Researchers at Northwestern University found that cells in the retina of fruit flies adopt mathematically predictable shapes and configurations, similar to soap bubbles. This discovery reveals a general principle of patterning found in a wide range of living things.
The grant will fund research on dopamine neurons and brain adaptation in Parkinson's disease, with the goal of developing new treatments for patients. Northwestern University's expertise in neuroscience and molecular imaging will be utilized in this effort.
Scientists discover endothelial cells have higher levels of receptors for endostatin, which protects melanoma cells from angiogenesis inhibitors. This finding may lead to new cancer therapies targeting both angiogenesis and tumor cell vasculogenic mimicry.
A study found that young women with favorable levels of cardiovascular risk factors have lower age-specific risks for cardiovascular disease and death. Among those at low risk, CHD and CVD cease to occur at epidemic rates.
A collaboration between pharmaceutical manufacturers, healthcare agencies, and researchers led to a significant reduction in epoetin-associated pure red-cell aplasia. The incidence decreased by 83% after improvements were made in storage and handling of the drug.
A team of engineers at Northwestern University has developed a method for precisely aligning multiple types of molecules on a silicon surface at room temperature. This breakthrough enables the construction of nanoscale systems such as molecular transistors or light-emitting diodes, and paves the way for integrating with current technol...
A new planned-care method for children with asthma has been shown to reduce symptoms by 13 days per year, need for rescue medication by a third, and improve adherence to medication as prescribed. The method involves regularly scheduled visits with specially trained nurses and extra education for physicians in asthma management.
A new study by Northwestern University researchers shows that social networks can efficiently lead to global organization, even with imperfect information transmission due to noise or error. The model is adaptable and robust, capable of responding to external conditions, and people tend to adjust their opinions based on the majority
A new hypothesis from Northwestern University researchers suggests that brain development and puberty could be key factors in learning disorders. The study found that individuals with learning problems develop more slowly than those without, and their brains stop developing around the time of puberty's onset.
Researchers developed a regulatable gene therapy that can be turned on and off using doxycycline, offering potential for treating Parkinson's disease. The treatment uses the glial cell line-derived neurotrophic factor (GDNF) protein to promote survival and differentiation of dopamine neurons.
Research suggests that filaments in the Galactic center are connected to areas of intense star formation, providing a link between thermal and non-thermal radio emission. The discovery sheds light on the phenomenon behind these striking features.
The prevalence of blood pressure control among hypertensive individuals declines with advancing age, particularly in women. According to the study, only 32% of men and 24% of women aged 80 and older had their blood pressure under control.
Researchers using GPS satellites have discovered a pattern of land movement across North America, with Canadian sites rising and US sites south of the Great Lakes sinking. This post-glacial rebound affects not only industries but also international water management.
Common in 18- to 30-month-old children, scale errors occur when youngsters try to perform actions on miniature objects despite knowing they're too small. The study suggests a failure of inhibitory control and immaturity of the prefrontal cortex.
A study by Northwestern University and the Framingham Heart Study found that parents with early-onset cardiovascular disease double the risk of heart attack or stroke in their children. Children with intermediate levels of risk factors are most affected, making parental cardiovascular disease a strong predictor of risk.
A new nanoscience-based diagnostic method called bio-bar-code amplification (BCA) has been developed, rivaling PCR in sensitivity and selectivity. BCA can detect as few as 10 DNA molecules in a sample in minutes, making it suitable for point-of-care diagnostics at various locations.
Women are more susceptible to lung cancer due to genetic mutations and hormonal changes, resulting in increased adenocarcinoma prevalence. Effective tobacco control measures are crucial to prevent a similar surge in lung cancer rates among women in developing countries.
Research by Mark Jung-Beeman and colleagues found increased neural activity in the right temporal lobe when solving problems with insight, suggesting a distinct computational and neural mechanism. This suggests that creative thinking relies on at least one unique brain process that involves reinterpretation and integration of information.
A study by Northwestern University found that over 90% of delinquent youth had experienced at least one traumatic event, with boys reporting higher rates than girls. The researchers recommend improving mental health services for high-risk youth and detecting post-traumatic stress disorder in juvenile detainees.
Researchers at Northwestern University successfully induced embryonic stem cells to develop into precursor bone marrow and blood cells in genetically mismatched mice. The technique could lead to a renewable alternative to donor bone marrow transplantation, reducing the risk of graft-versus-host disease.
A Northwestern University study found that COX-2 inhibitors can block lupus autoimmunity by targeting a specific molecular pathway. The researchers identified structural peculiarity in some COX-2 inhibitors as the key to their effectiveness, which may lead to the development of new treatments.
A Northwestern University study found that death rate after hospital discharge increased up to 72 percent for patients with DNR orders. Despite this, the researchers suggest that shorter lengths of stay can be achieved without compromising patient health through improvements in therapies and end-of-life care.
Research suggests that subconscious bias can distort facial perceptions, leading to the perpetuation of stereotypes and racism. Studies show that even well-meaning individuals may view identical faces as more hostile in African American faces, highlighting the importance of addressing implicit bias.
A recent study found a significant link between increased levels of C-reactive protein and colon cancer risk. However, the study's findings do not suggest that C-reactive protein is a definitive marker for colon cancer risk.
A recent study found that disabled children with psychosocial problems are less likely to receive mental healthcare, particularly younger and black children. In contrast, joint care coordination between a health professional and family member improved access to outpatient services.
Researchers developed ultrasound-guided liposomes to boost imaging and target drug/gene therapy. The technique directs liposomes to specific targets, such as atherosclerotic plaques or blood clots, and releases drugs with ultrasonic pulses, improving visualization and diagnosis of arterial conditions.
Researchers at Northwestern University have successfully grown nerve cells using an artificial three-dimensional network of nanofibers, a technique important in regenerative medicine. The innovative scaffold directs cell differentiation, driving neural progenitor cells to become neurons and not astrocytes.
Scientists at Northwestern University developed a method to construct flat or curved nanoscale structures using hybrid gold-polymer rods. The controlled assembly process holds promise for creating new materials with unique electronic and optical properties.
Researchers at Northwestern University have made a breakthrough in treating Alzheimer's disease by targeting the gene that causes memory loss. The study found that inhibiting an enzyme called BACE1 can prevent memory deficits and brain cell functional abnormalities in laboratory models of Alzheimer's disease.
A study published in The Journal of the American Medical Association found that fitness in young adulthood can significantly reduce the risk of developing high blood pressure, diabetes, and metabolic syndrome. Improving fitness levels by 50% or more can decrease these risks by as much as 50%.
Researchers found that elevated molecular chaperones promote longevity in C. elegans, a roundworm whose biochemical environment is similar to humans. This suggests that brief exposure to environmental and physiological stress can have long-term benefits to cells by unleashing molecular chaperones.
The study aims to identify new forms of therapy and hope for those at high risk of developing cancer. Six institutions will design and conduct experiments to test the cancer prevention potential of substances affecting various processes involved in cancer's formation and spread.
Researchers at Northwestern University found that leafy vegetables and herbs in Chicago residential gardens are highly likely to be contaminated with lead. The study's findings highlight the importance of testing soil lead levels and developing strategies to ensure safety for urban gardeners and their families.
The DEFINITE study found that implantable cardioverter-defibrillators (ICDs) can reduce the risk of sudden cardiac death and improve overall survival in non-ischemic cardiomyopathy patients. The study, which followed 458 participants for two years, showed a statistically significant reduction in arrhythmic deaths and all-cause mortality.
A study by Northwestern University researchers found that nearly a third of jailed teenagers have co-occurring substance abuse disorders and ADHD or behavioral disorders. The authors suggest that mental health professionals must collaborate with the juvenile justice system to improve screening, diversion, and access to treatment.
Researchers found that genetic factors play a significant role in coping behaviors, with females exhibiting inherited traits from their grandmothers. The study suggests that understanding the genetic basis of coping behaviors could help develop new treatments for psychiatric disorders.
A recent study published in the American Journal of Public Health found that major depression was most prevalent among Hispanics, followed by African Americans and whites. The odds of depressive disorders were significantly higher among older Hispanics due to caregiving responsibilities.
A molecular resonant tunneling device has been successfully realized, offering improved efficiency and reduced power consumption in computer architectures. The device, which works at room temperature and on silicon, holds promise for future applications in high-sensitivity sensors.
Primary progressive aphasia is a rare form of dementia that affects language abilities while preserving memory. Patients may struggle with word-finding and speaking, but can still recall recent events and maintain complex hobbies.
Researchers at Northwestern University found that imagining movement of affected limbs can improve stroke rehabilitation. The study used a motor imagery training program with patients experiencing hemiparesis, resulting in increased assessment scores and functionality.
A large study of nearly 44,000 healthy men found no association between dietary fat intake and stroke risk. The research suggests that saturated fat intake may actually be beneficial in reducing atherosclerosis, contrary to previous findings.
Researchers have created a new method that could detect diseases at earlier stages than possible now, using protein targets like PSA. The method is a million times more sensitive than conventional methods and has the potential to revolutionize cancer diagnostics and treatment.
Researchers identified a key process in malaria infection involving G proteins in red blood cells, which can be blocked with beta-blockers to prevent parasite entry. By targeting this process, new approaches for treating malaria may be developed using existing drugs.
Researchers at Northwestern University identified a molecular basis for the cell's detection of miniscule amounts of copper in bacteria. This discovery may lead to better methods for removing toxic metals from the environment and improving our understanding of diseases related to copper metabolism.
A Northwestern University team created a compound that inhibits death-associated protein kinase, reducing brain cell death after injury or stroke. The treatment has shown protection for up to six hours post-injury and can last for weeks.
A new study suggests that massive methane releases could have led to the extinction of up to 95% of marine species and 70% of land species. The researcher estimates that 10,000 gigatons of dissolved methane could have been released, causing catastrophic conflagrations and flooding.
Researchers have found small, soluble aggregated proteins called ADDLs in the brains of individuals with Alzheimer's disease, up to 70 times more than in normal individuals. These proteins may be reversibly blocking memory function, providing a potential target for new therapeutic drugs.
A new study by Northwestern University researchers reveals that nearly 80% of patients have a moderate or high genetic risk for adult-onset conditions. Using family history questionnaires and three-generation pedigrees, the team identified twice as many individuals at increased risk than documented in patient charts.
A comprehensive meta-analysis of 45 leadership studies found that women tend to use transformational leadership styles, which produce better worker performance and effectiveness. Women scored higher than men on one measure of transactional leadership and were more likely to be mentors and empower workers.
Researchers found that caspase cleavage of tau promotes the formation of abnormal filaments resembling tangles. This discovery provides a new link between amyloid-beta and tau tangles, suggesting a common cause for Alzheimer's disease.