Articles tagged with Disease Prevention
A family-based approach to lifestyle interventions significantly improved weight management and obesity-related health outcomes among individuals with a family history of premature coronary heart disease. The study found that participants experienced an average reduction of 2.61 kg in weight, 1.06 kg/m² in BMI, and 4.17 cm in waist cir...
A large study suggests that patients at high risk of heart attacks and strokes should be treated immediately with a combination of a statin and ezetimibe, rather than statins alone. This combination therapy significantly reduces the risk of death from any cause and major adverse cardiovascular events.
A Mount Sinai-led team has discovered a link between gamma delta intraepithelial lymphocytes and the development of Crohn's disease. By analyzing a mouse model, they found that impaired communication between these cells led to inflammation in the lower small intestine.
The European Centre for Disease Prevention and Control (ECDC) reports a rise in tuberculosis cases among children and adolescents in the EU/EEA, with a slight increase in the notification rate from 2.0 to 2.5 per 100,000 population. The highest proportion of paediatric TB was observed in children aged 1 to 4 years old.
A deep learning model analyzes breast arterial calcification and translates results into a cardiovascular risk score, helping identify patients at higher risk of heart disease. The tool is particularly useful for younger women, who can benefit from early interventions.
A clinical trial shows that removing amyloid plaques from the brain can delay Alzheimer's symptoms, supporting the amyloid hypothesis. The treatment reduced the risk of developing dementia in people destined to develop early-onset Alzheimer's disease.
Researchers have identified a type of immune cell that produces extracellular matrix, strengthening the skin's defensive function and maintaining its integrity. This discovery may lead to new strategies for treating skin diseases, inflammation, diabetes, and age-related conditions.
The Endocrine Society calls for the reinstatement of the Diabetes Prevention Program, which has been halted by government funding cuts. The program, spanning three decades, found that lifestyle changes or metformin could prevent or delay type 2 diabetes in at-risk individuals, with a notable 58% risk reduction through 5%-7% weight loss.
Researchers found that patients who received non-compliant care had more complex medical conditions and were more likely to present with unusual symptoms. The study's findings challenge the assumption that SEP-1 compliant care is associated with better survival, highlighting the need for risk-adjusted outcome measures.
CHEST MedCast offers over 400 videos and podcasts with personalized content recommendations, available on-demand and at any time from any device. The platform features an algorithm-based recommendation engine and up to 100 available CME credits/MOC points.
Researchers found that lifestyle and health factors linked with heart disease have a stronger impact on women than men. Women were more likely to have fewer negative risk factors but faced a greater increase in cardiovascular events if they had more negative risk factors compared to men.
A longitudinal study of Hispanic mothers found that women with normal blood pressure levels during pregnancy but no mid-pregnancy drop in blood pressure face an increased risk of developing hypertension after giving birth. Tracking blood pressure patterns during pregnancy may help identify these women and prevent cardiovascular disease.
Researchers at the University of Virginia Health System have developed a computational tool called LogiRx that can predict how drugs will affect biological processes in the body. The tool has demonstrated its potential by identifying a promising candidate to prevent heart failure, a leading cause of death worldwide.
Researchers argue that the current paradigm of cancer as a genetic disease is unproductive due to inconsistencies in sequencing data. Alternative paradigms considering non-genetic processes, such as disruptions in gene regulatory networks and tissue organization, are proposed to guide future experiments.
Thomas Jefferson University has initiated a phase 1 clinical trial for a Lassa virus (LASV) vaccine, currently enrolling healthy volunteers. The vaccine's safety and immunogenicity will be assessed in both the rabies virus and LASV.
A recent cohort study published in JAMA Internal Medicine found that statin use was associated with a reduced risk of hepatocellular carcinoma and hepatic decompensation in patients with chronic liver disease. This suggests that statins may play a role in preventing the progression of liver disease and reducing the risk of liver cancer.
A Northwestern University study found significant disparities in glaucoma monitoring, with rural and economically distressed communities facing barriers to care. The study identified strategies to improve access, including expanding tele-ophthalmology services, home monitoring technology, and financial support.
Oropouche virus has been reported in travellers from Canada and the US who visited Bolivia, Brazil, Peru, and Cuba, with symptoms including fever, chills, headache, and muscle aches. The risk of miscarriage and microcephaly is high for pregnant individuals, prompting cautionary measures.
A Phase 1 clinical trial is enrolling up to 55 healthy adults to test the safety and immunogenicity of a candidate Lassa vaccine. The trial aims to prevent Lassa fever, a viral hemorrhagic disease that can cause permanent hearing loss.
Consuming raw milk and its products increases the risk of foodborne illness, including from Salmonella, E. coli, and Campylobacter. The Centers for Disease Control and Prevention have detected H5N1 bird flu in raw milk, posing a risk to human health.
A novel subset of progenitor cells, called high-risk MSCs, reside in the stroma and promote DNA damage and tumor growth. These cells play a critical role in the initiation of ovarian cancer, particularly in older women or those with BRCA mutations.
A study has established the importance of immunoglobulin A in generating a response to pneumonia vaccines. The research found that poor regulation of gut microbiota can lead to an inadequate immune response, leaving individuals vulnerable to respiratory infections.
Researchers discovered that exposure to similar behaviors within a person's social network is the most significant factor predicting individual prevention behaviors. Household-level interventions targeting entire families could result in more effective prevention strategies.
A new study found that limiting TV viewing to one hour or less daily may help offset an increased risk of heart and blood vessel diseases for people with a genetic risk for Type 2 diabetes. This suggests that reducing TV watching could serve as a key behavioral target for preventing atherosclerotic cardiovascular diseases linked to Typ...
A recent study by Oregon Health & Science University and Weill Cornell Medicine has found that CMV lacking a certain viral protein complex can still be transmitted and cause significant harm to the developing fetus. The research suggests that additional vaccine targets need to be identified and explored to provide superior protection.
A cross-sectional survey revealed high costs, inadequate training, and poor financing as major challenges to gastrointestinal endoscopy practice in Nigeria. Locally developed innovations have eased the practice, preventing it from collapsing.
A national survey found that nearly 90% of Americans believe eating healthy foods is crucial for preventing conditions like obesity and type-2 diabetes. More than half would participate in produce prescriptions or medically tailored meal programs if offered through their healthcare providers.
A major clinical trial has identified ensitrelvir as an effective medication to prevent symptomatic COVID-19 in people exposed within households. The trial showed a 67% reduction in risk of illness among participants taking the antiviral compared to those given a placebo.
The American Heart Association emphasizes the importance of brain health, citing a growing burden of dementia and neurological conditions worldwide. By adopting healthy behaviors and addressing modifiable risk factors, individuals can improve their cognitive function and reduce the risk of age-related decline.
A new American Heart Association scientific statement highlights disparities in risk factors, symptoms, screening, treatment, and outcomes for women with peripheral vascular disease. The statement emphasizes the need for tailored prevention and treatment strategies to improve health equity.
The European Centre for Disease Prevention and Control reports a significant increase in measles cases across EU/EEA countries, with eight out of ten unvaccinated individuals contracting the disease. Vaccination levels fall short of the 95% target, leaving vulnerable populations susceptible to measles.
A new study analyzing global data from 1990 to 2021 found significant cross-country disparities in Alzheimer's disease and other dementias, with approximately two-thirds of individuals living in low- and middle-income countries. The study highlights the need for targeted prevention and control strategies in different countries.
Researchers have discovered how cholesterol crystals form in human bodies, shedding light on heart disease and gallstones. The team identified a special solvent that mimics the body's natural environment, allowing them to watch how cholesterol crystals grow in real time.
A new study from Tel Aviv University used AI tools to discover that 23.9% of people exercise to improve their appearance, while 18.9% prioritize physical health and 16.9% for mental well-being. The study also identified effective strategies for maintaining physical fitness, including creating exercise habits.
A University of Illinois Chicago study reveals that intranasal herpes infection can cause severe neurobehavioral symptoms, including anxiety and cognitive issues. The research suggests that the virus exploits a cellular enzyme to produce behavioral symptoms, emphasizing the need for prevention and treatment.
The American College of Physicians updates its guidelines recommending SGLT2 inhibitors for chronic kidney disease (CKD) management, regardless of diabetes type. The new guidelines emphasize the importance of tailored care and suggest individualized risk-based approaches to predict kidney failure.
A study of nearly 2,500 postmenopausal women found that taking more daily steps and engaging in moderate-to-vigorous physical activity were associated with a significantly reduced risk of death from cardiovascular disease. Even walking fewer than 5,000 steps per day showed a risk reduction.
Research presented at the American Heart Association's 2025 Scientific Sessions found a link between insomnia, poor sleep duration, and elevated blood pressure in teenagers. The study suggests that addressing sleep health is crucial for heart health in adolescents.
A new study has discovered how antibodies help protect against Strep A infections and is contributing to the development of a Strep A vaccine. The research used the world's only human challenge model for Strep A, which uncovered the power and potential for this model to accelerate vaccine development.
A new study analyzing health records from 2012 to 2022 found significant differences in cardiovascular disease risk factors among Asian American, Native Hawaiian, and Pacific Islander populations. The research suggests that regular monitoring of risk factors may help prevent cardiovascular disease among these groups.
The study highlights the significant protective role of Asah1 in preventing NAFLD progression by regulating hepatic lipid homeostasis and cellular maintenance processes. The findings suggest that targeting Asah1 expression or activity may inform new therapeutic strategies for improving patient outcomes.
Research suggests that higher levels of essential minerals such as copper, manganese, and vitamin B12 during pregnancy may reduce the risk of developing high blood pressure in middle age. The study analyzed data from over 500 women and found a significant association between these mineral levels and lower blood pressure risk.
The study emphasizes the importance of awareness in preventing Rocky Mountain spotted fever. Veterinarians and doctors must learn to recognize symptoms, understand treatments, and prescribe antibiotics like doxycycline to prevent death and severe illness.
A large-scale Korea University study investigates the link between early menopause and type 2 diabetes risk among postmenopausal women in South Korea. The research reveals that premature menopause is associated with a higher risk of developing type 2 diabetes, emphasizing the critical role of hormonal changes in metabolic health.
A new study published in the European Journal of Preventive Cardiology found that a type of diabetes medication called SGLT2 inhibitors can significantly lower the risk of heart failure and hospital visits related to heart failure in cancer patients. The benefits were particularly promising for breast cancer patients receiving anthracy...
A risk prediction model was developed to identify patients unlikely to complete HPV vaccination. The model uses patient demographics and clinical characteristics to guide targeted interventions, increasing vaccination rates among high-risk groups.
The study found that combining coronary calcium score with a primary prevention strategy in intermediate-risk patients with a family history of coronary artery disease reduces atherogenic lipids and slows plaque progression compared to usual care. This data supports the use of CAC scores to assist intensive preventive strategies.
A polypill programme combining a statin and three blood pressure lowering drugs could prevent thousands of heart attacks and strokes annually. The approach would be a flagship strategy for disease prevention rather than treatment.
A new AI prediction model, UNAFIED, uses machine learning to predict whether a patient has or might develop detectable AFib within two years. The non-invasive approach provides a practical option for proactive screening of patients at elevated risk for AFib.
A survey reveals that most people are unaware of HPV's impact on cancer risk and its spread. The human papillomavirus (HPV) is more common among men than women, and the virus is associated with rising rates of oropharyngeal cancers, which can take years to develop after initial infection.
PARP inhibitors have been found to be effective in treating cancers with BRCA1/2 mutations by blocking DNA repair pathways. The combination of PARPis with chemotherapeutic drugs can also improve treatment efficacy, increasing DNA damage and blocking repair processes.
Researchers are enrolling volunteers for a four-year study that will use advanced imaging, genetics, exercise science, neuroscience, and remote monitoring to investigate age-related health decline. The goal is to help individuals and healthcare practitioners better prevent the impact of disease on older adults.
A third of children and adolescents will be overweight or obese within the next 25 years, according to a new study. The global obesity rate for those between 5-24 years old tripled from 1990 to 2021, rising by 244 per cent to 174 million.
The collaboration aims to close gaps in early recognition and management of IPF by equipping healthcare providers, public health professionals, and patients with necessary resources. The organizations will employ designated activities to build a knowledge base, develop survey tools, and create educational and awareness assets.
Scientists have identified a new target to prevent cold sores by understanding how the herpes virus triggers its own immune response. The discovery has important implications for genital herpes caused by the same virus, with potential treatments in development.
CerTracker LLC, a digital credential management platform, aims to streamline compliance and onboarding for healthcare professionals. The company will use the $10,000 grant to reduce administrative burdens and improve workforce efficiency in healthcare settings.
The Global Pediatric Pulmonary Alliance recommends prophylactic mAbs as the best available preventive measure against RSV. A single dose of long-acting mAbs can provide season-long protection to infants, with real-world evidence supporting this strategy.
The influenza vaccine provided moderate protection against influenza A strains, but strong protection against influenza B. The vaccine was most effective in preventing severe disease among children and adolescents, with a high effectiveness rate.
Surgical adhesions form after surgery, causing severe complications like bowel obstructions, chronic pain, and infertility. A new report explores solutions to this widespread problem, including the development of standardized tools and innovative treatments.
The University of Cambridge has launched an Engineered Pandemics Risk Management Programme to address the urgent challenge of managing future engineered pandemics. The programme aims to build a network of experts from academia, government, and industry to understand social and biological factors that drive engineered pandemic risks.