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Penn State


How best to treat infections and tumors

A new mathematical analysis provides guidance for treating infections and tumors with drug resistance, suggesting that containment may extend effective life and improve patient outcomes in some cases. The study identifies two main factors influencing the choice between containment and aggressive treatment.

SourcePenn State·JournalPLOS Biology·DateFeb 9, 2017

Deep groundwater aquifers respond rapidly to climate variability

Researchers found that responses to climate variations can be detected in deep groundwater aquifers within a year, suggesting an intermediate connection between precipitation and groundwater levels. Pumping of aquifers may drive this rapid response, controlled by crop water demand and agricultural industry activities.

SourcePenn State·JournalNature Geoscience·DateFeb 8, 2017

Campus natural gas power plants pose no radon risks

A two-year study found that Penn State's power plants on campus pose no radon-related health risks, despite high concentrations of radon in the natural gas used. Researchers measured radon levels downwind and upwind from the plants, finding them to be far below a health threat.

SourcePenn State·JournalJournal of the Air & Waste Management Association·DateFeb 6, 2017

Researchers develop new compound to fight cytomegalovirus

Researchers develop a Retro94-based compound that effectively stops CMV from making copies of itself, providing a potential effective and safe therapy against human CMV. The treatment could protect immunocompromised patients with active CMV infection or prevent reactivation in the body.

SourcePenn State·JournalJournal of Virology·DateJan 10, 2017

An ecological invasion mimics a drunken walk

A new mathematical model describes ecological invasions as a random walk, categorizing randomness into spatial, demographic, and temporal factors. The model replicates key properties observed in computer simulations, resolving an ongoing argument between ecologists and mathematicians.

SourcePenn State·JournalTheoretical Population Biology·DateJan 9, 2017

Deepest X-ray image ever reveals black hole treasure trove

A team of astronomers led by Penn State's Niel Brandt has captured the deepest X-ray image ever obtained, revealing a treasure trove of supermassive black holes. The image, taken with Chandra observing time of about 11 weeks, shows that these massive objects grow in bursts rather than slowly accumulating matter.

New technique uses immune cells to deliver anti-cancer drugs

Researchers at Penn State have developed a novel biodegradable nanoparticle-based system that utilizes immune cells to target and deliver cancer-fighting drugs directly to tumors. This innovative approach combines the body's natural immune response with targeted delivery, showing promise for effective treatment of various cancers.

SourcePenn State·JournalSmall·DateJan 4, 2017

New approach captures the energy of slow motion

A new concept harnesses low-frequency mechanical energy to generate electricity, improving performance at lower frequencies than existing devices. The device, called an ionic diode, operates at one-tenth Hertz and has a higher peak power density compared to piezoelectric generators.

SourcePenn State·JournalAdvanced Energy Materials·DateDec 21, 2016

Stressed snakes strike first

A team of scientists led by Mark Herr found that cottonmouths with high baseline levels of corticosterone were more likely to strike during encounters. The study suggests that protecting snake habitats may reduce the incidence of snakebites and that a snake's striking behavior is related to its baseline level of stress.

SourcePenn State·JournalGeneral and Comparative Endocrinology·DateDec 21, 2016

Workplace fun is fundamental for learning on the job

A study found that having fun at work is significantly related to informal learning, which includes unstructured forms of learning. Fun activities supported by management enhance wellbeing and create a safe environment for learning. Managers' support for fun matters more than their support for learning.

SourcePenn State·JournalJournal of Vocational Behavior·DateDec 13, 2016

Key regulator of bone development identified

Researchers at Penn State University have identified Speckle-type POZ Protein (Spop) as a key regulator of bone development. The study reveals that Spop positively regulates Hedgehog signaling during bone formation, leading to reduced bone density and brachydactyly-like symptoms.

SourcePenn State·JournalProceedings of the National Academy of Sciences·DateDec 8, 2016

Oxygen can wake up dormant bacteria for antibiotic attacks

A team of researchers has identified an oxygen-dependent toxin antitoxin system that can be targeted to inhibit biofilm formation and combat antibiotic-resistant bacteria. By understanding the molecular mechanisms behind this system, scientists hope to develop more effective antimicrobials.

SourcePenn State·JournalNature Communications·DateDec 8, 2016

Corals much older than previously thought, study finds

Researchers have estimated that elkhorn coral genotypes in Florida and the Caribbean are up to 5,000 years old, making them potentially the longest-lived animals. This study uses a genetic approach to estimate coral ages, which may provide hope for their survival under climate change.

SourcePenn State·JournalMolecular Ecology·DateNov 30, 2016

Adding higher frequencies helps detect adolescent hearing loss

Adding higher frequencies to the American Academy of Pediatrics hearing test protocol helps detect adolescent hearing loss. Early detection enables modification of behavior to prevent continued damage. The study found that young adults with mild hearing loss may exhibit reading, emotional, or socialization problems.

SourcePenn State·JournalJournal of Adolescent Health·DateNov 21, 2016

Fear of gaining weight may influence contraception choices

Women who are overweight or obese are less likely to use hormonal birth control methods, opting for long-acting reversible contraceptives (LARCs) like IUDs and implants instead. This preference is driven by fear of weight gain associated with the pill and shot, despite LARCs not containing estrogen.

SourcePenn State·JournalContraception·DateNov 17, 2016

Cosmic whistle packs a surprisingly energetic punch

Fast radio bursts (FRBs) emit non-radio emission, challenging models and suggesting severe consequences for host galaxies. The discovery of FRB 131104's gamma-ray counterpart opens possibilities for detecting long-lived counterparts using X-ray, optical, and radio telescopes.

SourcePenn State·JournalThe Astrophysical Journal Letters·DateNov 10, 2016

New strategy for antidepressant therapies

Researchers at Penn State have discovered a new strategy for antidepressant therapies by increasing the activity of the neurotransmitter GABA in the brains of depressed mice. This approach shows promise as a rapidly acting and more effective treatment option.

SourcePenn State·JournalMolecular Psychiatry·DateNov 8, 2016

Words matter when talking about Alzheimer's

Researchers suggest shifting from 'curing' Alzheimer's to building resilience, acknowledging the disease is intertwined with aging processes. They propose education, infrastructure support and proper care as key components of societal response.

SourcePenn State·JournalThe American Journal of Bioethics·DateNov 3, 2016