Chronic stable angina affects approximately 10 million Americans, primarily older adults and women. Common comorbidities like diabetes are associated with poorer outcomes in this subgroup. The study highlights the growing prevalence of recurring ischemia, its socioeconomic burden, and therapeutic targets for management.
This special issue of Cardiovascular Innovations and Applications Journal covers key aspects of stable ischemic heart disease, including contemporary management strategies and epidemiology. The collection of reviews and commentary provides insights into the latest research and clinical practices for this condition.
A collection of 27 papers has been compiled to better understand the pathophysiology of endocrinopathic laminitis in horses. The research highlights the key role of insulin dysregulation and equine metabolic syndrome in driving the condition.
The bellygenes initiative is a large-scale genetic project studying the genetic makeup of 800,000 Europeans in relation to irritable bowel syndrome. The study aims to reveal pathophysiological pathways that can help explain IBS etiology and inform molecular reclassification of patients.
Researchers found that certain lipid mediators can delay the onset and progression of heart failure. The lack of standard drugs stimulating these mediators suggests a need for re-evaluation of current treatment protocols to improve disease outcomes.
Organs-on-chips reconstitute functional interfaces between living tissues, enabling complex organ-level functions and insights into human pathophysiology. Researchers use these devices to study communication in biology and develop personalized medicine.
Muscle wasting occurs rapidly in critically ill patients, with significant skeletal muscle weakness and physical disability persisting for at least 5 years. Early interventions to enhance anabolism may be required to limit or prevent muscle loss.
The International Osteoporosis Foundation provides guidance on screening strategies for osteoporosis in young adults, emphasizing the need for caution in diagnosis and treatment. The review highlights the importance of distinguishing between low bone mass and skeletal fragility in this age group.
Research highlights the critical role of food intolerance in IBS symptoms, particularly diarrhea, which alters epithelial function and increases intestinal permeability. The study provides valuable insights into the relationship between intestinal inflammation and increased permeability in IBS patients.
Artery Research is a quarterly journal published by Elsevier in collaboration with the Association for Research into Arterial Structure and Physiology (ARTERY). The journal features original articles, review articles, case studies, and more on advancements in arterial structure and physiology research.
Researchers found that delta-9-THC, the main active ingredient in cannabis, induced schizophrenia-like symptoms in some subjects. These symptoms included paranoia, thought disorder, and problems with memory and attention.