Jaime Cury, a renowned researcher at UNICAMP Dental School, received the 2019 William H. Bowen Research in Dental Caries Award for his extensive contributions to cariology research. He has published over 326 peer-reviewed publications on fluoride mechanisms and oral health.
Jessica Scoffield, a microbiologist, receives the AADR Procter & Gamble Under-represented Fellowship for her research on commensal bacteria and polymicrobial pulmonary and oral infections. The fellowship aims to support early-career researchers from underrepresented groups in increasing representation at the faculty level.
Angela Salcedo, Saif Khan, and Hui Chen have been recognized as the 2019 recipients of the IADR STAR Network Academy Fellowship. The fellowship supports research experience in renowned labs before or after attending the IADR General Session.
Newell Johnson, a renowned researcher, has been awarded the 2019 Global Oral Health Research Award by the International Association for Dental Research. Johnson's extensive work on epidemiology, aetiology, and management of common and serious oral diseases has addressed inequalities in global oral health.
Yvonne L. Kapila, a Professor in Orofacial Sciences at the University of Michigan, is recognized for her outstanding mentoring efforts, having mentored over 100 students and trainees globally.
Three researchers win IADR Innovation in Oral Care Awards for developing novel treatments for craniofacial bone defects and periodontitis, with focus on growth-factor-free approaches.
Isabelle Denry received the 2019 Wilmer Souder Award in Dental Caries Award for her contributions to ceramic development and bone replacement. Her research focuses on resorbable bioactive glassceramic scaffolds for dental applications.
Stephen Birch, a renowned researcher at the University of Queensland, has been recognized for his outstanding contributions to dental research with the 2019 Behavioral, Epidemiologic and Health Services Research Award. He is celebrated for his extensive publications and collaborations on various oral health themes.
Researchers have developed bioengineered tooth buds that exhibit features of natural teeth, paving the way for a promising tooth replacement therapy. The new method uses postnatal dental cells to create bioengineered tooth buds with innervation, eliminating the need for immunosuppressors.
The IADR Unilever Hatton Competition and Awards provide an opportunity for junior investigators to present their research, with up to six receiving monetary awards. This year's winners showcased innovative projects in head and neck cancer stem cells, oral cancer microenvironment, and dental treatment needs.
Researchers explored using saliva for early assessment of lung cancer and detection of stress hormones, enzyme levels, and developmental disease biomarkers. Saliva liquid biopsy shows promise in detecting circulating tumor DNA of lung cancer with high performance.
A study published at the International Association for Dental Research found that e-cigarette users, especially those who also use combustible tobacco, are exposed to high levels of carcinogens similar to exclusive cigarette smokers. Non-cigarette tobacco product users are also at risk due to comparable exposure levels.
A study analyzed 62 countries' DMTF Index scores, finding that those under Social Democratic and Liberal regimes had lower rates of tooth decay compared to Conservative and Dictatorial regimes. The researchers suggested creating new typologies to better characterize the relationship between political systems and oral health indicators.
A genome-wide association study identified novel risk loci for non-syndromic orofacial clefts in an African population, refining the genetic architecture of the condition. The study also revealed new genetic associations with cleft lip and palate sub-phenotypes.
Researchers found that germ-free mice exhibited reduced inflammation and atrophy compared to specific pathogen free mice, while probiotic administration improved epithelial thickness. Probiotics also reduced the severity of chemotherapy-induced oral mucositis in mice.
The DEEP study examined the costs and quality-of-life of individuals with persistent orofacial pain (POFP) and estimated outcomes from pain onset. The results showed that high pain levels led to increased healthcare costs and decreased quality-of-life, highlighting the burden of POFP on health.
A new trial found that 5% sodium fluoride varnish is not more effective than other treatments in reducing cavities among preschool children. The study tested two different solutions and showed mixed results.
A recent study has identified novel bacteria in the human mouth using metagenomic analysis, which were not detectable by traditional methods. The research team successfully cultivated these 'microbial dark matter' organisms, known as Saccharibacteria, and found them to be abundant in human saliva samples.
Researchers have developed a new method to measure pocket depths in periodontal disease using photoacoustic imaging and ultrasound. The technique offers high precision and covers all areas of the tooth, outperforming traditional probing methods.
The symposium highlighted new discoveries about oral exRNA biology, providing insights into saliva's unique fraction of exogenous RNA. Researchers discussed leveraging salivary extracellular RNA to improve research and practice in the field of dental and oral health.
Researchers discovered that MMP20, an enzyme essential for tooth development, degrades the basement membrane to initiate enamel formation. The study's findings suggest that MMP20 plays a crucial role in regulating tooth growth and may be involved in various dental disorders.
Researchers developed a novel antibacterial glass ionomer cement with chlorhexidine-encapsulated mesoporous silica, which significantly enhances anti-biofilm ability and maintains mechanical properties. The study proposes a new strategy for preventing secondary caries by using this modified GIC.
A recent study published in Journal of Dental Research found a strong correlation between the amount and frequency of sugars intake among children. Reducing consumption frequency leads to decreased amount consumed, highlighting the importance of balanced diet habits for oral health.
A study found that perinatally HIV-infected youth on integrase inhibitors have a higher risk of dental caries. The study also showed that initiating protease inhibitors at age six or older is associated with less gingival inflammation and lower DMFT scores.
A recent study found that Programmed Cell Death-1 (PD-1) is crucial for the self-renewal and differentiation of dental pulp stem cells. Removal of PD-1 from these cells led to reduced proliferation rates, highlighting its importance in maintaining stem cell function.
Non-syndromic Dentinogenesis Imperfecta is characterized by discolored teeth with a blue-gray or yellow-brown color and translucent appearance. Chronic Unfolded Protein Response (UPR) may be associated with the disorder, caused by mutant dentin sialophosphoprotein (DSPP) gene mutations.
A recent study confirms the effectiveness of water fluoridation in preventing dental caries among US children and adolescents. The analysis found that counties with over 75% access to fluoridated drinking water experienced a 30-40% reduction in dental caries, particularly in primary teeth.
A new special issue of the Journal of Dental Research brings together leaders in the field to discuss the state-of-the-science in head and neck cancer, presenting new early diagnostic tools and mechanism-based therapies.
Research reveals strong connections between longitudinal beverage intakes and adolescent caries experience, with higher sugar-sweetened beverage consumption and lower fluoride intakes leading to increased caries risk. The study emphasizes the importance of adjusting for preventive factors such as brushing frequency in future studies.
Recent discoveries on proteoglycan roles in bone and tooth development have been made, challenging previously held views of their structural function. The symposium aims to provide an update on these findings, which have significant implications for mineralized tissue biology and craniofacial development.
Researchers found that e-cigarette aerosol exposure causes shape changes and narrowing of the orofacial area in developing murine embryos. Flavored e-cigAMs showed greater detrimental effects than plain e-cigAMs, highlighting a potential risk to fetal development.
A study at the University of Minnesota School of Dentistry found a significant decrease in opioid prescriptions after implementing an opioid prescribing protocol. The analysis showed a 47.1% reduction in total opioid prescriptions and tablets per prescription written.
A nationwide survey found that oral and maxillofacial surgeons prescribed more opioids after hydrocodone-containing products were rescheduled in 2014. The study also showed a significant reduction in phone calls requesting refill authorizations after switching to more potent pain medications.
A study found that access to dental services increased for Medicaid children between 2013-2015, with 77% utilizing Type I services and 21% using Type II services. Sealant access rates improved, but sealant utilization remained low, particularly among older children.
The National Institutes of Health (NIDCR) established the DOCTRC Program to develop resources and strategies for regenerating dental, oral, and craniofacial tissues. Two national resource centers were established: The Michigan-Pittsburgh-Wyss Resource Center and the Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration.
A study analyzing hospital data from 2012-2014 found that 1.5% of patients hospitalized for periapical abscess had opioid abuse/dependence, with certain demographics showing increased risk, including younger adults and those without private insurance.
Research investigates the link between chronic periodontitis and age-related macular degeneration, finding a common oral pathobiont, Porphyromonas gingivalis, that can invade human retinal-pigment epithelial cells. The study reveals significant molecular links between CP and AMD.
A study of 2,500 participants found that deployment to combat units was associated with lower odds of e-cigarette use. Soldiers who perceived e-cigarettes as less harmful had a 61% reduction in risk of using them.
Researchers found oral pathogens in colon specimens of polybacterial-infected mice, affecting the microbiome and NO synthesis. The study suggests a link between periodontitis and colon health, potentially impacting motility and antioxidant defenses.
Researchers analyzed preschool-age children's supragingival microbiomes to understand early childhood caries (ECC) development. Notable differences in bacterial species abundance were found among caries-free, restored disease, and untreated disease groups, suggesting that restorative care alone may not reverse ECC-associated dysbiosis.
Research examines subgingival virome in periodontal health and disease, finding lower virus levels in healthy controls compared to diseased subjects. The dominant viruses were members of the Herpes Simplex family, with gram-negative phages predominating in diseases.
Engineered 3D morphogen gradients in hydrogels direct human salivary gland stem/progenitor cell differentiation into ductal and acinar cell phenotypes. Growth factor gradients support salivary gland cell motility and can serve as instructive matrices for tissue engineering.
The study found that silver-nitrate/fluoride-varnish treatment reduced tooth decay in children aged 2-14. However, the treatment did not significantly alter the natural oral microbiome.
The symposium presented new discoveries about oral exRNA biology, including its use as a biomarker for diagnosing disease and tracking its progression. The study of salivary proteome and its diagnostic applications was funded by the National Institute of Dental and Craniofacial Research.
A study found that smoking and obesity individually increase the risk of periodontitis, with their effects being multiplicative. The research discovered unique bacterial patterns in obese smokers and non-smokers, highlighting the need for precision dentistry incorporating multiple metrics.
J. Bernard Machen, a renowned educator and researcher, has been awarded the AADR Honorary Membership for his dedication to public health and dental research. The American Association for Dental Research (AADR) recognized Machen's innovative leadership in dental education and unwavering support for research and discovery science.
Teresa Dolan, a renowned researcher and clinician, was recognized by the American Association for Dental Research (AADR) with the 2018 AADR Jack Hein Public Service Award. The award honors her exemplary service promoting oral health research to a wide constituency.
Grayson Marshall, a renowned scientist and mentor, has received the AADR's highest honor for his dedication to fostering the next generation of researchers. His exemplary record of mentoring students and trainees has led to several pursuing academic careers as mentors.
The American Association for Dental Research (AADR) has recognized William Maixner for his outstanding contributions to chronic pain research, a field he considers a 'hidden epidemic'. He is being honored with the $5,000 award for his exceptional research in this area.
Yogalakshmi Rajendran, an Assistant Professor at the University of California, San Francisco, received the fellowship for her clinical application of autologous blood products in regenerative dentistry and NIH-funded study on oral cavity microflora.