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Wiley


Researchers develop new test for early osteoarthritis diagnosis

Researchers have developed a new diagnostic test that uses two markers found in the synovial fluid of patients' joints to differentiate osteoarthritis from inflammatory arthritis. The algorithm, based on the ratio of cartilage oligomeric matrix protein and interleukin-8, has been validated with high accuracy.

SourceWiley·JournalJournal of Orthopaedic Research®·DateDec 18, 2024

Porous crystals detect nitric oxide

A copper-containing, electrically conducting, two-dimensional metal–organic framework has been developed for the highly selective detection of nitric oxide. The material detects NO at room temperature with high sensitivity and selectivity, making it suitable for air quality monitoring and medical applications.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateDec 12, 2024

Oxygen redistribution in the brain

A team at Zhejiang University developed a novel strategy for early detection of high-altitude hypoxic brain injury using changes in oxygen content in brain regions over time. They found that brain regions with higher tolerance for hypoxia received less oxygen to support supply to more important areas.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateDec 6, 2024

Has childhood exposure to lead in gasoline contributed to mental illness?

Research published in the Journal of Child Psychology and Psychiatry found a significant association between childhood lead exposure and mental health symptoms. The study estimated that 151 million excess mental disorders were attributable to lead exposure by 2015, with differences most pronounced for people born between 1966 and 1986.

SourceWiley·JournalJournal of Child Psychology and Psychiatry·DateDec 4, 2024

Non-invasive imaging tests may lead to early sepsis detection

Researchers have developed a non-invasive strategy that assesses blood flow through skeletal muscle to detect early signs of sepsis. The technique, combining hyperspectral near-infrared spectroscopy and diffuse correlation spectroscopy, was tested in rodents and detected sepsis before vital organs were affected.

SourceWiley·JournalThe FASEB Journal·DateDec 4, 2024

Do soil microbes affect flowers’ ability to attract bees?

Research reveals that certain soil microbes can enhance flower size, resulting in increased bee visitations, but high colonization levels may lead to smaller flowers. The study focuses on arbuscular mycorrhizal fungi associations with plant roots and their impact on floral traits and pollinator interactions.

SourceWiley·JournalNew Phytologist·DateDec 4, 2024

Tumor cells suffer copper withdrawal

Researchers develop a method to remove copper from tumor cells, killing them. The nanofibers use copper-binding domains to grasp copper ions, disrupting cellular homeostasis and increasing oxidative stress.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateNov 20, 2024

Is therapeutic hypothermia an effective treatment for hypoxic-ischemic encephalopathy, a type of neurological dysfunction in newborns?

New research highlights additional therapies being tested for hypoxic-ischemic encephalopathy (HIE) in newborns, including agents blocking glutamate receptor activation and antioxidant drugs. While therapeutic hypothermia is effective in high-income countries, its efficacy is uncertain in low- and middle-income nations.

SourceWiley·JournalDevelopmental Medicine & Child Neurology·DateNov 20, 2024

Do area-wide social and environmental factors affect individuals’ risk of cognitive impairment?

Research identified community-level factors that may increase individuals' risk of cognitive impairment. Higher neighborhood disadvantage, air pollution, homicide rates, and less greenspace were associated with elevated odds of mild cognitive impairment. Completing schooling in a Southern US state also linked to increased risk.

SourceWiley·JournalJournal of the American Geriatrics Society·DateNov 20, 2024

Recycling batteries with citric acid

A novel citric-acid-based method has been developed to recycle metals from NCM cathodes with minimal energy usage and lower emissions. The process involves a relatively small amount of citric acid, allowing for efficient separation and reclamation of lithium, nickel, cobalt, and manganese metals.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateNov 15, 2024

Carbon recycling instead of plastic trash

A German research team has developed an electrocatalytic method for efficient degradation of polystyrene plastic waste, producing monomeric benzoyl products and short polymer chains. The process uses an inexpensive iron catalyst and can be powered by solar panels, combining recycling with green hydrogen production.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateNov 11, 2024

Does work-related stress compromise cardiovascular health?

A large multi-ethnic study found that work-related stress was associated with unfavorable cardiovascular health metrics, including lower odds of average and optimal health scores. The study's authors emphasize the need for longitudinal research on stress mechanisms and workplace interventions to improve employee well-being.

SourceWiley·JournalJournal of the American Heart Association·DateNov 6, 2024

Interstellar methane as progenitor of amino acids?

Research finds that gamma radiation can convert methane into glycine and other complex molecules, potentially playing a role in the origin of life. The study also reveals new strategies for industrial conversion of methane under mild conditions.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateNov 6, 2024

Do commercial ties influence ESG ratings?

A study published in Journal of Accounting Research finds that conflicts of interest from commercial ties lead to biased ESG ratings. ESG ratings for existing clients increased by 17.16% after the acquisitions, highlighting the need for regulation and investor awareness.

SourceWiley·JournalJournal of Accounting Research·DateNov 6, 2024

Molecular data storage

A new method allows direct access to specific bits in synthetic polymer data storage, enabling random access. The researchers encoded a sequence of ones and zeroes into a polymer chain, demonstrating the feasibility of storing and retrieving large amounts of data efficiently.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateOct 28, 2024

Can aerobic exercise help prevent brain fog caused by chemotherapy?

Women who started an aerobic exercise program during chemotherapy reported improved cognitive function and quality of life compared to those receiving standard care. The study found that while cognitive performance was similar after chemotherapy completion, the exercise program had a positive impact on self-reported cognitive function.

SourceWiley·JournalCancer·DateOct 21, 2024

A mushroom for colorectal cancer therapy

Researchers discovered a previously unknown class of compounds in the fungus Bipolaris victoriae S27 that effectively kill colorectal cancer cells. The most effective compound, bipoterpride No. 2, targets the DCTPP1 enzyme and shows promise as a potential new treatment option.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateOct 17, 2024

Can adrenaline auto-injectors prevent fatal anaphylaxis?

A recent review published in Clinical & Experimental Allergy suggests that intravenous adrenaline infusions can prevent fatal anaphylaxis, but adrenaline autoinjectors may have little impact in such deadly cases. Fatal anaphylaxis is rare, with a population incidence of 0.03–0.51 per million per year.

SourceWiley·JournalClinical & Experimental Allergy·DateOct 9, 2024

Octopus-inspired adhesive works well in wet conditions

Researchers developed an octopus-inspired adhesive with elastic, curved stalk and membrane that adheres to multiple surfaces in wet environments. The adhesive demonstrated strong attachment to complex objects and could be rapidly attached and released.

SourceWiley·JournalAdvanced Science·DateOct 9, 2024

Adhesive comes unglued on command

A new type of mussel-inspired adhesive has been developed that can be deactivated 'on command' through oxidation, allowing for efficient repair and recycling. The biobased adhesive loses its stickiness without becoming dramatically hydrophobic, making it easier to remove.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateSep 19, 2024

How do human and dog interactions affect the brain?

New research reveals that human-dog interactions synchronize brain activity, particularly in the frontal and parietal regions. Dogs with autism-associated genetic mutations show reduced synchronization, but treatment with LSD reverses this effect.

SourceWiley·JournalAdvanced Science·DateSep 11, 2024