A new study aims to determine the effectiveness of drug therapy, psychotherapy, or a combination in treating major depression in teenagers. The study, administered by Northwestern University Medical School, will enroll participants between 12-17 years old with clinician-diagnosed depression.
Researchers at Northwestern University have developed a method to create triangular nanoprisms in large quantities, which can be used as new diagnostic labels for detecting biological weapons and diseases. The nanoparticles' unique optical properties make them a promising building block for detection science.
Researchers create self-assembled nanofibers resembling collagen fibrils in real bone, enabling mineralization and promoting cell attachment. The synthetic nanofibers offer potential applications in bone fractures, tissue regeneration, and electronics.
Physicians who participate in executions do so out of a sense of citizen obligation, but this involvement mostly advances pro-death penalty political purposes. Medical professionals have long opposed physician participation in executions due to ethical concerns.
A second gene mutation for the inherited form of ALS has been discovered by Northwestern University researcher Teepu Siddique. The newly identified gene, alsin, is responsible for juvenile inherited ALS (ALS2), a rare and slowly progressive disease affecting young populations in North Africa and the Middle East.
Researchers at Northwestern University have developed a new imaging method that uses high-temperature superconductors to improve Magnetic Resonance Imaging (MRI) technologies. The breakthrough, led by Professor William Halperin, enables the study of superconducting vortices in tiny crystals with unprecedented spatial resolution.
Neuroscientists identified brain regions activated by eating chocolate's rewarding and aversive aspects, offering insights into addiction and eating disorders. The study provides a novel model for understanding addiction using primary reinforcers like fat and sweet.
Researchers at Northwestern University determine the molecular structure of a metallochaperone (CCS) bound to its target protein (SOD), providing new insight into a metal transfer mechanism and shedding light on diseases related to copper and oxidative stress.
Researchers used NMR technology to analyze lipoprotein size and concentration in 262 patients with high-risk heart disease. The study found that a commonly prescribed statin, pravastatin, was equally effective in lowering bad cholesterol levels regardless of LDL particle size.
Geologists propose that high-pressure ice could accumulate in planetary interiors during subduction, potentially influencing tectonic activity and volcanic eruptions on Earth and Mars. This process may also impact the planet's thermal balance, with changes in water state affecting dynamics and evolution.
Researchers used contrast-enhanced MRI to assess heart damage in 50 patients. The technique distinguished between reversible and irreversible injury, allowing for more accurate prediction of surgery success.
Researchers at Northwestern University are analyzing DNA samples from families with children born with spina bifida to identify genetic traits and risk factors. The study aims to predict the likelihood of having a child with the condition, giving parents power to make informed decisions.
Researchers at Northwestern University are conducting six studies on the role of diet and hormones in breast cancer prevention and development, as well as innovative translational therapies.
A study at Northwestern University aims to assess whether an experimental drug can reduce carcinogens produced by cigarette smoke, potentially preventing lung cancer. Participants must be heavy smokers with a history of failed quit attempts and no medical problems.
A Northwestern University study collects data from nearly 1,000 dying patients to provide new insights into the care of terminally ill individuals. The research reveals that good communication with physicians and nurses, as well as spiritual/religious practices, contribute to a greater sense of purpose and personal acceptance.
In a two-year study, researchers at Northwestern University are using phytoremediation to reduce lead poisoning in Chicago's West Town community. They have planted different types of grasses and vegetation in 40 homes to test their effectiveness in removing lead from the soil.
Researchers at Northwestern University are developing a non-destructive test to detect small flaws, latent flaws, and general degradation in commercial aircraft wiring. The FAA is funding the $450,000 grant, which aims to improve aircraft safety by identifying critical degradation levels of aging wiring without removal from its location.
Northwestern University has received nearly $1 million in NSF funding to develop special robots called cobots that assist humans in heavy materials handling. Researchers also plan to create a technology to distribute computer software for large-scale optimization problems via the Internet.
Renowned scientists and clinicians will discuss recent advances in breast cancer science and treatment, including new developments in imaging techniques, hormone replacement therapy, and alternative therapies. The symposium will feature prominent speakers from top medical institutions.
Researchers at Northwestern University have developed a novel DNA detection method that is more accurate, less expensive, and easier to use than conventional methods. The scanometric DNA array detection method uses gold nanoparticles and a flatbed scanner to detect target DNA with high sensitivity and selectivity.
Researchers found that high-dose immune suppression and stem-cell transplantation can lead to long-term remission in lupus patients. The treatment approach has implications for the treatment of other immune disorders, including multiple sclerosis and some types of cancers.
A specific gene, espin, is linked to deafness and abnormal behaviors in jerker mice. The mutated gene affects hair cell function, leading to false signals sent to the brain, which causes animals to move erratically.
Researchers at Northwestern University are developing novel architectural and compiler concepts to reduce energy consumption in specific military applications by a factor of 100 times. This technology will also benefit civilian applications, enabling longer battery life and increased functionality in portable devices.
Scientists at Northwestern University have identified the structure of the interaction complex between two molecules central to the allergic response in humans. The discovery could lead to a new class of drugs that target allergies at their source, preventing symptoms like itching and congestion.
Research highlights the difficulties faced by rural low-income families in transitioning from welfare to work due to limited job opportunities and lower wages. Despite recent economic growth, many rural areas lack essential workplace supports and infrastructure, hindering employment prospects.
Researchers at Northwestern University have discovered that the growth-associated protein GAP-43 enhances learning and memory in the mammalian brain when overexpressed in a phosphorylatable form. This finding could lead to new treatments for memory loss and learning disorders.
A breakthrough in nanolithography transforms dip-pen nanolithography into a parallel process, paving the way to mass-producing tiny nanostructures. The new eight-pen nanoplotter can create identical patterns with consistent line widths and requires only one feedback system.
Researchers at Northwestern University found that adult memories of childhood events and relationships are no more accurate than chance, contradicting the idea that memory is a continuous tape. The study's findings have important implications for psychiatrists and mental health professionals who rely on patient reports.
Scientists at Northwestern University discovered that polyglutamine aggregates are toxic and can bring healthy proteins to aggregate with them. The growth of these aggregates can be suppressed by molecular chaperones called heat shock proteins. This finding provides a new model for understanding the common pathology of neurodegenerativ...
A new study by Northwestern University Medical School researchers found that high blood sugar levels are associated with an increased risk of pancreatic cancer death. The study analyzed data from nearly 40,000 men and women who were screened for cardiovascular disease risk and followed up for an average of 25 years.
Researchers at Northwestern University have successfully cloned a gene called Prestin, which codes for a protein that plays a critical role in the functioning of outer hair cells. The discovery could hold promise for treating hearing disorders and developing new biocompatible motors for nanotechnology applications.
A Northwestern University research team has discovered the first enzyme to play a role in the mammalian circadian clock, contributing significantly to understanding of circadian rhythm-related problems. The identified casein kinase I epsilon (CKIe) enzyme interacts with PERIOD proteins, affecting the timing of the circadian cycle.
Researchers at Northwestern University report a rare but potentially fatal blood disease known as thrombotic thrombocytopenic purpura (TTP) associated with clopidogrel use. The disorder causes mass destruction of blood platelets, anemia, and other severe symptoms.
Researchers developed a novel method to improve polymers by changing their organization using small molecules as additives. The new method creates a gel-like material with enhanced mechanical and thermal properties, as well as unique optical properties, including birefringence and wavelength reflection.
A Northwestern University researcher is leading a five-year, $5 million National Cancer Institute-sponsored study to improve current methods and evaluate new tests for detecting early-stage ovarian cancer. The study aims to identify novel biomarkers that can detect ovarian cancer in its early stages.
Donald Saari's research on voting paradoxes and weighted voting systems has shown that simple plurality voting can produce misleading results. He suggests using the 'Borda count' system, which assigns weighted votes for each candidate, to better reflect voters' true wishes in elections.
A groundbreaking study led by Northwestern University aims to understand the health needs of delinquent children over time. The longitudinal study examines factors such as service integration, treatment effectiveness, and HIV/AIDS risk behaviors among 1,800 racially diverse youth.
A genetic defect in a protein receptor has been identified as the cause of Leydig cell adenoma, a rare testicular tumor that triggers early puberty in boys. The mutation leads to rapid growth and overproduction of testosterone without normal hormonal signals.
Researchers at Northwestern University create a new technology called nano-plotter, which enables precise placement of multiple molecules on a solid substrate. This innovation could lead to advancements in molecule-based electronics, molecular diagnostics, and catalysis.
A study by Northwestern University researchers finds that linezolid is highly effective against a range of gram-positive bacteria, including those resistant to vancomycin and oxacillin. The antibiotic showed potent activity against all isolates tested, making it a promising new treatment option for patients with drug-resistant infections.
Amputation rates among elderly Americans have risen due to limited capacity for bypass surgery and angioplasty procedures. Diabetes remains a major risk factor, with 40-60% of amputations involving diabetic patients.
Physicists at Northwestern University have demonstrated that superfluid helium-3 can conduct sound waves transversely, a property previously observed in solids. This discovery provides conclusive proof of the existence of transverse sound waves in liquid helium-3 and opens up new possibilities for studying its internal structure.
Researchers at Northwestern University have halted motor neuron destruction and slowed ALS progression using GDNF gene therapy in laboratory mice. The approach may one day prove effective in treating humans with ALS.
A protein called PEDF has been shown to halt excessive blood vessel growth in the eye, potentially treating diabetic retinopathy and macular degeneration. Researchers found that increasing PEDF levels could slow vision deterioration and prevent new vessels from overgrowing.
Researchers have identified a new mechanism for regulating gene expression that could help scientists understand developmental birth defects and other medical conditions. The TRA-1 protein plays a critical role in binding to DNA and controlling mRNA movement, which affects protein production during embryo development.
A study by Northwestern University and the Mayo Clinic found that postmenopausal hormone replacement therapy increases the risk for specific types of breast cancer with favorable prognoses, particularly invasive ductal or lobular carcinoma. The risk is higher among women who used hormone replacement therapy for five or fewer years.
Northwestern University researchers have identified key peptides that can halt and even reverse kidney disease in lupus. The peptides were found to be effective in delaying the onset of severe kidney disease in young mice and prolonging survival in adult mice with established kidney disease.
New study using GPS satellites tracks ground motions in Midwest seismic zone, revealing little to no motion across the area. The results suggest National Seismic Hazard maps should be revised to reflect lower estimates of earthquake risk, potentially leading to cost savings for new construction.
Astronomers have detected the first observational evidence for hypernova remnants in galaxy M101. The two remnants, MF83 and NGC5471B, are among the largest known supernova remnants and have X-ray luminosities about an order of magnitude brighter than brightest supernovae.
Researchers found that common soil minerals can work with ionizing radiation to break down toxic chlorinated chemicals into simpler compounds. However, this process may produce volatile gases, posing a risk of explosion at storage tanks like Hanford's.