The article outlines five complementary actions to increase electrification rates and secure long-term access to affordable energy in Africa. Key findings include the need for an independent champion to transform the sector, international partnerships, and investment in clean energy.
Researchers successfully engineered yeast to produce spermidine, a natural molecule that induces autophagy, in hopes of addressing age-related diseases. The production yield reached 2.3 grams per liter, paving the way for fermentation-based manufacture of polyamines and their analogues.
A recent study by the National Food Institute found that clotrimazole, an over-the-counter fungicide, can significantly alter sex hormones in pregnant rats and their developing fetuses. This exposure was observed at concentrations comparable to those experienced by human mothers taking clotrimazole to treat vaginal thrush. The research...
A team of bioengineers defined ten overarching classes of constraints on early metabolic networks based on basic chemistry and physics. These abiotic constraints dictate fundamental aspects of chemical processes, influencing the evolution of alternative transport systems and stress response mechanisms.
Researchers have developed CareGum, a green and recyclable sensor material that can monitor motor impairment associated with neurological disorders. The material offers stretchability, self-healing capacities, and electrical conductivity, allowing for personalized bioelectronics and real-time monitoring of movements.
A new mathematical model predicts Clostridium botulinum growth and toxin production in chilled food products, reducing the need for costly laboratory experiments. The model's comprehensive approach considers multiple factors, including storage temperature, pH, salt, and preservatives, to ensure food safety.
Physicists at DTU have developed a microscopic harvester controlled by AI, eliminating the need for chemical and mechanical processes. The technology can extract valuable substances directly from plant cells, reducing pollution and costs.
Researchers developed natural lactic acid bacterium that secretes antimicrobial peptide nisin, extending food shelf life and reducing waste. Nisin is approved for use in various foods to prevent spoilage and foodborne illness.
Research from DTU found that young people experience better work-life balance, but more uncertainty about their work. Managers report higher efficiency and less lack of important work tools compared to employees. The six factors can help organizations understand how to promote efficiency and well-being when working from home.
Scientists found that certain bacteria, like Lactobacillus amylovorus, can increase fermentation yields by up to three percent. This discovery suggests a new approach to industrial production, focusing on selecting beneficial bacteria rather than relying on broad-spectrum antibiotics or treatments.
Researchers identified 126 substances that can harm children's health, including phthalates, flame retardants, and fragrances. The study recommends prioritizing phase-out of these chemicals and developing benchmarks for safe use in toy materials.
Researchers developed an in vitro and computational model-based approach to identify chemicals affecting male reproductive health without animal tests. The method predicts exposure of fetuses to harmful substances, showing promising results compared to traditional animal tests.
Researchers developed a new method to predict epidemic development, which considers both best and worst-case scenarios. This approach provides a more realistic estimate of the epidemic's severity, helping policymakers make informed decisions.
Researchers developed a groundbreaking model that defines new geographical scales from mobile tracking data, bringing geography back to understanding of mobility. The model identifies typical distances and choices corresponding to geographical boundaries, varying by individual characteristics.
Researchers at Technical University of Denmark have isolated new strains of lactic acid bacteria that can increase the safety of fermented camel milk products. The bacteria can kill off disease-causing microorganisms such as E.coli and salmonella, making the milk safer for consumption.
Researchers found that butylparaben, used in cosmetics, has endocrine disrupting effects on humans. The study proposes using the existing EU guidance document with modifications to identify endocrine disrupting effects of a broader spectrum of chemicals.
Campylobacter cases increased by 18.5% in Denmark, mainly attributed to outbreaks related to chicken meat. The study highlights the need for better controls on campylobacter in food production chains and emphasizes the importance of reliable data for effective prevention measures.
Researchers developed a machine learning predictive model to predict nephrotoxicity risk in testicular cancer patients using Danish patient data. The model correctly predicted 67% of high-risk patients and 92% of low-risk patients who did not develop nephrotoxicity.
Researchers discovered a correlation between needle or sting length and diameter to ensure strength and elasticity in pointed objects. The study's findings have the potential to optimize syringe needle design and reduce material consumption in nail production.
Researchers at the Technical University of Denmark have developed a new design for bridge girders that uses topology optimization to minimize steel use while maintaining strength. The design could lead to weight reductions of up to 28% and corresponding CO2 emissions savings of up to 20%.
A new research-based framework helps companies balance economic and sustainability factors when producing biochemicals. The framework assesses the true sustainability of biochemicals by combining economic and environmental impacts into a monetary single score.
Researchers have discovered a new way that plants regulate volatile isoprenoid emissions, which contribute to hydrocarbons released into the atmosphere. This knowledge could lead to optimizing forest land and farming areas by planting fewer high-emitter-plants and more zero-emitters.
Researchers have discovered an enzyme that converts low-cost sugars into hard-to-produce alpha-GalNAc sugars with therapeutic properties, particularly relevant for cancer vaccines. The enzyme, GH109, has anti-cancer qualities and can be optimized for large-scale production.
Scientists at DTU Biosustain successfully produced psilocybin de novo in yeast, eliminating the need for expensive substrates and enabling large-scale fermentation. This breakthrough could pave the way for the commercial production of psilocybin as a potential treatment for depression and other psychological conditions.
A new study introduces Memote, a community-maintained tool to assess and improve metabolic models. It addresses issues such as annotations, conceptual integrity, and experimental validation, promoting openness and collaboration among researchers.
Researchers from the Technical University of Denmark have discovered a way to improve EPO production by knocking out specific genes in Chinese Hamster Ovary cells. This results in a 1.4-fold increase in production and significantly improved product quality, with up to 40% of the most active EPO form produced.
Researchers have found that natural antioxidant L-ergothioneine can relieve some clinical symptoms of Pre-eclampsia in rats, including reduced blood pressure and fetal growth restriction. Further study is needed to validate its safety and efficacy in humans.
A global surveillance system for antimicrobial resistance can be established through genomic analysis of sewage, providing valuable information about the types of bacteria present in specific areas. This approach has great potential as a tool for monitoring diseases and managing outbreaks globally.
A young student at DTU Space has demonstrated that global sea level rise has accelerated over the past four decades using data from European satellites. The new research supports previous studies and provides a more comprehensive picture of the global rise in sea levels.
Researchers used Life Cycle Assessment to identify environmental hotspots in the production of lactic acid, a key bioplastic. The study found that heavy solvent usage and black energy consumption can negatively impact sustainability. Additionally, the development phase is crucial for identifying and addressing these hotspots.
Researchers at DTU Biosustain successfully produced 0.6g/L of ergothioneine in yeast broth, a promising antioxidant with neuroprotective effects. The production method could lead to cheaper and more accessible supplements, addressing high market prices due to chemical synthesis costs.
Researchers demonstrate the production of a wide range of sulfated aromatic compounds, including antifouling agents and pharmaceuticals, using microbial hosts. The process enables the large-scale production of sulfated phenolic compounds, offering potential applications in medicine, nutraceuticals, and other industries.
Scientists at DTU Physics have created a two-dimensional lattice structure of 30,000 entangled light pulses, paving the way for less expensive and more powerful quantum computers. This breakthrough uses room-temperature materials and avoids the need for costly refrigeration technology.
CRISPR-BEST addresses the challenge of genetic instability caused by double-stranded breaks in genome editing. The new tool creates mutations in actinomycetes without DNA breakage, enabling efficient targeting of genes for bioactive compound production.
Researchers found that certain transporter proteins, such as MAE1 from Schizosaccharomyces pombe, can improve the secretion of dicarboxylic acids in baker's yeast with minimal energy expenditure. Building a comprehensive library of transporters will enable more efficient strain development and precise drug development.
A new study identifies key transport proteins that facilitate the uptake of human milk oligosaccharides, crucial for developing a healthy infant gut microbiota. The researchers have established a framework to map the best sugars in mother's milk on the menu of infant health-beneficial gut bacteria.
Researchers have discovered that microorganisms can shift from fermentation to respiration, producing more internal energy and reducing unwanted byproducts. This breakthrough enables the design of new, improved cell factories with enhanced efficiency.
Researchers at Technical University of Denmark have developed a method to quickly couple enzymes with specific methylation patterns, revealing which enzymes are responsible for certain patterns. This discovery holds great promise for improving DNA transformation and introducing foreign DNA into host organisms.
Researchers have created a super-stable form of MHC tetramer reagent, enabling faster detection and manipulation of T cells in patients. This breakthrough opens new possibilities for personalized cancer treatment strategies.
Experimental studies of electrochemical ammonia synthesis are flawed, lacking proper protocols to rule out contamination and ensure accurate results. A new study in Nature proposes a method using Nitrogen-15 isotope labeling to separate true N2 reduction from spurious contamination.
The study found that replacing red and processed meat with fish in the Danish diet can lead to a significant health benefit, particularly for men over 50 and women of childbearing age. The greatest effect is seen when consuming fatty fish, as it contains healthy fatty acids and vitamin D.
Scientists at Technical University of Denmark have discovered 9 genes that can be silenced to increase protein production in engineered yeast cells by 2.2-fold. This breakthrough method has significant implications for industries producing biopharmaceutical proteins and industrial enzymes.
A new study in Nature Communications finds that the collective attention span is narrowing, with increasingly steep gradients of attention given to each cultural item. The accelerating vicissitudes of popular content are driven by the rapid exhaustion of limited attention resources, as suggested by a mathematical model with three basic...
Researchers have successfully produced mammalian cell lines that can produce human glycosylation profiles for Alpha-1-antitrypsin proteins. This breakthrough enables the production of recombinant Alpha-1-antitrypsin without dependency on human donors, reducing treatment costs and improving patient outcomes.
A comprehensive analysis of sewage from 74 cities in 60 countries has yielded comparable global data on antimicrobial resistant bacteria. The study found that North America, Western Europe, Australia, and New Zealand have low levels of antimicrobial resistance, while Asia, Africa, and South America have high levels.
New study finds that within two to three years after first infection, Pseudomonas aeruginosa bacteria adapt rapidly, growing slower and optimizing fitness to survive. Clinicians can monitor bacterial traits such as attachment to surfaces and aggregation in biofilms to detect early chronic infections.
Scientists at DTU have discovered that a combination of mecillinam and cefotaxime can eliminate multi-drug resistant E. coli causing urinary tract infections. This novel approach could become an effective measure against antibiotic resistance, offering new hope in treating this common infection.
A team of researchers from Denmark has successfully created a graphene-based nanoscale electronics by encapsulating graphene inside hexagonal boron nitride. The new technique allows for the control of graphene's band structure, enabling the design of components and devices with precise electrical properties.
Scientists have identified four new anti-CRISPR proteins that can regulate CRISPR-Cas9 systems better. These proteins were found in soil and human gut samples, suggesting they are widespread in nature.
A new EU Horizon 2020 project aims to produce therapeutic substances in baker's yeast, providing an eco-friendly alternative to traditional methods. Researchers will map the biosynthetic pathways of Indian snakeroot to create a sustainable production route.