A significant increase in childhood contact allergies has been observed in Finland over the past two decades, with a notable rise in allergic reactions to cosmetics and adhesives. The study found that young people are exposed to a range of allergens through their daily use of face masks, lip gloss, and other cosmetic products.
A recent study reveals ADAMTS9-AS2/let-7a-5p axis inhibits the Warburg effect and OSCC progression, suggesting a promising therapeutic target for treatment. The study highlights the importance of metabolic reprogramming in OSCC.
A team of experts envisions a path toward a carbon-neutral agricultural future by expanding policies designed to promote low-carbon biofuels. Climate-smart practices could reduce carbon emissions by 4-8 billion tonnes per year, according to studies.
A new method called ISM-FLUX streamlines MINFLUX by using a 5x5 SPAD array detector to capture spatiotemporal information from fluorescence photons, allowing for precise localization over larger areas without losing accuracy. This innovation enables faster and more user-friendly molecular-scale imaging in biology.
Researchers identified peptidoglycan hydrolases in archaea that kill bacteria, highlighting the importance of surveying diverse microbes to discover new antimicrobials. These proteins were found in 5% of surveyed archaeal species and show promise as novel antibacterial compounds.
Researchers developed a two-phase simulation model incorporating air-water interactions, representing eddies and aerosols more realistically. The hybrid method balances computing power and precision, conserving resources in less active areas.
PLOS Biology joins forces with MetaROR to enhance the peer-review process, utilizing pre-existing reviewer reports to streamline publication practices. This collaboration aims to promote open science and accelerate meaningful change in research publishing.
Early-life changes in fAD brain cells have been identified using stem cell-derived brain organoids, revealing key features of Alzheimer's disease. Treatment with Thymosin beta 4 has shown promise in reversing AD-specific changes.
Glacier-caused flooding is an annual threat in Juneau, with record-breaking floods over the past two years impacting hundreds of homes. The USGS provides real-time monitoring data to help emergency managers make informed decisions about evacuations and road closures.
Scientists developed a new 4D optical coherence tomography technique that measures airway wall elasticity in under 42 seconds, enabling detailed assessment of respiratory tissue mechanics. This faster approach may help diagnose and monitor upper airway disorders, assess injury, and guide treatment decisions.
Researchers at University of California San Diego have identified a microbial DNA signature in blood plasma that reliably differentiates primary liver cancer from metastatic colorectal cancer. The finding has potential clinical applications, including early cancer detection and monitoring of high-risk patients.
A team of researchers analyzed sediment cores from the Indian Ocean, revealing that intensive agriculture led to severe soil erosion around 500 years ago. This finding indicates a profound impact of human activities on the environment much earlier than previously believed.
Researchers introduced a non-parabolicity factor to address limitations of traditional models, enhancing prediction accuracy and providing deeper insights into electron transport mechanisms. This breakthrough enables the design of high-performance thermoelectric materials with improved energy conversion efficiencies.
Scientists at Virginia Tech mimic the natural movement of boulders on Racetrack Playa by creating a metal surface with asymmetric grooves that propel melting ice. The discovery has potential applications in rapid defrosting and energy harvesting.
The interactive one-person play 'Every Brilliant Thing' has been shown to reduce suicide-associated stigma among university students who attended the performance, even up to 30 days later. The study found a significant decrease in stigma following the intervention.
A study analyzed 311 Chinese patients with Fabry disease, revealing correlations between enzyme activity, genotype, and clinical symptoms. Males with low residual enzyme activity are at higher risk of early multiorgan damage, while females and late-onset males present milder phenotypes.
Researchers create digital twin facility management system for relocatable modular buildings, improving asset management and decision making. The DT-FMS enhances the lifecycle management of RMBs, minimizing waste and maximizing value through reuse and reconfiguration.
Researchers have developed a novel way for liquid crystals to retain information about their movement, enabling the creation of smart and flexible materials. The breakthrough could lead to advancements in memory devices, sensors, and new types of physics.
MSU researchers have discovered a massive genome in the ground oak plant, containing nearly as many base pairs as the human genome. This discovery could lead to the development of natural pesticides and antimicrobial compounds to combat pests and microbes, with potential applications in large-scale agriculture.
A study in mice found that high triglyceride levels directly cause abdominal aortic aneurysms, challenging the notion that they are merely biomarkers of vascular disease. Researchers identified specific proteins and lipoproteins as causal drivers of aneurysm development and growth.
The ARCHER study aims to determine whether ultra-hypofractionated stereotactic body radiation therapy is non-inferior to hypofractionated radiotherapy in preserving bladder function. Patients will be randomly assigned to receive either 4 weeks of daily or 5 days of ultra-hypofractionated SBRT.
Researchers found that hiring boards may rely too heavily on previous experience, leading to overgeneralization and potentially less successful hires. The study suggests that boards need structured evaluation, multiple perspectives, and a deep understanding of each unique event to hire better CEOs.
A computational framework has been created to understand how the brain's striatum region influences everyday decisions and impaired decision-making in individuals with psychiatric disorders. The study suggests that modulating striosomal activity could be a new approach to addressing psychiatric abnormalities.
Researchers at UC Berkeley developed a method to understand the isotope signatures of methane from different environments using CRISPR. This study can change how scientists calculate the contributions of various environmental sources to Earth's total methane budget.
Researchers are exploring targeting ferroptosis, a regulated cell death process driven by iron accumulation and lipid peroxidation, as a novel strategy to overcome the challenge of cancer stem cells. This approach has shown promise in selectively inducing cell death in CSCs while sparing normal cells.
A new study published in Nature reveals that recent changes in North Pacific Ocean temperatures are driven by human-generated greenhouse gas and industrial aerosol emissions. The prolonged megadrought in the American Southwest is expected to last for at least another 30 years due to the stalled Pacific Decadal Oscillation.
Researchers observe 'many-body dynamical localization' where a quantum system resists thermalization despite continuous driving. The phenomenon is crucial for building better quantum devices and simulators.
Researchers from Heidelberg University and the University of Bern reconstructed Holocene circulation patterns using geochemical analyses of marine sediments. The Atlantic Meridional Overturning Circulation remained stable for long periods but weakened between 9,200 and 8,000 years ago, coinciding with meltwater pulses.
The AGA Incubator: Improving GI Care will select ten startups to participate in a six-month program with monthly workshops and personalized support. The selected companies will have the opportunity to gain investment from the AGA GI Opportunity Fund and connect with potential customers, mentors, and investors.
Isabel Angelo will refine and expand machine learning-driven pipelines for detecting exoplanets, focusing on subtle or unconventional candidates. Her work aims to uncover rare or unexpected planetary systems using cutting-edge AI and astrophysical modeling.
Researchers discovered a large population of critically endangered Plains-wanderers in South Australia's arid interior, defying their previously believed habitat preference. The birds were found to select low-growing shrublands with specific composition over dense native grasslands.
A study in Nepal found that small-scale farmers perceive climate-related risks as a threat to their livelihoods, leading them to stick with agriculture. The researchers recommend providing farmers with climate information and financial resources to explore alternative income sources.
A new study reveals that persistent subtropical ridges create critical conditions for marine heatwave formation. The ridges weaken strong winds, causing the sea to warm rapidly and leading to a substantial reduction in heat loss from the ocean.
A new study found that adolescents with higher blood levels of per- and polyfluoroalkyl substances (PFAS) prior to bariatric surgery regained more weight and had greater increases in waist circumference up to five years after surgery. Researchers believe PFAS exposure disrupts endocrine and metabolic processes, leading to weight regain.
Researchers have developed the world's first microwave neural network processor, capable of performing real-time frequency domain computation and recognizing patterns. The chip consumes less than 200 milliwatts of power, making it suitable for edge computing applications like smartwatches and cellphones.
A new minimally invasive procedure, genicular artery embolization, has been shown to relieve chronic knee pain caused by osteoarthritis in over 60% of patients. The procedure reduces inflammation and blood flow to joints, providing significant improvements in knee pain and stiffness.
Researchers found river otter scat containing parasites that infect prey, indicating otters may play a crucial role in shaping their ecosystems. The study also discovered diverse diets and invasive species among the otters' meals.
A new study found that river otters in Chesapeake Bay eat diverse prey and parasites, including flukes, dinoflagellates, and invasive fish. The researchers suggest that otters may be helping to clean up polluted environments by consuming parasite-infected animals.
A nationwide Swedish study found nearly three times as many young adults under 50 diagnosed with colorectal cancer today compared to the early 1990s. The disease has become two to three times more common in this age group, with underlying causes not fully understood.
Researchers challenge conventional wisdom that grain boundaries in perovskite solar cells are detrimental to performance. Grain boundaries act as 'highways' for charge separation, improving photocurrent and carrier extraction in high-efficiency devices.
The conference brought together leading scholars and industry experts to discuss AI risk, climate risk, green finance, and cryptocurrency regulation. Keynote speakers emphasized the importance of academic collaboration in addressing global financial issues.
A new method for enhanced oil recovery proposed by researchers at The University of Texas at Austin is showing promising results in modeling studies. Alternative carbon carriers are chemical compounds engineered to store larger quantities of carbon molecules in subsurface formations, optimizing greenhouse gas transportation, utilizatio...
Researchers have developed an OAPC strategy to graft a densely packed zwitterionic brush onto Zn anodes, overcoming dendrite growth and hydrogen-evolution side reactions. The resulting OIL-IPS@Zn platform achieves record-breaking stability and efficiency for ultra-long-life aqueous Zn-ion batteries.
A research team led by Prof. Nguyen Tuan Anh from HKUST has made significant strides in understanding miRNA biogenesis using a groundbreaking massively parallel dicing assay. They discovered the GHR motif, a critical determinant of DCL1's cleavage specificity, which operates independently of DCL1's dsRBD and helicase regions.
Researchers developed Zn-doped SrZrO3 ceramics with enhanced solar reflectivity (0.892) and atmospheric window emissivity (0.954), achieving sub-ambient radiative cooling temperatures and net cooling power. The material's phase structure, micromorphology, and spectral radiative properties were optimized through Zn doping.
A new study suggests that exposure to wildfire-derived PM2.5 is linked to increased mortality and morbidity, with a 93% underestimation of the actual death toll. The research estimated 535 annual deaths from all causes due to short-term exposure to wildfire smoke.
Researchers have identified a previously undocumented class of PFAS in the blubber of killer whales, accumulating in fat-rich blubber. This discovery challenges the long-held assumption that PFAS primarily bind to proteins and accumulate in liver or blood.
Researchers developed a single-fibre computer integrating sensing, communication, and computation for accurate human activity recognition. This technology enables significant improvements in wearable electronics, paving the way for next-generation intelligent textiles.
Researchers developed a novel FeCrVNiAl eutectic high-entropy alloy that exhibits remarkable combination of mechanical strength and high corrosion resistance for marine environments. The alloy integrates hierarchical nanoscale precipitates of B2 (NiAl) and L2 (Fe2CrV) phases within its matrix, which are precisely controlled through sol...
Researchers developed an indirect photopatterning approach to create micrometer-scale RGB pixel patterns in single phase network structure, enabling high resolution full-color OLEDs with over 3000 ppi. This method avoids destructive factors and can be conducted using conventional photolithography setups.
The study advances understanding of interfacial failure processes in Na-NASICON batteries, identifying dual-blocking effect and transport rate imbalance as key causes of degradation. Hybrid configurations with liquid electrolytes show promise in improving interfacial stability.
Researchers leverage machine learning to accelerate solid-state battery development, overcoming material interactions and interface instability. AI-powered strategies optimize battery management systems and decode ion transport for improved energy storage.
A study found that most GPs in New Zealand have used AI-scribes to take patient notes, but expressed concerns about accuracy, completeness, and conciseness. Many reported a change in the dynamic of consultations with patients, needing to verbalise physical examination findings and thought processes.
A new database compiled by researchers at the University of Queensland provides a detailed picture of the frog and freshwater fish species on hundreds of Australian islands. The study found that 536 islands have freshwater habitats, with 102 amphibian species and 95 freshwater fish species recorded.
Researchers at UNIST developed a platform to engineer moiré systems with customizable length scales, enabling precise control over electronic properties. The study introduces quasiperiodic patterns with potential to subtly influence electron behavior.
Dr. Schork brings expertise in human longevity and health maintenance to the Center for Translational Science. He aims to intercept disease before symptoms appear using advanced technologies such as genome monitoring and AI-powered analysis.
A UCR-led study found that partisan gerrymandering undermines public faith in elections, leading to disillusionment and erosion of civic behavior. The research connects gerrymandering to broader perceptions of corruption, suggesting that even if a party wins, the victory can feel hollow due to perceived manipulation.
A study of over 30,000 adults found that regular time spent helping others outside the home significantly slows cognitive decline. Informal helping behaviors also provided comparable cognitive benefits to formal volunteering.
A new study suggests that prenatal exposure to acetaminophen may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD), in children. The research team calls for cautious use of acetaminophen during pregnancy under medical supervision.
A Duke-NUS platform has been awarded US$1.5 million to develop new antifibrotic therapies for lung and kidney diseases, conditions with no effective treatment. The project aims to deliver first-in-class antifibrotic therapies using a cutting-edge computational biology approach.