Articles tagged with Pregnancy
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A recent study of 2,261 infants found no significant adverse effects on neurodevelopment after in utero exposure to COVID-19 vaccination. The research suggests that maternal COVID-19 vaccination is safe for infant development up to 18 months.
Researchers used 'mini-placentas' to understand how the placenta interacts with the uterus, which is critical for fetal growth and development. The study identified key proteins involved in successful implantation and found clues on how pre-eclampsia occurs.
A large study of 401,000 neonates found prenatal opioid exposure was associated with an increased risk of infection, eczema and dermatitis, and asthma. The findings highlight the need for further research into opioid-induced immune changes during pregnancy.
A new study found that states with restrictive abortion laws had a 16% increased infant mortality rate compared to those with more comprehensive reproductive healthcare. Demographic factors such as low education attainment and inadequate prenatal care also contributed to elevated IMR.
A new study found that e-cigarettes are more commonly used by pregnant smokers than nicotine patches, and regular use of nicotine products is not associated with adverse effects on mothers or babies. The study suggests that e-cigarettes can be a safe stop-smoking aid for pregnant women.
A new study links increased acetaminophen use during pregnancy, particularly in the second trimester, to noticeable increases in attention and behavior problems in 2-, 3- and 4-year-olds. The study found modest but notable increases in attention-related issues and ADHD-type behaviors with increasing acetaminophen use.
The MAMAH trial found that preventive treatment with DHA-PPQ significantly reduces the risk of malaria infection and disease in pregnant women living with HIV. Women in the treatment group had almost eight times lower risk of clinical malaria and half the risk of becoming infected compared to the placebo group.
Research from the University of Pennsylvania School of Medicine sheds light on two rare heart conditions, dilated cardiomyopathy and peripartum cardiomyopathy. The study reveals that truncated titin proteins are present in hearts affected by DCM, indicating a potential link between genetic variants and disease development.
Researchers created a single-cell atlas of the human placenta, revealing changes in gene expression patterns among cell types. The study found that cells most affected by labor were in chorioamniotic membranes and generated inflammatory signaling.
New research from the University of Bristol found that exposure to high humidity and temperature during pregnancy can influence blood pressure changes in children. The study analyzed over 7,000 participants and found a steeper increase in blood pressure with higher relative humidity and a slower increase with higher temperature.
A new study found that low-dose calcium supplementation (500mg per day) was as effective as high-dose supplementation (1,500mg per day) in preventing preeclampsia, with no significant difference in preterm birth rates. The findings provide an opportunity to revise the WHO's current recommendation for pregnant women with low-calcium diets.
A large cohort study in Sweden found that women diagnosed with perinatal depression are twice as likely to die from natural or unnatural causes, with an increased risk of death peaking in the month after diagnosis. The study suggests that providing better screening and care for these women is crucial.
Researchers from Binghamton University are unraveling the workings of Group B Strep (GBS) infections, which could someday lead to a vaccine. They have identified a novel protein that could serve as a vaccine candidate to fight this bacterium, impacting women's reproductive health and neonatal outcomes.
Researchers found that ASCOT reverses some age-related protein expression changes, enriching processes related to the complement cascade and immune system in patients with poor ovarian response. In contrast, patients with premature ovarian insufficiency showed enrichment in responses to oxygen-containing compounds and growth hormones.
Women with autoimmune disease are 30% more likely to experience perinatal depression, while those with perinatal depression have a 30% higher risk of developing an autoimmune disease. The strongest association is seen with multiple sclerosis.
A recent study published by the Mayo Clinic found that an AI-enabled digital stethoscope can detect peripartum cardiomyopathy, a potentially life-threatening condition, more accurately than regular care. The researchers identified twice as many cases using the AI-powered tool.
A recent genetic study has made a significant leap forward in understanding gestational diabetes by identifying nine novel genetic regions linked to the condition. The study, conducted on over 12,000 patients and 131,000 female controls, has nearly tripled the number of known genetic areas associated with gestational diabetes.
A research team developed a novel blood test called desNIPT to screen pregnant women for genetic diseases in their unborn children. The test has demonstrated effectiveness in identifying alterations in fetal genes, similar to invasive procedures like chorionic villus sampling or amniocentesis.
Researchers from UC Davis School of Medicine and MIND Institute found that imbalances in folic acid and vitamin B12 can alter brain development in mice. High folic acid intake, even within recommended guidelines, may cause neurodevelopmental issues in offspring.
A study published in iScience found that DEET can affect meiosis, leading to abnormal chromosome structure and reduced egg cell quality. This raises concerns about the potential reproductive effects of DEET-containing products in humans. Further research is needed to confirm these findings and inform recommendations for balancing disea...
A new study from Mass General Brigham researchers found that women who experienced more preconception stress had higher blood sugar levels during pregnancy, a predictor of current and long-term cardiovascular health. The study also discovered that socioeconomic status was associated with preconception stress and blood glucose levels.
A new study published in the Journal of the Endocrine Society found that stressed women undergoing fertility treatment may experience higher blood sugar levels during pregnancy, which can lead to weaker cardiovascular health. Women who conceived through intrauterine insemination (IUI) had higher stress and blood sugar levels than those...
A team at Massachusetts General Hospital identified six proteins involved in cardiovascular and inflammatory processes that contribute to or protect against hypertensive disorders of pregnancy. These findings suggest different pathways involved in the development of these diseases.
A new study found that increasing acetaminophen use during pregnancy is associated with language delays in early childhood, including smaller vocabulary scores and shorter mean length of utterance. The study suggests that fetal brain development is critical during the second and third trimesters.
A new two-year study will examine the impact of environmental factors on children's health, including those with disabilities. The researchers aim to recruit a diverse population of pregnant people and their children to understand the bidirectional relationship between mother and child.
A nationwide case-time-control study found an association between benzodiazepine use during pregnancy and an increased risk of miscarriage. The results suggest that healthcare professionals should carefully weigh the benefits and risks of using benzodiazepines to treat psychiatric and sleep disorders in pregnant women.
A Mediterranean diet has been found to be a straightforward and effective approach for improving IVF success rates, with high intakes of fruits, vegetables, whole grains, and omega-3 fatty acids. The diet's benefits were seen in both embryo development and pregnancy outcomes, even after just six weeks of implementation.
Hyperemesis gravidarum is a debilitating condition causing intense vomiting, hair loss, and mental health issues. Researcher Cheryl Beck studied 33 blog posts from women in Australia, finding six consistent themes: physical debilitation, emotional distress, and financial struggles.
Researchers at Boston Children's Hospital developed a predictive model for accessing prenatal care services in rural Amhara, Ethiopia. The model incorporated data on education, income source, diet, and history of previous pregnancies, identifying factors that predict failure to attend prenatal care visits.
A malaria drug combination could counteract the negative effects of malnutrition on the female digestive tract, leading to improved birth outcomes. The research used a human organ chip model to demonstrate the potential benefits of this treatment.
A new study published in PLOS Medicine found no association between assisted reproductive technologies and body mass index in children, except when using frozen embryos. The study analyzed data from Denmark and other countries, providing insights into the health outcomes of children born through assisted reproductive technologies.
A study published in Environmental Health Perspectives found that exposure to phthalates can lower the odds of getting pregnant, but not lead to pregnancy loss. The researchers also discovered associations between preconception phthalate exposure and changes in women's reproductive hormones, inflammation, and oxidative stress.
Researchers at Texas A&M University found that it takes over a month for negative alcohol effects to wear off, and fathers' sperm are still negatively impacted by drinking even during the withdrawal process. The study suggests that men should abstain from alcohol at least three months prior to conceiving.
Researchers will compare two healthcare delivery models focusing on early detection and control of postpartum hypertension and social/mental health factors. The study aims to improve birth outcomes for women and children in underserved communities through a patient-centered approach.
Participating in baby massage has been linked to lower rates of postnatal depression and improved parent-child interactions. A systematic review found that mother-led infant massage can have a positive impact on maternal mental health and relationships.
A recent study published in JAMA Network Open analyzed data from 10,000 US adolescents and found a significant increase in e-cigarette use during late pregnancy. However, the study revealed no statistically significant association between e-cigarette use and an increased risk of small-for-gestational-age birth among adolescents.
A Cambridge-led study discovered the cause of pregnancy sickness, attributing it to a hormone produced by the fetus called GDF15. The severity of nausea and vomiting depends on the amount of GDF15 produced and the mother's sensitivity to it. Building up tolerance to GDF15 before pregnancy may prevent sickness.
A new study finds that a hormone produced by the fetus and a mother's sensitivity to it are the causes behind nausea and vomiting during pregnancy. Lowering GDF15 levels or pre-exposing women to the hormone may mitigate symptoms, providing potential ways to prevent extreme forms of pregnancy sickness.
A multicenter observational cohort study found that cannabis exposure was associated with a higher risk of small-for-gestational-age birth, medically indicated preterm birth, stillbirth, and hypertensive disorders of pregnancy. The risk was particularly pronounced among those who continued to use cannabis beyond the first trimester.
Using metformin plus insulin to treat preexisting type 2 or gestational diabetes diagnosed early in pregnancy did not show a reduction in composite neonatal adverse outcomes. The study suggests that the effect of reducing large-for-gestational-age infant risk after adding metformin to insulin warrants further investigation.
A new study found no increased risk of major congenital malformations in infants exposed to second-line non-insulin antidiabetic medications during pregnancy compared to those treated with insulin. The study examined over 3.5 million pregnancies and provided reassurance on the safety of these medications for fetuses.
Embryos with morphologically non-good-quality blastocytes and those from women aged ≥ 35 years showed lower rates of implantation, clinical pregnancy, ongoing pregnancy, and live births after blastocyst shrinkage. Post-warming blastocyst shrinkage adversely affects ART outcomes.
New research reveals that early life gene epimutations in the BRCA1 gene may increase the risk of triple-negative breast cancer (TNBC). The study found that these epimutations occurred twice as often in girls than boys and were associated with a higher risk of TNBC, particularly in women who experienced pregnancy-related changes.
Women who have had a C-section may face difficulties conceiving due to reduced fertility and increased risk of labor complications. The study found that women with fertility problems also had more C-sections.
A study found that patients with hormone receptor-positive breast cancer who paused endocrine therapy to conceive did not experience worse short-term recurrence rates. Cryopreserved embryo transfer was associated with higher pregnancy rates, and younger age and menstrual cycles returning after pausing therapy were linked to improved ou...
A retrospective cohort study of 4,732 BRCA carriers found that pregnancy following breast cancer was not associated with decreased disease-free survival. 1 in 5 patients conceived within 10 years after diagnosis.
A NIH-funded study found associations between maternal prenatal inflammation and children's attention, anxiety, depression, and aggression. The research used the Child Behavior Checklist to measure aggressive behavior, anxiety/depression, and attention problems in 4,595 participants aged 6-18 years.
A pregnant patient with severe vasospastic angina successfully carried a healthy baby to full term after starting treatment with calcium channel blockers. The case highlights the importance of careful diagnosis and treatment, which can alleviate symptoms and prevent complications.
A new study found that the Protecting Life in Global Health Assistance policy reduced provision and use of contraceptives, as well as community health volunteer services, in African countries. This policy, formerly known as the Mexico City Policy, had detrimental effects on family planning service delivery and utilization.
A study published in PLOS Medicine found that 90% of pregnant women in high-income countries lack key vitamins necessary for healthy pregnancies and fetal development. The situation is expected to worsen as more people adopt plant-based diets, leading to increased risk of nutrient deficiencies.
A new study from the University of Wisconsin-Madison found that individuals born in dry counties due to Prohibition-era laws lived longer, with an average additional lifespan of approximately 1.7 years. This increase in longevity is equivalent to nearly 15% of the overall life expectancy improvements for those born between 1900-1930.
Women who underwent bariatric surgery had lower pregnancy weight gain compared to controls with similar early pregnancy characteristics. The study found no difference in weight gain based on surgical procedure or surgery-to-conception interval, but suggested a potential benefit for women with shorter intervals.
A recent study found that nearly all pregnant women have low levels of essential vitamins and minerals, with some developing deficiencies in late pregnancy. Supplementing with over-the-counter multivitamins significantly reduced nutrient deficiencies before and during pregnancy.
Researchers discovered how biological information travels between mothers and babies during pregnancy. Microscopic extracellular vesicles, produced by placental cells, act as a protective mechanism transporting important biological information to emerging neurons.
Researchers now have access to a large amount of diet information collected from over 33,000 pregnancies and 31,000 children. This de-identified data, available through the National Institute of Child Health and Human Development's DASH Hub, will help answer important questions about nutrition and child health.
Research highlights association between maternal depressive symptoms and reduced fetal growth during critical rapid growth stage before delivery. Early screening for depressive disorders in pregnant women may be crucial for promoting healthy fetal development.
In a significant breakthrough, research revealed that macrophages 'eat' pancreatic beta cells to regulate insulin levels after pregnancy. This process helps maintain normal blood glucose levels.
Researchers found that prenatal vitamins provided short-term benefits, while postnatal vitamins offered sustained impacts on breast milk B-12 adequacy. Both types of supplements supported healthy growth and development in infants.
A study published in Science Advances found that abnormal cell stress in the placenta's syncytiotrophoblast layer may lead to preeclampsia. Researchers also developed a mouse model to demonstrate the effects of this stress, showing similar signs of high blood pressure and kidney damage.
Researchers at Gladstone Institutes have identified cells and molecules that go awry in the developing hearts of fetuses in women with diabetes, leading to higher levels of retinoic acid activity. The study could eventually lead to interventions to lower heart malformations risk in babies born to women with diabetes.