Researchers at Virginia Commonwealth University discovered that intrauterine devices (IUDs) are acceptable for women at high risk of sexually transmitted infections and pregnancy. The study, published in the American Journal of Obstetrics and Gynecology, found lower rates of complications and greater acceptability with the Mirena IUS.
A recent study published in The New England Journal of Medicine found that weekly progesterone injections did not reduce the rate of preterm birth in women pregnant with twins. In contrast, previous research showed that these injections reduced additional preterm births by one-third in women whose previous babies were born prematurely.
Researchers found that progesterone treatment did not decrease the risk of premature birth in women carrying twins compared to placebo injections. In contrast, earlier studies showed a significant reduction in preterm birth among pregnant women with a history of preterm delivery and single-baby pregnancies.
A Mayo Clinic-led collaborative study finds that focused ultrasound treatment of uterine fibroids offers sustained symptom relief and durable outcomes. The more complete destruction of tumors by focused ultrasound results in improved quality of life and lower incidence of severe side effects.
A study of long-term female cancer survivors found that they valued sexuality but were not adequately prepared for the sexual issues introduced by their cancer or treatment. Discussing sexual consequences with physicians matters greatly to these patients, yet infrequent conversations occur.
Women with endometriosis face a higher risk of certain cancers, including ovarian, kidney, and thyroid cancer. However, the risk is not affected by whether or not they have given birth. Conversely, women with endometriosis are less likely to develop cervical cancer.
Scientists successfully extracted and froze eggs from ovarian tissue of girls as young as 5 years old, a breakthrough in preserving fertility in young cancer patients. The study found an average of 8.5 eggs per patient, with a 32% success rate in maturing the eggs in vitro.
A new study from Stanford Medicine found that magnesium sulfate, commonly used to arrest preterm labor, has more mild to serious side effects than the alternative treatment nifedipine. The research suggests that physicians should consider side effects when choosing which drug to prescribe.
Researchers found that mice exposed to ozone before infection died more often than those breathed filtered air. Female mice were also less likely to survive pneumonia exposure compared to males, regardless of genetic variation. The study suggests considering the impact of environmental pollutants on health by gender.
Researchers at Yale University have identified a new regulatory target for the Fragile X mental retardation protein (FMRP), which may lead to new treatments for Fragile X syndrome. The study also found implications for autism, as both conditions share common physiological pathways.
Research from Group Health finds a link between low libido during menopause and disrupted sleep patterns. Women experiencing reduced sexual desire are also more likely to report poor sleep quality and depression symptoms.
International studies show high efficacy for HPV vaccine. The vaccine is highly effective in preventing pre-malignant changes of the cervix and protects against serious HPV-related diseases, including high-grade cervical pre-cancers.
Researchers at Cedars-Sinai are studying a gene that may play a role in the development of polycystic ovary syndrome (PCOS), a condition characterized by insulin resistance, hirsutism, and other symptoms. The study aims to better understand the molecular mechanisms underlying PCOS and potential markers for risk.
A recent study has found that maternal alcohol use during pregnancy significantly increases the risk of extreme preterm delivery. The effects are more pronounced among women aged 30 years and older. Researchers also found that cocaine use was associated with an increased risk, while smoking had a lesser impact.
The University of Illinois at Chicago has received a $7 million grant from the National Institute of Child Health and Human Development to study endometriosis and its effects on fertility. The research aims to develop new therapies and better understand embryo implantation and pregnancy.
Researchers identified a genetic mechanism that permanently shuts down crucial genes in healthy immune system cells, which could be used to target cancer and infection treatments. The discovery was made in normal blood samples and found in a quarter of leukemia samples, highlighting the potential for this mutation as a therapeutic target.
A new HPV vaccine has shown near 100 percent efficacy in preventing the two types of human papillomavirus responsible for most cases of cervical cancer. The vaccine targets HPV types 16 and 18, causing about 70 percent of all cases of cervical cancer.
The study demonstrates that MR-guided focused ultrasound (MRgFUS) is an effective option for treating uterine fibroids, offering rapid and sustained relief from symptoms. The treatment has a reduced need for alternative, invasive treatments in the future.
A study by USF researchers debunks the theory that older women can generate new eggs, challenging a controversial finding made by Harvard scientist Jonathan Tilly. The researchers found no evidence of egg stem cells in ovarian cells biopsied from 12 women between 28 and 53 years old.
Janet Rossant and Anne McLaren receive March of Dimes Prize in Developmental Biology for their pioneering work on mammalian reproduction and development using the mouse model. Their research has significantly advanced understanding of birth defects, genetic predispositions, and reproductive technology.
Researchers found that treating expectant mothers with 17 Alpha Hydroxyprogesterone caproate reduces short-term and lifetime medical costs in offspring by an estimated $2 billion annually. This could lead to significant cost savings for the US healthcare system, making it a promising preventive measure against preterm births.
A study of 4,000 pregnant women found that almost 1 in 5 overweight women required emergency Caesarean sections due to poor uterine contraction. Obese women experienced excessive bleeding following delivery, which was attributed to poor uterine activity.
A new UCSF study predicts a woman's chance of undergoing a hysterectomy based on symptoms and medical history. The study found that women with a combination of symptoms, lack of symptom resolution, and previous GNRH agonist use are more likely to undergo the procedure.
A one-visit screening technique for cervical cancer shows safety, acceptability, and feasibility in Ghana. The single-visit procedure involves applying acetic acid to detect precancerous areas, followed by cryotherapy to eliminate abnormalities.
Researchers at Mount Sinai Hospital in Toronto have developed a non-invasive screening test to detect placental damage in high-risk pregnancies. The test, which combines ultrasound and blood tests, can identify abnormal placental function at 16-23 weeks gestation, allowing for early intervention and improved pregnancy outcomes.
A new study found that pregnant women who gain excessive or adequate weight are four times more likely to have an overweight child. The study suggests reevaluating current pregnancy weight guidelines, as excessive weight gain during pregnancy can influence child health and increase the risk of obesity.
A low-tech operation called symphysiotomy, performed under local anesthesia, can increase the size of the pelvic outlet and permit vaginal delivery of the baby. This procedure has been largely abandoned in developed countries due to its simplicity and effectiveness in addressing maternal mortality in Africa.
A 5-year study found that giving nitroglycerin to mothers in preterm labor led to significant improvement in their baby's health, especially those born between 24-28 weeks. This therapy resulted in cost savings and longer-term health benefits for premature babies.
Researchers have identified a vital protein, PAWP, essential to human reproduction and fertilization. The study suggests that regulating this protein may increase the chances of pregnancy by enhancing fertility.
Preeclampsia researchers found specific proteins in placentas that damage maternal blood vessels, including plasminogen activator inhibitor-1 and soluble Flt-1. Microparticles from the placenta contain high levels of a mysterious protein with unknown function.
Researchers at Yale University have discovered four genetic variants associated with spontaneous preterm birth in Hispanic women. The study found that mothers carrying these polymorphisms were significantly more likely to experience preterm birth. Notably, the ENPP1 variant was linked to the highest risk of preterm birth.
Researchers at Yale University developed a new procedure to estimate individual embryo reproductive potential, potentially reducing multiple births. The method uses proton NMR spectroscopy to analyze metabolic profiles of embryos, correlating with pregnancy outcomes.
Researchers found a potential biomarker for preeclampsia in elevated autoantibodies, associated with increased cardiovascular risk. The study suggests these autoantibodies may also be related to high blood pressure and inflammation.
A team of researchers has identified more than 70 markers unique to ovarian tumor blood vessels, which could lead to new screening and treatment tools. The finding suggests that these markers may be a sign of an aggressive tumor and could help inform treatment decisions.
A recent study by Yale University researchers found that BPA alters the expression of key developmental genes necessary for uterine development, potentially leading to infertility in females. The study used pregnant female mice exposed to varying doses of BPA, revealing a link between BPA exposure and fertility defects.
Pregnant women over 40 years old are at higher risk of stillbirth due to various pregnancy complications. Fetal testing at 38 weeks gestation is most effective in reducing stillbirth rates among older women.
Research shows African American mothers are 3 times more likely to deliver prematurely at 20-34 weeks and almost 4 times more likely to deliver extremely prematurely. Repeating premature births also occur at a significantly higher rate among African American women compared to Caucasian mothers.
Researchers at Yale University discovered a potential reversible cause of first-degree fetal heart block, which impairs the heart's electrical signaling. The PRIDE study found that early treatment with dexamethasone can reverse the condition, but it can progress rapidly to irreversible third-degree block.
Researchers found African-American women are three times more likely to deliver prematurely and nearly five times more likely to experience recurrent preterm births. The study analyzed data from Missouri birth statistics between 1989 and 1997, adjusting for socioeconomic factors.
Private cord blood banking is praised as a way to increase available cells, with Richard Branson's Virgin Health Bank offering processing and storage options. The bank's dual public-private approach donates one-fifth of samples to those in need at no cost.
Researchers used 3-D ultrasound to measure fetal adrenal gland size, identifying a preterm risk of delivery within five days. This method has the potential to assist clinicians in devising better therapeutic and preventive interventions for preterm birth.
Researchers at Yale University developed a novel method to detect abnormal proteins in amniotic fluid, indicating a higher risk of delivering prematurely. The study found that these proteins are associated with inflammation and infection, allowing for earlier detection and treatment of neonatal infections.
A study found a strong connection between muscle damage during vaginal deliveries and pelvic organ prolapse, which causes the uterus, bladder, or bowel to fall down. The research suggests that preventing these injuries can help reduce the rate of pelvic organ prolapse.
Research at Yale University reveals estrogen regulates brain energy metabolism similarly to leptin, leading to a promising avenue for addressing obesity in those resistant to leptin. The study's findings suggest that estrogen may suppress appetite using independent pathways from leptin, making it a potential target for weight management.
A recent study published in Obstetrics & Gynecology reveals that nearly half of young pregnant women are unaware of the safety and effectiveness of modern intrauterine devices (IUD). The study suggests that counseling about IUDs could help these women make informed decisions about contraception.
Researchers demonstrated the safety and effectiveness of continuous-use oral contraceptives eliminating menstrual cycles in a study published in Contraception. Healthy women between 18-49 years old showed significant relief from menstrual cycle symptoms without breaks or placebos.
A University of Rochester study published in Obstetrics and Gynecology journal found that low doses of mifepristone shrink uterine fibroid tumors and greatly improve the quality of life in women who suffer from pain and heavy bleeding. The treatment resulted in a 135% improvement in quality of life for women taking mifepristone compare...
A recent Danish study highlights the risks of postpartum psychiatric episodes, emphasizing the need for effective screening, education, and treatment. The US has not prioritized postpartum illness as a major public health concern until recently, but efforts are underway to implement universal screening programs.
Women who are underweight before pregnancy are 72% more likely to miscarry in the first three months. However, taking vitamin supplements, eating fresh fruit and vegetables daily, or consuming chocolate can significantly reduce their risk.
A study at the University at Buffalo found that synthetic cannabinoid AM-1346 can improve fertility in male smokers with poor semen quality, doubling fertilizing capacity. Researchers believe a communication imbalance between cannabinoid and cholinergic receptor systems may be responsible for nicotine-induced infertility.
Researchers at UT Southwestern Medical Center found that pregnant women who developed an infection of the placenta or nearby membranes have twice the risk of getting it in their second pregnancy. The study analyzed 28,410 women and found a genetic component that predisposes women to intrauterine infection.
A multicenter study found that measuring fetal oxygen levels does not affect the rate of Caesarean section or the health of newborn babies. Researchers tested whether knowing fetal blood-oxygen levels made a difference in the rate of Caesarean section or condition of the newborn infant.
Researchers at Yale University found that competitive female cyclists have reduced genital sensitivity. No negative effects were observed on sexual function or quality of life in the study's young, healthy participants.
A new study from the University of Michigan Health System suggests that hormone therapy may help retain certain memory functions in postmenopausal women. The research found increased brain activity in the prefrontal cortex of participants taking combined estrogen-progestin hormone therapy, compared to those on placebo.
Ghrelin, a stomach hormone, induces food intake by signaling in the brain's reward circuitry, controlling craving behavior. Blocking ghrelin may suppress feeding and seeking out food or energy.
Researchers found that maintenance treatment with escitalopram reduced recurrent depression in patients with major depressive disorder by 38%. Long-term use of the medication also showed safety and tolerance.
A recent U of M study found that treating periodontal disease in pregnant women does not reduce the risk of preterm birth or low birth weight. The study, published in the New England Journal of Medicine, concluded that while treatment is safe and effective, it does not directly affect a woman's risk for these complications.
A new study published in the journal Obstetrics & Gynecology found that midtrimester amniocentesis is associated with a lower risk of miscarriage than previously reported, with a rate of approximately 1 in 1,600 pregnancies. The study refutes the typically quoted 0.5% pregnancy loss rate and suggests it may be even lower than 0.1%.
A large clinical trial found that pregnant women treated for gum disease during pregnancy did not have a significantly lower risk of premature birth. The study, the Obstetrics and Periodontal Therapy Trial (OPT), also showed no increase in adverse events from dental treatment during pregnancy.
A study published in the New England Journal of Medicine found that treating gum disease during pregnancy does not improve pregnancy outcomes, but is safe for pregnant women. Further research is needed to develop more specific treatment guidelines for pregnant women with periodontitis.