A new study found that less than 5% of children admitted to hospital with suspected sepsis met the Phoenix Sepsis Score, highlighting the need for more accurate measures to diagnose sepsis in children. The research also showed that the current clinical tool failed to detect cases early and underestimated the overall burden of disease.
Researchers discovered that statins selectively modulate key components of the Wnt/β-catenin signaling pathway, leading to lower levels of tumor-promoting proteins and cancer-suppressing cellular behaviors. Statins downregulate SATB1 while increasing SATB2, making cancer cells less able to grow and spread.
Scientists have identified a reliable method to achieve stabilization in compressed earth blocks using recycled glass particles and lime. Testing showed that a mix of 10% lime and 10% recycled glass produced the strongest blocks with no cracking under intense pressure.
Researchers developed a smart neural network model that combines CNNs and RNNs to predict multicolor soliton evolution, surpassing limitations of standard frameworks. The dual-channel system accurately tracks changes in energy, wavelength, and phase with remarkable accuracy.
A 21-day study found that restricting food variety triggers unique shifts in individual gut microbiomes, contradicting the assumption of uniform microbial outcomes. The results suggest personalized nutrition approaches are essential for achieving targeted microbiome modulation.
Researchers at UBC Okanagan discover that quantum Coulombic interactions play a key role in controlling free radicals, essential molecules for life. This finding has significant implications for the design of drugs and enzymes.
Curtin University researchers have detected significant Starlink satellite interference with radio astronomy observations, affecting up to 30% of images. The study highlights the need for regulatory improvements to minimize the impact of satellite technology on research.
Researchers used mathematical modelling to explain why babies nap on some days but not others, and how older people wake up earlier. The study showed that the 2PM model reflects brain activity as people switch between sleep and wakefulness, offering new insights into sleep patterns and potential solutions.
Researchers created a new type of cellulose-based plastic that displays structural color without dyes or pigments. The plastic is comparable in strength to traditional plastics but made from natural biodegradable ingredients, and it can be easily recycled using water.
A new breath test has been developed to detect blood cancers, showing promise for early diagnosis and treatment monitoring. The test uses exhaled breath analysis to identify molecules produced by cancer cells, potentially providing a quick and affordable diagnostic tool for areas with limited access to specialist equipment.
A new study by Macquarie University researchers found that adding colour to concrete panels increased marine biodiversity in Sydney Harbour. The team discovered that red panels supported communities distinct from other coloured panels, attracting higher numbers of green algae and barnacles.
Climate models project an accelerating increase in heatwave duration due to global warming, with each additional increment of warming causing larger increases in long heat waves. As temperatures rise, the typical length of heatwaves will also increase, posing significant impacts on humans, livestock, and ecosystems.
Research combines AI-generated disinformation with the repetitive truth effect to create persuasive content. A study found that while neither tactic convinced participants of conspiracy theories, AI-generated disinformation increased perceived consensus among both parties.
Researchers used an experimental technique called annealing to rescue a damaged camera on NASA's Juno spacecraft, offering lessons for other space systems that experience high radiation.
Researchers used synthetic STARR-seq to quantify the effects of single-nucleotide substitutions on ABRE activity. Alterations in the ACGT-core sequence had a significant impact on ABRE activity compared to changes in the flanking region.
A research team at Peking University has developed the first sort-in-memory hardware system tailored for complex, nonlinear sorting tasks. The system eliminates the need for comparators and introduces a novel Digit Read mechanism, along with a new algorithm and hardware design that reimagines how sorting can be performed within memory.
A new route of delivering gene therapy is being explored, potentially reducing invasiveness and increasing accessibility. Researchers will test a novel approach on non-human primates, aiming to expand access to office-based treatments.
A recent study found that behavioral flexibility is related to foraging breadth, not social or habitat use behaviors, in great-tailed grackles rapidly expanding their geographic range. The researchers discovered that flexible individuals switched between different food types more often in the wild.
City of Hope research demonstrates a new drug combination that slows advanced prostate cancer growth without improving overall survival. A novel AI conversation tool helps scientists uncover gene-disease connections without programming expertise.
A new study by Australian National University tracked wild guineafowl in Kenya and found that initiating movements led to high heart rates. The researchers also discovered that experiencing the minority resulted in a substantial physiological cost, including increased stress.
A recent consensus statement by radiologists aims to standardize the management of post-COVID patients with lung abnormalities. Up to 50% of hospitalized COVID-19 patients develop persistent or progressive respiratory symptoms and lung changes on chest CT scans, but these often stabilize or regress over time.
The Sustainability Accelerator at Stanford University has selected 41 new projects spanning biology, agriculture, electricity, industry, and water, addressing key climate vulnerabilities. The projects aim to drive implementation of sustainability challenges and create an ecosystem for impact.
The Digital Science relaunches its Scientometric Researcher Access to Data (SRAD) program, offering non-commercial scientometric studies free access to Altmetric and Dimensions data. The expanded program also provides access to Dimensions on BigQuery, enabling researchers to answer complex questions with big data.
A new study from the University of Notre Dame found that how healthcare providers describe babies during ultrasounds impacts parent perceptions and can influence a child's future behavior. Positive descriptions are associated with fewer behavioral difficulties in toddlers, while negative descriptions lead to greater challenges.
The International radiology consensus outlines best practices for post-COVID CT imaging, including standardized terminology and low-dose protocols. The guidelines aim to standardize the indications for chest CT and improve patient management.
Farms' economic resilience relies on a balance between stability and flexibility, with factors like payments and land ownership affecting stability and ecological conversion improving flexibility. This balance is crucial for farms to cope with external shocks and maintain production over time.
Researchers found that radiation plus immunotherapy induces a systemic anti-tumor immune response in non-small cell lung cancer, even in tumors that do not typically respond to immunotherapy. The combination therapy improved clinical response in patients whose tumors harbor features of immunotherapy resistance.
A new breeding concept for wheat aims to increase resilience to climate change by utilizing the microbiome. Researchers have identified varieties that produce natural nitrification inhibitors, which help control soil nitrification processes.
Researchers identified counties with vulnerable populations susceptible to longer-term power outages in the five-state region. Findings showed that hurricanes/tropical storms and heat waves were associated with the longest power outages, clustering in coastal and riverside counties.
New experimental techniques can measure intense magnetic fields generated in heavy-ion collisions, shedding light on fundamental physics and the early universe. By studying magnetic field evolution over time, researchers can gain insights into QGP behavior and its effects on particles.
A study analyzed social determinants' impact on mental health, identifying variables that predict problems, such as physical health, loneliness, and satisfaction. Implementing policies like financial stability, local community engagement, and volunteering may reduce mental illness rates by up to 3 percentage points.
A recent study published in Nature Communications found that the Covid-19 pandemic accelerated brain health decline, particularly among older individuals, men, and those from disadvantaged backgrounds. Brain scans revealed faster brain aging rates among those who lived through the pandemic, even if they were not infected.
A French-language study found that gender-fair job titles do not influence adolescents' reported career interest or sense of belonging in nursing, surgery, and clinical psychology. The study suggests that more comprehensive strategies are needed to counter deeply rooted gendered expectations.
By reprogramming chromatin to prevent cancer cells from adapting to evade treatment, researchers have doubled chemotherapy effectiveness in animal experiments. This approach restores cellular memory, making existing drugs more effective against cancer.
Researchers at UniSA propose a predictive analytics approach to identify high-risk areas before damage occurs, reducing pipe blockages and environmental contamination. The study suggests that traditional removal methods are not effective and can cause more harm.
A Rutgers University study found that exposure to green spaces during critical periods of early childhood development is associated with a reduced risk of neurodevelopmental disorders, including ADHD and autism spectrum disorder. Higher levels of green space exposure were linked to lower risks across different exposure windows.
Researchers found that speakers from different cultures convey emotions differently when complaining. Complainers use specific vocal expressions to convey negativity, with Québécois sounding more angry and French speakers sounding sadder. The study highlights the importance of tone of voice in social interactions and may have implicati...
Scientists at SwRI conducted lab experiments to explain the mysterious distribution of hydrogen peroxide on Jupiter's icy moon Europa. The research found that trace amounts of CO2 in water ice can enhance hydrogen peroxide production, shedding light on the moon's habitability and chemical cycles.
The Amazon has experienced a 163% increase in degradation and a 54% decrease in deforestation between 2022 and 2024. This 'negative balance' of biome protection threatens Brazil's international climate commitments, particularly its target to reduce greenhouse gas emissions by 59-67% by 2035.
Researchers have developed a novel catalytic system that enhances hydrogen oxidation reaction efficiency, paving the way for more efficient and durable anion exchange membrane fuel cells. The system balances hydrogen adsorption binding energy and hydroxyl adsorption energy, improving overall efficiency.
A Cornell University study found that entertainment agencies' status significantly impacts K-pop groups' style and music genre changes. Female groups face constraints due to societal expectations, whereas male groups have more flexibility in concept transformations.
Researchers developed the Su-Schrieffer-Heeger-Hubbard model, integrating electron-phonon coupling with Hubbard interactions to explain d-wave high-Tc superconductivity. The study reveals intricate competition among s-wave and d-wave superconductivities and stripe charge-density order.
Researchers propose adaptations to overcome barriers to the implementation of autonomous AI agents in healthcare, including extending enforcement discretion policies and developing voluntary alternative pathways. Long-term solutions include regulating AI agents like medical professionals, with structured training processes for autonomy.
A novel strategy for modulating crystalline-amorphous composites and electronic structures has been developed to enhance the hydrogen evolution reaction. The NiMo-NiMoO x electrocatalyst exhibits remarkable HER catalytic properties and durability, requiring a low overpotential of 30 mV at high current density.
Researchers at Carnegie Mellon University analyze historical U.S. carbon emissions trends, identifying factors that contributed to changes and offering lessons for developing countries. The study suggests that investing in efficient technologies and avoiding overreliance on coal can help avoid pitfalls encountered by the United States.
Researchers identify two human brain genes that contribute to brain size and synapse signaling in zebrafish, providing a roadmap for discovering more genes. The study's findings have significant implications for understanding language disorders and autism.
The DFUN-KDF framework uses federated knowledge distillation to enable UAVs to extract information from embedded data and update their local models, reducing energy consumption and improving adaptability. The framework's filtering mechanism eliminates biased embeddings, ensuring the stability and reliability of the system.
A new genetic test can predict adulthood obesity in early childhood, allowing for targeted preventative strategies. The test was developed using data from over five million people and found to be twice as effective as previous tests at predicting obesity risk.
Dr. Machado brings scientific expertise, clinical leadership, and mentorship to the Department of Medicine at UMSOM. He will advance research impact, enhance clinical excellence, and shape the future of academic medicine.
Researchers developed a chemical probe that binds to damaged mitochondrial DNA, blocking enzymatic processes that lead to its degradation. This approach lessens mtDNA loss, preserving energy production in vulnerable tissues. The new molecule successfully reduced inflammation and maintained functional DNA despite chemical tagging.
Researchers from Sapiens Labs created two ongoing data acquisition programs in India and Tanzania to collect large-scale, high-quality neuroimaging data. The programs have collected data from over 7,900 participants with comparable data quality to lab settings and lower costs.
A large Danish study shows that children with a high genetic risk for ADHD are more likely to experience severe neglect and childhood maltreatment. This risk is also influenced by parental mental illness, with girls generally exposed to more maltreatment than boys.
A recent study by Technion researchers discovered that soft drink consumption alters the DNA of gut bacteria, affecting the host's immune system. The effects are reversible, and the study highlights the importance of studying nutrition's impact on the microbiome.
Astronomers have detected a newborn planet in action, carving out an intricate pattern in the gas and dust surrounding its young host star. The planet candidate is estimated to be twice the size of Jupiter and has been observed shaping its surroundings within the protoplanetary disc as it grows into a fully formed planet.
A new study found that long COVID patients with abnormal cardiopulmonary PET/MR findings are at a higher risk of developing heart and lung diseases. The study included 98 patients with persistent cardiopulmonary symptoms after initial COVID infection and showed significant abnormalities in both PET/MRI and dual-energy CT scans.
New research reveals that body size and caste in ants are coupled, with genetics determining the threshold for becoming a queen. Genes influence size and modify the size at which queen-like traits emerge, affecting the probability of becoming a queen.
The Gemini North telescope has detected the long-predicted companion star of Betelgeuse for the first time. The companion star is six magnitudes fainter than Betelgeuse and has an estimated mass of around 1.5 times that of the Sun, confirming the presence of a stellar companion orbiting the red supergiant.
A combination of two approved cancer medications may slow or reverse Alzheimer's symptoms by reversing gene expression changes in neurons and brain cells. Researchers analyzed public data from deceased donors and found a link between these drugs and reduced risk of developing the disease.
Researchers found that ribose binds to phosphate more quickly and effectively than other sugar molecules, which could have helped select it for inclusion in RNA development. The study also showed that ribose produces a five-member ring form, similar to the forms seen in RNA and DNA today.
A new study led by Mount Sinai researchers has identified distinct biological signatures in patients with mild Crohn's disease, which may help avoid overtreatment and guide more personalized care. The findings suggest that these biomarkers can distinguish mild disease from more aggressive forms, potentially allowing for safer treatment...