A UCLA study found that most cancer patients with ocular melanoma would want genetic testing to predict metastasis risk, regardless of treatment availability. The test results showed little impact on quality of life or depression symptoms, suggesting it could provide a valuable tool for planning and emotional preparation.
Researchers found that local intestinal inflammation induced DNA damage to lymphocytes in peripheral blood, indicating systemic genetic damage. Chromosome damage was detected in the blood before colitis onset and correlated with disease severity.
According to a new study, nearly 952,000 California adults seek medical, dental, or prescription services in Mexico each year. The primary reasons for this trend include cost and lack of insurance.
A recent study published in Annals of Internal Medicine found that elderly women with hyperkyphosis, or 'dowager's hump,' are at a higher risk for premature death. The study, which analyzed data from over 610 women, suggests that the increased spinal curvature itself may be predictive of adverse health outcomes.
Researchers at UCLA have discovered a link between a variant of the CACNA1G gene and increased autism risk in boys. The study found that nearly 40% of the population carry the common variant, which increases the correlation to autism spectrum disorder.
Researchers have identified a potential new focus for treating osteoporosis and periodontitis by inhibiting nuclear factor-kB, a master protein controlling inflammation and immunity. This balance is crucial in bone formation and resorption.
A new UCLA study reveals that traumatic brain injuries in children can lead to persistent cognitive problems, emphasizing the need for targeted treatment and prevention through helmet use and seatbelt safety. The research also found that younger children are disproportionately affected by severe TBI.
A UCLA study found that meditation increases gray matter in areas of the brain regulating emotions, leading to improved emotional stability and mindful behavior. Long-term meditators showed significantly larger volumes in regions such as the hippocampus and orbito-frontal cortex.
A new theory of social change and development by UCLA professor Patricia Greenfield explains how values and behaviors are shaped by societies. The world is moving towards a Gesellschaft direction, with immigrants adapting to urbanized, high-tech environments, leading to conflicts between traditional and modern values.
Researchers found a new frog species, Huia cavitympanum, with eardrums recessed in the skull, allowing it to detect and produce high-frequency ultrasounds. The frogs use both audible and ultrasonic calls for communication, which may have implications for improving human hearing aids.
Researchers found that interleukin-21 (IL-21) sustains T-cells' ability to mount an immune response during long-lasting infection. Without IL-21, CD8 T-cells dwindle, preventing the immune system from containing viral spread.
Researchers have found a connection between Sanfilippo syndrome and Alzheimer's disease, suggesting that new Alzheimer's drugs may provide therapy for the currently untreatable metabolic disorder. The study identified key proteins involved in the development of the disease, which could lead to effective treatment options.
Physicists at UCLA have created the world's smallest incandescent lamp, utilizing a single carbon nanotube filament that is only 100 atoms wide. The tiny lamp can study black-body radiation and its structure was imaged using an electron microscope with atomic resolution.
A study published in Menopause found a significant link between hot flashes and lower bone mineral density in women. Postmenopausal and premenopausal women with vasomotor symptoms exhibited lower lumbar and total hip bone mineral density compared to those without VMS.
A UCLA archaeologist finds that eBay's online auction house has an unexpected chilling effect on looting of antiquities, diverting villages to producing fake artifacts instead. The proliferation of these copies reduces incentives to loot and depresses the market for real items.
A new study suggests that the widely used diabetes medication Januvia may cause pancreatitis and increase the risk of pancreatic cancer in some patients. Researchers found that combining Januvia with the older diabetes drug metformin helped mitigate these effects, suggesting a potential way to safely use GLP-1 class drugs.
Researchers at UCLA developed a novel camera that captures images at 6 million frames per second, overcoming conventional camera limitations. The camera's optical image amplification enables continuous real-time imaging of rapid phenomena in physics, chemistry, and biology.
Researchers have identified a new gene variant associated with autism, found to be highly active in fetal brain regions critical for language and social behavior. The study suggests that this gene variant may contribute to an increased prenatal risk of autism.
A new study published in American Journal of Public Health found that 15% of fifth-grade students reported experiencing racial or ethnic discrimination, which may lead to symptoms of depression, ADHD, and other mental health disorders. The study highlights the need for parents, clinicians, and teachers to address this issue and provide...
Researchers found a 75% increased risk of Parkinson's disease among Central Valley residents exposed to maneb and paraquat between 1974 and 1999. Earlier exposure, particularly in childhood or adolescence, significantly increased the risk, especially for those diagnosed at age 60 or younger.
Researchers found that countries with high levels of ethnic exclusion are more likely to experience civil war. The study, led by UCLA professors Andreas Wimmer and Lars-Erik Cederman, analyzed data on ethnic power relations in 155 countries from 1946 to 2005.
The UCLA center aims to prevent second strokes in survivors by exploring innovative models of care and neighborhood interventions that reduce risk factors. Researchers will collaborate with community partners on studies to develop effective preventive treatments.
Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed a non-invasive method to determine whether chemotherapy is working after a single treatment cycle, allowing oncologists to discontinue ineffective treatments sooner. This breakthrough enables faster decision-making and potentially improves patient outcomes.
A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs. Researchers have developed a novel compound, MDV3100, which blocks the androgen receptor in CRPC cells, lowering PSA levels and reducing tumor growth.
A special class at UCLA helps high-functioning teens with autism spectrum disorders learn social etiquette and interact with peers. The program, PEERS, focuses on teaching rules of social behavior and provides parents with guidance to support their child's development.
Researchers at UCLA have identified a gene mutation responsible for short-rib polydactyly syndrome, a deadly disorder that kills newborn babies. The discovery will allow for earlier testing of embryos at risk for the disease, potentially saving lives and reducing the emotional burden on families.
African Americans are disproportionately affected by AIDS, yet few are pursuing HIV/AIDS research due to historical, social, and other factors. Recommendations from UCLA researchers aim to reverse the trend by supporting partnerships, retraining, mentorship, and culturally congruent research.
The study discovered a mechanism that switches on genetic instability in cancer cells, leading to growth advantage and invasion. The researchers developed an assay to determine the efficiency of DNA repair mechanisms, which could lead to developing ways to switch off this mechanism.
A new UCLA study analyzes data from the Surveillance and Epidemiology End Result (SEER) cancer registry and the National Health Interview Survey (NHIS), finding that African Americans are more likely to get cancer in the first place, contributing to a life expectancy disparity of 1.47 years for men and 0.91 years for women.
A study by UCLA researchers found that teenage stress is associated with higher levels of inflammation, a potential indicator for cardiovascular disease. Daily interpersonal stress experienced during high school years was linked to elevated CRP levels even among healthy teens.
A study by UCLA researchers found that teenage stress is associated with higher levels of inflammation, which can lead to cardiovascular disease. Daily interpersonal stress experienced during high school years was linked to elevated CRP levels in healthy teens.
A UCLA study found that broccoli sprouts triggered an increase in antioxidant enzymes, offering protection against free radical damage and inflammation. The researchers discovered a significant increase in these enzymes after consuming 100g or higher of broccoli sprouts.
Scientists at UCLA have successfully differentiated human induced pluripotent stem (iPS) cells into electrically active motor neurons, similar in function and efficiency to those derived from human embryonic stem cells. This discovery may open the door for new treatments for neurological disorders using patient-specific cells.
A new UCLA study found that drinking at least three cups of green or black tea a day can significantly reduce the risk of stroke. The study suggests that the antioxidant compounds in tea, such as EGCG and theanine, may be responsible for this effect.
A new study found that gene therapy can be developed as a potentially effective treatment for HIV, reducing viral load and preserving the immune system. The technique involves delivering genes to cells to prevent viral replication, with promising results in a clinical trial involving 74 HIV-positive adults.
According to UCLA behavioral ecologist Daniel T. Blumstein, biology and evolution offer valuable lessons on managing security threats. By studying species' risk management strategies, we can learn how to allocate energy to defense versus other things, and how not to overreact.
Researchers found that a novel mutated variant of a gene in dogs is responsible for the black coat color in wolves, transferred through matings. The discovery suggests that natural selection has increased the frequency of black coat color in wolf populations across North America.
UCLA researchers have created a non-invasive probe that enables real-time monitoring of chemotherapy drug activity in living bodies. This allows doctors to quickly pinpoint the most effective treatment and personalize it to each patient's unique biochemistry, reducing wasted time and toxic side effects.
Researchers at UCLA School of Public Health have found evidence that perfluorinated chemicals (PFCs), used in household items and manufacturing processes, may be linked to infertility in women. Women with higher levels of PFOS and PFOA in their blood took longer to become pregnant.
The Burroughs Wellcome Fund Inter-school Training Program in Metabolic Disease (BWF-ITP-MD) combines multiple disciplines to understand metabolic diseases, from molecular mechanisms to population health. The program aims to develop comprehensive insights and system strategies to curb the epidemics of obesity and diabetes.
A study found that hospitals in states where Medicaid does not cover routine male circumcision are half as likely to perform the procedure, leading to increased risk of HIV infection among lower-income children. The study also highlights disparities in healthcare services for Hispanic communities.
Research suggests that excessive technology use may lead to a decline in critical thinking and analysis skills, while visual skills improve. Experts recommend a balanced media diet and encouraging reading for pleasure to develop essential skills.
Scientists have successfully reprogrammed human induced pluripotent stem (iPS) cells into the cells that eventually become eggs and sperm. This breakthrough may lead to new treatments for infertility using patient-specific cells. However, further research is needed to determine if iPS-derived germ cells can correctly regulate themselves.
A new study found that marginalized groups fare worse in the aftermath of natural disasters and experience greater terrorism-related fears. Researchers discovered that these groups tend to overestimate the threat of terrorism and make more behavioral changes based on those fears.
Researchers built a novel device to study convection in rotational systems, providing new insights into how it controls planetary and stellar behavior. The findings show that fluid boundary layers control rotating convection systems, rather than Coriolis and buoyancy forces.
A new UCLA study found that light to moderate drinking among seniors reduced their odds of developing physical problems preventing common tasks. Alcohol consumption at light to moderate levels appears to have disability prevention benefits only in men and women in relatively good health.
A new national study shows that nearly 75 percent of patients hospitalized for a heart attack had cholesterol levels within recommended targets, but still at high risk. The study suggests that lowering guideline targets for LDL cholesterol and developing better treatments to raise HDL cholesterol may help reduce the number of patients ...
Researchers used innovative brain-scan technology developed at UCLA to help diagnose brain aging, often before symptoms appear. The study combined PET scans with patient-specific information on Alzheimer's risk and found that older age correlated with higher concentrations of abnormal protein deposits in the brain.
A new prototype cell phone uses holographic lens-free imaging to accurately identify smaller particles such as E. coli in saliva or blood samples, enabling rapid diagnosis of diseases like HIV and malaria. The technology also has potential for monitoring water quality and detecting hazardous microparticles in disaster situations.
Researchers successfully engineered E. coli to synthesize bacterial aromatic polyketides, a class of natural products including antibiotics like tetracycline and anticancer compounds like doxorubicin. The breakthrough allows for mass production of these vital compounds using simpler organisms.