Articles tagged with Risk Factors
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
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Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study of 500,000 UK participants found insulin resistance associated with higher risk of 26 conditions, such as sleep disorders and pancreatitis, and lower risk of five diseases, including anaemia and Parkinson's disease. Insulin resistance also linked to increased mortality risk in women.
Research found that maintaining good cardiovascular health during the first trimester of pregnancy can partially mitigate the risk of adverse pregnancy outcomes. The study's results suggest that preconception and early pregnancy cardiovascular health counseling is crucial for preventing hypertensive disorders of pregnancy.
Research found a positive association between outdoor nighttime light pollution and Alzheimer's disease prevalence, particularly in those under 65. Higher light intensity was associated with greater AD prevalence in this age group, suggesting they may be more vulnerable to the effects of light exposure.
A comprehensive review of genetic and population studies challenges conventional wisdom about the relationship between genetic risk and cognitive deficits in schizophrenia. Premorbid cognitive impairment is largely explained by non-familial factors rather than inherited genetic variants.
A study published in JAMA finds that balloon angioplasty plus aggressive medical management reduces the risk of any stroke or death within 30 days. The treatment approach may be effective for symptomatic intracranial atherosclerotic stenosis, but with consideration for increased stroke risk after balloon angioplasty.
Two studies highlight elevated blood pressure prevalence among 8-19 year-olds in the US, with social determinants impacting health outcomes. Addressing these factors through targeted public health strategies is essential to improve outcomes and prevent long-term heart disease.
A recent study published in the Journal of Nutrition Education and Behavior examines the connection between food insecurity and gestational diabetes risk among young American Indian and Alaska Native females. The research highlights how targeted risk reduction methods could significantly improve diabetes health outcomes for this popula...
Non-Communicable Diseases (NCDs) are a major global health issue, characterized by their chronic nature and long-term impact on quality of life. In China, understanding the extent and distribution of NCDs is essential for developing effective public health strategies.
Researchers found that sustained neck exertions alter the cervical spine's curvature, leading to muscle fatigue and increased risk of neck pain. The study provides new insights into the mechanical changes that occur in the spine and muscles when performing repetitive tasks.
A study found that RSV vaccination significantly reduced hospitalization risk among adults 60+ in the US, offering protection against severe RSV disease. The vaccine demonstrated effectiveness in high-risk populations, including those over 75 and with immunocompromising conditions.
A large-scale prospective cohort study found a positive association between regular mobile phone use and incident cardiovascular disease risk, particularly in smokers and individuals with diabetes. Poor sleep patterns, psychological distress, and neuroticism may be key mechanisms underlying this association.
A study of bottled, tap, and household-treated water in the San Francisco Bay Area found potential health risks from trihalomethanes in all sampled sources. The researchers analyzed various types of drinking water, including samples collected directly from households, to determine their chemical compositions.
A new study by Mass General Brigham has found that obesity may be an important risk factor for infection from the virus that causes COVID-19. Individuals with obesity were 34% more likely to become COVID positive after reported exposure than those without obesity, indicating a possible link between obesity and increased transmission risk.
A cohort study found no association between GLP-1 receptor agonist use and increased risk of suicide death or related disorders in patients with type 2 diabetes. The study included mostly patients with type 2 diabetes.
A new systematic review and meta-analysis found a slight increase in ADHD risk and heightened vulnerability to cannabis consumption in children exposed to cannabis in utero. The study suggests caution when it comes to cannabis use during pregnancy, highlighting the need for continued research into long-term effects.
A new study from the University of Kansas reveals that individuals with pre-existing disabilities are more than twice as likely to develop long COVID. The research found that chronic illnesses and mental illness/psychiatric disabilities were the most common types of disabilities among those experiencing long COVID.
Researchers found an exponential relationship between HIV risk factors, demonstrating that having multiple risk factors is much worse than having only one. The study used data from a survey of LGBTQ+ youth and suggests that interventions addressing multiple risk factors can provide substantial benefits.
A first-of-its-kind study published in The Lancet Regional Health Americas found that gun-free zones have a preventive effect and do not attract active shooters. Researchers matched 150 places with shootings to 150 control places without shootings, finding that active shootings were 62.5% less likely to occur in gun-free establishments.
A post hoc analysis found semaglutide treatment did not increase the risk of developing depression or suicidal ideation and was associated with a small reduction in depressive symptoms. Monitoring for mental health concerns is essential for individuals with obesity to receive proper support and care.
Vultures, like young humans, explore new sites and socialize frequently when they're young. However, as they age from around 10 years old, they scale back on socializing and prefer to stay at the same roosting site, similar to humans who tend to stay home.
A nationwide study in Sweden reveals that short-term exposures to lower air temperature and cold spells are associated with an increased risk of myocardial infarction hospitalization after two-six days. Researchers found that this delay in hospitalizations suggests a delayed onset of cold-related impacts on MI risk.
A novel low-dose 3-in-1 blood pressure pill (GMRx2) significantly reduces blood pressure in patients with uncontrolled hypertension. After six months treatment, the GMRx2 group achieved a 5.8mmHg lower systolic blood pressure compared to standard care.
Researchers found that measuring two types of fat in the bloodstream along with C-reactive protein can predict a woman's risk for cardiovascular disease decades later. Women with high levels of LDL cholesterol, Lp(a) and CRP had increased associated risks for heart disease, stroke and coronary heart disease.
This study found modestly increased risks of inflammatory bowel disease and bullous skin disorders in hospitalized patients infected with the Omicron variant. Booster vaccination mitigated long-term autoimmune sequelae risk.
New studies show semaglutide reduces all-cause death, CV death, and non-CV death in people with overweight or obesity and established cardiovascular disease. The medication also improves heart failure symptoms and physical limitations in those with obesity-related HFpEF, regardless of sex.
Researchers in human nutrition developed an innovative tool to assign a healthy hydration recommendation score to governments, promoting water and discouraging sugary beverages. The study analyzed 93 countries with dietary guidelines, finding that 48 had complementary messages encouraging water and reducing sugary beverage intake.
Experts propose a series of scientific principles and experimental approaches to assess potential carcinogenicity of gene therapies. Data transparency is crucial, with publicly accessible data from viral integrations site studies and clinical settings.
Researchers used genetic method Mendelian randomization to show high levels of fasting insulin cause reduction in Lp(a), rather than the other way around. Low Lp(a) is unlikely to be a risk factor for type 2 diabetes, independent of pre-existing hyperinsulinaemia and insulin resistance.
High levels of lipoprotein (a) found in 20-34% of Polish patients with heart disease or at risk. Lp(a) measurements may be crucial in preventing cardiovascular diseases and atherosclerosis progression.
A study from University of Gothenburg links work-related pain to mental illness among construction workers. Managers' empathetic or neglectful attitudes are highlighted as key factors in mental health.
Researchers have made progress in understanding how genetics and lifestyle factors influence dementia risk through epigenetics. DNA methylation signatures in blood can mirror protein biomarker levels in spinal fluid samples, used for diagnosing dementia.
A North Carolina State University study found that only 12% of organizations providing residential opioid substance use services are licensed by the state. Only a quarter allow patients to access proven opioid agonist treatment (OAT), which has better outcomes and cuts overdose deaths in half.
After three decades, perioperative mortality rates for living kidney donors have decreased substantially, from fewer than 1 event per 10,000 donations in the past decade to even lower numbers. Donor demographics, such as male donors and those with a history of hypertension, are identified as high-risk groups.
The UofL Green Heart Louisville Project found that residents living in neighborhoods with more trees showed lower levels of general inflammation, a risk indicator for heart disease. The study showed a 13-20% reduction in inflammation, corresponding to a nearly 10-15% reduced risk of heart attacks and certain cancers.
A new NIH-funded study found minor changes in youth mental health overall, but significant variations depending on age, race, gender, and pre-existing mental health. Children with clinically significant problems before the pandemic improved, while others experienced declines or no change.
Heat-related mortality rates in the US rose between 1999 and 2023, reversing a previous trend. Climate change projections suggest continued increases, highlighting the need for access to hydration centers and cooling centers.
Researchers highlight the importance of screening for urinary symptoms in men, linking them to cardiometabolic disorders. The study recommends addressing these conditions to identify and treat underlying heart problems early, potentially reducing morbidity and mortality among men.
Researchers found that people with chronic diabetes complications are up to three times more likely to have a mental health condition, while those with mental health disorders are up to two and a half times more likely to experience sustained diabetes complications. The study highlights the importance of screening for both risk factors.
A cohort study found elevated depression and anxiety levels in unvaccinated people with COVID-19 diagnosis compared to before or without the virus. Vaccination was associated with lower incidence of mental illnesses after hospitalization for COVID-19.
A recent study published in JAMA Psychiatry found that children with persistently raised inflammation are at a higher risk of experiencing serious mental health disorders, including psychosis and depression, in early adulthood. The research also discovered that those who experienced inflammation at a young age were more likely to devel...
A large-scale study investigated the relationship between childhood obesity and immune-mediated skin diseases (IMSDs), such as atopic dermatitis and psoriasis. The study found that obese children were more likely to develop these conditions, with changes in body weight affecting their risk of developing these diseases.
A cross-sectional study found that approximately 50% of cancer survivors experience financial hardship, with social vulnerability playing a key role in increasing levels of hardship. Younger, Medicare or Medicaid beneficiaries, and those with advanced disease are particularly vulnerable to financial strain.
A new national study reveals significant regional variations in the likelihood of being diagnosed with Alzheimer's disease or another form of dementia. Despite controlling for demographic and population-level risk factors, the study found that differences in diagnostic intensity persist across regions.
A new study found that bone fracture rates in older women differ dramatically by race, with White women having the highest risk. Hispanic women had a lower risk of 10%, while Asian-American women experienced varying fracture rates depending on their ethnicity. The study highlights the need to better understand factors behind these diff...
A uterus transplant was successfully performed on women with absolute uterine-factor infertility, resulting in a high live birth rate. However, the procedure was also associated with significant medical and surgical risks for both recipients and donors.
A University of Gothenburg study found that work-related stress, particularly job conflicts and lack of influence, significantly increase the risk of future sick leave. Women who experienced these stressors were more than twice as likely to take sick leave, with adjusted factors indicating a significant impact on their wellbeing.
A study suggests that higher levels of UV radiation in areas with limited sunshine are associated with a drop in deaths due to cardiovascular disease and cancer. Sunbed use was also found to be linked to a reduced risk of these deaths, but further research is needed to confirm the findings.
A new Cleveland Clinic study reveals that diet-derived molecules called metabolites are the main drivers of young-onset colorectal cancer risk, particularly those associated with red and processed meat. The research suggests that addressing diet with doctors can help prevent colon cancer in younger adults.
A cohort study found that PTSD is a modifiable risk factor for a modest reduction in microvascular complications in veterans with comorbid PTSD and type 2 diabetes. The study suggests further research is needed to confirm findings in non-Veterans Health Administration settings.
A UK cohort study reveals that even low-risk alcohol consumption is linked to increased mortality among older adults with health-related or socioeconomic risk factors. The findings suggest that healthier lifestyles may play a role in the observed attenuation of mortality for wine drinkers and those who drink only during meals.
A global study predicts significant increases in cancer cases and deaths among men between 2022 and 2050, with widening disparities by age and country's economic status. Disparities are projected to worsen, with poorer survival rates observed among older men and those living in low-human development index countries.
A recent study analyzing over 1.5 million patients' electronic health records found that mild cognitive impairment (MCI) is significantly underdiagnosed in rural areas of West Michigan. Researchers discovered a higher rate of MCI skippers, where patients progress directly to dementia without a prior diagnosis, in these communities.
A new heart MRI technique accurately estimates pressures inside the heart to predict heart failure risk in a general population. Key risk factors identified include age over 70, high blood pressure, obesity, alcohol consumption, and male gender.
A cohort study found an association between cannabis-related disorder and the development of head and neck cancer. The study highlights the need for further research on the mechanism of this association and dose response to support evidence of cannabis use as a risk factor.
Commonly prescribed oral antibiotics increase risk of serious cutaneous adverse drug reactions compared to macrolides. Sulfonamides and cephalosporins carry the highest risk, prompting prescribers to opt for lower-risk alternatives when clinically appropriate.
Discrepancies in e-cigarette products containing nicotine analogues may lead to uncertainty about user exposure, hindering risk assessment for clinical and regulatory purposes. The largely unknown acute and chronic inhalation hazards and addictive potential of nicotine analogues pose a significant concern.
A University of Michigan-led study found that higher levels of metals in blood and urine are associated with a greater risk for ALS and shorter survival. Occupational exposure to metals was also linked to increased metal levels, emphasizing the need for accounting for environmental factors when evaluating overall exposure risk.
Research published in the Journal of Nutrition Education and Behavior found that meals from community cafés had significantly higher diet quality than meals not eaten at the café, measured by the Healthy Eating Index. This improvement was particularly pronounced for individuals with very low food security. The study suggests that commu...
Maintaining stable hemoglobin A1c levels in individualized target ranges may lower Alzheimer disease and related dementias risk. Lower HbA1c time in range could identify patients at increased risk of these conditions.
Researchers have identified nearly 300 common and over 20 rare genetic variants as significant risk factors for schizophrenia. The study emphasizes the role of multiple genes rather than single-gene causation, revealing complexity in the mechanisms underlying the disorder.