A study published in JCO Precision Oncology found that genetic testing can significantly improve patient safety by providing tailored doses of chemotherapy, reducing severe side effects. The test identifies variants in two genes that impact how the body processes chemotherapy drugs, allowing doctors to adjust doses and minimize harm.
The Barcelona CryoZoo has been awarded a competitive grant from Revive & Restore to derive and study stem cell lines from wild animal species. Researchers will use machine learning and artificial intelligence tools to identify critical gene networks needed for reprogramming cells from evolutionarily distant species.
Researchers at ICFO have created a single photon detection system that can operate in the mid-infrared range at relatively high temperatures. The system uses twisted 2D materials to detect long-wavelength single photons and exhibits bistability, allowing for extreme sensitivity to illumination.
The Hubble Space Telescope has captured the sharpest-ever picture of the interstellar comet 3I/ATLAS, allowing astronomers to estimate its size and physical properties. The comet's solid, icy nucleus is estimated to be between 1,000 feet and 3.5 miles across.
Optical vortices have been found to contain a complete skyrmionic texture when Maxwell's longitudinal field is retained. This discovery opens up new possibilities for high-dimensional OAM communication and topologically protected routing in planar photonics.
A team of scientists has successfully demonstrated a more practical and robust method for quantum key distribution, which could lead to secure and cost-effective communication networks worldwide. The breakthrough uses composable security and achieves a secure key rate using simple telecom hardware combined with digital postprocessing.
Researchers at ETH Zurich and TU Wien have successfully isolated rotational vibrations in nanoparticles, allowing for the extraction of energy in a quantum ground state even at room temperature. This breakthrough enables the study of quantum physics in objects that are significantly larger than atoms and molecules.
Researchers have discovered a potentially massive black hole, 36 billion solar masses, in the Cosmic Horseshoe galaxy. The discovery was made using a combination of gravitational lensing and stellar kinematics, allowing for more certainty about the mass of this black hole than previous measurements.
Researchers found that adding ethane to methanotrophs' core metabolism boosts polyhydroxybutyrate (PHB) synthesis and reduces methane consumption. The study sheds new light on methanotrophic metabolism in mixed-gas environments, offering possibilities for sustainable biopolymer production.
Researchers developed a strategy to predict multiple traits at once based on the whole genome, increasing predictive ability by 2-10 times. This method, called multi-trait genomic selection (MT-GS), combines genetic markers with known trait links for more accurate predictions, making it a promising tool for efficient and cost-effective...
A Houston Methodist research study reveals that 85% of astronauts on the International Space Station experienced at least one nasal or sinus issue, with 75% reporting nasal congestion. The study highlights the need for preventative measures and treatments tailored to space travel.
The "HippoBox" project aims to investigate neuroplastic changes in the hippocampus using brain organoids in real weightlessness. The research could provide new insights into cognitive health of space travelers and potential treatments for depression and dementia.
Researchers discover epicatechin gallate, a compound from maple, can prevent biofilm formation of Streptococcus mutans, causing dental caries. The compound may be used in safer alternative mouthwashes for young children.
The Department of Energy recognized Sandia's Mentor-Protégé Program as a model for mentor-protégé collaboration and innovation. Strategic Industry Inc., a veteran-owned small business, was named Protégé of the Year for its significant development through the program.
Researchers at MIT have developed a new microscope system that can visualize metabolic and neuronal activity in brain tissues with unprecedented depth and precision. The system uses sound waves to detect molecular activity, enabling the imaging of individual cells in dense brain tissue.
Researchers from Helmholtz-Zentrum Dresden-Rossendorf discovered how diatoms chemically interact with uranium, finding it bound both on the surface and within the algae. The team's findings provide initial insights into the chemical bonds formed and help understand the impact of uranium release on natural cycles.
Scientists at Goethe University Frankfurt have directly measured the correlated zero-point motion of a molecule's atoms for the first time, revealing complex patterns of vibrational modes. The experiment uses Coulomb Explosion Imaging to generate high-resolution images of the molecule's structure.
Nitisinone, a drug used to treat rare genetic disorders, has been shown to be mosquitocidal to several mosquito species, including those that transmit malaria and Zika viruses. The research demonstrates that the drug can kill mosquitoes through ingestion and surface contact, making it a potential tool in combating insecticide resistance.
Researchers developed an electrospun scaffold loaded with copper oxide to restore copper homeostasis and modulate inflammation in TBI. The study found significant reductions in neuronal pyroptosis, brain swelling, and improved motor and cognitive functions in animal models.
A new study by Max Planck Institute scientists reveals female mountain gorillas can win one in four conflicts and outrank non-alpha males. They also enjoy priority access to food resources over males they overpower, blurring the traditional male-dominated narrative.
Researchers developed pH-responsive graphene-based nanocarriers that can target cancer cells, achieving efficient and safe drug delivery. The material's surface charge adapted to the acidic tumor environment, allowing it to bind and enter cancer cells while avoiding healthy tissues.
City of Hope launches Phase 2 trial to test nonsurgical treatment strategy for rectal cancer, and a Phase 1 trial explores novel drug triapine for glioblastoma. A liquid biopsy shows promise for early detection of gastric cancer with high accuracy.
The article suggests a standards-based approach to governing emerging quantum technologies, drawing on existing frameworks like ISO 27001. This framework would oversee the design, implementation, and lifecycle of quantum technologies, addressing challenges like post-quantum cryptography.
An interstellar mission to test astrophysical black holes is proposed by Cosimo Bambi, harnessing nanocrafts and laser beams to gather data on nearby black holes. The mission aims to answer pressing questions in physics, including the nature of event horizons and general relativity.
Researchers propose a novel control scheme to address challenges in traditional backstepping control designs and event-triggered control. The scheme significantly reduces communication bandwidth usage, offering a new approach for efficient control of complex industrial systems.
Dr. Aruna Kilaru has been recognized as a Fellow of the American Society of Plant Biologists for her outstanding work in plant biology. Her research spans critical issues like food insecurity, biotechnology and clean energy, and she has secured over $3 million in grant funding.
DEZAWA MUSE Cells have the unique ability to focus on areas of damage and naturally differentiate into specific cells needed for repair. MUSECell Innovations is leading regenerative medicine with innovative therapies like DEZAWA GOLDEN IV, combining cells with advanced delivery technologies.
The new guidelines introduce a pivotal terminology shift, replacing NAFLD with MASLD and NASH with MASH. MASLD is now grouped under the umbrella of "steatotic liver disease" (SLD), along with alcohol-associated liver disease (ALD) and other causes.
Distinct immune pathways involving leukotrienes drive anaphylactic response in food allergies, with genetic variants influencing susceptibility. The drug Zileuton shows promise in blocking this life-threatening response.
Researchers improved WRF model precipitation simulation by optimizing Grell-Freitas cumulus scheme and Turbulent Orographic Form Drag scheme. This approach reduced overestimation of precipitation across the Tibetan Plateau.
A new network aims to improve malaria prevention among school-aged children in sub-Saharan Africa by uniting researchers, policymakers, and healthcare practitioners. The initiative will help fill knowledge gaps and develop guidance to support countries in addressing the burden of malaria in this age group.
Researchers developed a machine learning model to predict liquid crystalline polyimides with high thermal conductivity, achieving 96% accuracy. The model identified six promising candidates, which demonstrated up to 1.26 W/mK thermal conductivities, accelerating the development of efficient thermal materials.
Scientists at La Trobe University have developed a powerful new material that can conduct electricity as well as metals, making it ideal for wearable technologies like medical devices. The new technique uses hyaluronic acid to create a thin, durable film that is flexible and scalable.
Emerging evidence highlights the involvement of extracellular RNAs in the antiviral defense process, with microRNAs binding viral genomes via base-pairing interactions to inhibit expression. RNA immunity represents a complementary arm of the mammalian immune system, functionally independent of traditional protein-based defenses.
Researchers found that large language models like ChatGPT outperform humans in identifying neuromyths, but struggle to critically correct them. By prompting AI to explicitly correct false assumptions, error rates can be significantly reduced.
A national study calls for increased vaccine screening in emergency departments to address health inequities. The study found that nearly a third of the US population lacks primary care access and rarely receives vaccination screenings.
An international team of earth scientists proposes a new framework to understand the factors influencing CO2 removal, revealing their complex interactions and potential for enhanced weathering techniques. This integrated approach aims to enhance natural carbon storage, helping achieve Paris Agreement targets.
A major new textbook on autophagy is now available, encapsulating over 30 years of research in this growing field. The book, titled Autophagy – From Molecular Mechanisms to Flux Control in Health and Disease, aims to make the learning process easier for students and scientists alike.
A renowned climate scientist is sounding the alarm on extreme weather events in Asia, proposing an eight-point plan to address climate change. The plan focuses on investing in climate science, accelerating renewable energy, transforming urban mobility, and strengthening climate resilience.
A study from the University of Alberta reveals that water-soluble egg yolk hydrolysates can inhibit osteoclastogenesis and promote apoptosis in mature osteoclasts. The FC1 subfraction, extracted from an egg yolk fraction, demonstrated significant inhibitory effects on osteoclast formation.
Researchers developed an antibody transport vehicle targeting the transferrin receptor to improve anti-amyloid antibody delivery to the brain. The approach preserves key immune functions while offering a safer strategy for treating Alzheimer's disease, reducing side effects and increasing treatment efficacy.
Gordian Biotechnology, a therapeutics company, will sponsor ARDD 2025, showcasing its lead program for osteoarthritis and advancing targets using gene therapy. The company's discovery platform enables early evaluation of therapeutic candidates in complex disease models.
A multi-year clinical research study in US children documents the rebound of endemic respiratory viruses after the COVID-19 pandemic. The study shows that non-pharmaceutical interventions decreased circulation rates of common respiratory pathogens in children, enabling more accurate predictions for future outbreaks.
Researchers analyzed centromeres in onion, garlic, and Welsh onion using CENH3-targeted antibody to map centromere regions. They found significant variations in size and position/mobility between species, challenging the static view of centromeres.
Rejuve.Bio will sponsor ARDD 2025, a premier conference on aging research, to advance drug discovery for healthy longevity. The event brings together world-class researchers, clinicians, and innovators to discuss cutting-edge solutions for age-related diseases.
The study analyzed the northbound migration of northern fur seals, revealing that they concentrate foraging activity along continental shelf-breaks and near anticyclonic eddies. The findings provide new insights into the seals' response to oceanographic conditions and highlight the importance of long-term monitoring in understanding th...
Scientists create a way to eliminate harmful bacteria from the gut to prevent infections by using beneficial bacteria as an alternative. The approach has shown promising results in laboratory tests and mouse models.
Researchers from Yale University have found that adding crushed calcium carbonate to agricultural fields can remove tons of carbon dioxide from the atmosphere while improving crop yields. This natural carbon removal process has the potential to support farm productivity and help mitigate climate change.
Researchers develop hybrid energy storage system to address solar intermittency challenges. The dual-level design combines lithium-ion batteries with supercapacitors to extend battery lifespan and optimize costs.
NADMED will showcase its advanced tests at ARDD 2025, highlighting the role of NAD in metabolism, cellular repair, and longevity. The company's technology empowers scientists and clinicians with reliable data to develop targeted therapies and interventions.
Exosomes from tumors can promote cancer cell proliferation and angiogenesis, while also suppressing immune responses by delivering immunoinhibitory ligands. The review highlights the potential of exosome-based therapeutics to restore antitumor immunity.
Researchers at Rice University developed a mechanistic model to simulate how oxidants and pollutants move through and react inside catalytic membranes. The framework identifies the ideal range for catalyst loading and introduces new performance metrics to improve membrane design.
Researchers developed a novel carbon precursor pre-coordination strategy to precisely regulate the coordination environment of metal atoms in single-atom nanozymes. The approach successfully synthesized CuMn-CDs with exceptional antioxidant capacity and efficiency, even at low concentrations.
An international research team has identified epigenetic biomarkers that can predict which individuals with type 2 diabetes are at risk of cardiovascular disease. The study used DNA methylation as a way to identify these biomarkers in blood, and found over 400 sites with altered DNA methylation.
Emerging evidence supports Mediterranean Diet and plant-based patterns in reducing endometrial cancer risk. The review also highlights the importance of physical activity, insulin sensitivity, and genetic stratification in personalized prevention frameworks.
A new optoelectronic nose design detects deadly gases by using microscopic silica particles coated with dyes that change color intensity in the presence of specific molecules. The sensors achieved high accuracy rates, including 99% for identifying chemical threats and 96% for measuring gas concentrations.
A modeling study finds that COVID-19 vaccination is more cost-effective for individuals aged 65 and above, with favorable results across different parameter input scenarios. The study's findings support the Advisory Committee on Immunization Practices' decision to recommend vaccination with the 2023-2024 mRNA vaccines.
Researchers discovered that licorice extract significantly curbs spore growth of P. bifermentans in RTE chicken breast, preserving meat quality and shelf life. The study's findings mark a significant step toward replacing synthetic preservatives with natural solutions.
Researchers have discovered a key protein, RTMP1, guiding the formation of chitons' ultra-hard iron-based teeth. This finding offers new insights into biomineralization and potential inspiration for novel materials design.
A University of Toronto study finds that global warming may increase the risk of invasive ant species by enabling them to expand into outdoor environments. Researchers warn that some indoor-only ant species have the potential to cause significant damage if they become established outdoors.