A study published in Pediatrics found that educational home visits can significantly improve asthma control in children, leading to fewer hospitalizations and reduced symptoms. The research suggests that providing regular asthma education and support can go a long way in managing the condition.
A recent study published in Academic Medicine found that medical students are commonly stuck by needles and often fail to report the injuries. The survey also showed that many medical students were reluctant to report their own safety concerns due to fears about clinical evaluations or time involved in making a report.
Johns Hopkins researchers found that a protein called vascular endothelial growth factor (VEGF) is responsible for the cell overgrowth in chronic rhinosinusitis with polyps. This discovery gives scientists a new target for treating this form of the disease, which typically resists current treatments.
A recent study by Johns Hopkins Medicine suggests that burned-out and depressed surgeons are more likely to report major medical errors. The research found a significant association between burnout, depression, and self-reported medical errors, highlighting the need for better support for surgeons struggling with mental health.
A study found that nearly 40% of children with chronic kidney disease have masked hypertension, which increases the risk of heart problems. Children with masked hypertension are four times more likely to develop left ventricular hypertrophy, a common consequence of untreated hypertension.
Researchers developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks. The treatment targets specific immune cells, showing promise as a new weapon against life-endangering conditions.
Researchers found that children whose mothers had more depressive symptoms experienced more frequent asthma symptoms, while those with fewer depressive symptoms had less frequent symptoms. The study suggests maternal depression is an independent risk factor for childhood asthma symptoms.
A new study from Johns Hopkins Medicine found that extended-release niacin, a B vitamin, offers no extra benefits when combined with traditional cholesterol-lowering therapy in seniors already diagnosed with coronary artery disease. Blood cholesterol levels improved, but arteries did not show significant changes.
A comprehensive program at Johns Hopkins has reduced the need for emergency airway surgery by 67% by providing a standardized cart with essential supplies and training staff on its use. The program's success story highlights the importance of organization and teamwork in improving patient outcomes.
Researchers at Johns Hopkins Medicine found that migraine headaches are associated with more than two-fold higher chances of ischemic stroke. Women with migraines have a particularly high risk, with a 2.9 times higher risk compared to men.
Researchers halted a key study on the benefits of combining extended-release niacin with statin medications to prevent blood vessel narrowing. The study showed that prescribed niacin worked better in combination with a statin than another double-cholesterol-lowering drug combo, reducing carotid arterial wall thickness.
A study of 2,234 initially healthy men and women found no adverse effects from brief episodes of exercise-induced ventricular tachycardia. Regular exercise is still recommended for overall heart health without restrictions.
Researchers have identified desmin protein changes in heart muscle cells that strengthen the link between Alzheimer's disease and chronic heart failure. The study found that misshaped desmin proteins and amyloid-like debris are present in both heart tissue and brain tissue of Alzheimer's patients, suggesting a common underlying cause.
Researchers at Johns Hopkins found that vitamin D deficiency amplifies the negative effects of low estrogen levels on heart health and bones. Men with low vitamin D and estrogen levels were more likely to develop osteopenia and cardiovascular diseases.
A new study from Johns Hopkins Medicine suggests that young athletes should undergo both EKG and echocardiogram screenings to detect early signs of life-threatening heart defects. Abnormal findings were discovered in 36 athletes, highlighting the importance of comprehensive screening programs.
A study by Johns Hopkins researchers found that only 13% of service members with back pain returned to duty, despite treatment. The low success rate is attributed to psychosocial factors and the limited availability of pain management options in war zones.
Researchers at Johns Hopkins University discovered a 1930s gonorrhea medication, acriflavine, that can halt the growth of new blood vessels in cancer cells. By inhibiting HIF-1, a protein essential for tumor growth, acriflavine may one day be incorporated into chemotherapy cocktails to fight cancer.
Researchers have detected distinct molecular disparities between induced pluripotent stem cells and their parental cells, including differences in epigenetic signatures. These findings provide new insights into the fundamental nature of stem cells and may inform therapeutic applications.
A study found that teen girls diagnosed with pelvic inflammatory disease who watched a short educational video were three times more likely to discuss their condition with partners and ensure partner treatment. Despite this, adherence to medication and follow-up remained poor, highlighting the need for in-depth counseling.
Researchers found that men with lower cholesterol levels had a 59% lower risk of developing high-grade prostate cancers, which tend to grow and spread rapidly. The study suggests that targeting cholesterol metabolism may be one route to treating and preventing the disease.
Researchers at Johns Hopkins Medicine found that palmitate marks NMDA receptors for activation, strengthening long-term memory circuits. This reversible process offers possibilities for manipulating memory, potentially enhancing or erasing it.
Researchers at Johns Hopkins School of Medicine found that cells in the retina can remain alive for many months and recover some or all normal function even without a proper blood supply. The study suggests that restoring blood supply to deprived regions of the retina may restore visual function.
Researchers at Johns Hopkins Medicine have identified over 300 proteins that control genes, a newly discovered function for previously known proteins. These 'moonlighting' molecules may play a key role in human complexity, with potential implications for understanding gene regulation and cellular behavior.
A comprehensive review of flu seasons past reveals that pregnant women are at significant risk for serious flu-related illnesses and complications, which far surpass the risks associated with injectable vaccines. The study confirms existing CDC recommendations for prioritizing pregnant women in flu vaccination.
A study by Johns Hopkins Medicine found that uninsured children were 60% more likely to die in the hospital than those with insurance. Researchers estimate that thousands of children may have been saved if they had health coverage, highlighting the need for healthcare reform.
Bioethicists at Johns Hopkins University pose questions about the moral status of embryos created from induced pluripotent stem cells. The researchers advocate for clear ethical oversight to address concerns about the scientific achievement.
Muscle weakness is a common side effect of long stays in intensive care units, increasing mortality rates and prolonging hospital stays. New classification scheme proposed by researchers helps identify treatable complications acquired in ICUs.
Scientists found a newly discovered gene, KIAA1212, linking to schizophrenia and autism susceptibility genes. They successfully 'rescued' damaged brain cells using rapamycin, a drug acting on mTOR protein.
Scientists have identified a new type of cell in the inner ear that carries sound signals to the brain, responding only to extremely loud sounds. The discovery sheds light on how the human ear processes sound and may have implications for understanding hearing loss.
A new study by Johns Hopkins researchers suggests that physicians have less respect for obese patients, with higher BMI associated with lower levels of respect. The findings raise questions about whether physician attitudes towards obesity impact patient care and health outcomes.
A Johns Hopkins study found that Hispanic children diagnosed with brain tumors receive specialized care at one-third the rate of other children, despite efforts to equalize access. The research highlights persistent gaps in care among certain patients and raises concerns about the future impact on this growing demographic.
The Johns Hopkins Center for the Epigenetics of Common Human Disease has been awarded a $16.8 million NIH grant to advance genomics research. The team will focus on studying epigenetics' role in diseases such as bipolar disorder, aging, and autism.
Researchers at Johns Hopkins Medicine have identified a distinct set of white blood cells called regulatory T cells that play a crucial role in wound repair after serious lung injury. The study found that these cells can be sped up or slowed down, either aiding or hindering healing in severely damaged lung tissue.
Critically ill patients in ICUs can benefit from mild physical therapy exercises to reduce muscle wasting and promote recovery. The new approach involves introducing muscle-strengthening exercises early into treatment plans, with patients exercising while on ventilators and other life-support equipment.
A small study of 101 patients found that a one-minute eye movement exam performed at the bedside worked better than an MRI to distinguish new strokes from other less serious disorders. The quick and low-cost test caught more strokes than the current gold standard, suggesting a way to improve care and avoid high costs.
Researchers at Johns Hopkins School of Medicine discovered that the antioxidant protein Prdx1 controls the activity of GDE2, a critical protein for spinal cord neuron development. The study found that Prdx1 breaks a chemical bond between amino acids in GDE2, activating it to promote motor neuron differentiation.
Researchers at Johns Hopkins Medicine have identified unique characteristics of lung cancer in never-smokers, including exposure to second-hand smoke and radon gas. The guide recommends specific treatments, such as EGFR inhibitors, for patients with genetic mutations.
Johns Hopkins researchers identified a strong genetic alteration associated with the ability to clear hepatitis C without treatment. The study found that people carrying a specific variation of the IL28B gene were more likely to successfully eliminate the virus from their bodies.
Johns Hopkins researchers find two force-sensitive proteins, myosin II and cortexillin I, cooperate to sense cell shape disturbances and resculpt cells for smooth division. This discovery could lead to new targets for diagnosing and treating diseases like cancer.
A study found that daily chlorhexidine bathing can dramatically reduce the risk of deadly bloodstream infections in ICU patients. Chlorhexidine glutonate is a cheap and effective antibacterial agent available for just $6 per bottle or $0.33 per packet.
A Phase I clinical study found that GDC-0449 inhibited the Hedgehog signaling pathway in patients with advanced basal cell skin cancers, with half showing tumor regression. Another patient with medulloblastoma showed significant tumor shrinkage and improvement in symptoms.
A new study by Johns Hopkins researchers reveals that HIV subtype D is associated with a significantly higher likelihood of developing dementia. The study found that nearly all (89%) patients infected with subtype D developed dementia, whereas only about 24% of those infected with subtype A showed signs of the condition.
A new study by Johns Hopkins Medicine, Duke and Wake Forest suggests that disclosing financial conflicts of interest to research participants may not be sufficient. The study recommends establishing sound policy and practices for disclosure and management of financial interests.
Healthcare patient safety interventions face complexity due to diverse populations and technologies. Guidelines from Johns Hopkins experts suggest prioritizing rare but devastating errors over more frequent systemic problems.
Researchers found that strains of Bacteroides fragilis dupe immune cells into allowing runaway colon tissue inflammation, a precursor to malignant growth. High levels of pStat3 and Th17 activity in infected mice were linked to chronic inflammation and tumor development.
A small study found that 18 children with severe milk allergies could safely consume milk and dairy products, with reactions decreasing over time. Regular exposure to milk was needed to maintain tolerance.
Scientists identify key molecular players responsible for reversion of adult cells into a primordial, stem cell state. By reducing activity of Jak and STAT proteins, researchers found fewer cells to revert back to stem cells, with only 60% regaining their stem cell population.
Scientists discovered that two cancer-promoting genes enable tumor cells to grow and survive under conditions where normal cells die. The KRAS and BRAF mutations allow cancer cells to thrive in environments with limited glucose, which may be used to develop new treatments.
Researchers found stem-like cancer cells that share characteristics with healthy stem cells, including unlimited lifespan and migration properties. These cells were localized in the same tissue location as bladder stem cells and showed increased activity in genes related to cell proliferation and metastasis.
A study by Johns Hopkins Medicine found that long-term memory losses and cognitive problems after bypass surgery are caused by coronary artery disease, not the heart-lung machine. Researchers discovered significant cognitive decline in patients with no use of heart-lung devices.