Researchers create high-throughput flow-through optical microscope to classify rare breast cancer cells in blood samples, boasting a throughput of 100,000 cells per second. The technology demonstrates real-time identification of rare cancer cells with a record low false-positive rate.
Astronomers have discovered an extraordinary amount of dust around a nearby star that has mysteriously disappeared. The dusty disc was bigger and more massive than Saturn's rings and would have extended from the sun halfway out to Earth if it were in our solar system.
The UCLA School of Dentistry has received a $5 million NIH grant to create a comprehensive research training program for dentist-scientists and oral health researchers. The program aims to cultivate the next generation of leaders in science and research.
Researchers at UCLA have identified a new compound, RTC13, that effectively counteracts 'nonsense' mutations causing Duchenne muscular dystrophy. The compound was found to partially restore full-length dystrophin protein, improving muscle strength in mice.
Researchers at UCLA found that glucose starvation activates a metabolic and signaling amplification loop that leads to cancer cell death. The discovery reveals the power of systems biology in uncovering relationships between metabolism and signaling.
A UCLA research team created the world's most powerful nanoscale microwave oscillators, which could lead to cheaper and more energy-efficient mobile communication devices. The new oscillators use electron spin instead of charge, offering significant advantages over current silicon-based oscillators.
A new study uses Lotka–Volterra equations to map street gangs' territories, finding that most crimes occur near the borders between rival gangs. The research provides insights into how law enforcement can allocate resources more effectively.
A classic study on male and female promiscuity has been called into question after UCLA biologists repeated the experiment using the same methods as the original. The team found that Bateman's conclusions about the relationship between mate number and offspring fitness were likely flawed due to a bias in his methodology.
Researchers have discovered how a key protein assembles telomerase, an enzyme crucial for preventing DNA degradation and cancer cell proliferation. The study sheds new light on the telomerase enzyme's structure and function, which may help predict its behavior in humans and other organisms.
Scientists have found that woolly mammoths' extinction was caused by a combination of climate warming and habitat change, with human-induced climate change mirroring the same pressures. The researchers used radiocarbon dating to create detailed maps of changes in plant species, forest development, and human settlements over time.
A UCLA program has proven effective in teaching social skills to high-functioning autistic teens, leading to improved relationships and social functioning. The PEERS clinic's 14-week program helps teens develop critical skills needed to make and keep friends, resulting in fewer problem behaviors and greater understanding of social skills.
Distorted music triggers strong emotional responses by tapping into distress calls of animals, according to UCLA researchers. Listeners rate music with distortion as more exciting and charged with negative emotion than neutral compositions.
A research team led by UCLA professor John Wallace is receiving a $1 million grant to examine the construction issues with modern buildings' structural walls after recent earthquakes in Japan, New Zealand, and Chile. The team will investigate design and performance limits for structural walls to improve building codes and resilience.
Researchers have designed specialized proteins that assemble to form tiny molecular cages, which may be used for drug delivery or as artificial vaccines. The cages are hundreds of times smaller than a single cell and can be decorated with virus-identifying proteins to stimulate an immune response.
Researchers at UCLA have identified the genetic mutation responsible for IMAGe syndrome, a rare disorder that stunts infants' growth. The discovery could lead to new ways of blocking rapid cell division and offers a new tool for diagnosing children with IMAGe syndrome.
A team of researchers has developed a new genetic method called spatial ancestry analysis (SPA) that can model genetic variation in two- or three-dimensional space. SPA allows for the modeling of the spatial distribution of each genetic variant, enabling individuals to be localized on a world map based on their genetic information alone.
Researchers discovered predictable relationships in leaf vein systems that can predict past climates using the fossil record. The study found larger leaves have major veins spaced further apart, regardless of other variations.
UCLA researchers have developed a method to stabilize proteins using polymers, which could lead to improved protein-based therapeutics. The study found that attaching the polymer to the protein resulted in better stability during lyophilization and heat treatment.
A large survey of human genetic variation reveals that rare genetic variants are surprisingly common, affecting millions of people. The study, published in Science, found that one individual in 14,002 had a unique variant in each of 202 genes.
Researchers at UCLA have mapped the damaged connections in Phineas Gage's brain, revealing widespread damage to white matter pathways. The study, published in PLoS ONE, suggests that the disruption of these connections had a significant impact on Gage's personality and behavior.
Vesta's surface boasts a diverse array of terrain, including large impact craters and steep slopes. The planet's composition suggests it once had a molten interior, with an iron core at its center.
Researchers used lithography to create achiral particles that spontaneously formed chiral super-structures with distinct orientations. Entropy played a key role in the emergence of chirality, contradicting traditional views on disorder and order. The discovery sheds new light on the physical origins of molecular handedness.
Researchers from UCLA created a crowd-sourced online gaming system where players distinguish malaria-infected red blood cells from healthy ones, achieving accuracy within 1.25% of medical professionals. The platform has potential to overcome limitations in malaria diagnosis, affecting 210 million people annually.
Researchers at UCLA have developed a novel screening technology to rapidly test metal-oxide nanomaterials for potential health hazards. The method uses high-throughput screening and predicts which materials are most likely to cause oxidative damage based on their electronic properties.
Researchers have created a new instrument that rapidly analyzes the physical properties of cells to identify cancer and other cell states. The deformability cytometer measures cells' responses to fluid flow, providing valuable information about cell health.
UCLA researchers have developed a compact and cost-effective RDT-reading device that works in tandem with standard cell phones. The platform can read nearly every type of RDT, eliminating manual decision-making errors. It wirelessly transmits results to a global server, creating maps charting disease spread worldwide.
A study using brain data predicts which ads will be most effective, contradicting participants' own predictions. The medial prefrontal cortex region was found to predict successful ads, with campaign 'C' boosting phone calls thirty-fold.
Researchers found that people consistently judge pistol-packers to be taller and stronger than men holding other objects, even when hand size and appearance are similar. The study suggests an unconscious mental mechanism that gauges threat and translates it into size and strength dimensions.
A UCLA study resolves decades-old debates on plant drought tolerance, finding that saltier cell sap is key to survival. The team's discovery allows for predictions of which species can thrive in dry environments.
A new study by UCLA researchers has discovered a single instance of two independent mutations disrupting the SCN2A gene in affected siblings, confirming its importance. The study found multiple variations between unaffected and affected groups, making promising new candidates for autism susceptibility genes.
Researchers at UCLA have developed a method to store electrical energy as chemical energy in higher alcohols, which can be used as liquid transportation fuels. They genetically engineered a microorganism to produce isobutanol and 3-methyl-1-butanol using carbon dioxide and electricity.
A new study by UCLA researchers found that the brain responds differently to antidepressant medication based on prior treatment history. Subjects who had never taken an antidepressant showed large increases in prefrontal brain activity during placebo treatment, while those with prior experience exhibited slight decreases in activity.
Researchers at UCLA have developed a new method for directly measuring the atomic structure of nanomaterials, enabling 3D imaging of individual atoms. The technique, known as electron tomography, allows scientists to visualize the interior structure of nanoparticles in unprecedented detail.
Researchers at UCLA have developed graphene-based electrochemical capacitors that store substantial amounts of charge, far surpassing traditional batteries. These devices exhibit ultrahigh energy density values while maintaining high power density and excellent cycle stability.
Long-term meditators have larger amounts of cortical gyrification, indicating improved neural processing and information processing. The study also found a positive correlation between meditation years and insular gyrification, supporting the idea that meditation enhances regional brain structure.
A new study found that a brief, daily yoga meditation program reduced depressive symptoms and improved mental health in caregivers. The program also showed increased telomerase activity, slowing cellular aging.
A new study by UCLA scientists has discovered that over 2,000 genes in the brain of zebra finches are significantly linked to singing. These genes, which include FoxP2 and reelin, may also play a critical role in human speech and speech disorders such as stuttering and autism.
Researchers found that early surgical intervention followed by antiepileptic drugs stopped seizures and improved quality of life for patients with medically intractable temporal lobe epilepsy. The study suggests that surgery should not be viewed as a last resort for these patients.
Researchers at UCLA have discovered a novel compound called CLR01 that prevents α-synuclein protein aggregates from forming, stopping their toxicity and even breaking up existing aggregates in the brain. This breakthrough holds promise for slowing or stopping Parkinson's disease progression and may lead to human clinical trials.
Researchers at UCLA find hyperconnectivity in depressed brains, suggesting a malfunction in regulating brain networks. This dysregulation may explain multiple symptoms of depression, including anxiety and memory issues.
A combination of guideline-recommended therapies for heart failure treatment significantly improved two-year survival rates. Adding each therapy incrementally increased the overall survival rate, with a maximum 83% reduction in mortality at four-to-five-therapy plateau.
Researchers found that traumatic brain injuries increased susceptibility to PTSD and anxiety disorders in rats, highlighting the need for precautions against stressful situations. The study suggests a mechanistic link between TBI and PTSD, with the amygdala playing a critical role.
Researchers at UCLA have developed a new tandem polymer solar cell structure, which achieves an unprecedented power-conversion efficiency of 10.6%, surpassing previous records. The device combines multiple cells with different absorption bands to effectively harvest a broader spectrum of solar radiation.
A team led by UCLA researcher Michael Rich has discovered a previously unknown dwarf galaxy near NGC 4449, which is 12.5 million light years from Earth. The newly found galaxy, NGC 4449B, is the largest known dwarf galaxy in the local group and has been stretched into a 'S' shape due to gravitational encounter.
A recent study by UCLA psychologists analyzed 172 married couples over 11 years, finding that a deeper level of commitment is a better predictor of lower divorce rates and fewer problems in marriage. Couples who were willing to make sacrifices within their relationships were more effective in solving their problems.
Researchers used data from orbiting spacecraft to discover that energetic electrons are swept away by solar wind particles during periods of heightened solar activity. The findings aim to improve predictions of geomagnetic storms and protect satellites and astronauts.
Researchers found that minuscule amounts of ethanol double the life span of a tiny worm, while higher concentrations are harmful. The discovery raises intriguing possibilities for human health benefits, but more research is needed to understand the mechanism behind this effect.
Researchers found that low iron levels in adolescence can affect the brain's physical structure, leading to changes in brain regions vulnerable to neurodegeneration. High iron levels during adolescence may also impact brain wiring and myelin production, potentially increasing the risk of diseases like Alzheimer's and Parkinson's.
A study at UCLA has identified 56 proteins that show significant differences between people with familial Alzheimer's disease and those without it. The changes may represent an early manifestation of the loss of critical brain structures, providing potential new targets for drug interventions.
Researchers at UCLA's Laboratory of Integrative Neuroimaging Technology use functional MRI brain scans to study mental activity patterns. They employ computerized machine learning methods to identify cognitive states and anticipate neurocognitive changes similar to predictive text-entry for cell phones and Internet search engines.