Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
A cross-sectional study found that approximately 50% of cancer survivors experience financial hardship, with social vulnerability playing a key role in increasing levels of hardship. Younger, Medicare or Medicaid beneficiaries, and those with advanced disease are particularly vulnerable to financial strain.
A new national study reveals significant regional variations in the likelihood of being diagnosed with Alzheimer's disease or another form of dementia. Despite controlling for demographic and population-level risk factors, the study found that differences in diagnostic intensity persist across regions.
A new study found that bone fracture rates in older women differ dramatically by race, with White women having the highest risk. Hispanic women had a lower risk of 10%, while Asian-American women experienced varying fracture rates depending on their ethnicity. The study highlights the need to better understand factors behind these diff...
A uterus transplant was successfully performed on women with absolute uterine-factor infertility, resulting in a high live birth rate. However, the procedure was also associated with significant medical and surgical risks for both recipients and donors.
A University of Gothenburg study found that work-related stress, particularly job conflicts and lack of influence, significantly increase the risk of future sick leave. Women who experienced these stressors were more than twice as likely to take sick leave, with adjusted factors indicating a significant impact on their wellbeing.
A study suggests that higher levels of UV radiation in areas with limited sunshine are associated with a drop in deaths due to cardiovascular disease and cancer. Sunbed use was also found to be linked to a reduced risk of these deaths, but further research is needed to confirm the findings.
A new Cleveland Clinic study reveals that diet-derived molecules called metabolites are the main drivers of young-onset colorectal cancer risk, particularly those associated with red and processed meat. The research suggests that addressing diet with doctors can help prevent colon cancer in younger adults.
A cohort study found that PTSD is a modifiable risk factor for a modest reduction in microvascular complications in veterans with comorbid PTSD and type 2 diabetes. The study suggests further research is needed to confirm findings in non-Veterans Health Administration settings.
A UK cohort study reveals that even low-risk alcohol consumption is linked to increased mortality among older adults with health-related or socioeconomic risk factors. The findings suggest that healthier lifestyles may play a role in the observed attenuation of mortality for wine drinkers and those who drink only during meals.
A global study predicts significant increases in cancer cases and deaths among men between 2022 and 2050, with widening disparities by age and country's economic status. Disparities are projected to worsen, with poorer survival rates observed among older men and those living in low-human development index countries.
A recent study analyzing over 1.5 million patients' electronic health records found that mild cognitive impairment (MCI) is significantly underdiagnosed in rural areas of West Michigan. Researchers discovered a higher rate of MCI skippers, where patients progress directly to dementia without a prior diagnosis, in these communities.
A new heart MRI technique accurately estimates pressures inside the heart to predict heart failure risk in a general population. Key risk factors identified include age over 70, high blood pressure, obesity, alcohol consumption, and male gender.
A cohort study found an association between cannabis-related disorder and the development of head and neck cancer. The study highlights the need for further research on the mechanism of this association and dose response to support evidence of cannabis use as a risk factor.
Commonly prescribed oral antibiotics increase risk of serious cutaneous adverse drug reactions compared to macrolides. Sulfonamides and cephalosporins carry the highest risk, prompting prescribers to opt for lower-risk alternatives when clinically appropriate.
Discrepancies in e-cigarette products containing nicotine analogues may lead to uncertainty about user exposure, hindering risk assessment for clinical and regulatory purposes. The largely unknown acute and chronic inhalation hazards and addictive potential of nicotine analogues pose a significant concern.
A University of Michigan-led study found that higher levels of metals in blood and urine are associated with a greater risk for ALS and shorter survival. Occupational exposure to metals was also linked to increased metal levels, emphasizing the need for accounting for environmental factors when evaluating overall exposure risk.
Research published in the Journal of Nutrition Education and Behavior found that meals from community cafés had significantly higher diet quality than meals not eaten at the café, measured by the Healthy Eating Index. This improvement was particularly pronounced for individuals with very low food security. The study suggests that commu...
Maintaining stable hemoglobin A1c levels in individualized target ranges may lower Alzheimer disease and related dementias risk. Lower HbA1c time in range could identify patients at increased risk of these conditions.
Researchers have identified nearly 300 common and over 20 rare genetic variants as significant risk factors for schizophrenia. The study emphasizes the role of multiple genes rather than single-gene causation, revealing complexity in the mechanisms underlying the disorder.
A cohort study found that aspirin use was associated with a greater absolute reduction in risk of colorectal cancer among individuals with less healthy lifestyles. Lifestyle risk factors may help identify those with a more favorable risk-benefit profile for cancer prevention with aspirin.
A new study suggests that public health interventions, such as reformulating food products and introducing low emission zones, could yield significant cost savings and QALY gains in England. The interventions studied could save up to £4bn by reducing dementia rates and helping people live longer and healthier.
A recent survey study found increased self-managed abortion attempts following federal abortion protection changes in the US. The study revealed that marginalized groups predominantly used ineffective methods, highlighting the need for expanded access to safe and effective abortion care.
A recent study found that mental health disparities in Los Angeles County worsened during the COVID-19 pandemic, particularly among non-white residents. The risk of depression grew more common in areas hit hardest by deaths from COVID-19, with stark divisions observed between white and non-white communities.
A new model developed by Penn State researchers more accurately predicts the causal relationship between genetic and environmental factors in disease development. The study found that lifestyle and environmental factors play a larger role than previously believed, offering new opportunities to mitigate disease risk.
Infants born to mothers with obesity are at higher risk of SUID due to a dose-dependent association between increasing maternal BMI and SUID risk. Research suggests that maternal obesity should be added to the list of known risk factors for SUID.
The PD GENEration study has found that 13% of participants have a genetic form of Parkinson's disease, significantly higher than previous estimates. The study, which reached its goal of 15,000 participants ahead of schedule, provides insights into the genetics of the disease and its potential for precision medicine.
A recent study published in ESC Heart Failure found that kidney dysfunction can be used as a criterion to stratify patients requiring implantable defibrillators. The research identified two key independent predictors for the risk of sudden cardiac death: left ventricular ejection fraction and estimated glomerular filtration rate.
Researchers studied Alzheimer disease blood biomarkers and found a strong association with incident all-cause dementia risk. Biomarker levels increased with age and were linked to dementia starting in midlife.
Women with bilateral mastectomy have a greatly diminished risk of contralateral breast cancer, yet experience similar mortality rates as patients treated with lumpectomy or unilateral mastectomy. The study highlights the importance of considering long-term risks and benefits in breast cancer treatment decisions.
A prospective cohort study found that both chronic and new anxiety were associated with a higher risk of developing dementia. The presence of chronic anxiety was linked to a 2.8-time higher risk, while new onset anxiety was associated with a 3.2-time higher risk.
A new study found that the incidence of hepatitis C virus (HCV) reinfection among men with HIV is 10-fold higher than primary infection rates in New York City. The researchers identified receiving semen in the rectum as the only risk factor for reinfection, contradicting previous assumptions about transmission routes.
A new University of Michigan study found that over 82% of Americans aged 50-80 take one or more prescription medications, with 80% open to stopping certain drugs. However, researchers stress the importance of personalized guidance for deprescribing older adults, particularly those taking medication for cardiovascular disease or diabetes.
A large population-based case-control study found a small increased risk of composite adverse outcomes with long-term oral corticosteroid use among individuals with atopic dermatitis. Health professionals must weigh benefits against potential risks, and monitor for adverse events.
Researchers found that anxiety disorders and depression significantly elevate the risk of incident DVT. Stress-related neural mechanisms may increase DVT risk through heightened activation of stress pathways.
A study of nearly half a million women found that endometriosis was associated with a higher risk of ovarian cancer. The risk was particularly elevated among women with ovarian endometriomas or deep infiltrating endometriosis, with a 19-fold increased risk for certain types of ovarian cancer.
A new study found that increased exposure to residential greenery during midlife can help stave off cognitive decline. Higher average exposure to greenness was linked to higher levels of cognitive function and slower cognitive decline, particularly among people living in low-socioeconomic status and highly populated neighborhoods.
A retrospective cohort study found hormone-modulating therapy protected against Alzheimer's disease and related dementias in postmenopausal women with breast cancer. The protective effect varied by age and race, with greater benefit for Black women under 75.
A new study suggests that lowering systolic blood pressure below 120 mmHg over time may produce slight health-protective benefits against late-life dementia. The study found that middle-aged adults who lower their systolic blood pressure, particularly Black and Latino individuals, had a reduced risk of developing dementia.
A recent study published in JAMA Pediatrics highlights the critical role of family support in maintaining the mental health of transgender youth following gender identity milestones. Without a supportive family environment, these young individuals are at a higher risk of attempting suicide or running away from home.
Researchers used movement sensors to track thoroughbreds' stride patterns and identified miniscule changes associated with increased injury risk. The technology has been shown to prevent catastrophic injuries by alerting trainers and veterinarians to intervene before a major injury occurs, resulting in longer careers for affected horses.
A new study by researchers at WashU Medicine found that people of predominantly Native American or African ancestry have a higher prevalence of dementia due to social determinants of health. These factors include lower education levels, rural residency, and high blood pressure, which raised their risk of cognitive decline.
A large cohort study in Canada found an association between prenatal ambient PM2.5 exposure and increased cerebral palsy risk in offspring. Further research is needed to understand this association and potential biological pathways.
A recent analysis found that nearly half of US counties lack a cardiologist, exacerbating rural-urban health disparities. Counties without cardiologists tend to be more rural, socioeconomically disadvantaged, and experience higher cardiovascular mortality rates.
Researchers found GLP-1 receptor agonists lower risks of certain obesity-associated cancers in patients with type 2 diabetes, suggesting potential benefits for cancer prevention in high-risk populations. The study provides preliminary evidence supporting further preclinical and clinical studies to prevent specific obesity-linked cancers.
A large-scale genetic survey found that genes can influence the risk of developing atrial fibrillation. Researchers analyzed over 400,000 individuals and identified six genes whose genetic changes significantly affect a person's risk.
A study published in JAMA Ophthalmology found an association between semaglutide and nonarteritic anterior ischemic optic neuropathy, a condition that can cause vision loss. The observational study suggests caution when prescribing semaglutide to patients at risk of this condition.
A Swedish researchers have created a questionnaire test that quickly identifies individuals at high risk of heart attack. The test has been shown to be as accurate as blood tests and blood pressure measurements, detecting 65% of those at the highest risk of cardiovascular disease.
Scientists at the University of Warwick have investigated a range of contributing risk factors for suicide in a large-scale study. The study identified biological and behavioral predictors, including elevated white blood cells, neuroticism, childhood experiences, and reduced grey matter in the brain.
A recent study investigated COVID-19 vaccine exposure in the first trimester and its potential impact on major structural birth defects. The results indicate that mRNA COVID-19 vaccine exposure during this period is not associated with an increased risk for selected birth defects among live births.
A phase 2 study found fluorine-18 PSMA-1007 PET/computed tomography to be superior to multiparametric MRI for locoregional staging of prostate cancer. The technology supports its use in the preoperative workflow for intermediate-risk and high-risk tumors.
Long-term exposure to air pollution is associated with a higher need for help with lost independence in later life. Traffic-related sources generate the largest and most consistent increases in risk, suggesting controlling air pollution may delay or divert care needs.
Research emphasizes the impact of parental factors on offspring's health outcomes. The study discovered a significant association between parents' weight status at 17 and their children's risk of obesity. This finding suggests that health issues can be inherited across generations, with parental characteristics playing a crucial role.
A large US cohort study found no association between multivitamin use and reduced mortality risk. The study included over 200,000 participants and analyzed data from three prospective cohorts.
A Canadian Journal of Cardiology review article finds that plant-based meat alternatives tend to reflect a heart-healthy dietary pattern, improving cholesterol levels and blood pressure. The authors recommend incorporating PBMAs into a healthy diet as an excellent protein source, with options lower in saturated fat and sodium.
A new study led by UCL researchers found that cardiovascular health is a significant risk factor for future dementia rates. The study analyzed data from 27 papers and found that rates of obesity and diabetes have increased over time, contributing to higher dementia risk.
A study found that a cuffless wrist monitor provides hundreds of readings in days, enabling clinicians to determine cardiovascular risk and improve hypertension care. The device's continuous readings help confirm diagnosis and guide medication titration, potentially revolutionizing hypertension management.
A survey study found that transgender men are particularly vulnerable to all forms of violence, highlighting the need for targeted prevention and intervention services. The results emphasize the importance of policies protecting trans and gender-diverse individuals from discriminatory violence.
A cohort study of 10,634 participants reveals that childhood risk factors are associated with adult cardiovascular disease. The study highlights the importance of intervening in childhood to reduce the incidence of adult CVD, particularly for body mass index (BMI) and low-density lipoprotein cholesterol.
Research highlights need for prevention and treatment approaches for children with obesity born underweight, finding links between low birth weight and cardiometabolic disease risks. Visceral fat storage issues contribute to type 2 diabetes risk.
A new study by UCL researchers found that people with anxiety over the age of 50 are at least twice as likely to develop Parkinson's disease. The study, published in the British Journal of General Practice, also identified symptoms such as depression, sleep disturbance, and fatigue as risk factors for developing the condition.