The influenza vaccine provided moderate protection against influenza A strains, but strong protection against influenza B. The vaccine was most effective in preventing severe disease among children and adolescents, with a high effectiveness rate.
This study utilized deep learning models to diagnose and predict the likelihood of malignant transformation in oral potentially malignant disorders. AI-driven approaches offer noninvasive, cost-effective, and objective means to enhance early detection and improve patient outcomes.
Researchers have developed an online exercise program that improves posture, balance, and strength in older adults, reducing fall risk by up to 36% in some cases. The 'Strong Foundations' program uses semi-individualized instruction to correct exercise form and provide personalized guidance.
Colorectal cancer is a leading cause of mortality in China due to late-stage diagnosis. Emerging non-invasive diagnostic tests, innovative imaging techniques, and AI applications enhance CRC detection and diagnosis. However, expanding accessibility and promoting public awareness remain key challenges.
A new study published in The Lancet Digital Health found that accelerated ageing in specific organs can predict diseases across the entire body. Organ ageing rates were linked to increased risks of various diseases, including cardiovascular disease, respiratory infections, and dementia.
A new University of Cincinnati trial is comparing two types of omega-3 supplements, LPC-DHA and TAG-DHA, to slow or prevent dementia progression in elderly adults. Researchers aim to investigate whether LPC-DHA supplementation increases CSF DHA levels and improves cognitive function.
A study by Barcelona Institute for Global Health estimates that increasing green spaces in the city could prevent 178 premature deaths per year. The proposed Green Corridors plan would lead to a 3.64% increase in green space, reducing mortality rates and heat-related deaths.
A recent study from the University of Missouri and Yale University found that restricting flavored e-cigarettes leads to a decrease in vaping among young adults. However, this restriction also increases traditional cigarette smoking among young adults compared to states without such restrictions.
Only about 1 in 5 older Americans have undergone cognitive screening in the past year, highlighting a persistent barrier to diagnosis and treatment. Researchers emphasize the importance of early conversations about cognitive health to prevent progression and improve outcomes.
The Childhood Obesity Prevention, Evaluation and Treatment Toolkit provides healthcare providers with practical guidance for preventing, evaluating, and treating childhood obesity. The toolkit is grounded in scientific evidence and offers actionable treatment approaches for children and adolescents dealing with overweight and obesity.
The University of Texas MD Anderson Cancer Center received nearly $23 million in CPRIT funding to advance cancer research, translational science, and clinical trials. The funding will support the recruitment of a first-time tenure-track faculty member and enhance the understanding of cancer biology.
A new study from the University of Texas at Arlington found that Americans aged 65 and older who experienced parental divorce as children were more likely to suffer a stroke compared to their peers. The study analyzed data from over 13,000 older Americans and found that about 14% had experienced parental divorce during childhood.
A new study highlights the importance of distinguishing between domains of physical activity. Researchers found that engaging in moderate to vigorous physical activity during leisure time reduces the risk of type 2 diabetes, while occupational physical activity has no similar benefits. The study's findings suggest that current WHO phys...
SourceElsevier·JournalAmerican Journal of Preventive Medicine·TypeData/statistical analysis·DateFeb 18, 2025
Researchers have discovered a critical link between a cholesterol byproduct and Parkinson's disease development in mice. The study highlights the role of 24-OHC in forming Lewy bodies and killing dopamine neurons, with potential therapeutic targets emerging as drugs that prevent its production.
ABT-263 eliminates harmful aging cells in the gut, reducing inflammation and lowering cancer risk in a mouse model of GI cancer. The study suggests that removing senescent cells could help prevent radiation-related GI cancer, highlighting the potential of senolytic drugs as a preventive treatment.
The American Heart Association has chosen five US regions to implement a new preventive health initiative aimed at improving care for people with cardiovascular-kidney-metabolic (CKM) syndrome. The initiative will increase awareness and screening for CKM syndrome and facilitate collaboration among healthcare professionals.
Researchers at University of Gothenburg have identified a critical mechanism to slow down Crohn's disease progression by repairing the protective barrier of the gut. By reinforcing the gut's natural defenses, new drug targets may be developed to treat the disease.
A cross-sectional study found that perceived stress, inadequate social support, racial discrimination, and neighborhood deprivation negatively impacted systemic and tumor immunity in Black women. These findings may inform prevention and public health interventions for cancer health disparities.
A new global guideline has been published to manage fungal infections caused by Candida, affecting millions worldwide annually. The guideline establishes standards for prevention, diagnosis, and innovative treatment approaches.
Researchers have discovered Mitofusin 2's unexpected function in maintaining protein quality within cells, interacting with the proteasome and chaperones to prevent toxic aggregates. This novel connection has far-reaching implications for treating CMT and other neurodegenerative diseases.
A new review study found significant gaps in existing research on breast cancer within the Black community and barriers preventing eligible but non-participating women from screenings. The study highlights the need for culturally sensitive research to address emotional and psycho-social barriers faced by Black women.
Researchers identified 14 proteins and 2 metabolites associated with prediabetes progression to diabetes, including DCXR and GSTA3. Inflammation and immune system pathways also play a key role in glucose homeostasis.
A study at Lund University found that brain trauma triggers Alzheimer's disease through vascular changes, challenging existing paradigms. The research team identified increased aggregation of amyloid-beta and vascular alterations in patients with traumatic brain injury.
A large study found that telemedicine and training apps had minimal positive effects on patients with type 2 diabetes and coronary heart disease. The study suggests that direct care from medical professionals remains crucial for improving health outcomes in this population.
The study reveals that certain DNA regions are more prone to damage but also better repaired by cells. Transcription factors can either help or harm DNA, highlighting the importance of efficient repair in determining mutation formation.
A new study published in the American Heart Association's Hypertension Journal highlights distinct blood pressure patterns among East and South Asian adults living in the UK. Researchers found that South Asian adults face high blood pressure-related heart risks earlier in life, while East Asian adults see risks rise in later years.
A new study from NUS Medicine has found that the protein Spns1 plays a key role in recycling fats out of cell compartments called lysosomes, preventing diseases like lysosomal storage disorders. The research uses cryoelectron microscopy to understand how Spns1 transports fats and highlights its importance for cellular health.
A new review paper published in Addiction found 'very low-certainty evidence' to support the claim that nicotine vaping causes young people to start smoking. However, the study also suggests that vaping may contribute to declines in youth smoking rates, particularly in the US.
The new center aims to advance understanding, prevention, and management of sepsis through innovative research. Dr. Chanu Rhee and Dr. Michael Klompas will lead the effort, building on their expertise in sepsis surveillance, prevention, treatment, and policy.
Researchers identified a link between Alzheimer's disease, cell function, and cholesterol in the brain. Lowering oxysterol levels freed trapped ABCA1, restoring its healthy state, and showed potential as a new treatment approach.
A new study suggests that self-collected test kits could increase reproductive health access among youth due to their convenience, privacy, and comfort. The findings highlight the need to prioritize STI testing among young people to address disparities in health care access.
Researchers developed a 3D microscopic version of the human intestines on a chip, allowing for real-time examination of gut microbes' interactions with the human intestine. The 'Gut-Microbiome on a chip' model enables the study of complex interplay between gut microbes and health, facilitating targeted microbiome-based interventions.
The American Heart Association reports that Black communities face disproportionately higher risk of heart disease, stroke, and hypertension, leading to poorer survival outcomes. Hands-Only CPR training and heart health education are critical to addressing these disparities and advancing equitable health solutions.
A new study from Karolinska Institutet found that women with complicated pregnancies and their sisters are at higher risk of cardiovascular disease. Genes and shared environmental factors may contribute to this association.
A recent study explores the connection between chronic inflammation and arrhythmia development, identifying potential therapeutic targets for preventing and treating AF. The research team discovered that interleukin-1 beta (IL-1β) triggers atrial fibrillation by activating its receptors on macrophages.
Researchers studied whether transcranial direct current stimulation could enhance constraint-induced movement therapy for post-stroke motor recovery. The study found no significant improvement in motor skills, despite using three doses of electrical stimulation on 129 stroke survivors. Future trials aim to address limitations and impro...
A new biodegradable polymer-based delivery system efficiently transports mRNA, outperforming existing lipid nanoparticles in delivery efficiency and expression duration. The study also shows improved immune response results without liver accumulation or toxicity.
A new study from Penn State finds that oral tissue samples significantly affect epigenetic clock accuracy, leading to older age estimates. Researchers tested five tissue types and seven epigenetic clocks, concluding that blood-based samples are more accurate in measuring biological age.
Two comprehensive datasets from the Gabriella Miller Kids First Pediatric Research Program explore childhood cancers and congenital disorders. The new datasets aim to identify genetic causes and links between these diseases in children, ultimately supporting the development of improved treatments.
Eleven scientists will be recognized for their individual exceptional professional achievements and contributions to stroke care and research. Four groundbreaking scientists are devoted to stroke research, while six others will be recognized for their new research findings presented during the meeting.
The Primary Prevention Trial aims to determine whether stopping early molecular changes can prevent Alzheimer's disease from taking hold. The study will enroll people as young as 18 with few or no detectable Alzheimer's-related molecular changes in their brains.
The National Comprehensive Cancer Network is joining the global effort to improve awareness and knowledge of cancer risks through its 'United by Unique' campaign. Patient advocates from NCCN guidelines panels are sharing their personal stories to highlight the importance of a people-centered approach in cancer care, which recognizes ev...
A global study published in JACC found that secondary prevention medications for cardiovascular diseases are underused worldwide, with little improvement over time. Medication use varied by country income level, with lower rates in low-income countries.
A new pilot study assesses how caregivers use advanced wearable technology to support people with dementia, finding that it reduces emotional strain and increases caregiver satisfaction. The technology, called Theora Care, provides a wearable device and smartphone application that alerts caregivers when the person has wandered.
A new study by UC San Francisco found a marked increase in advanced prostate cancer rates across California since doctors stopped routine screening, with death rates plateauing in most regions. The study emphasizes the need for screening that can identify fatal tumors without raising false alarms.
Researchers found that women who had used the oral contraceptive pill had a lower risk of ovarian cancer, with a 39% reduced risk for those who had given birth to two or more children. The study also identified certain biomarkers and lifestyle factors associated with a lower risk of ovarian cancer, including lower body weight and short...
Researchers at Lancaster University have developed a new method to detect Alzheimer's disease by analyzing changes in brain oxygenation dynamics and neuronal function. The study found that individuals with Alzheimer's disease exhibit altered respiratory frequency, which may be an early indicator of the condition.
The American Heart Association teamed up with 20 influential creators to launch American Heart Month and raise awareness about heart health. The event empowered audiences with knowledge about prevention while encouraging donations to support the Association's lifesaving mission.
A new study found that propranolol, commonly used to treat high blood pressure and prevent migraines, can reduce the risk of ischemic stroke in women with migraines. The medication was particularly effective in reducing stroke risk for women without aura, but not men.
A recent study found that Streptococcus anginosis, a common mouth bacteria, is abundant in the guts of people with acute stroke and linked to a worse prognosis. The researchers also discovered that levels of this bacteria were associated with increased mortality rates two years after stroke.
A new research project funded by a $600,000 grant is exploring the mechanics behind episiotomies, with the goal of developing safer and more effective surgical practices. The study uses advanced experimental techniques and computational simulations to understand how incisions spread and potentially lead to tears.
A preliminary study found that regular dental flossing may lower the risk of stroke caused by blood clots and irregular heartbeats. The study, which followed over 6,000 participants for 25 years, found a significant reduction in irregular heartbeats among those who flossed regularly.
A study found that F.A.S.T. acronym was equally effective as BE-FAST in prompting people to call 911 at the first sign of stroke. However, the key stroke warning signs were remembered better with the F.A.S.T. acronym.
A recent study found that patients who left emergency departments before being medically advised had higher rates of readmission, mortality, and increased costs. The COVID-19 pandemic led to a 53.6% increase in such cases, primarily due to concerns about infection, long wait times, and dissatisfaction with care.
Researchers have identified ALPK2 as a potential therapeutic target for treating heart failure with preserved ejection function (HFpEF). The enzyme is believed to prevent stiff heart conditions through regulating the TPM1 gene. This discovery offers new hope for developing treatment options targeting ALPK2.
Research from RIKEN Center for Integrative Medical Sciences found that infant gut bacteria are associated with food sensitivities and allergies, particularly to eggs. The study suggests that probiotic supplements, such as Bifidobacterium, may help prevent food allergies in at-risk infants.
A broadly neutralizing antibody has been shown to protect monkeys against severe H5N1 avian flu disease. The antibody's stable structure ensures it can withstand virus variants, providing universal protection against a globally spreading airborne infection. Serum levels of the antibody remained stable for up to 12 weeks.
A new meta-analysis of over 249 studies and 251,713 US teens finds that knowledge about safer sex is not enough to promote condom use. The study highlights the importance of confidence, planning, and effective communication with partners in encouraging condom use among teens.
Researchers from Osaka University found that Japan's state of emergency declarations led to increased hygienic behaviors and risk perception, which persisted even after the policy was lifted. However, older people became less fearful of COVID-19 and were less likely to wear masks.
A new survey finds that nearly three-quarters of US adults support requiring children to be vaccinated against preventable diseases, while over half support prohibiting unvaccinated children from attending school. However, support for this prohibition has dropped significantly since the Covid-19 pandemic, and there is growing support f...