Articles tagged with Biochemical Engineering
Researchers have discovered that two distantly related RNA viruses perform chemical choreography in strikingly similar ways, forming a symmetrical icosahedral shell. This finding has potential applications in improving pharmaceutical delivery and engineering, as well as understanding protein folding mechanisms.
Researchers have developed an interactive metabolic map of bio-based chemicals, providing a versatile tool for easy assessment and optimization of synthetic pathways. The map enables exploration and analysis of complex networks of biological and/or chemical reactions, facilitating the design and production of desired chemicals.
Researchers at Lawrence Berkeley National Laboratory have created a new type of fuel that has higher energy density than traditional heavy-duty fuels. The biofuel, called POP-FAMEs, is produced by bacteria fed with plant matter and can significantly reduce greenhouse gas emissions when burned.
Researchers from Osaka University have developed a system to coat nematodes with hydrogel sheaths that can carry functional cargo. The study found that the sheaths protect the worms from UV light and hydrogen peroxide while allowing them to deliver anti-cancer agents to kill cancer cells in vitro.
Kobe University researchers successfully developed a tyrosine chassis in the yeast Pichia pastoris to produce various useful compounds with high yields. They introduced biosynthesis pathways for resveratrol, naringenin, norcoclaurine, and reticuline, achieving significant improvements in production rates.
Researchers at Rutgers University have created an automated tool to monitor biologic drugs during production, allowing for real-time quality control and enabling the production of biosimilars. The N-GLYcanyzer system can track changes in protein glycosylation and detect potential issues, improving drug safety and efficacy.
A new nanosensor platform uses machine learning to analyze spectral signatures of carbon nanotubes for early detection of ovarian cancer. The approach detects biomarkers and recognizes the cancer itself, offering a promising alternative to traditional methods.
A team of researchers developed a simple yet powerful strategy for creating new enzymes with novel reactivity that can produce valuable chemical compounds. They used photobiocatalysis to repurpose naturally occurring enzymes and achieved an enantioselective biocatalytic reaction.
Researchers developed long-lived biological computers using RNA, which can persist inside cells. Unlike DNA-based devices, these RNA circuits are dependable and versatile, enabling continuous production in living cells.
Researchers developed Inducible Directed Evolution (IDE), a new technique for controlling directed evolution in bacteria, allowing up to 30 gene modifications at a time. This approach enables finely tuned changes to bacteria, making it suitable for biopharmaceutical and chemical manufacturing industries.
Researchers have developed a protein-based gel that can deliver anti-inflammatory growth factor progranulin to affected joints, halting post-traumatic osteoarthritis (PTOA) onset and progression. The study found that the gel provides prolonged release of progranulin and inhibits chondrocyte catabolism.
A new technology developed by Aarhus University researchers uses sustainable biochar-based photocatalytic nanomaterial to break down PFAS into harmless substances. The process is powered by solar energy and produces non-toxic fluorides, CO2, and clean water.
Researchers at University of Maryland Baltimore County have developed a novel approach to modifying nanoparticles' surfaces to provide infusions with reduced negative reaction risks. By changing the core material, they reduced markers associated with infusion reactions, improving the effectiveness and safety of life-saving medications.
A Japanese collaborative team presents a novel method for tuning hydrodynamic interfacial instability through a thermodynamic parameter controlling liquid–liquid phase separation. They successfully predict pattern changes of a growing interface by applying the maximum entropy production principle.
Researchers will use C. thermocellum bacteria to better understand metabolism and production of cellulosic biofuels, aiming to reduce greenhouse gas emissions in heavy-duty transportation. The $1.2M grant will integrate enzyme assays, robotics, computer modeling, and advanced chemistry techniques.
Stanford researchers have developed a mini CRISPR genome editing system that is smaller and more efficient than existing versions. The new system, called CasMINI, has been successfully tested in human cells and shows promise for treating various diseases, including eye disease, organ degeneration, and genetic diseases.
A Colorado State University team has received a $3.2 million grant to develop ways to grow algae crops faster and improve their potential as a source of biofuels and other products.