Add BrightSurf on Google Email

John Innes Centre


John Innes Centre scientists solve 60-year-old Septoria mystery

Plant breeders have struggled to combine high yield and resistance to Septoria in wheat varieties, but John Innes Centre researchers have found a genetic connection between the two traits. The study reveals that nearly 60 years ago, breeding decisions inadvertently linked increased susceptibility to Septoria with higher yields.

SourceJohn Innes Centre·JournalMolecular Plant Pathology·DateOct 21, 2016

Solving a plant-based Rubik's cube puzzle

Researchers at John Innes Centre discover a key 'twist' in producing heteroyohimbine compounds, which could lead to new and effective pharmaceuticals. The study reveals the importance of specific amino acid sequences in controlling stereoselectivity during compound synthesis.

SourceJohn Innes Centre·JournalNature Communications·DateJul 15, 2016

John Innes Centre scientists identify 3-D structure of enzyme critical to creation of anticancer compounds in plants

Scientists have identified the 3D structure of iridoid synthase, an enzyme crucial for producing anticancer and antimalarial compounds from plant natural products. The discovery provides insights into the biosynthesis process, shedding light on the unique mechanism used by this enzyme to generate core iridoid structures.

SourceJohn Innes Centre·JournalNature Chemical Biology·DateNov 9, 2015

How plant sensors detect pathogens

A team of scientists has discovered how a plant sensor detects pathogens, bringing unprecedented detail to the 'gene-for-gene' hypothesis. The study reveals that the strength of binding between the sensor and pathogen proteins correlates with the plant's response, opening up new strategies for engineering enhanced resistance.

The potential in your pond

Researchers at the John Innes Centre found that Euglena gracilis has over 32,000 active protein-encoding genes, significantly more than humans. The single cell algae can produce various natural compounds, including vitamins, essential amino acids, and a sugar polymer with anti-HIV effects.

SourceJohn Innes Centre·JournalMolecular BioSystems·DateAug 14, 2015

Progress toward the perfect pea

A research team at the John Innes Centre has identified and studied peas with mutations in genes coding for seed protease inhibitors, which can reduce protein availability by up to 10%. The study provides proof of principle for genetic approaches to improve crop traits, including the removal of allergenic proteins.

SourceJohn Innes Centre·JournalPLOS ONE·DateAug 13, 2015