CircRNAs are emerging as powerful regulators of cellular processes, influencing mechanisms such as oxidative stress, apoptosis, and DNA damage. They interact with key biological pathways to shape outcomes in cardiotoxicity, nephrotoxicity, neurotoxicity, and gastrointestinal injury.
The KUNIST platform cultivates globally competitive physician-scientists with five core competencies, including clinical problem-solving, convergent research, and commercialization. The collaboration aims to develop joint educational programs, establish collaborative research laboratories, and build a commercialization support platform.
Recent advances in machine learning enable data-driven design of carbon dots, enhancing their luminescent properties. The technology facilitates rational design and controllable preparation, paving the way for various applications such as sensing, biomedicine, and optoelectronics.
CXorf67, a protein regulating gene activity and DNA repair processes, has been linked to several cancer types including brain tumors, osteosarcoma, and lung cancer. Therapeutic strategies targeting CXorf67-related vulnerabilities, such as PARP inhibitors and EZH2 inhibitors, are being explored.
A recent study found that severe COVID-19 reactivates certain dormant viruses in hospitalized patients, which may contribute to autoimmune disease and chronic conditions. Notably, reactivation of Anelloviridae viruses was associated with long-term physical disability and long COVID.
A study in Arequipa, Peru, found that a decentralized, immune-inspired surveillance model detected 23 infested households compared to just one through the conventional strategy. The new approach allowed local public health staff to accept reports of infestations and expand outreach to nearby areas.
A study found that telemedicine is commonly used for problem-based primary care, particularly for children with endocrine or behavioral health issues. The availability of telemedicine may help increase appointment volume, making more patients accessible to care.
The Gerontological Society of America has announced its newest elected officers, consisting of Vice President Edward Alan Miller and Secretary Sherry A. Greenberg. The organization, founded in 1945, aims to foster excellence, innovation, and collaboration in aging research, education, practice, and policy.
A new study reveals that patients with metabolic dysfunction-associated steatotic liver disease (MASLD) have elevated lipocalin-2 levels and exhibit early signs of cardiovascular and cognitive impairment. The findings highlight the importance of considering MASLD as a systemic condition affecting multiple organ systems.
Ancient human genomes showed differing functional PSPH gene variants, with modern-day phosphoserine phosphatase having the greatest function. The study highlights potential in combining evolution-guided variant prioritization for uncovering functional differences.
Researchers developed a compact antenna-in-package wireless module that achieves 144 Gbps data transmission in the 150 GHz sub-terahertz band, paving the way for future 6G devices. The technology uses phased-array transceivers and dual-polarized MIMO to increase communication efficiency and capacity.
A study found that coating developing raven eggs with non-toxic mineral oil helps protect sensitive prey populations. Raven nests treated with egg oil showed more than doubled sage-grouse nest survival and a 44% increase in relative abundances of sage-grouse.
Researchers at the University of Exeter discovered that a 19th-century estate agent, Brooks & Green, created an early version of Rightmove using cosmorama technology. The discovery reveals how this innovative approach to property marketing paved the way for modern virtual tours and online property previews.
A new platform enables high-performance single photons with exceptional purity and indistinguishability, key resources for quantum communication, networks & computing. The technology addresses scalability challenges in wafer-scale arrays of deterministic emitters.
The Office of Naval Research will host an Innovation Industry Days event from Sept. 21-25, 2026, in Arlington, Virginia. The multi-day event aims to identify and fill future technology gaps across 11 key Focus Areas, fostering collaboration with industry and discussing Navy's pressing research needs.
In a new study, researchers found that wild capuchin monkeys prioritize stones with proven track records of cracking nuts, even if they're not the mechanically optimal choice. This demonstrates that primates rely on durable physical traces to guide their tool selection.
A study by Goethe University found that zoo education programs can genuinely strengthen people's sense of connection to nature, especially among those with low or moderate connections. Programs with direct animal encounters and longer durations showed the strongest effects.
Researchers developed a cost-effective and sustainable approach to produce freshwater by capturing water vapor from the air using specialized materials. The wind-driven strategy utilizes hygroscopic polymer sponges integrated with wind-powered eddy current heating, generating up to 9.9 liters of water per day.
Researchers engineered Cupriavidus necator H16 to convert CO2 into p-coumaric acid, producing a 1,593.3% increase in yield under autotrophic conditions. The breakthrough establishes a framework for CO2-based biomanufacturing and paves the way for producing phenylpropanoids from industrial CO2 emissions.
Researchers created nearly 700 new cancer models derived from patient tumors to aid in drug development. The models, representing 25 types of cancer, are now available for global use, providing a resource for identifying new drug targets and testing potential treatments.
Butterflies worldwide are experiencing extensive climate-induced range shifts, impacting ecosystems globally. As temperatures rise, butterfly populations are adapting to new habitats, altering species interactions and community dynamics.
The Lifestyle Medicine Evidence Repository brings together systematic reviews, meta-analyses, and intervention studies to support clinicians in translating whole-person care evidence into practice. The repository includes studies focusing on lifestyle medicine's six pillars: optimal nutrition, physical activity, restorative sleep, stre...
A collaborative team led by Dana-Farber Cancer Institute has developed 665 next-generation patient-derived cancer models across 27 common and rare forms of cancer. The models are available as a resource to researchers worldwide, accelerating cancer advances with reliable and faithful replicas of original samples.
Researchers found that patients with inflammatory bowel disease (IBD) are at a significantly higher risk of developing psychiatric disorders, particularly depression and anxiety. The study highlights the importance of early screening and integration of psychological care into routine IBD management to improve quality of life.
The KCNE gene family acts as key regulators of voltage-gated potassium channels, controlling their activation and ion flow. These subtle disruptions can have widespread consequences on cellular communication and physiological demands.
A new study found that avoiding three risk factors in middle age is linked to nearly 13 more years without dementia. Participants who had no risk factors lived without developing dementia an average of 30 years, compared to 17 years for those with the three risk factors.
A cohort study evaluates histotripsy's short-term outcomes for liver tumors, highlighting its potential as a treatment option. The study also examines national practice patterns and adult patient results.
Researchers have successfully generated atomic quantum gas mixtures with unprecedented particle flux using a highly sophisticated and compact optical system. The miniaturized laser system developed by Mainz physicists enables precise control of atoms under microgravity conditions, opening doors for future space missions.
A new study found that older adults living in homes with electrical or plumbing problems, insufficient space, or poor lighting are more likely to experience a fall. The study analyzed data from over 5,500 adults aged 65 and over, revealing a significant association between housing conditions and fall risk.
Researchers found that lithocholic acid, a secondary bile acid, can alleviate fatty liver in mice and non-human primates when administered at CR-mimetic doses. The study identified two safe regimens, 0.25 mg/kg and 0.5 mg/kg twice daily, without detectable toxicity.
Using artificial cells, researchers uncovered fundamental physical principles governing cell shape changes and front-rear polarity. They discovered that local interactions within the actin cytoskeleton can generate large-scale shape changes and front-rear polarity without relying on biochemical signaling.
Researchers redesign atomic interface to balance competing requirements, enabling aggressive dielectric scaling and preserving electrical performance in atomically thin transistors. This breakthrough advances wafer-scale manufacturing and paves the way for faster, smaller, and more energy-efficient devices.
Researchers at Shandong University developed a stepwise growth strategy to fabricate high-quality monolayer graphene on silicon carbide. By decoupling buffer layer formation from subsequent graphene growth, they stabilize the SiC surface, eliminate giant step bunching, and achieve uniform graphene growth. The approach enables wafer-sca...
A rare case of uterine carcinosarcoma was reported, characterized by a dual molecular signature that may refine prognosis and guide treatment decisions. The patient's tumor displayed a high-grade endometrioid homologous uterine carcinosarcoma with TP53 and MSH6 genetic alterations.
UT MD Anderson has been ranked No. 1 in the nation for cancer care by U.S. News & World Report for 12 consecutive years, with top rankings in two adult specialties and six common procedures and conditions earning High Performing ratings.
A new study from UT Health San Antonio found that any degree of physical activity can slow cognitive decline in Hispanics. The research, which included 402 participants, also showed that controlling blood sugar levels and cardiovascular health are associated with a slower rate of cognitive decline.
A collaborative study between Insilico Medicine and top research institutions uses AI to identify therapeutic targets for IP-SNSCC, a rare and aggressive subset of head and neck cancers. The study provides the first comprehensive molecular atlas of this disease, enabling future translational research.
A new study reveals soaring infant formula milk prices are causing financial strain, anxiety, guilt, and isolation among UK parents. The research found nearly every parent surveyed reported damage to their mental health, with some feeling regret over having a baby due to the high cost of formula.
Researchers from Adelaide University study how fungal diseases spread across crops by analyzing the location where infection begins — a leaf's waxy surface. They found that mimicking this coating can help understand how it functions and its recognition signals can be turned off, potentially leading to practical crop protection strategies.
A new study published in JAMA Pediatrics found no association between male circumcision and an increased risk of autism. The analysis of nearly 3,000 boys followed from birth into childhood showed that circumcised boys did not have a higher risk of autism compared to uncircumcised boys.
After COVID-19 pandemic restrictions relaxed, Kawasaki disease incidence rebounded in Japan, with distinct age-dependent patterns. Nonpharmaceutical interventions may have contributed to the observed greater rebound in older children, while infants showed minimal changes, suggesting different exposure pathways.
Exposure to pesticides increases the risk of amyotrophic lateral sclerosis (ALS) by 60-70%. Men exposed to herbicides and insecticides are twice as likely to develop the condition as unexposed men.
Scientists developed a scalable solution for robust optical frequency transfer in noisy field environments using digital phase recording and multifunctional relay stations. The system achieved stable operation and fractional frequency instability of 2.9 x 10^-21 at 1 Hz over 2067 km fiber network.
For 15 years, Ochsner Health hospitals have ranked as the best in Louisiana for overall care, with numerous specialties and procedures recognized as High Performing by U.S. News & World Report. The hospital's obstetrics and gynecology service lines, including lung surgery, are among the top-ranked in the nation.
Researchers at SKKU develop a highly efficient catalyst that converts carbon dioxide into industrially valuable 2-propanol, achieving world-record efficiency under ambient conditions. The breakthrough technology uses bifurcated reaction pathways to guide carbon atoms and produce 2-propanol with high selectivity and yield.
Researchers at Weill Cornell Medicine discovered that a protein called BRG1 helps protect cells from ferroptosis, an iron-dependent form of cell death triggered by BTK inhibitors. This finding reveals a potential new therapeutic vulnerability to overcome drug resistance and extend treatment benefits for patients with B-cell cancers.
Researchers mapped kiwifruit genome's chromatin architecture, epigenomic signals, and gene expression to understand how genes shape fruit development. The 3D genome atlas resolves layers of genome organization, including compartments, domains, and loops that influence gene activity.
A study of bull shark behavior found that individuals are slightly more likely to associate and socialise with relatives than unrelated sharks. This 'kinfluence' effect may contribute to both proximity-based associations and directed social interactions, particularly among male sharks.
Researchers at Kyoto University use public Starlink satellite data to estimate thermospheric density around 1,200 satellites. The resulting two-dimensional snapshot provides the first tomographic analysis of its kind, demonstrating high consistency with European Space Agency observations.
A $3.2 million NIH grant will support a five-year study investigating the role of thymulin, a hormone produced by the thymus, in age-related inflammation and cancer. The research aims to explore whether thymulin can improve cancer immunotherapy outcomes, particularly in older individuals.
Researchers identified a fungal cell wall assembly protein as a weak point in plant defense against powdery mildew. Silencing this protein reduced disease severity by up to 75% in controlled experiments.
A study published in Judgement and Decision Making found that participants gave highest ratings to stories generated by AI when attributed to humans. This bias towards narratives written by real people may be due to the assumption of uniquely human qualities required for creative writing, leading people to underestimate AI's capabilities.
A study published in Molecular Psychiatry found that about 65% of patients who developed psychosis after age 40 showed abnormal tau buildup, compared to 15% of healthy older controls. The findings suggest diverse tau-related brain changes may be involved in late-onset psychosis.
A study of nearly 61,000 women in Denmark found that childhood obesity and overweight trajectories were associated with a lower likelihood of giving birth in adulthood. Women with higher BMI trajectories during childhood had a greater risk of childlessness, particularly at older ages.
A team of researchers at UMass Amherst has developed an AI model, DiffuDose, that generates a patient's radiation dose map with gold-standard accuracy in under 23 seconds. This technology has the potential to unlock the full potential of radiopharmaceutical therapy for prostate cancer treatment.
The American Chemical Society has unveiled its new brand, strengthening how it delivers its mission and empowering a global community. The evolved brand brings together scholarly publishing, educational opportunities, and events into a unified identity, making it easier for people to discover ACS resources.
A three-year field experiment found that warming accelerates nitrogen cycling while promoting retention in protected soil pools. This changes where nitrogen goes and how securely it is stored, potentially helping develop climate-resilient nitrogen management strategies for rice production.
Researchers developed a self-powered blue-light photodetector that operates at zero bias, enabling low-power underwater imaging and optical sensing. The device features an asymmetric electrode design and achieves high responsivity and quantum efficiency, making it suitable for real-world tasks.
A cohort study analyzing factors associated with abandoned buprenorphine prescriptions found that US adults are increasingly dropping their medication for opioid use disorder. The study, published in JAMA Network Open, examines the decline of prescribed buprenorphine from 2020 to 2024.
A cross-disciplinary team developed a near-infrared fluorescent dye, SID-788, with excellent biocompatibility and superior ureter imaging performance. The dye enables clear ureter visualisation for at least four to five hours in porcine models using clinical NIR laparoscopes and robotic surgical systems.