Articles tagged with Infertility
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A recent survey found that most infertility patients support using leftover embryos for stem cell research, with 73% in favor. However, there is a growing demand from patients who want to sell their extra embryos to others, with 56% approving of the practice.
A recent study found that infants conceived through assisted fertilization had similar birth weights and gestational ages as those conceived naturally. However, they were more likely to experience perinatal deaths if their mother had previously struggled with infertility. The researchers suggest that the underlying causes of infertilit...
The use of intracytoplasmic sperm injection (ICSI) has increased nearly twice as much as standard IVF in Europe, according to new data. ICSI is now used more frequently in countries with southern European roots, despite lacking medical evidence that it provides better pregnancy rates than IVF.
A new low-cost IVF scheme aims to provide fertility treatment for women in developing countries, tackling high infertility rates and cultural barriers. The program offers affordable IVF for under $200, integrating it into existing healthcare services to address the growing need for fertility treatment.
Researchers are studying the architecture and behavior of ovaries to find new treatments for fertility disease and age-related infertility. A new imaging device, resembling a tiny drum, is being developed to measure ovary rigidity and understand symptoms of polycystic ovary syndrome.
Researchers identified gene mutations in FIGLA as a cause of premature ovarian failure, which can lead to infertility and other health issues. The study found three types of mutations in the gene, highlighting its importance in ovary function.
A team of scientists identified the TEX11 gene on the X chromosome as a key player in meiosis and male infertility. Disruption of this gene causes sterility in males and reduces female fecundity, highlighting the importance of sex chromosomes in fertility.
The National Institute of Child Health and Human Development has approved funding for a Center for Reproduction and Infertility Research at the University of Illinois. The center will support research on maternal-fetal interactions during early pregnancy and identify factors underlying infertility in women with endometriosis.
Field mice have sacrificed immunity protection to develop faster fertilization, resulting in instability of the sperm's acrosome. This process may provide insight into human infertility, as humans lack this rapid reaction.
Researchers at USC suggest epigenetics plays a role in male infertility, with abnormal DNA methylation linked to low sperm counts. The study finds high levels of methylation in sperm DNA from men with fertility issues, potentially leading to new treatments for male infertility.
A study published in Obstetrics & Gynecology found that women who followed a combination of five or more lifestyle factors experienced significantly lower rates of infertility due to ovulatory disorders. The key factors included dietary choices and physical activity, with higher scores associated with a lower risk of infertility.
Researchers at Michigan State University have identified a new gene, JY-1, necessary for embryonic development in dairy cows. The discovery may offer insights into the cause of infertility in women, who also experience single egg release and individual births, unlike mice which release multiple eggs.
Varicocele removal significantly improves testosterone levels in over two-thirds of men, leading to improved fertility and reduced symptoms of andropause such as low sex drive and depression.
Researchers at the University of Rochester confirm the X chromosome is a key factor in the origin of new species, with 60% of its genes causing infertility in hybrids. The large X-effect pushes newly formed species onto divergent evolutionary paths.
Scientists have identified a crucial gene, Jhdm2a, that triggers the final step of sperm cell formation. Mice lacking this gene exhibit significant male infertility symptoms. The study provides evidence that Jhdm2a controls expression of genes required for DNA packaging in sperm cells.
Researchers at UT Southwestern Medical Center have identified nearly 350 genes related to female fertility, providing a new understanding of the causes of female infertility. These discoveries may lead to improved diagnostic tests and tailored therapy for infertile women.
Researchers have identified radial spoke protein 44 (RSP44) as a key molecule in immune infertility, a condition causing the immune system to attack sperm. The discovery may lead to new diagnostic tools and treatments for this condition, which affects up to 12% of unexplained infertility cases in women.
A national study found that ICSI use for male-factor infertility has increased significantly, with a stable proportion of patients receiving treatment. States with mandated insurance coverage showed greater use of ICSI beyond male-factor infertility indications.
A recent study by Cardiff University found that social stress and marital stress increase over time for men with male factor infertility, while mental health decreases. Despite the common misconception that men experience more emotional distress when infertile, the research shows that men in all four categories suffer equally.
Researchers at The Feinstein Institute for Medical Research have isolated MIF, a substance in semen that regulates sperm maturity and fertility. Elevated or low levels of MIF were found to be associated with infertility, while high levels were linked to autoimmune diseases.
A survey of over 1,000 infertility patients found 60% willing to donate their frozen embryos for stem cell research. This could lead to 2000-3000 new stem cell lines, exceeding initial estimates.
The University of Illinois at Chicago has received a $7 million grant from the National Institute of Child Health and Human Development to study endometriosis and its effects on fertility. The research aims to develop new therapies and better understand embryo implantation and pregnancy.
Researchers identified a dominant gene mutation in Dmc1 that causes male infertility in mice. The study provides insights into the genetic causes of infertility in humans and suggests potential applications for fertility treatments.
A new study published in International Braz J Urol found that exposure to hot baths or hot tubs can lead to male infertility. However, the effects can be reversible if the practice is discontinued for at least three months. The study showed a significant increase in sperm motility among responders, with a mean increase of 491 percent a...
Researchers found that consuming whole fat milk and eating ice cream reduces the risk of anovulatory infertility in women trying to become pregnant. In contrast, a diet consisting of low-fat dairy products increases the risk by up to 85%. Women are advised to switch from low-fat to high-fat dairy foods to improve fertility.
A new study reveals that embolization, a minimally invasive treatment for varicoceles, significantly improves sperm motility and count in infertile men. Six months after treatment, 26% of couples achieved a pregnancy, with high sperm motility before the procedure being the key predictor of success.
A mathematical model predicts that IVF treatment is more efficient and likely to result in pregnancy after the first trial. Offering IVF first is more cost-effective than offering IUI alone or followed by IVF if IUI fails, saving £174,200 for an additional 54 couples.
Researchers discovered higher concentrations of nitric oxide in the seminal plasma of infertile patients compared to healthy men. High NO levels were correlated with greater sperm DNA damage, while low NO levels improved sperm motility.
Infertility risk in women with ulcerative colitis increases significantly after ileal pouch anal anastomosis surgery, according to a meta-analysis. The study found that the risk of infertility tripled to 48% after the procedure, with no obvious factors contributing to this increased risk.
A new study examining 911 babies treated with either letrozole or clomiphene citrate found no statistically significant difference in major and minor malformations or chromosomal abnormalities between the two groups. The findings confirm concerns about a link between letrozole and birth defects are unfounded.
A study on Maori infertility aims to address the lack of quality information on the issue, which is affecting declining family sizes among Maori. The research will gather views from different Maori groups to inform improvements in reproductive healthcare.
George Orwell's struggles with tuberculosis and possible infertility contributed to the dark tone of 1984, but also gave him a unique perspective on human suffering. His writing became more universal as he drew from his own experiences with illness.
Researchers discovered a specific endometrial target gene, GlcNAc-6-OST, plays a crucial role in the implantation process. Increasing estrogen and progesterone levels enhances this gene's expression, facilitating L-selectin ligand production and successful implantation.
Researchers found a strong positive association between FGM and primary infertility, particularly with the most extensive form of the practice. The study suggests that women who have undergone FGM are at a higher risk of infertility due to anatomical changes, highlighting the need for preventive work against female genital mutilation.
A report from the ESHRE committee reveals a significant rise in ICSI cycles, overtaking IVF techniques as the most commonly used assisted reproductive technology. The increase in ICSI cycles may be linked to shifting causes of infertility, with male subfertility potentially on the rise.
A study found that IVF's benefits, including increased live births and reduced multiple births, outweigh its costs. The 'production' cost of a pregnancy rose from €14,000 to €22,000 between 1994 and 2002.
A leading researcher is presenting data on a new infertility drug that has shown promising results in reducing miscarriage rates in mice. The drug, PV903, contains an active ingredient found in semen and aims to instruct the mother's immune system to tolerate the fetus.
A new study by Dr. Jane Dimmitt Champion and her team found that minority adolescent women with a history of sexual/physical abuse are at higher risk of pelvic inflammatory disease and HIV/STDs. With better screening, these health problems could be decreased.
Scientists discovered that mice lacking LPA receptors experience fertility problems, with embryos failing to implant in the womb. This finding may lead to new insights into female infertility and potential therapeutic interventions for human fertility issues.
A study on the MSY2 protein found that its absence in mice leads to male and female infertility. The researchers aim to develop new non-hormonal contraceptives using Contrin, a human equivalent of MSY2. This discovery holds promise for targeted fertility treatments and could lead to innovative contraceptive options.
A study by UCSD researchers suggests that BMP-15 plays a crucial role in determining ovulation quota and litter size in mammals. The team found that BMP-15 is produced normally in humans but degraded in mice, leading to increased egg production and ovulation.
Scientists at Rockefeller University have discovered a key event in the maturation of sperm that is extremely sensitive and could be targeted to improve fertility or develop a male contraceptive. The research found that mice missing a gene called Septin 4 are sterile, with sperm defects similar to human conditions like 'droplet sperm',
A study found that 41% of infertile women would use preimplantation sex selection at no cost, with racial groups having a stronger preference for selecting the sex of their child. Women without children and those seeking family balancing were more likely to choose nonmedical sex selection.
A Dutch study found that lesbian couples and more privileged heterosexual parents tend to favor openness, while anonymous donors are often associated with lower socioeconomic status and secrecy. The UK study also revealed that many parents feel no reason to disclose information or protect family members.
A new study by the University of Pennsylvania School of Medicine reveals inconsistencies in candidate-screening practices among US Assisted Reproductive Technology (ART) programs. The study found significant variation in reported likelihood of turning away candidates, with some programs accepting couples with addiction or welfare status.
The NIH has awarded $68 million to 1,407 new student loan repayment contracts in Fiscal Year 2004. These programs provide up to $35,000 of qualified educational debt repayment for health professionals pursuing careers in clinical, pediatric, contraception and infertility, or health disparities research.
A study by Ann H. Partridge et al highlights the need for better patient-physician communication about fertility in young breast cancer patients. Fifty-seven percent of patients reported being very concerned about becoming infertile, with 29% influencing their treatment decisions.
Mayo Clinic researchers discovered a gene, BubR1, that regulates physical aging and fertility. The study found that mice with low levels of the protein age prematurely and develop reproductive disorders.
A study suggests that women undergoing infertility treatment who have periodontal disease may experience higher levels of gingival inflammation and bleeding, which could impact the success of fertility treatments like ovulation induction medication. Maintaining good oral hygiene is crucial to prevent these issues.
Recent studies have highlighted promising new treatments for obesity, including rimonabant's effectiveness in treating the condition. Additionally, researchers have discovered a lack of gut hormone PYY3-6 in obese individuals, leading to increased food intake and potential health risks associated with obesity.
Researchers found decreased pregnancy rates in couples where the man had IgG antibodies, a marker of previous or persistent infection by Chlamydia trachomatis. For those infertile couples with IgG antibodies, 6.8% of women and 7.1% of men carried Chlamydia DNA in their urine, suggesting active infection.
The study found that one in five women seeking treatment desired multiples over having a singleton, while fewer knew about the increased risk of cerebral palsy and infant death for twins. Infertile couples view twins as a 'bonus' to quickly build their families, but this increases risks such as preterm delivery.
A new study reveals that young breast cancer survivors are worried about their fertility and that healthcare providers often fail to address these concerns. The study's findings highlight the need for better education and support for women with breast cancer who want to have children.
A study led by Dr. Lawrence C. Layman aims to identify genetic mutations contributing to delayed puberty, which may lead to better infertility treatment and birth control options. By analyzing the function of hundreds of genes, researchers hope to uncover potential treatments for this condition, which affects about 1% of the population.
A Danish study of over 56,000 births found that women trying to conceive for over a year were at increased risk of preterm delivery, term babies with low birthweight, and Caesarean section. The study also found significant associations between infertility and adverse birth outcomes in both treated and untreated infertile women.
Scientists at Emory University Health Sciences Center have identified a new sperm protein called SED1 that plays a critical role in the initial association between sperm and egg during fertilization. Mice without this protein had reduced fertility despite normal sperm characteristics, highlighting its importance in successful binding.
Infertility in developing countries is largely due to preventable causes such as sexually transmitted diseases. Accessible preventative treatments can help tackle the issue, reducing stigma and social ostracization.
A Stanford-led team discovered 12 genes relevant to endometriosis-related infertility, offering potential targets for new treatments. These findings could lead to improved diagnosis and treatment of the disease, reducing reliance on surgery and medication.
Researchers at the University of Toronto have discovered a gene, Fkbp6, essential for male fertility but not female fertility. The study shows that the gene plays a critical role in sperm cell development and chromosome pairing, highlighting potential new principles in how cells control the number of chromosomes.
A study of 800 young male army recruits found that nearly 10% could have chlamydia infection, with a higher proportion than previously reported having asymptomatic cases. Infected men were equally active sexually as the general population.