather common algae. The discovery sheds light on the origin of animal ancestors and their abundance in ancient oceans.
Researchers at UT Austin created the smallest memory device yet, shrinking its cross-sectional area to a single square nanometer. Defects in materials unlock dense memory storage capabilities, paving the way for ultra-dense storage, neuromorphic computing systems, and more.
A recent study by Dr. Jeff Russell highlights the risks of concussions for performing artists, particularly stunt performers, who often go unnoticed in comparison to athletes. The research emphasizes the need for better treatment guidelines and healthcare resources for this segment of performers.
Researchers found significant differences in substance use, socioemotional health and academic achievement across Somali, Hmong and Latino youth. Acculturated individuals were more likely to engage in substance use and have lower academic achievement.
Researchers at MLU discovered that special activity trackers can accurately measure respiratory rates while sleeping, offering a new diagnostic tool. The study showed that minimal arm movements can provide more precise conclusions about breathing than standard ECGs.
Researchers found that the medicinal plant Lu Bei has evolved camouflage in response to human harvesting, changing color from brown to green depending on collection intensity. The study suggests that this adaptation may weaken the plant's attractiveness to pollinators.
Women continue to be underrepresented in math-intensive STEM fields due to country-specific differences in gender stereotypes, with the strongest stereotypes found in wealthy countries. Economic development and gender equality rights are associated with reshaping rather than suppressing these stereotypes.
A University of Stirling study found a decrease in self-reported sea turtle egg consumption and poaching of adult sea turtles after a community-based campaign. However, the increase in anti-poaching law enforcement may have impacted results.
Researchers study large-scale wind turbine design to overcome efficiency and cost challenges. Advanced computational methods reveal the physics of giant rotating machines, enabling better understanding of wind turbine wakes and interactions with the atmosphere.
The study found that molecular conformation affects charge carrier mobility and broadband emission in 2D organic-inorganic hybrid perovskites. The researchers discovered a strong correlation between the gauche defect, local chain distortion of organic cations and in-plane mobility reduction.
Researchers at TU Wien have developed a new method to produce short, intense infrared laser pulses using tailor-made quantum cascade lasers. The technology can be easily miniaturized, enabling compact measuring instruments for detecting specific molecules in gas samples.
Scientists warn that limited resources on the moon could lead to overcrowding and conflict as site selection and extraction become reality. A framework for managing these challenges already exists, drawing from analogs on Earth like common-pool resources.
A study by researchers at the University of Notre Dame found that global warming is likely to increase disease risk in animals, particularly those living in colder climates. The thermal mismatch hypothesis suggests that pathogens thrive in warmer temperatures, while cold-adapted animals struggle to cope with rising temperatures.
A study has found that middle-aged and older adults are at risk of contracting STIs due to negative attitudes and limited knowledge about their sexual health needs. The report's findings highlight four critical areas where interventions can address gaps in current healthcare provision: awareness, access, knowledge, and stigma.
Researchers at King's College London have discovered a way to change baby brain activity through associative learning, which could lead to innovative rehabilitation methods for infants with brain injuries. The study involved 24 infants who learned an association between sound and movement, resulting in altered brain activity.
Researchers discovered that severe infections disrupt the processes that form blood cells in mice, causing long-term damage. However, a hormone treatment and antioxidant may reduce this damage. The study found that this treatment can increase HSC function by up to tenfold.
The study successfully demonstrated an optimal entanglement collective measurement that reduces quantum backaction to zero in a two-qubit system under strongly coherent evolution. The experiment achieved high fidelity of 98.5% and marks a significant advancement in the field of quantum thermodynamics.
A study by German Primate Center found that coppery titi monkeys in Peru exhibit genetic monogamy, with none of the 18 offspring examined not sired by their social father. This suggests that mate choice is successful enough to outweigh potential genetic costs of infidelity.
A team of oceanographers from the University of Hawaii and colleagues discovered a massive aggregation of fish in the abyssal deep sea, with over 115 cutthroat eels recorded at one time. The finding provides evidence for an abyssal seamount effect, where these mountains can support much higher numbers of animals than surrounding habitats.
Researchers have developed a predictive model to guide plant breeders in selecting suitable corn varieties based on genomic analysis. The study focused on predicting eight corn traits using shoot apical meristem (SAM) analysis, achieving accuracy ranging from 37% to 57% across the eight traits studied.
Researchers have successfully bioprinted miniature human kidneys in a lab using cutting-edge technology. The study validates the use of 3D bioprinted human mini-kidneys for screening drug toxicity, paving the way for new treatments and potentially lab-grown transplants.
A study led by The Jackson Laboratory and University of Maine found that the expression of Dlgap2 is associated with memory loss in mice and risk for Alzheimer's dementia in humans. Dlgap2 influences the formation of dendritic spines on neurons, which can affect cognitive function.
Researchers found subglacial waters in Antarctica and Greenland have higher concentrations of essential trace elements, challenging scientists' understanding of the Earth's geochemical processes. These discoveries may significantly impact the development of healthy ecosystems and the ocean waters receiving ice sheet meltwater.
An international study found a genetic variant reducing leptin production increases obesity risk in young children of African ancestry. In contrast, adults with the same variant are not at higher risk, suggesting leptin plays a critical role in early weight regulation.
Researchers at NSLS-II are building a quantum-enhanced x-ray microscope to image biomolecules like never before, enabling superior resolution without sacrificing dose. The facility's ultrabright light will be harnessed through ghost imaging techniques to preserve sensitive samples.
A new algorithm developed by Rensselaer Polytechnic Institute uses chest CT images and non-imaging data to predict COVID-19 patient outcomes. The algorithm was tested on 295 patients from three hospitals and showed promising results in determining the need for ICU intervention.
A new study finds that atmospheric rivers in the Southern Hemisphere are shifting toward the South Pole, which could lead to increased rates of ice melt in Antarctica. The shift is driven by a combination of factors, including ozone depletion, greenhouse gas emissions, and natural variations in sea surface temperature.
Researchers exploring the nature of AI failures reveal 'adversarial examples' may not be intentional mistakes. Instead, they might be 'artifacts' created by interactions between network and data patterns. This rethink suggests that misfires could offer useful information if interpreted correctly.
A large long-term study found that hormonal contraceptives may lower the risk of severe asthma bouts in women of reproductive age. However, the protective effect is relatively small and does not include progestogen-only Pill.
Researchers developed an AI-powered method to detect Parkinson's disease from retinal images, identifying smaller blood vessels as key features. The approach is less costly and more accessible than traditional brain imaging techniques.
The Rappbode Reservoir in Germany is facing new challenges due to climate change, with projected temperature increases that could lead to significant changes in the reservoir's physical structure. This could result in increased oxygen demand, intensified nutrient dissolution, and algae growth, posing a risk to the drinking water supply.
Direct visualization of quantum dots in bilayer graphene reveals a broken rotational symmetry with three peaks instead of concentric rings. This discovery provides crucial information for developing quantum devices based on this system.
A new study by Boston Medical Center reveals that opioid overdose deaths involving multiple substances are more prevalent among youth than opioid-only deaths. Cocaine and other stimulants were found to be the most common substances involved in these deaths, contributing to a significant increase in rates between 2010 and 2018.
A new study by the University of Pennsylvania School of Nursing found that home health care significantly improved symptoms and functional outcomes for COVID-19 patients after hospital discharge. The study involved over 1,400 patients who received skilled nursing and physical therapy at home, resulting in a 94% improvement rate.
A new study published in Science reveals that more than 4,400 species are at risk due to excessive or insufficient fire activity. The research highlights the impact of climate change, land-use changes, and invasive species on fire regimes, threatening biodiversity hotspots worldwide.
Researchers at the University of Texas at Dallas are working on a new brain implant that aims to restore vision to people with blindness. The device uses small electrodes to stimulate neurons, producing phosphenes that can help individuals recognize objects and navigate their surroundings.
The new ViruSurf system facilitates rapid exploration of genomic data, enabling better understanding of viral mutation patterns. Researchers can now query when mutations started and how they spread globally.
Researchers have created simple and inexpensive ventilators and respiratory apparatuses to treat patients more effectively and prevent disease transmission in hospitals. The devices can be built at home, reducing the risk of infection for medical staff.
Researchers have identified the BICRA gene as a new disease gene involved in neurodevelopmental disorders. The study found that mutations in the BICRA gene can cause disease in humans and flies, and may provide new insights into how to develop individualized medical plans for patients with similar conditions.
Researchers found that people who move their mouse towards a safe option may be more risk-averse than they appear, while those who veer towards a risky option may be more open to risk. The study used mouse tracking to analyze participants' decision-making and found accurate predictions of future behavior.
A study of over 135,000 pediatric patients found that 4% tested positive for SARS-CoV-2, with severe disease seen in 7%, mostly among those with underlying medical conditions. Children from ethnic minorities and adolescents were more likely to test positive.
Researchers integrate nanodiamonds into nanophotonic circuits, controlling individual photons and spin states, enabling high-sensitivity magnetic field sensors and new applications in quantum technologies.
A new study from MIT finds that long periods of social isolation activate the brain's substantia nigra region in a way similar to food cravings. The researchers used an innovative isolation method to induce strong feelings of loneliness, and found that the resulting craving signal was correlated with self-reported levels of loneliness.
Research on strain engineering of 2D materials, including graphene and transition metal dichalcogenides, has shown promising results. The unique mechanical and optical properties of these materials make them suitable for optimizing device performance and enabling new photonic applications.
Scientists at ChristianaCare's Gene Editing Institute are developing a novel gene therapy for inherited blood disorders like sickle cell disease using CRISPR technology. The team aims to identify genetic variations that affect treatment efficacy and create a tailored approach for personalized medicine.
A new consortium, Accelerating Research and Innovation for Advanced Therapies (ARDAT), aims to develop standardized models for predicting ATMP immunogenicity in humans. The €25.5 million project will also build understanding of ATMP drug metabolism within a host.
A new imaging technology allows researchers to see multiple intracellular signals simultaneously, revealing their relationships and interactions. This breakthrough could illuminate complex processes like learning and memory, as well as diseases such as Alzheimer's and cancer.
A team of astrophysicists has created a complete family tree of the Milky Way, revealing a previously unknown galaxy collision that permanently altered its appearance. The researchers used advanced computer simulations and artificial intelligence to study the merger history of the galaxy.
Researchers found that Siberian primrose performed better in northern Norway than in southern Finland, indicating a lack of adaptation to global warming. Assisted migration and ex situ conservation are proposed solutions to help the species survive.
A mechanical engineer uses pancake batter to teach students about viscosity, while a group at ETH Zurich studies the stability of foam in beers and breads. The research reveals diverse mechanisms behind fluid dynamics, potentially leading to new materials and applications.