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Vanderbilt University


Neurons cast votes to guide decision-making

Researchers found that certain neurons represent accumulation of evidence to a threshold and others represent evidence itself, driving decision-making. The study offers potential insights into psychological disorders, such as ADHD, where impairments in decision-making occur.

SourceVanderbilt University·JournalPsychological Review·DateOct 8, 2010

Newly discovered DNA repair mechanism

Researchers have discovered a new way that DNA-repair enzymes detect and fix damage to the chemical bases in the genetic code. The newly discovered mechanism detects and repairs a common form of DNA damage called alkylation, which is caused by environmental toxins and chemotherapy drugs.

SourceVanderbilt University·JournalNature·DateOct 3, 2010

Why surprises temporarily blind us

New research from Vanderbilt University reveals that our brains coordinate goal-directed and stimulus-driven attention when surprised. The inferior frontal junction plays a primary role in coordinating these two forms of attention, which may limit our conscious perception during unexpected events.

SourceVanderbilt University·JournalNature Neuroscience·DateMar 10, 2010

Worth the effort? Not if you're depressed

Researchers discovered that individuals with anhedonia, a core symptom of major depressive disorder, are less willing to make choices requiring greater effort in exchange for greater reward. This finding suggests a plausible connection between dopamine deficiency and reward processing in depression.

SourceVanderbilt University·JournalPLOS ONE·DateAug 12, 2009

Genetic marker linked to problem behaviors in adults with developmental disabilities

Researchers found a common genetic variation linked to aggression and destructive behavior in adults with developmental/intellectual disabilities. The study suggests that this variation may be associated with increased autism severity in individuals with the gene variant, highlighting the need for further research.

SourceVanderbilt University·JournalAmerican Journal on Intellectual and Developmental Disabilities·DateJul 21, 2009

Neural noise created during binocular rivalry

Researchers at Vanderbilt University discovered that neural noise weakens and degrades the brain's representation of an ignored stimulus, making it harder to distinguish between similar orientations. This 'neural noise' also broadens the range of interfering orientations during suppression, further reducing fidelity.

SourceVanderbilt University·JournalPsychological Science·DateJun 18, 2009

The day the universe froze

A new dark energy model proposes a cosmological phase transition, where the universe 'froze' about 11.5 billion years ago, causing it to expand at an ever-increasing rate. This theory attributes dark energy to a field dubbed quintessence, which acts as an antigravity agent and is spread uniformly throughout space.

SourceVanderbilt University·JournalPhysical Review D·DateMay 8, 2009

Chemists synthesize herbal alkaloid

A team of chemists at Vanderbilt University has successfully synthesized Serratezomine A, a potentially anti-cancer herbal alkaloid, in six years through an efficient process. This achievement could lead to the development of new treatments for cancer and other diseases.

SourceVanderbilt University·JournalJournal of the American Chemical Society·DateApr 15, 2009

Surface tension drives segregation within cell mixtures

Researchers have developed a new three-dimensional computer model that reveals surface tension plays a crucial role in cell sorting. The study found that when minority cells make up at least 25% of the mix, they are more likely to be in direct contact with other minority cells, enhancing the surface tension effect and allowing it to dr...

SourceVanderbilt University·JournalPhysical Review Letters·DateOct 6, 2008