The Endocrine Society recommends large randomized controlled trials to test vitamin D's effects on chronic diseases such as autoimmunity, obesity, diabetes, hypertension, and heart disease. Topical and oral vitamin D may be useful in treating skin disorders like psoriasis, but more research is needed.
A recent study suggests that pleasure eating can activate the body's reward system, leading to overeating. Researchers found that the hormone ghrelin and chemical compounds like 2-arachidonoylglycerol increased during hedonic eating, overriding the body's signal that enough has been eaten.
Researchers found women who smoke and carry certain gene variants are more likely to experience hot flashes. The study suggests that these women may benefit from aggressive smoking cessation efforts.
Researchers discovered that low adrenomedullin levels may contribute to slower muscle contractions and ciliary beating, favoring embryo retention in the oviduct. Administering adrenomedullin reversed this effect, suggesting it could be a useful predictor for tubal ectopic pregnancy.
A recent study published by The Endocrine Society reveals that heavier female babies are more likely to develop diabetes and related metabolic risks when they grow up compared to their male counterparts. The study found a significant association between birth weight and body fat distribution in early childhood with future metabolic ris...
A new study has found that consuming a vitamin D-fortified yogurt drink can improve inflammatory markers in patients with type 2 diabetes, reducing the risk of coronary heart disease and stroke. Additionally, extra calcium in the fortified drink may confer additional anti-inflammatory benefits.
A recent study found that low doses of endocrine-disrupting chemicals can result in significant health effects, contradicting current testing paradigms. Researchers recommend expanded and generalized safety testing to detect potential adverse effects of these chemicals.
A recent study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that elderly thyroid surgery patients are at a higher risk for serious complications. The study examined 7,915 patients from the American College of Surgeons National Surgical Quality Improvement Program database and found that elde...
A recent study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that elderly people with the metabolic syndrome are at a higher risk of chronic kidney disease. Insulin resistance and high blood glucose levels were also linked to rapid decline in renal function.
A recent study found that vitamin D deficiency is associated with increased mortality in female nursing home residents. The study, published in the Journal of Clinical Endocrinology and Metabolism, examined 961 nursing home residents and found that 92.8% were deficient in vitamin D.
A recent study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that intermittent exercise with low oxygen concentrations significantly improves glycemic control in patients with type 2 diabetes. Exercise under hypoxic conditions provides greater improvements than intermittent exercise alone.
A recent study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that heart failure is associated with a 30% increase in major fractures. Researchers identified a high-risk population benefiting from increased screening and treatment for osteoporosis.
The Endocrine Society releases a clinical practice guideline recommending that all hospitalized patients, regardless of diabetes status, have their blood glucose levels tested. This can help prevent complications and mortality associated with hyperglycemia in non-critically ill patients.
A recent study identified effective agents from approved drugs with anti-cancer activity in thyroid cancer cells, offering potential repurposing opportunities for aggressive recurrent or metastatic cases. The compounds found had potent activity across different therapeutic categories and modes of action.
A recent study found that low vitamin D levels are significantly more prevalent in obese children and associated with risk factors for type 2 diabetes. Poor dietary habits such as skipping breakfast and increased soda and juice intake were also linked to lower vitamin D levels.
A recent study found that resting muscle sympathetic nerve activity (MSNA) is a significant independent predictor of weight-loss outcome in overweight or obese subjects. Successful weight losers demonstrated large increases in nerve activity following a carbohydrate test meal.
A study found that consuming dairy foods and higher protein resulted in improved markers of bone formation and reduced markers of bone degradation in overweight premenopausal women. The study showed that a diet with a high proportion of dairy foods and higher than recommended protein intake was associated with improved bone health.
A recent study found that a childhood dietary intervention resulted in significantly lower fasting plasma glucose levels and systolic blood pressure in young adulthood. The study suggests that reducing fat and increasing fiber intake during childhood may have long-term benefits for chronic diseases like diabetes and heart disease.
A recent study published in the Journal of Clinical Endocrinology & Metabolism found that higher levels of testosterone were associated with reduced loss of lean muscle mass in older men. Higher testosterone levels were also linked to less loss of lower body strength, particularly in those who were losing weight.
A clinical practice guideline recommends continuous glucose monitoring for type 1 diabetes patients who can use devices daily, while also limiting risks of hypoglycemia. The guideline aims to improve glycemic control and reduce hypoglycemia risk in patients with type 1 and type 2 diabetes.
A recent study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found a link between shift work and increased cortisol levels. This association was discovered in individuals working shifts at a young age and may contribute to cardiovascular risk.
Perinatal exposure to BPA may alter long-term hormone response and increase predisposition to breast cancer. Researchers found that BPA-exposed female mice had an increased response to progesterone and a higher cell number in their milk ducts.
A recent study found that heavier women have fewer hot flashes than their leaner counterparts after menopause. The inverse association between body size and hot flashes was observed only among older women, suggesting that age plays a significant role in this relationship.
A recent study found that postmenopausal women who smoke have higher androgen and estrogen levels than non-smoking women. Smoking cessation appears to reverse this effect, suggesting a potential mechanism by which tobacco smoke influences chronic disease risk through hormonal mechanisms.
A recent study found that higher muscle mass is associated with better insulin sensitivity and lower risk of pre- or overt diabetes. Building muscle may be a key factor in improving metabolic health, particularly for overweight individuals who struggle to lose weight.
A recent study found that consuming high fructose corn syrup increases cholesterol and triglycerides, key indicators of heart disease risk. The study suggests the current upper limit of sugar consumption may need re-evaluation.
A recent study found that early treatment with the diabetes drug metformin may prevent or delay the development of polycystic ovary syndrome (PCOS) in adolescents. The study, which compared early versus late metformin treatment, showed that early therapy prevented PCOS symptoms more effectively than late treatment.
A new animal study finds that a high-fat diet can cause inflammation and injury to brain cells in the hypothalamus, leading to weight gain. The research suggests that this neuronal injury may be permanent, contributing to the difficulty of achieving sustained weight loss in obese individuals.
A new study by Teresa Pinto and colleagues reveals that teens with Type 2 diabetes exhibit early signs of diastolic dysfunction, a condition where the heart struggles to fill with blood between beats. The study found that these impaired hearts show reduced cardiac output during exercise, which may be reversible with physical activity.
A new study found that fetal exposure to BPA changes the development of the uterus in female primates. The research suggests that oral and subcutaneous forms of BPA can alter gene expression and affect uterine cell development.
A new study finds that pregnant women who gain too much weight are more likely to have newborns with high body fat, regardless of pre-pregnancy weight. This increased obesity risk exists even when birth weight is normal and may be associated with higher childhood obesity rates.
A new study published by The Endocrine Society finds that testosterone levels do not decline with age in healthy older men. In fact, serum testosterone levels remained stable across the board, indicating that age is not a contributing factor to declining testosterone levels.
A new study found that overweight girls who consumed sugar-free, low-fat desserts several times a week lost more weight and had better blood pressure control compared to those who ate dessert once a week. The low-glycemic index desserts also improved appetite-suppressing hormone levels and insulin resistance markers.
The Endocrine Society released a clinical practice guideline recommending vitamin D screening and dietary intakes for children and adults at risk of deficiency. Key findings include recommended daily intake ranges, from 400 IU/day for infants and 600 IU/day for adults, to prevent vitamin D deficiency.
A large population study found that gestational diabetes does not increase cardiovascular risk in all women, but may pose a higher risk to Hispanic women, with a 70% increased likelihood of developing heart disease compared to their non-diabetic counterparts.
A recent study comparing yo-yo dieting to lifelong obesity found that weight fluctuations are better for health than remaining obese. Mice on a yo-yo diet regimen lived nearly 35% longer and had improved health measures compared to those on a high-fat diet.
Researchers found that women with low bone density are seven times more likely to benefit from bisphosphonate drugs when their vitamin D levels are above the recommended threshold. Maintaining adequate vitamin D levels is crucial for optimizing osteoporosis treatment, particularly in postmenopausal women.
A lower dose of zoledronic acid has been found to increase bone density and decrease bone resorption, potentially reducing the risk of osteoporotic fractures. The study suggests that a one-fifth or one-half of the recommended dose may be sufficient for this effect.
A new study published by The Endocrine Society reveals that women with higher levels of the hormone leptin experience fewer symptoms of depression. This finding suggests that leptin may have antidepressant qualities and is independent of body mass index (BMI).
A new study suggests that daily testosterone therapy can improve verbal learning and memory in postmenopausal women, reducing their risk of cognitive decline. The research found significant benefits after six months of treatment.
A new multicenter study found that delaying intravenous (IV) feeding in critically ill patients who cannot tolerate tube feeding can enhance recovery and reduce complications. The study, which contradicts European guidelines, recommends waiting a week before initiating IV feeding to avoid hyperglycemia.
A new study suggests that a modest reduction in carbohydrate consumption can promote loss of deep belly fat, even with little or no weight change. The study, which involved 69 overweight but healthy individuals, found that those on a moderately carb-restricted diet lost more total body fat during a weight loss phase.
Researchers discovered large amounts of brown fat in adults and found it can be grown in labs, burning substantial calories. The discovery suggests brown fat could be used to treat obesity and diabetes, but cannot replace traditional approaches.
A new targeted therapy, G-1, has been shown to halt the growth of tumors in animals with advanced prostate cancer resistant to hormone therapy. The treatment works by targeting and activating protein GPR30, which sensitizes tumor cells to its inhibiting effects.
A new therapeutic vaccine targets ghrelin to suppress appetite and increase energy expenditure in mice, reducing food intake by up to 82% after a single vaccination. The study suggests an alternate treatment approach for obesity that can be used in combination with diet and exercise.
A recent study has linked subclinical hyperthyroidism in elderly individuals to a significantly increased risk of death. The research found that those with this condition were 65% more likely to die during a six-year follow-up period than those with normal thyroid function.
A hormone test measuring anti-Mullerian hormone (AMH) levels can predict a woman's ovarian function after chemotherapy for breast cancer. Women with low AMH levels before treatment are more likely to experience infertility due to chemotherapy-induced damage.
A low-cost healthy lifestyle program, including self-weighing weekly or monthly, has been shown to prevent excessive weight gain in pregnant women with pre-existing overweight. Regular monitoring of weight gain and simple health messages can reduce pregnancy complications, such as gestational diabetes and birth complications.
A new study suggests that weight loss due to bariatric surgery may reduce the risk of Alzheimer's disease by lowering the expression of genes related to the condition. After a significant weight loss, patients showed a 22% decrease in amyloid precursor protein expression and a 31% decrease in messenger RNA for APP.
Researchers developed a stem cell treatment enriched with insulin-like growth factor-I (IGF-I) to mend non-healing bone fractures. The study showed that the treated cells became bone cells and helped repair fractures in animal models.