Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
A cross-sectional study found that over 50% of adults with uncontrolled hypertension in the US are unaware of their condition and untreated. Despite treatment, 70.8% of patients experience persistent uncontrolled hypertension, highlighting a need for improved healthcare strategies to address this critical public health issue.
A new study published in Health Data Science reveals that both spontaneous and induced abortions are associated with an increased risk of premature mortality. The research found that induced abortions were strongly linked to cardiovascular death, while spontaneous abortions also elevated the risk of all-cause premature mortality.
A large-scale population analysis confirms tirzepatide's similar gastrointestinal tolerability to other GLP-1 medications without increased risk of diabetic retinopathy, medullary thyroid cancer, or pancreatitis. Researchers analyzed real-world evidence from the FDA adverse event reporting system database and found that tirzepatide has...
A recent study published in JACC: Clinical Electrophysiology found that quitting smoking can significantly lower the risk of atrial fibrillation, with former smokers having around 13% lower risk and current quitters having an 18% lower risk. The benefits of quitting are seen shortly after stopping smoking.
The study found that semaglutide was effective in preventing heart attacks and other major adverse cardiovascular events as well as death in adults with impaired kidney function. The results showed a significant reduction in cardiovascular disease risk with semaglutide, even among those with poor kidney function.
This cross-sectional study examines the relationship between neighborhood opportunity and preterm birth rates, finding disproportionate exposure by race and ethnicity. The study suggests that addressing neighborhood opportunity may be a modifiable factor contributing to racial and ethnic inequities in preterm birth.
Researchers found that women exposed to higher levels of nitrogen dioxide and inhalable particulate matter during the second trimester face an almost fourfold increased risk of postpartum depression. The study also discovered a sustained effect of air pollution on symptoms of depression for up to three years after birth.
A new study estimates nearly 10.5 million U.S. adults have A-Fib, a three-fold increase from previous estimates. Early detection and treatment can reduce its adverse outcomes.
A new trial revealed that a lifestyle-intervention program failed to reduce cardiovascular risk factors in US South Asians, but showed promising improvements in health behaviors. The study underscores the need for culturally tailored interventions to address the unique health needs of this growing ethnic group.
A new study published in the journal JCI Insight found that male mice fed high-cholesterol diets have increased cardiovascular disease risk in their female offspring. The researchers used a novel method to study sperm small RNA and discovered altered molecules that affect gene expression in early embryonic stem cells.
A new study finds that excessive social media use is associated with a higher risk of eating disorder symptoms in 9-14-year-olds, including binge eating and distress over weight gain. Problematic screen use may contribute to unhealthy behaviors and addictive tendencies.
A new preclinical blood test identifies adults most likely to develop severe respiratory conditions, including chronic obstructive pulmonary disease (COPD), by analyzing 32 proteins that accurately predict lung health data. The risk score indicates a high likelihood of hospital care, COPD development, and respiratory disease death.
A new study found that rural regions in Ontario have significantly higher rates of eating disorders among adolescents and young adults. The researchers suggest that stigma and socio-cultural dynamics may contribute to these disparities, highlighting the need for targeted interventions such as telehealth services.
A $15 million gift from Sally Ross Soter will support the Go Red for Women Venture Fund, investing in health companies targeting cardiovascular, metabolic, and neurologic solutions for women. The fund aims to close the gap in women's health investment and translate research into better patient care.
Researchers at UCSF identified signals in the metabolic system of infants who died from Sudden Infant Death Syndrome (SIDS), finding associations between lower C-3 levels and elevated C-14OH. Elevated biomarkers also led to reduced risk of SIDS, but further research is needed to validate these findings.
A case-control study found an association between abnormal birth metabolic analytes and sudden infant death syndrome, suggesting potential early risk identification. The study's findings could inform future research and clinical efforts focused on monitoring and preventing SIDS.
Research links impaired circadian heart rate fluctuations to microvascular disease and increased long-term risk of cardiovascular mortality in people with diabetes. Disrupted daily heart rate variations are associated with a doubled risk of dying from cardiovascular causes.
A new study found that skin cancer incidence in young adults declined in Sweden around 2015. The decrease in incidence and mortality is attributed to increased awareness of sun protection, reduced access to sunbeds, and changes in lifestyle habits such as spending more time indoors. The study suggests that continued emphasis on sun pro...
Research suggests that eating fruit, oats, and rye in childhood increases the risk of developing type 1 diabetes, but consuming berries may lower this risk. The study followed thousands of children in Finland from birth to age six and found associations between specific foods and an increased or decreased risk of islet autoimmunity.
A study of 500,000 UK participants found insulin resistance associated with higher risk of 26 conditions, such as sleep disorders and pancreatitis, and lower risk of five diseases, including anaemia and Parkinson's disease. Insulin resistance also linked to increased mortality risk in women.
Research found that maintaining good cardiovascular health during the first trimester of pregnancy can partially mitigate the risk of adverse pregnancy outcomes. The study's results suggest that preconception and early pregnancy cardiovascular health counseling is crucial for preventing hypertensive disorders of pregnancy.
Research found a positive association between outdoor nighttime light pollution and Alzheimer's disease prevalence, particularly in those under 65. Higher light intensity was associated with greater AD prevalence in this age group, suggesting they may be more vulnerable to the effects of light exposure.
A comprehensive review of genetic and population studies challenges conventional wisdom about the relationship between genetic risk and cognitive deficits in schizophrenia. Premorbid cognitive impairment is largely explained by non-familial factors rather than inherited genetic variants.
A study published in JAMA finds that balloon angioplasty plus aggressive medical management reduces the risk of any stroke or death within 30 days. The treatment approach may be effective for symptomatic intracranial atherosclerotic stenosis, but with consideration for increased stroke risk after balloon angioplasty.
Two studies highlight elevated blood pressure prevalence among 8-19 year-olds in the US, with social determinants impacting health outcomes. Addressing these factors through targeted public health strategies is essential to improve outcomes and prevent long-term heart disease.
A recent study published in the Journal of Nutrition Education and Behavior examines the connection between food insecurity and gestational diabetes risk among young American Indian and Alaska Native females. The research highlights how targeted risk reduction methods could significantly improve diabetes health outcomes for this popula...
Non-Communicable Diseases (NCDs) are a major global health issue, characterized by their chronic nature and long-term impact on quality of life. In China, understanding the extent and distribution of NCDs is essential for developing effective public health strategies.
Researchers found that sustained neck exertions alter the cervical spine's curvature, leading to muscle fatigue and increased risk of neck pain. The study provides new insights into the mechanical changes that occur in the spine and muscles when performing repetitive tasks.
A study found that RSV vaccination significantly reduced hospitalization risk among adults 60+ in the US, offering protection against severe RSV disease. The vaccine demonstrated effectiveness in high-risk populations, including those over 75 and with immunocompromising conditions.
A large-scale prospective cohort study found a positive association between regular mobile phone use and incident cardiovascular disease risk, particularly in smokers and individuals with diabetes. Poor sleep patterns, psychological distress, and neuroticism may be key mechanisms underlying this association.
A study of bottled, tap, and household-treated water in the San Francisco Bay Area found potential health risks from trihalomethanes in all sampled sources. The researchers analyzed various types of drinking water, including samples collected directly from households, to determine their chemical compositions.
A new study by Mass General Brigham has found that obesity may be an important risk factor for infection from the virus that causes COVID-19. Individuals with obesity were 34% more likely to become COVID positive after reported exposure than those without obesity, indicating a possible link between obesity and increased transmission risk.
A cohort study found no association between GLP-1 receptor agonist use and increased risk of suicide death or related disorders in patients with type 2 diabetes. The study included mostly patients with type 2 diabetes.
A new systematic review and meta-analysis found a slight increase in ADHD risk and heightened vulnerability to cannabis consumption in children exposed to cannabis in utero. The study suggests caution when it comes to cannabis use during pregnancy, highlighting the need for continued research into long-term effects.
A new study from the University of Kansas reveals that individuals with pre-existing disabilities are more than twice as likely to develop long COVID. The research found that chronic illnesses and mental illness/psychiatric disabilities were the most common types of disabilities among those experiencing long COVID.
Researchers found an exponential relationship between HIV risk factors, demonstrating that having multiple risk factors is much worse than having only one. The study used data from a survey of LGBTQ+ youth and suggests that interventions addressing multiple risk factors can provide substantial benefits.
A first-of-its-kind study published in The Lancet Regional Health Americas found that gun-free zones have a preventive effect and do not attract active shooters. Researchers matched 150 places with shootings to 150 control places without shootings, finding that active shootings were 62.5% less likely to occur in gun-free establishments.
A post hoc analysis found semaglutide treatment did not increase the risk of developing depression or suicidal ideation and was associated with a small reduction in depressive symptoms. Monitoring for mental health concerns is essential for individuals with obesity to receive proper support and care.
Vultures, like young humans, explore new sites and socialize frequently when they're young. However, as they age from around 10 years old, they scale back on socializing and prefer to stay at the same roosting site, similar to humans who tend to stay home.
A nationwide study in Sweden reveals that short-term exposures to lower air temperature and cold spells are associated with an increased risk of myocardial infarction hospitalization after two-six days. Researchers found that this delay in hospitalizations suggests a delayed onset of cold-related impacts on MI risk.
A novel low-dose 3-in-1 blood pressure pill (GMRx2) significantly reduces blood pressure in patients with uncontrolled hypertension. After six months treatment, the GMRx2 group achieved a 5.8mmHg lower systolic blood pressure compared to standard care.
Researchers found that measuring two types of fat in the bloodstream along with C-reactive protein can predict a woman's risk for cardiovascular disease decades later. Women with high levels of LDL cholesterol, Lp(a) and CRP had increased associated risks for heart disease, stroke and coronary heart disease.
This study found modestly increased risks of inflammatory bowel disease and bullous skin disorders in hospitalized patients infected with the Omicron variant. Booster vaccination mitigated long-term autoimmune sequelae risk.
New studies show semaglutide reduces all-cause death, CV death, and non-CV death in people with overweight or obesity and established cardiovascular disease. The medication also improves heart failure symptoms and physical limitations in those with obesity-related HFpEF, regardless of sex.
Researchers in human nutrition developed an innovative tool to assign a healthy hydration recommendation score to governments, promoting water and discouraging sugary beverages. The study analyzed 93 countries with dietary guidelines, finding that 48 had complementary messages encouraging water and reducing sugary beverage intake.
Experts propose a series of scientific principles and experimental approaches to assess potential carcinogenicity of gene therapies. Data transparency is crucial, with publicly accessible data from viral integrations site studies and clinical settings.
Researchers used genetic method Mendelian randomization to show high levels of fasting insulin cause reduction in Lp(a), rather than the other way around. Low Lp(a) is unlikely to be a risk factor for type 2 diabetes, independent of pre-existing hyperinsulinaemia and insulin resistance.
High levels of lipoprotein (a) found in 20-34% of Polish patients with heart disease or at risk. Lp(a) measurements may be crucial in preventing cardiovascular diseases and atherosclerosis progression.
A study from University of Gothenburg links work-related pain to mental illness among construction workers. Managers' empathetic or neglectful attitudes are highlighted as key factors in mental health.
Researchers have made progress in understanding how genetics and lifestyle factors influence dementia risk through epigenetics. DNA methylation signatures in blood can mirror protein biomarker levels in spinal fluid samples, used for diagnosing dementia.
A North Carolina State University study found that only 12% of organizations providing residential opioid substance use services are licensed by the state. Only a quarter allow patients to access proven opioid agonist treatment (OAT), which has better outcomes and cuts overdose deaths in half.
After three decades, perioperative mortality rates for living kidney donors have decreased substantially, from fewer than 1 event per 10,000 donations in the past decade to even lower numbers. Donor demographics, such as male donors and those with a history of hypertension, are identified as high-risk groups.
The UofL Green Heart Louisville Project found that residents living in neighborhoods with more trees showed lower levels of general inflammation, a risk indicator for heart disease. The study showed a 13-20% reduction in inflammation, corresponding to a nearly 10-15% reduced risk of heart attacks and certain cancers.
A new NIH-funded study found minor changes in youth mental health overall, but significant variations depending on age, race, gender, and pre-existing mental health. Children with clinically significant problems before the pandemic improved, while others experienced declines or no change.
Heat-related mortality rates in the US rose between 1999 and 2023, reversing a previous trend. Climate change projections suggest continued increases, highlighting the need for access to hydration centers and cooling centers.
Researchers highlight the importance of screening for urinary symptoms in men, linking them to cardiometabolic disorders. The study recommends addressing these conditions to identify and treat underlying heart problems early, potentially reducing morbidity and mortality among men.
Researchers found that people with chronic diabetes complications are up to three times more likely to have a mental health condition, while those with mental health disorders are up to two and a half times more likely to experience sustained diabetes complications. The study highlights the importance of screening for both risk factors.
A cohort study found elevated depression and anxiety levels in unvaccinated people with COVID-19 diagnosis compared to before or without the virus. Vaccination was associated with lower incidence of mental illnesses after hospitalization for COVID-19.
A recent study published in JAMA Psychiatry found that children with persistently raised inflammation are at a higher risk of experiencing serious mental health disorders, including psychosis and depression, in early adulthood. The research also discovered that those who experienced inflammation at a young age were more likely to devel...
A large-scale study investigated the relationship between childhood obesity and immune-mediated skin diseases (IMSDs), such as atopic dermatitis and psoriasis. The study found that obese children were more likely to develop these conditions, with changes in body weight affecting their risk of developing these diseases.