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Wiley


Gout prevalence swells in US over last 2 decades

A new study finds that gout prevalence has risen significantly in the US adult population, affecting 8.3 million people, while hyperuricemia affects 43.3 million adults. The study suggests that managing modifiable risk factors like obesity and hypertension could help prevent further escalation of gout and hyperuricemia.

SourceWiley·JournalArthritis & Rheumatism·DateJul 28, 2011

Non-cocaine, topical anaesthetics can kill pain when repairing skin wounds

A systematic review of 32 trials involving 3128 patients found that cocaine-free topical anaesthetics substantially reduce pain without triggering serious side effects. These agents offer an attractive alternative to injecting pain killers into damaged tissue, making them easier and less painful for patients.

SourceWiley·JournalCochrane Database of Systematic Reviews·DateJul 27, 2011

Models show Coho salmon at risk in US urbanizing watersheds

Researchers used models to estimate the impact of urban land development on Coho salmon populations, predicting a significant decline in numbers due to spawner mortality syndrome. The study suggests that toxic chemical contaminants in urban storm water runoff may be the primary cause of the recurrent fish kills.

SourceWiley·JournalIntegrated Environmental Assessment and Management·DateJul 26, 2011

Local efforts can stem the increasing unnecessary cesarean sections

A systematic review found that nurse-led relaxation classes, birth preparation classes, and clinician feedback can decrease caesarean sections in low-risk pregnancies. However, prenatal education, computer patient decision-aids, and insurance reform have not shown significant effects on reducing cesarean section rates.

SourceWiley·JournalCochrane Database of Systematic Reviews·DateJul 26, 2011

Study suggests obesity accelerates progression of cirrhosis

A recent study found that increased body mass index (BMI) is an independent predictor of clinical decompensation in patients with compensated cirrhosis. The researchers suggest that weight reduction may improve patient outcomes and that measures to reduce BMI could improve the prognosis for patients with advanced liver disease.

SourceWiley·JournalHepatology·DateJul 21, 2011

Chinese culture encourages binge drinking in middle-aged men

A nationwide study in China found that 55.6% of men and 15% of women are current drinkers, with frequent binge drinking among males and women averaging 5.6 and 2.4 binges per year, respectively. Cultural factors, such as social pressure and entrenched customs, contribute to the problem.

SourceWiley·JournalAddiction·DateJul 18, 2011

HPV infection highly prevalent among organ transplant recipients

A study of 210 organ transplant recipients with previous SCC found that BetaPV infection is extremely common, with concordant presence of DNA and antibodies increasing the risk for SCC skin cancer. The findings may lead to novel preventative or therapeutic interventions for immunosuppressed individuals.

SourceWiley·JournalAmerican Journal of Transplantation·DateJul 12, 2011

Bladder cancer patients rarely receive recommended care

A new study reveals that nearly all high-grade noninvasive bladder cancer patients do not receive complete care as recommended by current guidelines. This suboptimal care has serious consequences, including increased risk of recurrence and progression to invasive tumors.

SourceWiley·JournalCancer·DateJul 11, 2011

An unhealthy lifestyle is associated with sexual dysfunction

A new study reveals that several unhealthy lifestyle factors, including weight problems, physical inactivity, and hard drug use, are associated with an increased risk of sexual dysfunctions in both men and women. The study found that up to 91% of women and 78% of men without a partner-related sex life had unhealthy lifestyles.

SourceWiley·JournalThe Journal of Sexual Medicine·DateJul 6, 2011

Botulinum toxin does not cure common forms of neck pain

A group of scientists reviewed nine trials involving 503 participants and found no evidence that Botulinum toxin injections reduce chronic neck pain. The study suggests that further research is needed to clarify whether the dose can be optimized for neck pain.

SourceWiley·JournalCochrane Database of Systematic Reviews·DateJul 5, 2011

Simple rapid diagnostic tests for malaria work well

A new Cochrane Systematic Review finds that Rapid Diagnostic Tests (RDTs) are highly accurate in detecting malaria parasites, with a success rate of at least 19 out of 20 cases. This development holds promise for improving diagnosis and treatment of malaria in resource-constrained settings.

SourceWiley·JournalCochrane Database of Systematic Reviews·DateJul 5, 2011

A gut-full of probiotics for your neurological well-being

Researchers propose a new field of microbial endocrinology linking probiotics to neurological function. Studies show that neurochemicals produced by gut microbes can influence behavior and immune response. Probiotic intestinal microbiota may deliver beneficial effects through direct uptake from the gut.

SourceWiley·JournalBioEssays·DateJul 5, 2011

Cutting down on salt doesn't reduce your chance of dying

A systematic review found that moderate salt reductions don't lower the likelihood of dying from cardiovascular disease. While reducing salt intake does lower blood pressure, it didn't significantly reduce the risk of heart disease or mortality. Experts call for more research to find effective ways to reduce salt intake.

SourceWiley·JournalCochrane Database of Systematic Reviews·DateJul 5, 2011

Vitamin D can help elderly women survive

A systematic review found that vitamin D3 supplementation increased survival in elderly women, particularly those at risk of falls and fractures. The study analyzed 50 randomized trials involving over 94,000 participants and suggested a reduced risk of mortality by approximately 6% with long-term treatment.

SourceWiley·JournalCochrane Database of Systematic Reviews·DateJul 5, 2011

Heart transplant patients at risk for serious skin cancers

A new study found that heart transplant patients are more likely to develop skin cancers, including cutaneous squamous cell carcinoma and melanoma. The incidence increased post-transplant by up to 30-fold, highlighting the need for improved patient education and screening.

SourceWiley·JournalAmerican Journal of Transplantation·DateJun 30, 2011

Gene variant increases fatty liver risk and fibrosis progression

A new study found that a specific gene variant, PNPLA3 rs738409, is linked to an increased risk of developing fatty liver and faster fibrosis progression in people with chronic hepatitis C. The study suggests this genetic predictor may also be used as a potential therapeutic target for treating the condition.

SourceWiley·JournalHepatology·DateJun 28, 2011