Researchers create engineered mesoporous silica nanoparticles that improve drug delivery to tumors, increasing particle retention by up to 10% and reducing systemic side effects. The optimized platform achieves significant increases in doxorubicin delivery, inducing tumor shrinkage and apoptosis while improving safety profiles.
Researchers at UCLA have created a lens-free optical microscope that can produce high-resolution 3D images of microscopic objects. The system uses tomography and digital sensor arrays to capture detailed sub-cellular structures without using a lens.
Researchers at UCLA develop a new method for targeted drug delivery using nanotechnology. They demonstrate the ability to package drug-loaded 'nanodisks' into vault nanoparticles, which can hold hundreds of drugs and target specific cells in the body.
Researchers at UCLA have made a breakthrough in controlled engineering of nanocatalysts by using surfactants and biomolecules to produce predictable shapes. This innovation has the potential to improve catalytic properties and lead to more efficient energy production and reduced pollution.
Scientists have discovered ancient mollusk fossils that may indicate how warm the planet will become if carbon dioxide levels are stabilized at current values. The findings suggest summertime Arctic temperatures could increase by 2-5 degrees Fahrenheit, leading to a permanent ice cap melting and further heating the planet.
Researchers at UCLA developed a 'roadmap' of complex signaling processes in cancer that could lead to new methods for diagnosing and overcoming drug resistance. The study identifies points of susceptibility that can be targeted by 'cocktail' therapies to prevent drug resistance.
Physicists at UCLA found that dividing space into discrete locations like a chessboard explains how point-like electrons manage to carry their intrinsic angular momentum. This concept, inspired by graphene's electronic properties, proposes that space at very small distances is segmented, rather than smooth.
Researchers found that combining tai chi with standard treatment for depressed elderly adults led to greater improvement in depression levels and quality of life. Participants who took escitalopram and participated in tai chi showed higher remission rates than those receiving health education.
A recent study found that patients' mortality risk increases with nurse staffing shortfalls, particularly when nurses' workloads increase due to high patient turnover. The research analyzed nearly 198,000 admitted patients and 177,000 nursing shifts across 43 patient-care units at a large hospital.
Researchers at UCLA's Henry Samueli School of Engineering and Applied Science have developed a way to produce normal butanol — often proposed as a
Researchers at UCLA have developed a novel method to study molecule reactions by isolating two molecules on a substrate and controlling their reaction with ultraviolet light. This breakthrough in organic chemistry has potential applications in improving the efficiency of solar cells.
A UCLA research team has developed a device using Velcro-like nanoscale technology to efficiently identify and capture circulating tumor cells, or CTCs, in blood samples. The new approach captures a greater number of CTCs than existing methods and could enable early detection and diagnosis of cancer.
Researchers at UCLA have successfully demonstrated the feasibility of using proteins as a significant raw material for biorefining and biofuel production. This breakthrough could potentially reduce greenhouse gas emissions by recycling nitrogen from protein biomass.
UCLA researchers found a correlation between nicotine addiction and decreased prefrontal cortex activity in adolescent smokers. The study suggests that smoking can affect brain function, particularly during adolescence when the prefrontal cortex is still developing.
A UCLA study found that body language is more likely to be judged as masculine when it conveys anger and as feminine when it conveys sadness during baseball tosses. Researchers used technology to disguise the actors' sex and presented videos to observers, who made judgments about their emotions and gender.
Biologists found that larger social groups lead to more unique voices and easier identification of individuals; this helps explain our own uniqueness as humans and other social creatures,
Researchers have discovered a thick stellar disc in the Andromeda galaxy, composed of older stars with distinct chemical and orbital properties. This finding sheds light on the formation and evolution of spiral galaxies like our own Milky Way.
Researchers at UCLA develop topological insulator nanoribbons to enable high-performance, low-dissipation electronic devices. The team successfully controls surface conduction and demonstrates significant progress toward practical device applications.
The UCLA Neurology program played a key role in assessing stroke rehabilitation, finding that patients who received physical therapy at home improved their walking ability comparable to those treated in a clinic. Early locomotor training did not seem to matter, with all groups showing similar gains in walking speed and mobility.
A comprehensive review of 27 long-term studies found that children with ADHD are two to three times more likely to develop serious substance abuse problems in adolescence and adulthood. The research, published in Clinical Psychology Review, analyzed data from approximately 4,100 children with ADHD and 6,800 without the disorder.
A study published in Biology Letters reveals a strong correlation between habitat change and significant adjustments in body size among turtles and tortoises. The research shows that chelonians living in marine or island habitats have an optimal body size several times larger than their cousins on the mainland.
A team of UCLA researchers has developed a chemically defined culture medium that supports the long-term quality and maintenance of human embryonic stem cells. The new medium, using a feedback system control scheme, eliminates the need for animal products and enables routine single-cell passaging.
Research at UCLA reveals that coffee's protective effect against type 2 diabetes may be linked to increased SHBG levels. Women who drink four cups of coffee daily are less than half as likely to develop diabetes compared to non-coffee drinkers.
The discovery of an ancient wine production facility in Armenia has confirmed that humans were producing wine 6,100 years ago. The facility, dated between 4100 B.C. and 4000 B.C., included a wine press, fermentation vats, and storage jars, providing the oldest complete archaeological picture of wine production.
Researchers developed a non-invasive ultra-high-speed microscope to visualize brain activity in real-time, recording the firing of thousands of individual neurons in 3D. This technology could help decipher 'miscommunications' in neuropsychiatric disorders like autism and schizophrenia.
Researchers at UCLA have made a groundbreaking discovery about neuronal gap junctions, which could lead to new treatments for anxiety disorders like PTSD. The study found that blocking these gap junctions can disrupt critical rhythms in the brain region most involved in cognition, preventing fear memories from forming.
A UCLA study found that college graduates from underprivileged backgrounds are up to 10 times more likely to volunteer than their non-college-educated counterparts. In contrast, advantaged graduates show a five-fold increase in volunteering rates compared to non-college graduates.
Researchers at UCLA discovered that randomly dispersed microparticles can self-assemble into a highly organized structure as they flow through microscale channels. This phenomenon is driven by hydrodynamic interactions between particles, fluid, and the conduit they flow through.
A study by UCLA researchers found that Medicaid-funded ADHD treatment for children yielded poor quality care, with few follow-up visits and inadequate medication use. The study suggests areas for improvement in ADHD care, including better alignment of clinical severity with provider type and increased use of stimulant medication.
Researchers at UCLA are developing spin-transfer torque magnetoresistive random access memory (STT-RAM) with great potential over current memory technologies. The technology has achieved densities comparable to dynamic random access memory and speeds comparable to static random access memory.
The newly discovered fourth planet (HR 8799e) orbits a bright star called HR 8799, which lies some 129 light years from Earth and is faintly visible to the naked eye. The mass of the HR 8799 planetary system is much greater than our own.
A new UCLA study warns that mandatory genetic screening of newborns for rare diseases is creating unexpected upheaval for families whose infants test positive but show no immediate signs of the diseases. The study found that parents are often left in limbo, waiting months for conclusive evidence and facing trauma as a result.
Researchers found that marmots' social behavior has a genetic component, with aggression tolerance and friendly interactions heritable traits. The study, led by UCLA biologists, used social network statistics to analyze the behavior of yellow-bellied marmots over six years.
UCLA is leading a $8.4 million DARPA-funded project to develop ultra-low power, non-volatile logic technologies. The research will explore materials, design, fabrication and tools for such technologies with broad implications across various fields including electronics, sensors and computing.
Researchers at UCLA have discovered a way to strengthen polyunsaturated fatty acids, making them less susceptible to oxidation. This breakthrough could lead to the development of more effective nutritional supplements and new approaches to combatting neurodegenerative diseases like Parkinson's and Alzheimer's.
Researchers found that women call their fathers less frequently and hang up sooner during high-fertility days, possibly to avoid male control. They also spent more time on phone calls with mothers, suggesting an unconscious drive for reproductive success.
A new tool has been developed to measure the quality of patient care for people with brain disorders, including Parkinson's disease. The tool evaluates non-motor symptoms, diagnosis and treatment, safety, and more, providing a comprehensive assessment of care.
Biologists report that polar bears are unsuited for alternative diets in a warmer world, where they will come into competition with grizzly bears. The study suggests that polar bears' weaker skulls make them less competitive for resources.
A team of researchers developed a dual scanning tunneling and microwave-frequency probe to study nanoscale interactions, enabling the measurement of physical, chemical, and electronic interactions between single molecules and substrates. The probe can locate and switch single molecule switches on substrates with high resolution.
Researchers at UCLA have identified a molecular program that drives brain cell connections after stroke, activating genes to form new connections. The program differs between young and aged adults, with older brains slowing down recovery through simultaneous activation of repair and collapse genes.
Researchers at UCLA have created a three-dimensional structural model of the RNA core domain of the telomerase enzyme, which plays a critical role in cancer cell immortality. The new model provides insights into how telomerase functions and could lead to new approaches for treating diseases associated with telomerase activity.
A team of UCLA chemists and engineers has developed a new method for coating large surfaces with nanofiber thin films that are both transparent and electrically conductive. The technique, published in the Proceedings of National Academy of Sciences, uses a solution-based approach and can be applied to virtually any surface.
A new microfluidics-imaging platform can detect cancer growth signaling in tiny biopsy samples, allowing for faster and more efficient screening. This method uses an integrated platform to measure kinase activity from as few as 3,000 cells, enabling direct experimentation on patient samples.
A new UCLA–Harvard University study found that birds of a feather don't always flock together; instead, plain social pressure and shared characteristics like ethnicity, major, or state of origin play stronger roles in forming friendships. Social pressure proved seven times stronger than shared racial background.
Researchers demonstrate that individuals can intentionally alter the firing rate of specific neurons in the brain, increasing some while decreasing others. This control is achieved through focusing thoughts on particular images displayed on a computer screen.
Researchers detected large areas of water ice in the lunar south pole using NASA's Diviner instrument. This discovery suggests that these regions are suitable for future human missions, as subsurface water ice is more stable and protected from radiation.
New research from UCLA and the British Antarctic Survey reveals that chorus waves are responsible for scattering trapped electrons into the Earth's atmosphere. The findings have significant implications for understanding space weather and its effects on satellites, power grids, and aviation industries.
Research consensus establishes DBS as a treatment option for patients with severe Parkinson's symptoms, including tremors and motor fluctuations. The study provides guidelines for patient selection and surgical approach, emphasizing the importance of experienced teams and neurosurgeons.
A UCLA-led research team found that bacteria can stand upright and 'walk' during biofilm formation, allowing them to explore surfaces more effectively. This unique behavior is enabled by type IV pili appendages and plays a critical role in bacterial detachment from surfaces.
UCLA Engineering has received a $6 million award from NIST to construct the Western Institute of Nanotechnology on Green Engineering and Metrology (WIN-GEM), a cutting-edge facility supporting energy conservation technologies in microelectronics and nanotechnology.