Professor Yazaki-Sugiyama's research on neural mechanisms of vocal learning during critical periods has significantly advanced our understanding of brain learning mechanisms. She is recognized for her original and outstanding work, which has revealed key findings on neural plasticity.
A team of researchers from Chung-Ang University has developed an innovative air filter that mimics the way mucus-coated nasal hairs trap particles, achieving remarkable filtration efficiency. The particle-removing oil-coated (PRO) filter is a significant leap forward in air purification, offering improved performance and sustainability.
A new study finds that most Americans (2/3) want a more ethnically diverse society than the current one, while over half desire greater religious diversity. Even among white Christian Americans, there is a majority in favor of increased diversity.
Researchers at Shibaura Institute of Technology have developed a scalable and safer method to generate hydrogen fluoride, eliminating the need for pressurized HF gas and corrosive liquid reagents. The new fluorinating complexes can be used for pharmaceuticals, functional materials, and molecular probes.
A new analysis of a 500 million-year-old fossil suggests that arachnids, including spiders and scorpions, evolved in the ocean before adapting to land. The discovery was made by studying the brain and nervous system of an ancient marine arthropod called Mollisonia symmetrica.
A new book introduces a structure that balances efficiency and fairness in optimization models, examining real-world effects of different approaches. It suggests that truly optimal results are fair ones, promoting informed and ethical choices in algorithm-driven world.
CORNETO enables researchers to extract molecular networks by combining experimental data with prior biological knowledge, helping to better understand cell health and disease mechanisms. The tool identifies shared pathways and patient-specific differences, a step toward personalised treatment strategies.
A recent AI-powered study sheds light on the genetic origins of Papua New Guineans, finding a close relationship with other Asian populations. The research suggests that Papua New Guineans share a common ancestry from the 'Out of Africa' event, contrary to earlier theories.
The study reveals that four units of ZapA protein form an asymmetric ladder-like structure with FtsZ protofilaments, impacting the alignment of the Z-ring. The interaction between ZapA and FtsZ is dynamic, with cooperative binding and structural alterations, enabling the maintenance of FtsZ mobility.
Researchers found that repeated tickling increases oxytocin receptor expression in a rat brain region, mediating social bond formation across species. Pleasant tactile stimulation drives affinity-like behavior, indicating the formation of social bonds.
Afro-descendant peoples in four Amazon countries show remarkable achievements in environmental stewardship, according to new research. Their lands significantly exceeded the norm for conservation value, with 56% being top 5% globally for biodiversity.
A study published in Addiction found that nearly half of drug-caused deaths among healthcare workers involved hospital-only drugs. Opioids were the most frequently involved substance, followed by benzodiazepines, and anaesthetists were disproportionately represented in these deaths.
The CHARA Array has enabled groundbreaking discoveries about stars, including the massive star Regulus and binary star systems. With new capabilities, the array will continue to reveal secrets about stars, planetary systems, and distant supermassive black holes.
The 2025 Critical Path Institute Global Impact Conference will bring together industry, regulatory agencies, academia, and patient advocacy groups to discuss pressing challenges in drug development. The event aims to foster cross-sector collaboration to advance medical innovation and improve treatment outcomes for patients.
Researchers developed a new 3D tissue model to understand and treat fibrosis, a disease that causes scarring in organs like lungs and kidneys. The model replicates the complexities of real disease and preserves natural cell diversity.
A groundbreaking study published in Science Signaling has identified protein tyrosine phosphatase PTP1B as a key driver of maladaptive cardiac metabolism and dysfunction under dietary stress. Mice lacking PTP1B in cardiomyocytes were resistant to harmful changes, highlighting the enzyme's role in heart disease progression.
Research finds women politicians face harsher judgments when deviating from party expectations or policy stances. Voters scrutinize women candidates more intensely, especially when they diverge from party views, leading to greater uncertainty and skepticism.
Researchers at Oregon State University report a remarkable case of ecological restoration in Yellowstone National Park. The reintroduction of wolves has initiated a trophic cascade that reduced elk populations and allowed aspen trees to begin recovering, with nearly 80% of the 87 surveyed stands showing signs of growth.
Researchers from RIKEN have discovered that Japanese people's responses to alcohol can be divided into three clear clusters based on genetic analysis and experiments. These clusters are associated with specific combinations of gene variations, including ALDH2 and ADH1B, which can help identify individuals at risk for alcohol-related di...
Researchers at MURR have optimized Terbium-161 for radiopharmaceutical use, enabling targeted destruction of cancer cells with high-energy electrons. The breakthrough could add extra therapeutic effectiveness to existing treatments without requiring new drug development.
Advanced membranes via precise ion-selective nanochannels slash crossover rates, cut costs, and sustain cycle life. Lab-scale cells employing SPEEK/lignin composites achieve high coulombic efficiency and energy efficiency, outperforming commercial Nafion.
Researchers developed a new method for building powerful, compact energy storage devices using thin-film supercapacitors without metal parts. The device can output 200 volts, equivalent to powering 100 LEDs for 30 seconds or a 3-watt bulb for 7 seconds.
A new study by NYU Langone Health researchers found that the shutdown of a significant fossil fuel pollution source near Pittsburgh, PA resulted in immediate improvements in respiratory health. Respiratory related emergency visits decreased by about 20% within weeks after the plant's closure.
Researchers at Peking University have discovered a key mechanism governing proton storage and transport in aqueous batteries, enabling ultra-fast charging and higher capacity. By engineering hydrogen-bond networks, they propose three strategies to optimize battery performance, advancing next-generation proton-based aqueous batteries
A recent study maps how metformin modulates metabolism and protein expression across different zones of the diabetic kidney, offering key insight into its molecular mechanisms and providing a new framework for region-targeted therapy in diabetic nephropathy.
Researchers from The University of Osaka develop a new program to calculate the spin accumulation coefficient, providing a definitive measure of the spin Hall effect and overcoming ambiguities. This advancement enables accurate predictions for real materials, accelerating the development of advanced spintronic technologies.
A study of 22 million urgent care visits found 12.4% of patients received antibiotics, 9.1% glucocorticoids, and 1.3% opioids for generally inappropriate diagnoses. The trends highlight the need for improved clinician knowledge, patient demand, and decision support.
Researchers at Pusan National University developed a new Bayesian calibration framework to optimize digital twin models of automated material handling systems. The framework improves prediction accuracy by accounting for parameter uncertainty and discrepancy, enabling effective calibration with scarce field data.
Researchers discovered that approximately 436-million-year-old brachiopods formed a non-random, checkerboard-like pattern due to their tiny setae, which allowed them to maintain optimal spacing. This study provides rare evidence of ancient communities being shaped by biological interactions.
Conventional dendritic cells have been found to originate from both myeloid and lymphoid progenitors, revealing their unique functions and developmental pathways. These lymphoid-derived cDCs exhibit potent functions in immune suppression and allergy induction, and follow diverse developmental pathways.
The lab utilizes AI to automate and accelerate nuclear license applications, reducing review times by approximately 90% compared to traditional methods. This innovation aims to improve the efficiency of the licensing process while maintaining safety standards.
The annual UK cost of PTSD is estimated to top £40 billion, with direct costs averaging £1,118 per patient and indirect costs ranging from £11,373 to £16,797. The condition's economic burden is likely higher due to unmeasured costs such as stigma and discrimination.
A study by University of Notre Dame researchers found that almost a third of reusable menstrual products contain PFAS, despite being marketed as eco-friendly. The presence of these toxic fluorinated compounds poses risks to both users and the environment when disposed of.
A study documents elite-level strength training during active breast cancer treatment, showing rare retention of squat strength despite chemotherapy. LaShae Rolle, a competitive powerlifter and breast cancer survivor, completed the first-of-its-kind study, demonstrating the feasibility of high-intensity training when carefully managed.
A recent study found that Chinese obese individuals can maintain significant weight loss even after stopping tirzepatide. The study showed an average weight loss of 8.7% to 10.6% compared to baseline, with improved cardiometabolic markers. These findings support the long-term efficacy of tirzepatide in managing obesity.
A study published in Journal of the Mechanical Behavior of Biomedical Materials found that wrinkled skin is caused by its tendency to buckle under pressure due to age-related changes in its mechanical properties. As people age, their skin becomes more prone to wrinkles as it stretches and contracts in different directions.
A new study at Baylor College of Medicine reveals that disordered regions of proteins involved in gene regulation interact with structured beta-catenin to carry out gene activation. This discovery challenges the traditional view of disorder in biology, suggesting that interactions between disordered molecules and structured proteins gi...
A team of researchers has discovered a fifth planet in the L 98-59 planetary system, confirming its habitable zone and potential for liquid water. The planets' sizes and masses have been determined with unprecedented precision using data from space telescopes and high-precision instruments.
A study published in Frontiers in Veterinary Science found that Elenagen significantly reduced chronic osteoarthritis pain scores in dogs, achieving a 90% success rate. The therapy works by reprogramming aged or dysfunctional mesenchymal stem cells, which then produce anti-inflammatory signals and restore their regenerative capacity.
Researchers created a highly textured Zn surface by introducing benzyltriethylammonium chloride (TEBAC) and selectively removing its counter-ion, achieving unprecedented stability and durability. The optimized electrolyte delivered 9000 hours of dendrite-free cycling in coin cells.
Researchers at Stanford Medicine have developed an antibody treatment that eliminates the need for toxic busulfan chemotherapy or radiation in stem cell transplants, making it possible to treat patients with Fanconi anemia and other genetic diseases. The new approach has shown exceptional outcomes, enabling patients to complete two yea...
Researchers developed a new framework to compare 15 different mitigation measures on the Gold Coast, revealing that a combination of strategies is most effective at reducing shark bites. The study found that non-lethal real-time shark alerts and traditional strategies like SMART drumlines are key to reducing risk.
Researchers have identified CDX1 and CDX2 as key molecules that counteract β-catenin and suppress stemness in colon cancer. Deletion or overexpression of these proteins increased tumor aggressiveness and expression of cancer stemness-related genes, suggesting a potential therapeutic target.
Researchers find that albumin triggers a shift in fungal behavior, causing previously non-harmful Candida strains to grow strongly and release toxic compounds.
Researchers developed a proof-of-concept device to detect HMGB1 protein in menstrual blood, showing five times more sensitivity than existing laboratory tests. The test can detect low concentrations of the biomarker, enabling early detection and intervention for endometriosis patients.
A new study from Indiana University and Notre Dame researchers finds PFAS in nearly 30% of tested reusable feminine hygiene products. The presence of these chemicals has raised concerns about safety and transparency, particularly for adolescents and young women who use these products.
Researchers at Tohoku University have uncovered key principles that could advance sustainable ammonia production by electrochemically converting nitrate waste. Pyrrolic-coordinated M-N-C catalysts achieve higher turnover frequencies for ammonia production, and the adsorption of nitrate is the rate-determining step in this reaction.
Researchers conducted the world's biggest bird survey in Colombia, recording 971 species and finding that clearing rainforest for cattle pasture causes a 60% greater biodiversity loss than previously thought. The study highlights the need for policymakers to consider the larger-scale impact of deforestation on biodiversity.
Researchers found that astrocytes maintain optimal levels of GABA to enable neural groups to process visual information efficiently. Knocking out Gat3 in mice impaired neuron coordination and reduced ensemble activity, highlighting the importance of astrocytic regulation.
A University of Kansas study found that people rate corporate crises messages written by humans as more credible and trustworthy, regardless of the approach taken. However, the approach itself didn't vary between participants who read human or AI-written content.
A new UT Arlington study explores how sleep deprivation affects police performance and suggests tailored sleep interventions may help. Officers reported getting seven hours or less of sleep per night due to shift work, job pressure, and emotional fatigue.
A conclave of paleontologists, data scientists, and journal editors will meet in Kansas to improve how data is shared among professionals and beyond. The event aims to align paleontological data with FAIR practices, making it easier for researchers to access and reuse.
Researchers at UC San Diego School of Medicine have discovered a link between stress and inflammation and pancreatic ductal adenocarcinoma (PDAC), a type of aggressive and lethal cancer. The findings could lead to the detection of PDAC before it becomes life-threatening, enabling early screening tools for precision medicine.
SwRI's award-winning NEXTCAR project successfully completed its 8-year-long connected and automated vehicle technology project. The completed SwRI NEXTCAR vehicle demonstrated up to 30% energy savings compared to traditional hybrid vehicles.
Researchers developed an 'aging clock' that can assess the biological age of brain cells and identify potential rejuvenating interventions. The study found 453 unique compounds with therapeutic potential, some of which are known to extend lifespan in animal models.
Researchers discovered a new pathway to boost immunity against parasitic infections, suggesting that NSAIDs like ibuprofen could be repurposed as anti-parasitic treatments. Gasdermin C plays a crucial role in this process, targeting and penetrating Rab7-positive vesicles to reduce prostaglandin d2 levels.
Researchers discovered that a subtle shift in gene activity rhythms at higher temperatures, known as waveform distortion, helps maintain the body's 24-hour cycle. This process also influences synchronization with day-night cycles and environmental cues.
A recent study by Florida Atlantic University found that US adolescents with cannabis use disorder have low treatment completion rates, ranging from 34.2% to 33.8%. The most common reasons for not completing treatment were dropping out, transferring facilities, and being terminated. Adolescents who began using cannabis at a younger age...
Researchers have successfully reconstituted mouse egg cell development from embryonic stem cells entirely in vitro, without ovarian support cells. This new method enables detailed analysis of molecular mechanisms and has important implications for human reproductive biology and fertility preservation.
A recent study published in Nature Metabolism found that patients with type 2 diabetes have accumulated misfolded proteins in their mitochondria, which can lead to cell death. The researchers hope that targeting the protein-folding mechanism could be a new avenue for therapy.