A new database collects results from the antiSMASH tool to ease comparison of thousands of bacterial genomes when it comes to metabolites. The database contains 6,200 full bacterial genomes and allows users to quickly access precomputed results.
Engineers boosted cells' ability to produce unsaturated lipids, leading to increased membrane respiration and growth rate. This knowledge could improve biofuel production and develop new treatments for diseases like type 2 diabetes.
Researchers at DTU Bioengineering have developed a high-tech antivenom against black mamba venom using human antibodies, which can potentially save thousands of lives annually. The breakthrough antivenom uses a biotechnological method to discover human antibodies, allowing for large-scale production and industrial use.
A novel nano material with electrical and magnetic properties has been synthesized by researchers at DTU Chemistry. The material, Chromium-Chloride-Pyrazine, is an organic/inorganic hybrid with promising prospects for quantum computing, superconductors, catalysts, batteries, fuel cells, and electronics.
A new study introduces CasPER, a CRISPR/Cas9 method that diversifies enzymes without additional engineering. It enables the efficient integration of large DNA fragments, allowing for hundreds of thousands of enzyme variants to be generated.
A European project aims to make pheromones an affordable alternative to conventional insecticides. Researchers are developing biotechnology-based pheromone production to reduce costs and environmental impact. The goal is to protect crops from pests like the fall armyworm, which poses a major threat to food security.
A new study has revealed that the bedrock below West Antarctica's ice sheet is rising at an unprecedented rate, suggesting a much more fluid Earth mantle than previously believed. This discovery could impact our understanding of climate changes in Antarctica and have significant implications for global sea levels.
A new ultra-deep DNA sequencing approach uncovers competing mechanisms of evolution as a threat to efficient large-scale fermentation. Evolution constrains bioproduction, leading to yield decrease and productivity issues.
A new study suggests that cells can be engineered to overcome evolutionary pressure and stably produce high levels of valuable chemicals by rewiring production cells to slow down growth when they lose production. This allows productive cells to maintain their function even in large-scale fermentations.
Scientists have developed a new method to rank the risk of resistance genes in bacteria, allowing for better prediction of antibiotic evolution and development. By analyzing 200 genes, researchers identified key factors influencing gene transfer and integration into new hosts.
Scientists have discovered predictable sensitivities to other classes of antibiotics in Pseudomonas infections, paving the way for personalized treatment strategies. The findings suggest that targeting specific mutations could lead to more effective treatments for cystic fibrosis patients.
A new study in Nature Communications reveals the link between exploding stars, clouds, and climate on Earth. The research shows that atmospheric ions produced by cosmic rays accelerate the growth of aerosols into cloud condensation nuclei, influencing cloud formation and climate.
A large Danish study found that whole grains reduce inflammation in the body and lead to weight loss in overweight adults. The study suggests that choosing whole grains over refined grains can have numerous health benefits, particularly for individuals at risk of cardiovascular disease or type 2 diabetes.
Jens Nielsen's groundbreaking work in systems biology and engineering has earned him a gold medal from the Royal Swedish Academy of Sciences. His research focuses on developing efficient cell factories for sustainable production of fuels and chemicals, with implications for a more sustainable lifestyle.
Jens Nielsen, Scientific Director at the Novo Nordisk Foundation Center for Biosustainability, received the ENI Energy Frontiers Award for his groundbreaking research on producing fuels and chemical products from renewable sources. The award recognizes his work on engineering microorganisms to open new solutions for biofuel production.
Researchers at Technical University of Denmark discover that resistance genes originate from the same group as antibiotics, Actinobacteria. The study reveals a new mechanism called 'carry back', where pathogens acquire genes through a primitive form of bacterial sex.
During solar storms, large bursts of electrons are sent into the ionosphere, but surprisingly, they also remove electrons from large areas. This phenomenon is triggered by the interaction between the Sun's magnetic field and the Earth's magnetic field, creating unstable areas in the ionosphere that can disrupt navigation systems.
A new method called poreFUME can rapidly detect resistance genes in gut bacteria, leading to improved treatment outcomes. The study found the method to be 97% accurate and significantly cheaper than current methods.
Researchers explore electrocatalysis to transform atmospheric molecules into useful products, such as hydrogen and chemicals, for a sustainable future. Effective catalysts are needed to drive the process, but advancements in theory and experiments hold promise.
Researchers from DTU Biosustain have engineered E. coli cells to produce large amounts of serine, a compound used in detergents and pharmaceuticals. The cells can tolerate high concentrations of serine and produce up to 250-300 grams per kg of sugar added.
A new computational model describes the metabolism of Chinese hamster ovary cells (CHO), enabling comprehensive simulations to optimize protein production. The iCHO1766 model has been tested with high accuracy, promising to reduce the cost and increase the availability of biotherapeutic proteins.
Researchers from DTU Physics demonstrated how quantum-engineered states of light can improve the efficiency of feedback cooling beyond classical bounds. They successfully cooled a mechanical oscillator's temperature by more than 140 degrees below room temperature using a novel technique involving squeezed light.
VILLUM FONDEN awards $150 million grant to establish a new research centre at Technical University of Denmark, focusing on developing sustainable fuels and chemicals. The centre will be led by Professor Ib Chorkendorff and aims to contribute to the green transformation of global society.
A nanotechnology breakthrough from DTU allows printing of high-resolution data and colour images at 127,000 DPI, comparable to weekly magazines.
A PhD project from the National Food Institute found that certain genetic variations increase the risk of lower vitamin D levels in Danes. The study identified two genes, CYP2R1 and GC, as influencers of vitamin D status. Genetic predisposition may be used to identify individuals at risk of lower vitamin D levels.
Researchers at DTU Systems Biology have developed a new diagnostic technology, TumorTracer, which identifies the source of cancer with 85% certainty. The method uses advanced self-learning computer algorithms to analyze DNA mutations in cancer tissue samples.
New Danish research reveals that wastewater treatment plants contain a vast pool of genes providing bacteria with antimicrobial resistance, but these genes are rarely found in hazardous bacteria. The study challenges the common perception that wastewater treatment plants are hotbeds for the spread of antimicrobial resistance genes.
Researchers analyzed toilet waste from international flights to identify disease-causing microorganisms and resistance genes. The study found geographical differences in resistance genes and microorganism prevalence, highlighting the potential for airports as global surveillance sites.
Scientists at DTU Physics successfully captured protein quakes that dissipate solar energy throughout entire protein molecules, validating a long-standing hypothesis. This breakthrough has implications for harnessing solar energy in solar cells and other light-absorption systems.
Researchers recommend using fluorochemicals only where absolutely essential, citing links to cancer, immune system damage, reproductive issues, and environmental contamination. They urge producers to test alternatives properly before market release.
Researchers have mapped 500 unknown microorganisms in human intestines and 800 bacteriophages that attack them. This new understanding could lead to more targeted treatments for diseases like type 2 diabetes, asthma, and obesity.
A new study found that breastfeeding promotes the development of beneficial bacteria in babies' guts, which may help prevent obesity, allergies, and other diseases later in life. The study, led by Professor Kim F. Michaelsen, examined gut microbiota in 330 Danish children over three years.
A Danish experiment, SKY2, shows that cosmic rays enhance cloud condensation nuclei formation, contradicting conventional chemical theory. The study suggests a new chemistry process supplying extra molecules to keep clusters growing, boosting the theory of cosmic rays' direct involvement in weather and climate.