UCLA researchers found that smokers who ingested high levels of flavonoids had a lower risk of developing lung cancer. Flavonoids are water-soluble plant pigments with antioxidant and anti-inflammatory properties.
Researchers at UCLA identified a type of leukemia stem cell and uncovered the genetic mechanisms that cause normal blood stem cells to become cancerous. This discovery may lead to new therapies targeting these stem cells, potentially curing certain cancers.
Researchers found a 27% reduced incidence of prostate cancer in mice on a low-fat diet compared to those on a Western-style diet. The study suggests that lowering dietary fat intake may slow the growth of precancerous cells and prevent prostate cancer development.
A study led by UCLA researcher Istvan Molnar-Szakacs aims to understand how children with ASD process emotions through musical excerpts and facial expressions. The goal is to develop more optimal interventions and promote music as a powerful tool for brain function research.
Tropical species will experience reduced health and population growth rates due to global warming, while high-latitude species may benefit slightly from warmer temperatures. The impacts of global warming on species in the tropics will be more detrimental than those in high latitudes.
Researchers found that low-dose amitriptyline significantly improves overall quality of life for adolescents with irritable bowel syndrome. The study, published in the Journal of Pediatrics, shows that patients receiving antidepressant therapy experience reduced symptoms and improved quality of life.
Scientists at UCLA have successfully differentiated induced pluripotent stem cells (iPS cells) into three types of cardiovascular cells, including cardiomyocytes, endothelial cells, and vascular smooth muscle cells. This discovery could potentially lead to new therapies for heart attacks, atherosclerosis, and other cardiovascular disea...
A new UCLA study identified common precipitating factors that may contribute to hospital admissions nationwide for heart failure. Researchers found pneumonia, irregular heart beats, and obstructed blood flow to the heart as the most frequent contributing factors.
Researchers at UCLA have discovered a theoretical model that can accurately predict the behavior of dense granular flows, similar to molecules in jammed materials. This breakthrough has significant implications for fields such as materials innovation, medicine, and geology, offering new avenues for understanding complex phenomena.
UCLA researchers found that people tend to accept fair offers over unfair ones, with the brain responding similarly to winning money or eating chocolate. The study suggests that humans have an innate preference for fairness, which can be regulated through self-control.
Researchers have created a novel nanomachine, called nanoimpeller, that can capture and store anticancer drugs inside tiny pores and release them into cancer cells in response to light. The device has strong implications for cancer treatment and may open a new avenue for drug delivery under external control.
A study by UCLA researchers found significant disparities in healthcare quality for African Americans, Hispanics, and non-Hispanic whites in California's Medi-Cal program. The study suggests that efforts to improve services for minority populations could lead to better health outcomes and reduced healthcare costs.
Researchers from UCLA used high-resolution technique array CGH to examine the genome of two human embryonic stem cell lines, finding differences in gene numbers that could impact disease susceptibility and therapeutic applications. These differences can provide a unique genetic fingerprint for each line, enabling researchers to choose ...
The research successfully created designer enzymes for a chemical reaction known as the Kemp elimination, a non-natural chemical transformation in which hydrogen is pulled off a carbon atom. The researchers also designed an active site for the aldol reaction, involving at least six chemical transformations.
A new feedback control scheme can search for the most effective drug combinations to treat various conditions, including cancers and infections. The discovery holds promise for facilitating new clinical drug-cocktail trials and optimizing combination therapies while reducing side effects.
A UCLA study found that broccoli's sulforaphane can switch on antioxidant genes and enzymes in immune cells, combating oxidative tissue damage. This could lead to a decline in age-related decline in immune function.
Researchers at UCLA have solved a 40-year-old puzzle by identifying the source of intense radio waves in the Earth's upper atmosphere that control the dynamics of the Van Allen radiation belts. The chorus wave type is found to energize electrons and was initially thought unrelated to hiss.
Researchers have made a groundbreaking discovery about the origin of blood stem cells, finding that they are generated in the placenta. The study's findings may allow for the growth of blood stem cells in cell culture, potentially leading to new treatments for diseases like leukemia and aplastic anemia. By understanding how blood stem ...
The UCLA Department of Family Medicine has launched a network to study health care disparities affecting minorities, particularly those with chronic diseases. The Network for Multicultural Research on Health and Healthcare will mentor researchers and address quality of care for underserved populations.
Researchers at UCLA have solved a decades-old mystery in hydrogen gas storage, enabling the creation of more efficient and environmentally friendly vehicles. The study found that adding titanium to sodium alanate can store high-density hydrogen at reasonable pressures and temperatures.
A new UCLA report calculates that the federal poverty line grossly underestimates the basic costs of living for California's seniors, with average annual costs ranging from $21,011 to $37,263. The Elder Index provides a more comprehensive look at expenses elders face.
Researchers have identified the proteins forming the structure of carboxysome microcompartments, a key step in understanding their role in bacterial protection. The discovery may lead to new strategies for targeting these structures, potentially rendering bacteria harmless.
Researchers at UCLA's Jonsson Cancer Center found that hormone refractory prostate cancers are more invasive and likely to spread to other organs than androgen-dependent cancers. The study suggests that blocking overexpression of the androgen receptor could prevent cancer spread.
A novel mathematical model predicts a rise in drug-resistant HIV infections among men in San Francisco, but surprisingly reduces the epidemic's severity. The Amplification Cascade Model suggests that resistance to certain classes of drugs will decline, while others will rise, leading to less infectious strains.
Researchers at UCLA discovered that fruit flies integrate visual and olfactory information to track odors, using visual markers to navigate through complex environments. This crossmodal integration enables flies to efficiently find food despite their limited sensory capabilities.
UCLA chemists have developed a new class of materials called zeolitic imidazolate frameworks (ZIFs) that can selectively capture carbon dioxide, storing it like a reservoir. ZIFs outperform current porous carbon materials, capturing five times more carbon dioxide and requiring less energy.
UCLA stem cell scientists have successfully reprogrammed human skin cells into embryonic stem cells without using embryos or eggs. This breakthrough uses genetic alteration to turn back the clock on human skin cells and create cells nearly identical to human embryonic stem cells, which can become every cell type in the human body.
Researchers found that men with physically active jobs had a lower risk of developing prostate cancer compared to those with low-activity jobs. The study also revealed that increased physical activity was associated with reduced exposure to carcinogenic chemicals.
A new UCLA Medical Center study shows that select patients age 65 and older can safely undergo lung transplantation with acceptable outcomes. The study found similar survival rates between younger and older patients, suggesting that age should not preclude patients from the procedure.
Women with irritable bowel syndrome (IBS) who experienced sexual and/or physical abuse may have a heightened brain response to pain, making them more sensitive to abdominal discomfort. Researchers found that patients with IBS background of abuse were less effective in turning off a pain modulation mechanism in the brain.
A UCLA study found PET scanning more sensitive and accurate than conventional imaging methods in detecting treatment response in sarcoma patients. Standard size-based evaluation methods only identified 20% of responders, while PET accurately picked up all responders.
Researchers at UCLA's Jonsson Cancer Center have discovered biomarkers that can help personalize treatment for patients with advanced non-small cell lung cancer. These biomarkers may identify patients who will respond to the Celebrex and Tarceva combination therapy, sparing them from ineffective treatments.
Researchers create a localized and controlled drug delivery system that is invisible to the immune system, providing a potential solution for cancer and other diseases. The system uses nanoscale polymer films to slowly release anti-inflammatory drugs, reducing side effects and enhancing treatment efficacy.
A new UCLA study found that only half of children diagnosed with ADHD exhibit cognitive defects, challenging the common method for diagnosing the disorder. The research also suggested that medication is not always effective in treating ADHD, highlighting the need for alternative approaches to address long-term problems.
Researchers at UCLA have identified a key protein in dendritic cells that can stop HIV from 'budding', a crucial step in its life cycle. DC-SIGN and DC-SIGNR demonstrated strong inhibition of viral production, rendering released particles uninfectious.
Researchers at UCLA discovered a strong association between the contactin-associated protein-like 2 (CNTNAP2) gene and autism, particularly in boys. The study found that CNTNAP2 is most active in brain regions involved with language and thought, suggesting a link to speech delay and other symptoms of autism.
Researchers found that human auditory neurons can detect subtle frequency differences down to a tenth of an octave, surpassing other mammals. This sensitivity may be linked to musical skill and cognitive abilities such as working memory.
Researchers found that women with IBS cannot turn off a pain modulation mechanism in the brain, making them more sensitive to mild discomfort. The study suggests that abnormal brain responses may be the root cause of the disorder and could lead to new treatment approaches.
Researchers discovered that the central nervous system can reorganize itself and follow new pathways to restore cellular communication required for movement. The study, published in Nature Medicine, shows that most mice regained mobility within eight weeks after spinal cord damage was induced.
A new UCLA AIDS Institute study found that newly homeless youth are more likely to engage in risky sexual behavior if they lack supervision and social support. Drug use also plays a significant role in this behavior, particularly among females living in nonfamily settings.
Researchers found that omega-3 fatty acid DHA increases LR11 production, protecting against Alzheimer's disease. Low levels of LR11 lead to toxic plaques associated with the disease.
Researchers at UCLA have successfully captured and measured the statistical properties of optical rogue waves, which are brief pulses of intense light. The study's findings may help develop mathematical models that can identify conditions leading to rare but extreme events in various fields.
The study uses fMRI to show that different regions of the brain are activated when people believe, disbelieve or are uncertain about statements. The ventromedial prefrontal cortex is involved in belief processing, while the limbic system's cingulate areas are engaged in disbelief.
A UCLA study found that introducing a lunch salad bar in elementary schools significantly increased low-income students' daily fruit and vegetable intake, with a notable decline in unhealthy fats. The program's success highlights the importance of accessible healthy food options in promoting healthier eating habits among children.
People with BDD perceive themselves as ugly and disfigured, despite normal brains. Functional imaging reveals abnormal brain processing of visual details, with the left side activated more often than in controls.
Researchers at UCLA used Atomic Force Microscopy to measure the softness of living cancer cells from patient samples, distinguishing them from normal cells. This method may aid in diagnosing cancer and personalizing treatments.
A new study is expanding to include patients with severe strokes who cannot give informed consent, aiming to determine if early administration of magnesium sulfate improves patient outcomes. The trial has already enrolled over 250 patients and aims to answer a crucial question about the best approach to stroke treatment.
A team of researchers at UCLA has modeled the structure of the largest cellular particle ever crystallized, proposing ways to engineer vaults for targeted drug delivery. The proposed atomic structure consists of a barrel-shaped shell with 96 identical protein chains, offering a human-friendly nanocontainer for therapeutic applications.
Researchers tested a pilot program to change older adults' beliefs about aging, resulting in increased physical activity and improved mental health-related quality of life. The program, which combined attribution retraining with weekly exercise classes, showed significant increases in walking levels and age-expectation survey scores.
A team of scientists has identified astrophysical objects with charged particles reaching Earth at high energies. The Pierre Auger Observatory in Argentina recorded the particles, which carry as much energy as a bullet or a tennis ball off Roger Federer's racket.