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Female genital mutilation could cause infertility

Researchers found a strong positive association between FGM and primary infertility, particularly with the most extensive form of the practice. The study suggests that women who have undergone FGM are at a higher risk of infertility due to anatomical changes, highlighting the need for preventive work against female genital mutilation.

SourceThe Lancet_DELETED·JournalThe Lancet·DateJul 28, 2005

PENN study emphasizes need for national guidelines for assisted reproductive technology programs

A new study by the University of Pennsylvania School of Medicine reveals inconsistencies in candidate-screening practices among US Assisted Reproductive Technology (ART) programs. The study found significant variation in reported likelihood of turning away candidates, with some programs accepting couples with addiction or welfare status.

SourceUniversity of Pennsylvania School of Medicine·JournalFertility and Sterility·DateJan 18, 2005

Infertility treatment affects oral health

A study suggests that women undergoing infertility treatment who have periodontal disease may experience higher levels of gingival inflammation and bleeding, which could impact the success of fertility treatments like ovulation induction medication. Maintaining good oral hygiene is crucial to prevent these issues.

SourceAmerican Academy of Periodontology·JournalJournal of Periodontology·DateJun 22, 2004

New obesity research highlighted at ENDO 2004

Recent studies have highlighted promising new treatments for obesity, including rimonabant's effectiveness in treating the condition. Additionally, researchers have discovered a lack of gut hormone PYY3-6 in obese individuals, leading to increased food intake and potential health risks associated with obesity.

Some infertile couples unaware of multiple birth risks

The study found that one in five women seeking treatment desired multiples over having a singleton, while fewer knew about the increased risk of cerebral palsy and infant death for twins. Infertile couples view twins as a 'bonus' to quickly build their families, but this increases risks such as preterm delivery.

SourceUniversity of Iowa·JournalFertility and Sterility·DateApr 21, 2004

Danish study finds that taking a long time to conceive is linked to problems at birth

A Danish study of over 56,000 births found that women trying to conceive for over a year were at increased risk of preterm delivery, term babies with low birthweight, and Caesarean section. The study also found significant associations between infertility and adverse birth outcomes in both treated and untreated infertile women.

Essential gene for male fertility found

Researchers at the University of Toronto have discovered a gene, Fkbp6, essential for male fertility but not female fertility. The study shows that the gene plays a critical role in sperm cell development and chromosome pairing, highlighting potential new principles in how cells control the number of chromosomes.

SourceUniversity of Toronto·JournalScience·DateMay 22, 2003

Teen girls with common hormonal disorder more concerned about fertility than peers

A new study found that teenage girls with polycystic ovary syndrome (PCOS) are significantly more worried about their future fertility compared to healthy age-mates. The study also revealed that PCOS patients have lower scores in quality of life questionnaire categories, particularly self-esteem and mental health.

SourceJohns Hopkins Medicine·JournalJournal of Pediatric and Adolescent Gynecology·DateFeb 13, 2003

Gene linked to infertility in mice

Researchers at Duke University Medical Center discovered a gene linked to male infertility in mice, which may also be associated with human infertility. The study found that the miwi gene plays an essential role in sperm production and its deficiency can lead to complete sterility in mice.

SourceDuke University Medical Center·JournalDevelopmental Cell·DateJun 6, 2002

Oral diabetes drug shows promise in preventing miscarriage in common infertility disorder

A study suggests that metformin, an oral diabetes drug, reduces the risk of miscarriage in women with Polycystic Ovary Syndrome (PCOS). Researchers found that 8.8% of pregnancies treated with metformin ended in miscarriage, compared to 41.9% in those not receiving the medication.

SourceNIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development·JournalThe Journal of Clinical Endocrinology & Metabolism·DateFeb 27, 2002

Weak sperm count does not always mean infertility, study says

A new study proposes revised guidelines for classifying semen samples as normal or abnormal, potentially rewriting laboratory standards used for 50 years. The research suggests that male infertility is not as clear-cut as current guidelines suggest, and that a 'gray zone' of borderline semen samples requires new treatment approaches.

SourceUniversity of Rochester Medical Center·JournalNew England Journal of Medicine·DateNov 7, 2001

Tissue proteolysis and male infertility

The targeted disruption of the PCI gene in mice leads to profound defects in sperm development and fertility. Human male infertility is also associated with a lack of PCI in seminal fluid, disrupting the balance of proteinases and proteinase inhibitors.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateDec 12, 2000

Home screening kits for common sexually acquired infection

Research suggests that home screening kits for Chlamydia, a common sexually transmitted infection, could be a useful tool in preventing lifelong infertility. The study found that men and women aged 18-35 were willing to participate in urine test kits, with higher participation rates among those from Avon than London.

SourceBMJ Specialty Journals·JournalSexually Transmitted Infections·DateMar 1, 2000

NICHD Network Identifies Most Effective Of A Series Of Infertility Treatments

Researchers found that treating women to ovulate and inseminating them through the uterus resulted in more pregnancies than other methods. The combination of superovulation and intrauterine insemination was deemed effective for infertile couples with no identifiable infertility factor and motile sperm.