A TGen-led study reveals that different dementia-related protein pathologies interact with each other in complex ways. The study found that inducing alpha-synuclein and tau before amyloid plaque deposition led to increased levels of defective proteins and exacerbated behavioral impairments.
Penn Nursing scholar Kathryn Connell argues that nursing's 'dual expertise' is widespread yet structurally invisible. She advocates for systemic reforms to support nurse clinician-scientists, who balance bedside practice, research, and personal experience.
A new study led by McGill researchers found that reducing vehicle emissions could prevent over 3,600 premature deaths in Montreal and Toronto. The policy mix includes keeping traffic levels steady and retiring older heavy-duty diesel trucks.
A new study found that climate change affects tree swallow populations in the northern US and Canada, with critical timing constraints and increased year-to-year temperature variability impacting breeding success. The research suggests that these populations are nearing a tipping point, with the greatest risk from warming temperatures ...
A new method called ATTACH identifies strong interactions between T cells and cancer-specific proteins to isolate effective tumor-reactive T cells. This approach overcomes key challenges in immunotherapy development, offering a rapid and accessible way for isolating rare immune cells.
A new study develops the first high-resolution urban air temperature dataset, providing detailed maps of air temperature across cities. This dataset helps explain why satellite-based data often overestimates heat stress and exaggerates disparities between neighborhoods.
A new study reveals that caregiving behaviors in ants are regulated by neural mechanisms that change over the course of an ant's lifetime. The researchers found two brain signaling molecules, Neuropeptide F and Allatostatin A, that act as opposing regulators of behavior, depending on the ant's internal state.
A new study found that specific gut bacteria from children with stunted growth can be passed to their offspring, causing inflammation and damage to the intestinal lining. The researchers identified Campylobacter concisus as a key contributor to this process, which may hold promise for future treatment and prevention strategies.
A new study found that hunger increases the immediate liking and physiological arousal triggered by sweetness, not just its calorie content. Long-term non-nutritive sweetener consumers exhibit heightened activity in a brain region linked to self-control, suggesting these sweeteners may help manage hedonic appeal.
A study led by Erica Heinrich highlights a critical gap in detecting and treating breathing discomfort or dyspnea in ventilated patients. Dyspnea is often hard to recognize, but carbon dioxide levels may be more significant drivers of breathlessness than oxygen levels.
A study by Boston University researchers found that CARB-X-backed projects are nearly five times more likely to advance to clinical trials, while nonfunded projects had less than a quarter advancing. The nonprofit's support led to the award of 160 patents and increased odds of life-saving products reaching patients.
A study published in The Journal of Pediatrics found that nearly half of infants with severe heart defects were born in hospitals without cardiac surgery. Transferring these babies to a cardiac surgical center sooner was associated with shorter hospital stays compared to those transferred later.
The Human Frontier Science Program has reaffirmed its commitment to global life science research, providing strategic investment and visibility for member states' research activities. The program delivers exceptional scientific quality, promotes international collaboration, and develops scientific talent.
Researchers from University of Missouri-Columbia investigated mesenchymal-epithelial transition (MET) in the uterus, a process where cells rebuild the uterine lining after shedding. MET helps restore the uterine lining quickly, but its dysregulation can lead to inflammation, lesions, or cancer, potentially affecting fertility.
A new antiseptic formulation has been developed to eliminate 99.9% of Candida parapsilosis cells, a fungus that causes serious infections in hospitals. The combination of alcohol-based chlorhexidine with eugenol and menthol is more effective than traditional 70% ethanol against this type of disinfection.
A study found that social media helped spread information during the Rolling Fork tornado, but also revealed communication challenges facing rural areas due to limited broadband access and fragmented media. Researchers suggest a need for personalized messaging strategies to address diverse community needs.
A new model proposes rethinking caregiving as a lifelong process, shaping parents' lives over many years. The 'Life Course Care Stress Model' focuses on how caregiving and its impacts unfold over time.
Researchers at UMass Amherst have discovered that grasses grow according to temperature, not light, unlike most other plants. The team used a bioluminescence imaging system to study the growth of purple false brome and found that temperature influences grass growth in complex ways.
Dr. Susan Culican will join a year-long program in Washington D.C., immersing herself in health policy and serving as a senior advisor to federal government leaders. She aims to bridge healthcare experience with policymaking to improve care through evidence-based policy reform.
A new study reveals how generic electron interactions in 3D cubic lattices lead to Weyl topological superconductivity. The researchers found that repulsive electron interactions create a chiral d+id pairing state with an octupolar component, featuring eight gapless Weyl points.
A study in Carlos Botelho State Park, Brazil found that brown howler monkeys rest more on hot, long days when feeding on leaves. The group traveled an average of 531 meters per day, influenced by interactions with other primate species like southern muriquis and capuchin monkeys.
Researchers found that variable-rate seeding (VRS) can help farmers strike a better balance in corn and soybean fields. However, soybeans proved to be more complicated due to their adaptability to weather conditions. The study aims to make farming more accessible and efficient for small land holders using digital tools and data-driven ...
Researchers identified nine typical disaster chain types driven by endogenic and exogenic dynamics, highlighting the need for interdisciplinary integration to understand complex geological disaster chains. The study also emphasizes the importance of 'multi-critical phase transitions' in understanding dynamic processes of disaster chains.
Researchers discovered that ancient farmers used animals like turkeys as biological 'protein concentrators' to access concentrated maize-derived lysine, allowing for high-quality animal protein. This groundbreaking study suggests that maize cultivation and animal management developed together much earlier than previously recognized.
A new study of nearly 1,500 pregnant participants found that following dietary guidelines may reduce exposure to many environmental chemicals from food and everyday products. However, the same dietary pattern does not lower exposure to all chemicals, with higher levels found in certain pesticides on fresh produce.
A study analyzing 60,000 records of flooding, waterlogging, flash floods, landslides, storms, and droughts in Brazil reveals regional impacts. The Northeast had the most affected cities, with landslides and droughts affecting this region the most.
Research shows that road verges with heavy traffic can be deadly for bumblebees, while those with low traffic have a mortality rate of near zero. The study suggests investing in species-rich road verges may not replace traditional conservation habitats.
Researchers have developed a new CRISPR-based method to control protein production in cells by targeting ribosomal RNA. This method, known as TAPIR, has been shown to increase protein synthesis and promote the growth of cancer cells. The results offer new insights into stem cell biology and disease-relevant processes.
A team of University of Oklahoma researchers has developed a noninvasive imaging approach using polarization-sensitive optical coherence tomography (PS-OCT) to evaluate donor livers more comprehensively. This technology could help transplant teams make faster, more informed decisions about liver suitability for transplantation.
Breast cancers diagnosed during the first three years after childbirth are biologically more aggressive than similar cancers in women who have never given birth. The Oncotype DX Breast Recurrence Score suggests biological features associated with a higher risk of recurrence among these patients, including higher-grade tumors.
A new analysis by Ohio State University researchers suggests that expanding energy infrastructure can boost community employment and reduce fossil fuel emissions without significant cost increases. The study's scenario-based framework revealed that even expensive policies taking community health concerns into account are only 0.7% more...
The Bob Woodruff Foundation has granted Boston University Chobanian & Avedisian School of Medicine a one-year grant to expand the Women Veterans Network, providing peer support to women veterans. The funding also supports Strength at Home Couples, a program that enhances intimate relationships and prevents conflict in military couples.
A new study reveals that Amazonian communities use at least one-third of the region's known plant species, totaling 5,796 species. Climate change is expected to lead to a decline in biocultural heritage by 26% from 2060 to 2080, threatening Indigenous cultural identity and ecosystem services.
A Phase III clinical trial is underway to develop a safe, effective, and globally accessible therapeutic for dengue. The trial, led by DNDi, involves 1,000 participants across Brazil, Malaysia, and Thailand. Monoclonal antibodies, currently the most advanced dengue treatment candidates, are being tested.
Research suggests alcohol interacts with Alzheimer's-related brain circuits in distinct ways, depending on the type of pathological change. Alcohol reduced communication in amyloid-beta models but increased it in tau models, highlighting an important principle in biology.
Scientists from Stellenbosch University have isolated a new species of soil bacterium, Dedyshia acidiphilia, from the Kogelberg Nature Reserve. The discovery provides significant advances in understanding rare bacterial species contributing to soil health and nutrient cycles.
A new study finds that a slowing Atlantic Ocean current will strengthen powerful storms in California while reducing snowfall over Greenland. The Atlantic Meridional Overturning Circulation's weakening is projected to increase atmospheric moisture and high-altitude winds, creating more destructive atmospheric rivers.
A newer 'climate-friendly' refrigerant used in car air conditioning systems may already be a significant source of a 'forever chemical' pollutant across Europe. HFO-1234yf is contributing to increasing levels of trifluoroacetic acid (TFA) in the atmosphere, which can form TFA and has been detected in water, plants, food, and human samp...
A study tracking 1,500 residents found that infrastructure within 500 meters of home encourages active transportation. The presence of bike lanes was a key factor in keeping people active and promoting cycling. The expansion of bike lanes and parks has encouraged physical activity and public health benefits in São Paulo.
A new study proposes that chondritic asteroids are escaped satellites from chaotic final stages of planet formation. These mini-moons concentrate and confine molten mineral droplets, forming asteroid-sized bodies that become the parent bodies of chondrite meteorites.
A new study reports that forty percent of women with ovarian cancer only receive a diagnosis after an emergency hospital admission. Women diagnosed through this route are four times more likely to die within two months of diagnosis.
A recent report from the American Cancer Society reveals an urgent picture of a growing global cancer burden. Nearly 21 million people were diagnosed with cancer and 9.8 million died from the disease globally in 2024, with the number of cases projected to reach 34 million by 2050.
Two studies found that California gray wolves primarily eat cattle, with 72% of scat samples containing cattle DNA. Elevated cortisol levels in cattle grazing near wolf packs also indicate chronic stress, affecting their physiology and potentially production rates.
Researchers have discovered a biomarker that can predict and prevent epileptic seizures by detecting a period of neuronal silence before the seizure occurs. The use of this biomarker in neuromodulation therapy has shown promise in reducing seizure duration by up to 93%.
Researchers at McMaster University have developed a targeted approach to treating IBD using bacteriophages, which selectively target harmful bacteria without disrupting the gut ecosystem. The phage therapy significantly reduced gut inflammation and enhanced the effectiveness of steroid treatments.
Research reveals that digital romances can mimic human stages, including exploration, emotional connection, break-ups, and even simulated weddings and pregnancies. Participants shared intimate details and attributed autonomy to their AI partners, raising concerns about privacy and data protection.
A recent study led by the University of Zurich reveals that higher intergenerational educational mobility is associated with significantly higher innovation output in Europe. This association has significant implications for education and economic policy.
A new study finds that higher education and income have varying health benefits across different racial and ethnic groups in the United States. For non-Hispanic Black participants, higher educational attainment was only associated with a 4% reduction in type 2 diabetes prevalence, while higher income was linked to increased obesity rates.
A recent study found that over half of NYC's free-roaming cats are infected with zoonotic parasites. Young male cats, in particular, act as 'super-shedders' of roundworm (Toxocara) eggs, posing public health risks.
A previously unknown species of venomous pit viper has been discovered in the eastern Himalayas, specifically in Medog County, China. The new species, Ovophis medogensis, possesses distinct physical and genetic characteristics that set it apart from its closest relatives.
A new study finds that human cortical neurons have remarkable computational capabilities, surpassing those of other mammals. The researchers developed a new method to measure the complexity of individual neurons, revealing their sophisticated computing power.
A systematic review and meta-analysis found two air pollutants associated with an increased risk of Parkinson's disease. The study suggests that long-term exposure to fine particulate matter (PM2.5) may interact with genetic susceptibility, leading to oxidative stress and neuroinflammation.
A new white paper by 135 EU researchers highlights the decline of wild pollinators, threatening food security and societal functions. The report calls for policy coordination and education on ecosystems and pollinators to reverse the trend.
Researchers discovered natural sulfur and carbon emissions from metamorphic rocks contribute to cooling spikes, while carbon remains in the atmosphere for centuries, influencing ancient ecosystem reorganizations. These findings shed new light on mass-extinction events, such as the Ordovician, Devonian, Permian, and Triassic Periods.
The EU-funded Sister Projects have released a joint white paper calling for strengthened EU action to protect and restore Europe's wetlands. The paper highlights the importance of wetlands in providing essential services such as water purification, flood regulation, and biodiversity support, while also identifying four strategic priori...
Researchers analyzed DNA samples from foraging honeybees, hive workers, and their honey to understand plant-microbe interactions in honeybee ecology. The study found that these complementary sources provide distinct insights into the complex relationships between plants, microbes, and honeybees.
A study suggests geoengineering methods like marine cloud brightening could reduce the impact of extreme weather events during a super El Niño. By targeting natural variability, geoengineering could provide shorter-term benefits with less sociotechnical risk.
Researchers found that beavers are widespread in tidal wetlands and create deep pools of water at low tide, providing habitat for threatened species like Chinook salmon. The study expands the known habitat distribution of beavers and highlights their potential role as ecosystem engineers in estuaries.
The Indian government's plan to blend petrol with ethanol aims to reduce carbon emissions and oil imports, but may compromise on food security, water usage, and sustainable land use practices. The study highlights the need for a more balanced approach to biofuel policies that considers these trade-offs.
Researchers used CRISPR and AI to identify two novel drug targets for psoriasis: the oxytocin receptor and ALOX5 enzyme. Topical gels containing these compounds reduced inflammation in mice as effectively as widely used injected therapies, offering a promising new approach to treating moderate-to-severe disease.