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University of Wisconsin-Madison


Scientists find gene that protects against potato blight

Researchers at the University of Wisconsin-Madison have identified a gene that protects potatoes from late blight, a fungal pathogen responsible for the Irish potato famine. The discovery holds significant potential to save farmers hundreds of millions of dollars and benefit the environment by reducing toxic chemical applications.

SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateJul 14, 2003

UW researchers find second anthrax toxin receptor

Researchers at the University of Wisconsin-Madison have discovered a second anthrax toxin receptor, revealing that the toxin's entry into cells is more complicated than previously thought. This finding provides pharmaceutical companies with new ammunition to attack anthrax disease and offers potential therapeutic applications.

SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateApr 7, 2003

Brain images reveal effects of antidepressants

Researchers used functional magnetic resonance imaging (fMRI) to study the effects of antidepressant venlafaxine on clinically depressed patients. The study found that the drug produced robust alterations in the anterior cingulate area of the brain within two weeks, which may help predict treatment response.

SourceUniversity of Wisconsin-Madison·JournalAmerican Journal of Psychiatry·DateFeb 5, 2003

Study shows preschool can prevent abuse

A new study by University of Wisconsin-Madison researchers finds that preschool programs can significantly reduce the risk of childhood abuse and neglect. The study, which followed over 1,000 low-income children, found that those who attended a preschool program had a 52% lower rate of maltreatment compared to those who did not attend.

SourceUniversity of Wisconsin-Madison·JournalChild Development·DateJan 21, 2003

Researchers explain how the brain integrates head position and acoustics

Researchers discovered that fusiform cells in the cochlear nucleus integrate acoustic information with head and ear position information to pinpoint sound sources. The study found that synapses transmitting acoustic information are stable, while those carrying head and ear position information exhibit plasticity.

SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateDec 16, 2002

Even in middle age, cutting calories slows aging of the heart

Research published in PNAS found that caloric restriction can confer significant health benefits for the heart and extend its working life by exerting influence on the genetic program governing heart cells. In middle-aged mice, cutting calories prevented age-related genetic changes that damage heart cells and promote inflammation.

SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateOct 28, 2002

Novel form of vitamin D shown to grow bone

Researchers at the University of Wisconsin-Madison have discovered a potent Vitamin D analog, known as 2MD, which significantly increases bone density in rats with osteoporosis. The compound has shown no apparent toxicity and may become an alternative to hormone replacement therapy.

SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateSep 30, 2002

Subtract a gene and feasting mice add no fat

Scientists have created mice that can eat rich, high-fat diets without accumulating fat or risking diabetes. The mice lack the SCD-1 gene, which produces an enzyme required for fat tissue production. Instead of storing excess fat, the mice metabolize it, increasing energy expenditure and oxygen consumption.

SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateAug 12, 2002

Experience alters how we perceive emotion

A recent study by Seth Pollak found that children who have experienced physical abuse categorize facial expressions differently than non-abused children. Abused children identified more faces as being 'angry' rather than fearful or sad. This suggests that experience can shape how people perceive and understand emotions.

SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateJun 17, 2002

Traits link viruses from common cold to HIV

Scientists found that viruses causing diverse ailments like AIDS, common cold, and hepatitis share functional traits, linking large groups of viruses. These traits involve replication mechanisms and messenger RNA stages, suggesting a common ancestor among the viruses. The discovery bolsters prospects for broad-spectrum antiviral agents.

SourceUniversity of Wisconsin-Madison·JournalMolecular Cell·DateMar 25, 2002