The American College of Chest Physicians has appointed Julie Captain as its new Director of Philanthropy, building on the organization's $1.9 million in donations and 530 engaged donors in 2025. With her expertise in legacy and charitable gift planning, Captain aims to grow CHEST philanthropy and expand its impact.
Megalain plays a central role in maintaining cellular balance, organ function, and human health through nutrient transport, neuroprotection, and receptor-mediated endocytosis. Its involvement in drug interactions and toxic responses highlights the need for precise therapeutic strategies.
Vertically resisted plyometric training ranked highest among 10 training modalities for improving change-of-direction speed in trained individuals. The analysis found that this type of training optimizes reactive strength and muscle's ability to switch from eccentric to concentric contraction.
Researchers have developed an experimental drug that tricks cancer cells into consuming more sugar than usual, then blocks their backup fuel source – fat. This approach puts cancer cells under so much stress that many die, demonstrating effectiveness in treating aggressive melanoma in mice.
A study published in Neurology found that between 70% and 85% of people with atypical Alzheimer's disease would not meet eligibility criteria for anti-amyloid treatments. The main reason for exclusion was poor performance on cognitive screening tests, particularly those assessing visual-spatial abilities or executive functioning.
Researchers at NIST successfully transmitted entangled photons through a commercial fiber-optic network, a crucial step towards building quantum networks. The study demonstrates the feasibility of using existing infrastructure to connect distant users and could enable ultra-secure communications and boost quantum computing power.
Researchers found that dietitians recommend fish oil and creatine to support concussion recovery. The study also highlights the importance of a food-first approach, focusing on energy intake, hydration, and healthy eating patterns. More clinical research is needed to inform safe and consistent nutrition advice for athletes.
Scientists at North Carolina State University have created a highly-porous, superadhesive mesh that can capture both large and small microplastic particles, including those as small as tens of nanometers. The mesh is made from sustainable biopolymers and can clean microplastics from both saltwater and freshwater.
A Norwegian nationwide study found that women with pregnancy complications face different long-term cardiovascular risks. Women who had a complication in their first pregnancy and later pregnancies faced the highest risk, while those with no further pregnancies had the lowest risk.
A new study by UBC researchers found that watersheds with greater variation in elevation are less prone to flooding after tree harvesting, while flatter landscapes are more vulnerable. The study also highlights the role of fog in influencing flood behavior and suggests a targeted approach to forest management.
A NIH-funded research project has generated a comprehensive collection of patient-derived tumor models, covering 25 types of cancer from thousands of donor tissues. These models closely match their parental tumors in terms of genetic alterations and gene expression signatures, enabling researchers to explore tumor evolution and diversity.
Previous research found that overconfidence might aid learning, but a new study replicates findings using different methods to find no effect on performance changes between the two groups.
Researchers propose a new analytical approach to determine the limiting velocity of an avalanche crack, revealing that it may propagate at supersonic speeds in certain situations. The findings reconcile conflicting interpretations and provide insights into designing structures impacted by snow masses.
Researchers have identified a unique case of a massive star's demise, marked by an exceptionally faint X-ray burst and the absence of high-velocity jets. This discovery challenges current supernova theories, which typically associate such events with gamma-ray bursts.
Scientists create a two-step anion-exchange strategy to synthesize metastable quasi-1D van der Waals material W6Te6 on a wafer scale. The method utilizes a WS2 template and overcomes the thermodynamic limitation of conventional tellurization, allowing for uniform growth of the material.
Research highlights cellular senescence as a key driver of intervertebral disc degeneration and chronic low back pain. Senescent cells release inflammatory signals that accelerate tissue breakdown and impair repair processes.
Researchers tracked nearly 80,000 adults with type 2 diabetes over ten years, finding those who consistently took their prescribed medication stayed free of serious heart and circulatory complications for over seven extra months. Low adherence was linked to a higher risk of cardiovascular disease, especially in younger adults.
A new AI triage agent will be embedded in Vanderbilt Health's EHR to quickly evaluate patients with Alzheimer's disease. The system will analyze chart information, flag missing details, and recommend referrals for priority or standard evaluation, aiming to reduce wait times from weeks to days.
Researchers developed an experimental drug using AI to target a 'undruggable' protein in pancreatic cancer, slowing tumor growth and improving survival rates. The study demonstrates the potential for AI-assisted discovery of new cancer treatments.
A new study found that six leading AI models exhibit a strong masculine bias in generating stories about animal characters, with only 2% being female. The models use neutral pronouns or avoid them altogether to reduce gender bias, but ultimately erase non-masculine identities.
Researchers developed a new design strategy to overcome limitations in metasurface-based approaches, creating a response that enables strong, fast modulation across a wider range of colours. This advance provides a pathway for compact, high-speed optical devices with potential applications in faster data transmission and future light-b...
A new synthesis paper examines how ecological structures and processes help ecosystems withstand disturbances while providing benefits. The study highlights the importance of 'portfolio effects' in maintaining ecosystem resilience.
A Virginia Tech team analyzed over 1,000 storm surge events to identify distinct patterns that depend on both storm characteristics and coastal geography. The findings could help engineers design infrastructure to withstand unique flood timelines and support better planning and decision making for coastal communities.
A new study suggests that even the smallest non-bird dinosaurs were unusually large due to ecological pressures, such as competition with early mammals. The findings also reveal that powered flight played a crucial role in allowing birds to evolve into tiny species, which is not seen in their dinosaur ancestors.
Researchers at Boston Children's Hospital found that fecal transplants from healthy donors reduced peanut allergy symptoms in some patients. The study suggests that the right bacteria can help restore tolerance to food through bile acid metabolites. Increased levels of immune regulatory cells also protected against allergic reactions.
A new SwRI study provides the first evidence of recent liquid flows to Pluto's surface, suggesting that liquid nitrogen is rising from beneath the Sputnik Planitia glacier. This finding, based on data from NASA's New Horizons spacecraft, indicates a new kind of time-variable feature on Pluto.
Research team led by University of Zurich found Arctic fires occurred 2.5 times more often in lit areas associated with human activity than in climatically similar unlit areas. Effective fire prevention and response can help reduce risks extending far beyond the Arctic.
Researchers developed a conductive e-skin patch that enables real-time wireless monitoring of physiological signals, accelerates wound healing, and promotes smart wound dressing. The patch demonstrates exceptional 99% wound healing rate within 14 days in rat full-thickness wound models.
A U-shaped association exists between LVEDD and mortality in HF, suggesting high risk for both abnormally small and large ventricles. The findings support integrating LV size assessment into routine risk stratification to guide personalized management.
The researchers successfully switched the chirality of phonons within a ferroelectric crystal using an electric field, enabling active control of spin. This breakthrough could lead to the creation of faster and more energy-efficient spintronic devices.
New research suggests that collecting and spraying rainwater on rooftops during hot weather can significantly reduce energy demand for air conditioning and lower urban temperatures. The study found that this approach could cut the number of heatwave days overall and lessen the intensity of extreme heat events.
Researchers used real human brain tissue samples to test the underlying mechanisms of deep brain stimulation. They found that brain cells became more synchronized in communicating, similar to memory formation, while altering gene expression across different types of brain cells.
Researchers have developed a novel solution for dynamic terahertz wavefront control using stretchable single-walled carbon nanotube-based metasurfaces. The devices enable focal-length-tunable and beam-steering capabilities through simple mechanical deformation, opening up new avenues for smart and wearable THz components.
The collaboration aims to turn thousands of data points into actionable insights, helping coaches identify trends and evaluate strategies. By organizing play-level data from football games, the team creates a searchable platform for analysts to quickly test ideas and compare trends across seasons and opponents.
The article highlights Lgr6 as a central regulator of tissue repair and disease development, with its presence linked to stem cell markers and influential signaling pathways. Abnormal expression of Lgr6 is observed in various diseases, including cancer, and is associated with disease severity and treatment response.
A study of comatose survivors treated with therapeutic hypothermia found that longer cooling durations did not improve neurological outcomes. Increasing cooling duration was ineffective in improving patient recovery after out-of-hospital cardiac arrest, suggesting alternative treatments may be more effective.
A new study by Cornell University researchers has found that biofortified millet provides essential nutrients to toddlers without causing adverse side effects. The study showed increased activity in microbial pathways associated with fighting pathogens and improved antioxidant metabolism in children who consumed the fortified millet.
Researchers at Tohoku University identified a new class of small molecules that improves drought tolerance in plants without causing unwanted side effects. The compounds, NS5806 and UA49, inhibit stomatal opening and enhance plant survivability during water scarcity.
Dendritic cell vaccines are engineered to carry tumor-associated antigens, stimulating cytotoxic T lymphocytes to attack malignant cells while sparing healthy tissue. These vaccines have the potential to amplify immune activation and overcome tumor-induced immunosuppression when paired with other therapies.
A new portable blood testing device connects via Bluetooth and uses AI to analyze blood samples, providing real-time health insights. This technology allows for regular monitoring of patients undergoing chemotherapy or taking medications with potential side effects.
The Boston University-Quantitative Population Science and Healthy Cognitive Aging Research Program (BU-SHARP) aims to better understand how and why Alzheimer's disease manifests among certain populations. The center will fund pilot studies, provide technical assistance, and facilitate access to underutilized datasets.
Researchers found that GSTM3 knockdown promotes liver fibrosis reversal through the inhibition of hepatic stellate cell activation via PPARγ signaling. GSTM3 levels were negatively correlated with reversal, suggesting its potential as a diagnostic biomarker.
Researchers developed a new drug called CS18 that targets TopBP1, a biological switchboard controlling multiple cancer-driving pathways. CS18 reduces defenses helping cancer cells survive therapy and increases genes stopping uncontrolled growth.
A study by King's College London has identified an immune pathway that prevents a normally harmless fungus from developing into a fatal infection. The IL-1 family signalling plays a critical role in containing the fungus, suggesting it may be a broader defence mechanism against other fungal species.
According to the study, people with none of these risk factors lived nearly 13 years longer without dementia than those with all three. Women and white participants also had longer survival times without developing dementia. The study highlights the importance of preventing these vascular risk factors in midlife.
A new paper proposes a framework to support more women entrepreneurs, focusing on digital workplace innovation and flexible ways of working. The researchers argue that technology alone is not enough and requires investment in digital skills and inclusive workplace design.
Research found that social media influences travel plans across all age groups, but millennials were the most impacted. Younger generations, especially Gen Z, gravitated toward posts about less common locales.
A study published in Annals of the Rheumatic Diseases found a strong association between air pollution, particularly PM2.5, and increased disease activity and flare risk in RA patients. The study suggests that avoiding prolonged exposure to poor air quality may help reduce disease activity.
The Cancer Dependency Map now includes nearly 150 3D cancer models, expanding its resource to include organoids and spheroids across 10 cancer types. These next-generation models reveal new genetic dependencies and disease-driving mechanisms, particularly in brain and gastrointestinal cancers.
Researchers have developed a numerical model that explains how increasing ultrasonic power reduces chemical reaction rates in sonochemistry. The model shows that oscillating bubbles emit their own sound waves, generating unwanted noise that distorts the ultrasonic field and limits reaction efficiency.
The Osiris 41 volume examines the interrelation between childhood and science, highlighting children's influence and contributions to historical change. Articles challenge traditional norms and assumptions in the field, proposing a more dynamic understanding of this relationship.
Researchers at the University of São Paulo have developed an algorithm for optimal pruning using LiDAR technology, which creates a detailed 3D model of tree architecture. By simulating wind forces on these models, they can identify vulnerable branches and recommend precise cuts to improve tree stability.
A new MUSC study found that patients with college experience and those without health insurance are more likely to decline participation, while younger adults and those who feel unwell or disinterested also opt out. However, many who declined still want help, suggesting it's not the peer support itself that's unappealing.
CircRNAs are emerging as powerful regulators of cellular processes, influencing mechanisms such as oxidative stress, apoptosis, and DNA damage. They interact with key biological pathways to shape outcomes in cardiotoxicity, nephrotoxicity, neurotoxicity, and gastrointestinal injury.
The KUNIST platform cultivates globally competitive physician-scientists with five core competencies, including clinical problem-solving, convergent research, and commercialization. The collaboration aims to develop joint educational programs, establish collaborative research laboratories, and build a commercialization support platform.
Recent advances in machine learning enable data-driven design of carbon dots, enhancing their luminescent properties. The technology facilitates rational design and controllable preparation, paving the way for various applications such as sensing, biomedicine, and optoelectronics.
CXorf67, a protein regulating gene activity and DNA repair processes, has been linked to several cancer types including brain tumors, osteosarcoma, and lung cancer. Therapeutic strategies targeting CXorf67-related vulnerabilities, such as PARP inhibitors and EZH2 inhibitors, are being explored.
A recent study found that severe COVID-19 reactivates certain dormant viruses in hospitalized patients, which may contribute to autoimmune disease and chronic conditions. Notably, reactivation of Anelloviridae viruses was associated with long-term physical disability and long COVID.
A study in Arequipa, Peru, found that a decentralized, immune-inspired surveillance model detected 23 infested households compared to just one through the conventional strategy. The new approach allowed local public health staff to accept reports of infestations and expand outreach to nearby areas.
A study found that telemedicine is commonly used for problem-based primary care, particularly for children with endocrine or behavioral health issues. The availability of telemedicine may help increase appointment volume, making more patients accessible to care.