Articles tagged with Autism
Researchers at Yale University used fMRI to identify three distinct 'neural signatures' in children with autism and their unaffected siblings. These patterns, including reduced activity in certain brain regions and enhanced compensatory activity, may help with earlier and more accurate diagnosis of autism spectrum disorder.
A new study published in Neurology suggests that children with autism are likely to continue experiencing handwriting problems into their teenage years. The research found that teenagers with autism scored significantly lower than those without autism on a handwriting assessment test.
Scientists successfully replicated autism in the lab using human induced pluripotent stem (iPS) cells derived from patients with Rett syndrome. The study revealed disease-specific cellular defects, such as reduced functional connections between neurons, which are reversible through insulin-like growth factor 1 (IGF-1) treatment.
Researchers at UCSD School of Medicine created functional neurons from patients with Rett syndrome, providing a new human cellular model for studying autism spectrum disorder. The neurons featured fewer synapses, reduced spine density, and altered calcium signaling, suggesting that synaptic deficiencies may not be permanent.
A significant genetic deletion on chromosome 17 has been identified as a risk factor for autism spectrum disorders and schizophrenia. The study found that patients with this deletion were at least 13.58 times more likely to develop ASD or schizophrenia.
A study analyzing genomic DNA from over 23,000 patients with ASD, developmental delay, or schizophrenia found a common deletion on chromosome 17 that increases the risk of developing either condition by at least 13.58 times.
Researchers at UCLA used brain imaging and genetic detective work to illustrate how genetic variants alter the brain, behavior, and learning. The discovery could lead to earlier detection of autism and targeted therapies to rebalance brain function.
A recent study found that total health care expenditures for children with autism spectrum disorders (ASDs) per 10,000 covered lives grew by 32.8% from $1,270,435 in 2000 to $1,686,938 in 2003. The treated prevalence of autism increased by 32.2% during the same period.
Researchers found that individuals with autism were more likely to believe in the vanishing ball trick illusion, despite having trouble interpreting social cues. The study suggests that people with autism may have difficulties allocating attention to the right place at the right time, which could impact their performance in social situ...
A new Université de Montreal study found that trained service dogs can significantly reduce stress hormone levels in autistic children, from an average of 33 problematic behaviors to just 25. The dogs also improved socialization skills and overall well-being for the children.
A team of scientists has made significant progress in understanding how the brain's 'hearing center' processes sound by mapping its acoustic space. They discovered that neurons within the auditory cortex respond to sounds based on their frequency, but also found an unexpected out-of-column pattern for some neurons.
A UCLA study found that exposing fetal neurons to high levels of the immune protein MHC leads to abnormal brain development in mice. This discovery may provide new insights into factors contributing to human neurological disorders like schizophrenia and autism.
Researchers at the University of Utah Health used MRI to identify areas where the left and right hemispheres of the brains of people with autism do not properly communicate. The study found functional connectivity abnormalities in the entire brain, adding to the understanding of this disorder.
A Queen's University study found autistic children are prone to telling white lies to avoid hurting others' feelings. In a test, most nodded or said yes instead of expressing disappointment with a soap gift.
Researchers created a new method called BLINC to directly observe protein-protein interactions in live brain cells. They found that synaptic activity affects the growth of a complex that mediates signaling into neurons, leading to excitatory synapse maturation.
A new study found that siblings of children with autism have more frequent language delays and subtle characteristics of the disorder. The research suggests that genetic factors can influence individuals to varying degrees, even if one child is diagnosed with autism while the other is not.
Eight new researchers will receive funding for their studies on autism spectrum disorders, including genetics, neuroscience and clinical research. The fellowships aim to support the growth of a promising cadre of young autism scientists.
Children with ADHD have more missing or duplicated segments of DNA compared to other children, suggesting a strong genetic link. The study also found significant overlap between these segments and genetic variants implicated in autism and schizophrenia.
New research from CAMH and SickKids reveals that males with specific alterations of DNA on their X-chromosome are at high risk of developing Autism Spectrum Disorder. The study found mutations in the PTCHD1 gene, which may disrupt brain development and contribute to autism.
Researchers identified a mutation in the PTCHD1 gene associated with about one percent of individuals with Autism Spectrum Disorders (ASDs) or intellectual disabilities, mostly males. The study suggests that this mutation may disrupt crucial developmental processes contributing to autism.
Researchers at University of South Florida (USF) are studying the impact of maternal infections on fetal brain development, aiming to prevent autism. Natural compounds like luteolin and diosmin may block detrimental effects of maternal infection on offspring's brains.
Most children develop contagious yawning by age 4, while those with autism spectrum disorders are less likely to yawn in response to others. Children with more severe autistic symptoms show the least yawn contagion, suggesting empathy and social cues may be delayed in development
A new study found that cognitive skills in children with autism spectrum disorder (ASD) vary from child to child and can improve over time. The research, conducted in Western Australia, assessed 37 children with ASD and 31 typically developing children at ages 5-6 and again three years later.
A small drug company, Seaside Therapeutics, is developing potential treatments for Fragile X syndrome and autism with secret funding from an anonymous wealthy family. Two of its drugs show promise in clinical trials as treatments for these diseases.
Researchers at UC San Diego identified misfolding of neuroligin-3 due to gene mutations, leading to trafficking deficiencies and abnormal neuron communications. The findings advance understanding of autism causes and may offer new drug therapies.
A new survey study found that parents of children with fragile X syndrome reported improvements in language use, attention spans, and behavior after treatment with the antibiotic minocycline. The study suggests that minocycline may be a promising targeted treatment for fragile X, prompting further clinical trials.
A study published in Archives of General Psychiatry found that toddlers with autism spend more time examining dynamic geometric patterns than social images. This preference was observed as early as 14 months in infants at-risk for autism, and was associated with a higher risk of developing an autism spectrum disorder.
A new study found that high-risk infants, those with a sibling with autism, showed infrequent gazing at caregivers when unprompted. Despite this, they demonstrated typical cause and effect learning skills. The study suggests that early exposure to simple cause and effect opportunities can aid in development.
A study by University of Montreal scientists found an increased frequency of severe de novo mutations in critical brain genes for both autism and schizophrenia. The research suggests that harmful de novo mutations may explain the high global incidences of these conditions.
A University of Nevada professor has conducted a six-year study revealing short-range over-connectivity in the outer layer of the brain's cortex in individuals with autism disorders. This finding supports early intervention behavioral therapies and may aid in sculpting out abnormal connections.
A study by Albert Einstein College of Medicine researchers provides concrete evidence that children with autism spectrum disorders process sensory information differently than typically developing children. The findings support decades of clinical observations and could lead to objective measures for evaluating the effectiveness of aut...
Researchers will design vision, speech, and wearable sensor technologies to analyze child behavior. The goal is to identify children at risk for autism and other developmental delays, with the potential to improve treatment delivery and outcomes.
Researchers will create novel tools for evaluating social interactions and behaviors to diagnose or treat autism. The project aims to develop a new discipline of computational behavioral science, transforming the study of human behavior with technologies like computer vision and machine learning.
A collaborative study examines a family with two rare genetic deletions, CNTNAP5 and DOCK4, which are associated with autism and reading difficulties. The research suggests that the CNTNAP5 deletion is linked to autism, while the DOCK4 deletion is co-segregated with reading difficulties.
A recent study published in Nature has found that certain genetic disturbances contribute to autism. The research revealed that Copy Number Variants (CNVs) are over-represented in individuals with autism. Furthermore, abnormalities in genes related to synapse development have been linked to the origin of autism.
Researchers at the Salk Institute found that individuals with Williams syndrome process spoken language differently from those with autism spectrum disorders, which has opposite social profiles. People with Williams syndrome exhibit an abnormally large N400 response indicating sensitivity to semantic aspects of language.
Researchers at King's College London have developed a pioneering new method of diagnosing autism in adults using a quick brain scan that takes just 15 minutes. This technique can identify adults with autism with high accuracy and may lead to the screening for autism spectrum disorders in children.
A recent study published in the Cochrane Database of Systematic Reviews found no evidence that antidepressants can treat autistic spectrum disorders in children. In fact, the medication may cause serious harm due to the small number of trials conducted and varying assessment methods.
The US Senate Committee on Environment & Public Works convened a special hearing on potential environmental health factors associated with autism spectrum disorders. Autism Speaks emphasizes the importance of research on environmental risk factors, noting a dramatic increase in autism prevalence over the last decade.
A new study reveals that parents of children with autism are more likely to divorce than couples with typically developing children, particularly after the child reaches adolescence and adulthood. The study found that marital strain may remain high in these later years due to ongoing parenting demands.
Researchers at Cardiff University are using advanced brain imaging techniques to investigate how people with autism process touch sensations. The study aims to provide a clearer understanding of sensory symptoms in autism and potentially lead to the development of new treatments.
A study found that relatives of individuals with autism exhibit abnormal eye movements and other sensorimotor impairments, similar to those seen in individuals with autism. These abnormalities are associated with brain pathways important for language skills, motor control, and executive function.
A new study finds that pre-verbal vocalizations of children with autism are distinctly different from those of typically developing children. The LENA system automatically analyzed 1,486 recordings and achieved 86% accuracy in distinguishing between the two groups.
A York University study discovered that the drug misoprostol interferes with neuronal cell communication by increasing calcium ions, which reduces cell extensions and prevents cells from communicating. This finding may have implications for understanding neurodevelopmental defects associated with autism.
A WSU study found that mothers of autistic children experience increased stress due to work demands and lack of flexibility. Nearly 60% have suffered financial problems in the past year, highlighting the need for workplace adaptations to support affected parents.
The University of Utah has received a $2.4 million, four-year grant to track the growth of autism spectrum disorders (ASDs) in Utah 8-year-olds. The grant is part of a nationwide effort to better understand the increasing prevalence of ASDs, which affect about one out of every 110 American children.
A recent study from Tel Aviv University found a strong link between IVF treatments and mild to moderate cases of autism. The research suggests that IVF may be solving one problem by creating another. Dr. Ditza Zachor's ongoing research aims to separate out risk factors and investigate the rate of autism in IVF populations.
Researchers generally agree that genetic variation findings should be shared with participants if clinically significant, but confidence levels vary across disciplines and conditions. The study highlights the complexity of this issue, suggesting that factors beyond scientific robustness influence researchers' decisions on disclosure.
A new study has identified multiple rare genes involved in regulating central nervous system processes, shedding light on the genetic causes of autism spectrum disorders. The research may lead to innovative treatments and a better understanding of the disorder.
A team of researchers from the University of Illinois Chicago has identified new autism susceptibility genes, including SHANK2, SYNGAP1 and DLGAP2, through an international collaboration with Autism Speaks. These findings suggest that multiple rare variants or genetic changes may contribute to the development of autism.
A recent study found rare genetic changes in autistic children that are often not present in their parents, occurring nearly 20% more frequently. The research, involving over 60 institutions worldwide, suggests that tiny errors during egg and sperm formation may contribute to autism.
Researchers identify four new autism susceptibility genes, including SHANK2 and SYNGAP1, which may lead to the development of new treatments. The study also found that individuals with autism tend to carry more genetic mutations than controls.
Researchers found rare genetic changes called copy number variants (CNVs) in nearly 2,300 people, which could account for up to 3.3% of autism cases. The study identified three new genes and pathways contributing to autism susceptibility.
Researchers have identified new autism susceptibility genes, including SHANK2 and SYNGAP1, which may lead to earlier diagnosis and better treatments. The study found that these genes are involved in synapse-related pathways and cellular proliferation, providing insights into possible common pathological mechanisms.
Researchers at Imperial College London have discovered a distinctive chemical fingerprint in the urine of children with autism, which could lead to a simple non-invasive test for early diagnosis. This finding has the potential to improve the progress of autistic children by enabling them to receive advanced behavioral therapy earlier.
Researchers at Heidelberg University Hospital have identified new mutations in the SHANK2 gene that contribute to autism and mental retardation. The study found that a correct inner structure of nerve cell synapses is necessary for normal language, social competence, and cognitive development.
Researchers at Mount Sinai School of Medicine identified a drug that improves communication between nerve cells in mice with Phelan-McDermid Syndrome. The treatment restores normal nerve cell function and adaptation to stimulation.
A new autism intervention for preschool children showed improvements in parent-child interaction, but failed to deliver a clinically significant reduction in autism symptoms. The study assessed 152 children aged 2-4 years and found that the PACT intervention led to enhanced communicative and social development.
A tightly controlled University of Rochester study found that eliminating gluten and casein from children with autism had no impact on their behavior, sleep or bowel patterns. Despite this, some subgroups of children may receive benefits from dietary changes, particularly those with significant gastrointestinal symptoms.
A study by Kennedy Krieger researchers found that 64% of children with ASD belong to a two-parent family, compared to 65% without ASD. The study suggests that parenting a child with autism can be stressful, but does not necessarily lead to divorce.