Articles tagged with Risk Factors
Researchers have identified nearly 300 common and over 20 rare genetic variants as significant risk factors for schizophrenia. The study emphasizes the role of multiple genes rather than single-gene causation, revealing complexity in the mechanisms underlying the disorder.
A cohort study found that aspirin use was associated with a greater absolute reduction in risk of colorectal cancer among individuals with less healthy lifestyles. Lifestyle risk factors may help identify those with a more favorable risk-benefit profile for cancer prevention with aspirin.
A new study suggests that public health interventions, such as reformulating food products and introducing low emission zones, could yield significant cost savings and QALY gains in England. The interventions studied could save up to £4bn by reducing dementia rates and helping people live longer and healthier.
A recent survey study found increased self-managed abortion attempts following federal abortion protection changes in the US. The study revealed that marginalized groups predominantly used ineffective methods, highlighting the need for expanded access to safe and effective abortion care.
A recent study found that mental health disparities in Los Angeles County worsened during the COVID-19 pandemic, particularly among non-white residents. The risk of depression grew more common in areas hit hardest by deaths from COVID-19, with stark divisions observed between white and non-white communities.
A new model developed by Penn State researchers more accurately predicts the causal relationship between genetic and environmental factors in disease development. The study found that lifestyle and environmental factors play a larger role than previously believed, offering new opportunities to mitigate disease risk.
Infants born to mothers with obesity are at higher risk of SUID due to a dose-dependent association between increasing maternal BMI and SUID risk. Research suggests that maternal obesity should be added to the list of known risk factors for SUID.
The PD GENEration study has found that 13% of participants have a genetic form of Parkinson's disease, significantly higher than previous estimates. The study, which reached its goal of 15,000 participants ahead of schedule, provides insights into the genetics of the disease and its potential for precision medicine.
A recent study published in ESC Heart Failure found that kidney dysfunction can be used as a criterion to stratify patients requiring implantable defibrillators. The research identified two key independent predictors for the risk of sudden cardiac death: left ventricular ejection fraction and estimated glomerular filtration rate.
Researchers studied Alzheimer disease blood biomarkers and found a strong association with incident all-cause dementia risk. Biomarker levels increased with age and were linked to dementia starting in midlife.
Women with bilateral mastectomy have a greatly diminished risk of contralateral breast cancer, yet experience similar mortality rates as patients treated with lumpectomy or unilateral mastectomy. The study highlights the importance of considering long-term risks and benefits in breast cancer treatment decisions.
A prospective cohort study found that both chronic and new anxiety were associated with a higher risk of developing dementia. The presence of chronic anxiety was linked to a 2.8-time higher risk, while new onset anxiety was associated with a 3.2-time higher risk.
A new study found that the incidence of hepatitis C virus (HCV) reinfection among men with HIV is 10-fold higher than primary infection rates in New York City. The researchers identified receiving semen in the rectum as the only risk factor for reinfection, contradicting previous assumptions about transmission routes.
A new University of Michigan study found that over 82% of Americans aged 50-80 take one or more prescription medications, with 80% open to stopping certain drugs. However, researchers stress the importance of personalized guidance for deprescribing older adults, particularly those taking medication for cardiovascular disease or diabetes.
A large population-based case-control study found a small increased risk of composite adverse outcomes with long-term oral corticosteroid use among individuals with atopic dermatitis. Health professionals must weigh benefits against potential risks, and monitor for adverse events.
Researchers found that anxiety disorders and depression significantly elevate the risk of incident DVT. Stress-related neural mechanisms may increase DVT risk through heightened activation of stress pathways.
A study of nearly half a million women found that endometriosis was associated with a higher risk of ovarian cancer. The risk was particularly elevated among women with ovarian endometriomas or deep infiltrating endometriosis, with a 19-fold increased risk for certain types of ovarian cancer.
A new study found that increased exposure to residential greenery during midlife can help stave off cognitive decline. Higher average exposure to greenness was linked to higher levels of cognitive function and slower cognitive decline, particularly among people living in low-socioeconomic status and highly populated neighborhoods.
A retrospective cohort study found hormone-modulating therapy protected against Alzheimer's disease and related dementias in postmenopausal women with breast cancer. The protective effect varied by age and race, with greater benefit for Black women under 75.
A new study suggests that lowering systolic blood pressure below 120 mmHg over time may produce slight health-protective benefits against late-life dementia. The study found that middle-aged adults who lower their systolic blood pressure, particularly Black and Latino individuals, had a reduced risk of developing dementia.
A recent study published in JAMA Pediatrics highlights the critical role of family support in maintaining the mental health of transgender youth following gender identity milestones. Without a supportive family environment, these young individuals are at a higher risk of attempting suicide or running away from home.
Researchers used movement sensors to track thoroughbreds' stride patterns and identified miniscule changes associated with increased injury risk. The technology has been shown to prevent catastrophic injuries by alerting trainers and veterinarians to intervene before a major injury occurs, resulting in longer careers for affected horses.
A new study by researchers at WashU Medicine found that people of predominantly Native American or African ancestry have a higher prevalence of dementia due to social determinants of health. These factors include lower education levels, rural residency, and high blood pressure, which raised their risk of cognitive decline.
A large cohort study in Canada found an association between prenatal ambient PM2.5 exposure and increased cerebral palsy risk in offspring. Further research is needed to understand this association and potential biological pathways.
A recent analysis found that nearly half of US counties lack a cardiologist, exacerbating rural-urban health disparities. Counties without cardiologists tend to be more rural, socioeconomically disadvantaged, and experience higher cardiovascular mortality rates.
Researchers found GLP-1 receptor agonists lower risks of certain obesity-associated cancers in patients with type 2 diabetes, suggesting potential benefits for cancer prevention in high-risk populations. The study provides preliminary evidence supporting further preclinical and clinical studies to prevent specific obesity-linked cancers.
A large-scale genetic survey found that genes can influence the risk of developing atrial fibrillation. Researchers analyzed over 400,000 individuals and identified six genes whose genetic changes significantly affect a person's risk.
A study published in JAMA Ophthalmology found an association between semaglutide and nonarteritic anterior ischemic optic neuropathy, a condition that can cause vision loss. The observational study suggests caution when prescribing semaglutide to patients at risk of this condition.
A Swedish researchers have created a questionnaire test that quickly identifies individuals at high risk of heart attack. The test has been shown to be as accurate as blood tests and blood pressure measurements, detecting 65% of those at the highest risk of cardiovascular disease.
Scientists at the University of Warwick have investigated a range of contributing risk factors for suicide in a large-scale study. The study identified biological and behavioral predictors, including elevated white blood cells, neuroticism, childhood experiences, and reduced grey matter in the brain.
A recent study investigated COVID-19 vaccine exposure in the first trimester and its potential impact on major structural birth defects. The results indicate that mRNA COVID-19 vaccine exposure during this period is not associated with an increased risk for selected birth defects among live births.
A phase 2 study found fluorine-18 PSMA-1007 PET/computed tomography to be superior to multiparametric MRI for locoregional staging of prostate cancer. The technology supports its use in the preoperative workflow for intermediate-risk and high-risk tumors.
Long-term exposure to air pollution is associated with a higher need for help with lost independence in later life. Traffic-related sources generate the largest and most consistent increases in risk, suggesting controlling air pollution may delay or divert care needs.
Research emphasizes the impact of parental factors on offspring's health outcomes. The study discovered a significant association between parents' weight status at 17 and their children's risk of obesity. This finding suggests that health issues can be inherited across generations, with parental characteristics playing a crucial role.
A large US cohort study found no association between multivitamin use and reduced mortality risk. The study included over 200,000 participants and analyzed data from three prospective cohorts.
A Canadian Journal of Cardiology review article finds that plant-based meat alternatives tend to reflect a heart-healthy dietary pattern, improving cholesterol levels and blood pressure. The authors recommend incorporating PBMAs into a healthy diet as an excellent protein source, with options lower in saturated fat and sodium.
A new study led by UCL researchers found that cardiovascular health is a significant risk factor for future dementia rates. The study analyzed data from 27 papers and found that rates of obesity and diabetes have increased over time, contributing to higher dementia risk.
A study found that a cuffless wrist monitor provides hundreds of readings in days, enabling clinicians to determine cardiovascular risk and improve hypertension care. The device's continuous readings help confirm diagnosis and guide medication titration, potentially revolutionizing hypertension management.
A survey study found that transgender men are particularly vulnerable to all forms of violence, highlighting the need for targeted prevention and intervention services. The results emphasize the importance of policies protecting trans and gender-diverse individuals from discriminatory violence.
A cohort study of 10,634 participants reveals that childhood risk factors are associated with adult cardiovascular disease. The study highlights the importance of intervening in childhood to reduce the incidence of adult CVD, particularly for body mass index (BMI) and low-density lipoprotein cholesterol.
Research highlights need for prevention and treatment approaches for children with obesity born underweight, finding links between low birth weight and cardiometabolic disease risks. Visceral fat storage issues contribute to type 2 diabetes risk.
A new study by UCL researchers found that people with anxiety over the age of 50 are at least twice as likely to develop Parkinson's disease. The study, published in the British Journal of General Practice, also identified symptoms such as depression, sleep disturbance, and fatigue as risk factors for developing the condition.
A cohort study found that cannabis use was an independent risk factor for COVID-19-related complications, even after considering other risk factors. The study suggests that cannabis may increase the risk of severe illness and hospitalization due to COVID-19.
A recent study published in the International Review of Financial Analysis suggests that cryptocurrencies are not completely disconnected from economic risks. The research found that during turbulent periods like the COVID-19 pandemic and Ukraine war, cryptocurrency prices experienced increased volatility.
Researchers found auto-antibodies against type I interferons in severe and critical COVID-19 patients, compromising their immune response. This discovery highlights the importance of detecting these auto-antibodies in regular health checkups to better prepare for viral infections.
A study by Boston University School of Public Health found that over 1 in 10 FQHC patients experience major social risk factors such as food insecurity, housing insecurity, and financial strain. These challenges are significantly higher among FQHCs serving historically disenfranchised groups.
Families with germline CDH1 P/LP variants show a cumulative risk of gastric cancer between 7-10% and breast cancer in female carriers at 37%
Researchers developed a computational method to estimate sudden cardiac death risk using one-minute heart rate measurements at rest. The new method provides a significantly better estimate than previous analyses, identifying differences in heart rate intervals between high-risk and healthy patients.
Researchers developed a metabolic health score based on clinical parameters and used it to explore its genetic underpinnings in mice, validating findings in human data. The study identified two significant genetic regions linked to metabolic health and pinpointed candidate genes associated with metabolic traits.
A new study found that adolescents with higher rates of prediabetes often experience adverse social determinants of health, such as food insecurity and low household income. Screening for these non-medical factors may help identify youth at risk of progressing to type 2 diabetes.
A comprehensive study by researchers at the University of Córdoba found that teachers' commitment to inclusive education positively impacts students' socio-emotional skills. The study, involving over 3,500 students and 294 teachers, reveals the decisive role of teachers in boosting social-emotional skills through inclusive education.
Researchers have discovered a better way to identify those at high risk of potential heart attacks and strokes by adding genetic information to health checks. The study found that combining clinical risk scores with polygenic risk scores significantly improves identification rates, especially among younger people.
A new study reveals that depression and antidepressant use are associated with an increased risk of all-cause mortality in postmenopausal women. Epigenetic age acceleration, measured by GrimAge DNA methylation age acceleration, partially mediates the relationship between antidepressant use and increased mortality risk.
In individuals with a diabetes duration of 10 years or less, bariatric metabolic surgery was associated with greater weight loss and reduced mortality compared to first-generation GLP-1RAs. No differences were observed between treatment modalities in patients with longer diabetes duration.
Research published in the Stroke journal found that teenage women who were overweight or obese had a higher risk of ischemic stroke before age 55. The study analyzed data from over 50 years and suggested that even temporary excess weight may have long-term health effects.
A large health system study found cannabis use was prevalent among primary care patients, with most using it to manage health-related symptoms. The study suggests clinicians could benefit from integrating cannabis use information to assess patient risk for cannabis use disorder.
By 2050, at least 61% of US adults (184 million people) are projected to have some type of cardiovascular disease, with total costs tripling to $1.8 trillion. Population shifts, high blood pressure, and obesity will drive this increase.
The US Preventive Services Task Force recommends exercise interventions for older adults at increased risk of falls, considering prior falls, medical conditions, and patient values. The overall net benefit is small, making a personalized approach necessary to balance benefits and harms.
A study found that nearly 20% of breast cancer survivors experience excess weight gain of more than 10% over six years. Factors associated with this weight gain include lower body weight, younger age, hormone-positive breast cancer, and certain genetic mutations.
Higher Mediterranean diet adherence was associated with a significant reduction in all-cause mortality risk. The study found that cardiometabolic factors played a partial role in this inverse association.