A new study from the University of Michigan Stroke Program reveals that women and Mexican-Americans are at a higher risk of suffering a type of stroke related to a ruptured brain aneurysm. Women had a 74% greater chance, while Mexican-Americans had a 67% greater chance, compared to non-Hispanic white men.
Researchers identified SPINK1 as a biomarker for an aggressive type of prostate cancer that accounts for 10% of cases. The discovery could lead to a simple urine test to diagnose this variation, which tends to recur quickly.
A new study from Michigan Medicine found that nearly half of heart surgery patients experience sustained high glucose levels, even without a history of diabetes. Patients with obesity, older age, and high blood sugar levels two days after surgery are most likely to need temporary insulin treatment.
A new review suggests that participants' desire for transparency outweighs bioethicists' concerns about potential negative psychological consequences. Volunteers generally want access to aggregate study results and some individual results if relevant to their lives. However, individual results can be overwhelming and expensive to provide.
A U-M study found that patients with poor physical quality of life, particularly those experiencing pain, eating, and speech difficulties, are significantly less likely to survive. The researchers recommend routine quality of life assessments for head and neck cancer patients to identify potentially aggressive tumors.
Researchers found that topical retinoic acid, carbon dioxide laser resurfacing, and injections of cross-linked hyaluronic acid improve skin's appearance and resistance to bruising by stimulating new collagen production. Collagen collapse is a key factor in skin aging, but fibroblast cells can recover and make more collagen.
A study found that even when patients with diabetes present with high blood pressure, there's only a 50-50 chance of receiving treatment. Uncertainty about the patient's blood pressure and other medical issues contribute to this 'clinical inertia'. More systematic guidelines for monitoring blood pressure in people with diabetes are needed
Lubiprostone has been shown to significantly improve all IBS-C symptoms in women, including abdominal pain, bloating, and constipation severity. The drug is also effective in treating IBS-C for up to one year, with improved stool consistency and reduced nausea and diarrhea.
A new study from the University of Michigan Comprehensive Cancer Center found that black patients are 23% less likely to receive chemotherapy and 12% less likely to receive radiation therapy for rectal cancer compared to white patients. Despite similar rates of consultation with oncologists, disparities in treatment initiation persist.
Researchers at U-M Comprehensive Cancer Center found that HPV-positive tumors are more responsive to chemotherapy and radiation treatments. The study also identified biomarkers that can determine which patients are most likely to survive and thrive with tailored treatment plans.
New University of Michigan Depression Center research shows depressed people have fewer serotonin & opioid receptors, varying greatly among individuals. The number of receptors affects symptom severity and treatment response, suggesting personalized medicine approaches may be more effective.
A new study reveals that women are more likely to experience atypical symptoms such as nausea and jaw pain during a heart attack, leading to delayed treatment. Women were also less likely to receive life-saving treatments like beta blockers, statins, and angioplasty compared to men.
A new study reveals that police and fire officers who give interviews can significantly improve the media's coverage of risk factors and prevention for injuries, accidents, and fires. The study analyzed thousands of hours of local news broadcasts and found that such stories are more likely to include prevention information.
A new study confirms that black women have less urinary incontinence than white women, but when they do develop it, the condition tends to be more severe. The study also found that black women experience 'urge incontinence' twice as often as white women.
A University of Michigan researcher is conducting a clinical trial to test the effectiveness of Zoloft on anxiety patients. The study aims to determine if genetic variations can predict an individual's response to anti-anxiety medication.
A new University of Michigan study finds major gaps in hospice care availability across the US, attributed to low Medicare funding and reliance on charity. The study shows that communities with lower average incomes and education levels have fewer hospices, while areas with higher incomes and educated populations have more.
A new policy implemented in a Michigan clinic helped identify 35% of patients misusing opioid medications, while steering dependent patients to treatment. The approach logged and screened all patients receiving opioids for non-cancer pain, with the goal of protecting doctors' ability to prescribe these drugs.
A new study suggests that minimally invasive carotid stenting is as effective as open surgery in preventing strokes among high-risk patients. After three years, patients who underwent stenting had similar rates of stroke, heart attack, or death compared to those who received traditional open surgery.
A new study found that rats fed tart cherry powder on top of a high-fat, Western-style diet had lower body weight, fat mass, total cholesterol, triglyceride, TNF-alpha, and IL-6 levels. These findings suggest a potential link between tart cherry consumption and reduced cardiovascular risk factors.
A new study shows that a combination of two drugs can lower blood pressure and reduce cardiovascular risk by 20%, outperforming an ACE-diuretic combination. The therapy has the potential to improve control rates to over 80% and alter current guidelines for treating high blood pressure.
A new mathematical model could revolutionize how scientists study cellular signaling pathways, potentially leading to more effective treatments for cancer and other diseases. The model takes advantage of today's computing power to provide a superior tool for understanding the complex interactions between cell signals.
A team of University of Michigan scientists has identified a possible link between genetic mutations and toxic substance exposure in the development of motor neuron disease. The study found that abnormal protein changes caused by organophosphate exposure may contribute to the disease, offering new leads for diagnosis and treatment.
Researchers found that only about 45% of cases used tumor markers AFP and HCG, with all three markers measured in just 16% of the time. This suggests low usage rates despite the importance of tumor markers in showing patient response to treatment and disease recurrence.
Researchers found that mice treated with low-molecular weight heparin before or after vein damage healed faster than those not treated. The study's findings support the use of heparin as a preventative measure for deep-vein thrombosis, which affects millions of Americans each year.
A study by Michigan Medicine researchers found that pain levels in patients with fibromyalgia decreased when glutamate levels went down. This suggests that glutamate may play a role in the disease and could be used as a biomarker of disease severity, leading to potential new treatments.
A national study found that patients with high cholesterol who received nutrition counseling from registered dietitians were able to reach their LDL cholesterol goal in approximately eight months. The study, which included data from 377 patients, showed significant reductions in cholesterol levels and weight loss among those who follow...
Researchers at the University of Michigan have designed a small molecule that activates the p53 protein to kill tumor cells without causing damage to normal cells. The new drug, MI-219, is highly effective in cell cultures and appears safe for use in animals.
Researchers at Michigan Medicine have developed an oil-based nanoemulsion vaccine that produces strong immunity against smallpox and HIV in animal studies. The vaccine uses a mixture of soybean oil, alcohol, water, and detergents emulsified into ultra-small particles to trigger the body's immune response.
Researchers at Michigan Medicine created a device that measures metabolic stress, detecting eye disease before symptoms appear. The instrument provides accurate results in detecting vision loss and characterizing disease progression.
A new study from Michigan Medicine found that obese children are more likely to experience difficulties with airway obstruction and other breathing-related functions during surgery. The study also reveals a higher incidence of illnesses such as asthma, hypertension, sleep apnea, and Type II diabetes among obese children.
A new study found that cognitive impairment is decreasing among people aged 70 and older, with better education and financial status being significant contributors. The decline in cognitive impairment may be attributed to improved cardiovascular health, as risk factors like high blood pressure and smoking were more prevalent in the 1990s.
A new study suggests that taking N-acetylcysteine before a CT scan or angiogram can protect at-risk patients from kidney damage caused by iodine-containing contrast agents. The inexpensive drug, which is quick, convenient and widely available, appears to be the best choice for those with weakened kidneys.
Researchers found that patients with depression may not experience improvements in hopefulness until several weeks or months after their depressive symptoms lift. This delay can lead to reduced adherence to treatment, increasing the risk of suicidal thoughts and behaviors.
Researchers found that BRCA1 plays a role in regulating breast stem cells, which can develop into cancers. Women with BRCA1 mutations have a high incidence of breast cancer due to the unregulated proliferation of these stem cells.
A new study suggests that myostatin inhibitors, currently under study for medical conditions and bodybuilding, may also increase the risk of small, brittle tendons making muscle injuries more likely. Researchers found that myostatin's absence led to shorter, stiffer tendons in mice.
Researchers find a direct link between visceral fat and atherosclerosis, a condition that causes blood vessels to harden and narrow. The study suggests that anti-inflammatory medication could be used to reverse the process and reduce heart disease risk.
Research by Michigan Medicine suggests that overactive nerves in the head and neck may contribute to tinnitus. Acupuncture and trigger point therapy may be effective treatments for people with 'ringing in the ears'. The study found hyperactivity of touch-sensing neurons in animals, which could lead to new insights into the condition.
A new study found that reducing drug co-pays for employees with chronic illnesses increased the use of preventive medicines, leading to fewer hospitalizations and emergency room visits. The study involved over 35,000 employees and showed significant increases in use of important medications.
A new study from Michigan Medicine finds that congestive heart failure patients experience high disability rates and increased need for nursing-home care. The condition imposes substantial burdens on patients, families and the long-term care system.
A study found that nearly half of hospitals lack a system to track which patients have a catheter, and three-quarters lack a system to monitor catheter removal. Less than 10% use an approach proven to reduce UTI rates and decrease catheter time.
Research found that 30% of patients with ventricular arrhythmia received life-saving defibrillation more than two minutes after cardiac arrest, leading to significantly lower survival rates. Hospital characteristics, such as small size and lack of continuous monitoring, were associated with delayed defibrillation.
A new study from the University of Michigan Comprehensive Cancer Center found that only a third of breast cancer patients discussed reconstruction options with their surgeon. Women who did discuss reconstruction were four times more likely to choose a mastectomy, highlighting the importance of informed decision-making in surgical choices.
Researchers have discovered that the turbulence in electrical waves underlying ventricular fibrillation can be scaled using a universal formula related to body mass, and that genetic variations in mice may also apply to humans. This breakthrough paves the way for better translation of VF research results from animals to humans.
A national study suggests that infants with complex congenital heart defects have a lower risk of dying if treated at experienced hospitals. The study found significant differences in mortality rates depending on the number of procedures performed at each hospital, with centers treating more cases having lower mortality rates.
A new survey from Michigan Medicine suggests that when women are told their risk of breast cancer is above average, they're more likely to take a hypothetical pill and overestimate its benefits. The study highlights the importance of considering individual risk information when making medical decisions.
A new marker, ALDH1, has been identified that can be used to detect and characterize cancer stem cells in breast tumors. These cells are responsible for fueling a tumor's growth and are linked to worse outcomes.
A comprehensive genetic analysis suggests that the ancestors of Native Americans originated from a single source in east Asia, with a unique genetic variant widespread across both continents. The study's findings support the land bridge theory and hint at evidence for coastal migration to South America.
Researchers found that bortezomib selectively inhibits melanoma tumor cells by overactivating the cancer-promoting gene c-MYC, leading to increased production of NOXA and promoting cell death. The study suggests a novel treatment strategy for various types of cancer.
A study by Michigan Medicine found that a pedometer program that counts every step, regardless of duration, is more satisfying for people with diabetes. This approach led to increased walking and better adherence compared to structured goals.
A new study from Michigan Medicine found that nasal irrigations with saline are more effective than saline sprays in providing short-term relief of chronic nasal and sinus symptoms. The treatment resulted in a clinically significant improvement in quality of life, with participants experiencing 50% lower odds of frequent nasal symptoms.