Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
A University of Virginia engineer developed a workflow to combine advanced imaging technologies for improved understanding of porous bone, which could inform disease detection. The method allows for three-dimensional rendering of bone structure across various length scales.
A large study found that women with premature ovarian insufficiency are 2.6 times more likely to have an autoimmune disorder, with some conditions increasing the risk by 26 times. The study suggests a strong link between POI and severe autoimmune diseases, highlighting the need for medical professionals to be aware of this increased risk.
A study found that children with Down's syndrome have an elevated number of red blood cells, which increases their risk of developing leukemia. The extra chromosome 21 alters DNA packing and gene regulation, contributing to the development of leukemia.
A study suggests that semaglutide may have therapeutic value in preventing opioid overdoses by reducing the associated risk. The results require further validation, but the findings indicate a potential benefit for patients with comorbid type 2 diabetes and opioid use disorder.
Researchers analyzed over 6,400 tweets from young male Twitter users and found that posts using humor to stigmatize people or promote risky behaviors received more attention. The study's findings suggest that understanding how at-risk populations discuss HIV on social media can help design effective health campaigns to reach them.
Treatment-emergent nirmatrelvir resistance mutations were commonly detected in immunosuppressed individuals, but at low frequencies and transient nature. The study suggests a low risk for the spread of nirmatrelvir resistance in the community with current variants and drug usage patterns.
A study found that galactic cosmic radiation can cause long-lasting learning deficits in female rodents, but an antioxidant compound reduced this impact. The findings contribute to a broader understanding of radiation's long-term impact on cognitive health.
The 2024 guideline provides comprehensive recommendations for assessing cardiovascular disease risk and managing patients taking SGLT2-inhibitors. It also highlights the importance of judicious screening and evidence-based management of cardiovascular conditions before, during, and after noncardiac surgery.
A new study reveals a significant increase in e-bike and powered scooter injuries between 2019 and 2022, with rates rising by 293% and 88%, respectively. The research highlights the need to improve micromobility injury surveillance and identify strategies for cities to promote safe user practices.
A Mount Sinai study links prediabetes among young people with a higher likelihood of gestational diabetes and hypertensive disorders during pregnancy. The findings highlight the need for clear clinical guidance on screening and counseling youth with elevated blood glucose levels.
A new study found that nursing shortages result in longer hospital stays and worse patient outcomes, including higher mortality rates. Understaffing by registered nurses and nurse assistants is associated with increased risks of adverse events, such as readmissions, deep vein thrombosis, pneumonia, and pressure ulcers.
A new study demonstrates the potential of semaglutide in treating hidradenitis suppurative (HS) in people with obesity. The results show marked improvements in patient outcomes across several key measures, including reduced flare frequency, improved quality of life, and better glycaemic control.
A third of living former professional football players reported perceived chronic traumatic encephalopathy (CTE) associated with an increased prevalence of suicidality. Men with CTE had cognitive impairment and more health problems compared to those without CTE, highlighting a novel risk factor for suicidality.
A new study found that up to 10 million people in the US could qualify for Medicare-covered semaglutide injections, depending on their level of cardiovascular risk. Those with higher risk scores would be eligible for full or partial coverage, potentially expanding access to this life-saving medication.
A systematic review of risk stratification tools found high-sensitivity troponin tests to have the highest diagnostic accuracy for ruling out acute coronary syndrome. However, these findings require further validation before recommending their use in primary care settings.
Research found that patients leaving hospital prematurely, known as 'before medically advised' (BMA) discharge, have a significantly higher risk of drug overdose in the following month. This increase is due to factors such as persistent pain and untreated addiction after hospital discharge.
A cohort study found a significant association between maternal influenza infection during pregnancy and an increased risk of childhood seizures. The study suggests that maternal influenza may affect childhood neurological development, particularly for febrile seizures, but not epilepsy.
A recent study found a correlation between PrEP use and increased rates of gonorrhea, chlamydia, and syphilis among gay and bisexual men in Ontario. The study highlights the importance of regular STI testing and risk reduction measures to manage this risk effectively.
A remote monitoring program called DIG IT improved blood pressure control and reduced heart disease risk in underserved patients. The study found that patients who used the program had a 31-point average drop in systolic blood pressure and nearly 73% reached their blood pressure goals within three months.
A new poll from Michigan Medicine shows that nearly half of people age 50 and older plan to get the updated COVID-19 vaccine. However, some older adults with high risk of severe illness appear unlikely to seek the vaccine, highlighting the need for increased encouragement from clinicians and other sources.
A new risk prediction model identifies patients with advanced cancer who are at highest risk for unplanned emergency room visits and hospital stays. The model, developed by researchers from the SWOG Cancer Research Network, considers factors such as performance status, comorbidities, and cancer type.
A systematic review and meta-analysis of over 3.6 million mother-child pairs found that maternal obesity during pregnancy significantly linked with psychiatric and behavioral problems in children later in life, including autism spectrum disorder and attention deficit hyperactivity disorder.
A nationwide cohort study revealed a higher risk of placental problems, premature births, and severe bleeding in subsequent deliveries following uterine artery embolization. Babies born to mothers who underwent UAE also had a higher chance of major birth defects, particularly heart problems.
A study found that stroke rates are rising among adults with SCD, despite established treatment guidelines, with age being a significant factor. The researchers identified modifiable risk factors such as high blood pressure, high cholesterol, and frequent hospitalization as increasing the risk of ischemic stroke.
A study from the University of Copenhagen detected lipid biomarkers in obese children that indicate a higher risk of developing type 2 diabetes, liver, and heart disease later in life. A one-year lifestyle intervention lowered these biomarkers, demonstrating the importance of early intervention for children with obesity.
A new blood test using lipids could identify children at risk of complications from obesity, including type two diabetes, liver disease, and heart disease. The test uses mass spectrometry to assess a broader range of lipid molecules, offering a more accurate early warning system.
Researchers analyzed over 150,000 COVID-19 cases in Japan and found CAPA occurred in 0.4% to 2.7% of severe or critical patients, with higher risk seen in men, older adults, and those with respiratory diseases. Early detection and treatment with antifungal drugs are crucial for improved outcomes.
A study finds that cardiometabolic indicators like metabolic syndrome and diabetes impair coronary microvascular function, increasing cardiovascular risk. The presence of subclinical atherosclerosis also contributes to altered microvessel function.
Researchers report significant strides in enhancing early diagnosis of bipolar disorder in adolescents by combining multimodal MRI with behavioral assessments. This approach reveals specific changes in brain networks signaling early-stage bipolar disorder, potentially leading to better and more personalized treatments. The study's find...
A pioneering study identified critical biomarkers that can predict disability worsening in MS. Elevated serum neurofilament light chain and serum glial fibrillary acidic protein levels correlate with progression independent of relapse activity, guiding personalized treatment approaches.
A recent study published in JAMA Network Open found that optimizing body mass index (BMI) from preconception to early pregnancy can improve fertility outcomes, including reduced miscarriage risk. The research suggests that maintaining a healthy BMI may be an important strategy for women and men seeking to conceive.
A new study provides further evidence that SARS-CoV-2, the virus responsible for COVID-19, likely originated from animals sold at the Huanan Seafood Market in Wuhan, China. The analysis of genetic data found that wildlife species such as raccoon dogs and civet cats were present at the market and may have carried the virus.
A recent study reveals a strong link between styrene and ethylbenzene exposure and the development of type 2 diabetes mellitus. Exposure to these environmental pollutants significantly elevates the risk of T2DM, with individuals having high exposure levels facing a substantially increased risk.
A new study found that patients with 4 or 5 identified risk factors, including age 18-24 years and schizophrenia spectrum disorders, had over 100 times the incidence of Neuroleptic Malignant Syndrome. The data provide a basis for early identification and monitoring of children and youth at elevated risk.
Researchers from Brigham and Women's Hospital used advanced machine learning to increase the accuracy of a national cardiovascular risk calculator while preserving its interpretability. The results showed higher accuracy overall in an electronic health records cohort, reclassifying one out of ten patients into a different risk category.
A recent study found significant therapeutic inertia in the treatment of women with multiple sclerosis (MS), leading to delayed or reduced use of disease-modifying treatments. The research highlights gender disparities that could impact long-term health outcomes for women of childbearing age, particularly due to concerns about pregnanc...
The global stroke burden has increased significantly over the past three decades, driven by rising levels of air pollution, high temperatures, and metabolic risk factors. The study found that the number of people experiencing new strokes rose to 11.9 million in 2021, with an additional 93.8 million survivors and 7.3 million deaths.
A new study by UT Health San Antonio found that higher levels of leptin are associated with better signal-transmitting brain white matter in middle-aged adults. The researchers also discovered a link between leptin bioavailability and reduced risk of cognitive impairment, providing potential insights into obesity's role in dementia.
A cohort study of 1.5 million patients found that at-risk groups are disproportionately affected by denied claims for preventive services, perpetuating unequal access to high-value healthcare.
A new study finds that four unhealthy behaviors, including smoking and physical inactivity, contribute significantly to socioeconomic disparities in coronary artery disease mortality. The researchers conclude that targeted public health policies can help reduce these disparities and improve heart health for low-income individuals.
A landmark study has identified novel ancestry-specific genetic variants linked to multiple sclerosis (MS) risk, offering new insights for treatment approaches. The research highlights the potential of ancestry-informed genetic studies to uncover previously unidentified risk factors for MS.
Researchers found that cancer survivors with overweight or obesity are more likely to develop a second cancer, especially obesity-related ones. This study highlights the importance of promoting weight management and increasing awareness of second cancers among physicians and cancer patients.
A study by Tarang Parekh found small but significant improvements in capturing social determinants of health using Internal Classification of Diseases codes. This breakthrough research aims to better understand the impact of social factors on health outcomes and target interventions more effectively.
A new study found that childhood trauma can have specific consequences for biological health and risk of developing 20 major diseases later in life. The study's findings differ by sex and type of stressor, highlighting the need for a precision medicine approach based on patients' sex and specific stress profile.
A new study presented at ECTRIMS 2024 reveals that initiating monoclonal antibody therapy during childhood can lead to improved long-term outcomes for children with MS. The research showed a substantially lower risk of progressing to higher disability levels in the early treatment group, particularly in moderate disability range.
A new AI-based system has been shown to reduce the risk of unexpected deaths in hospitalized patients by identifying those at high risk of deteriorating health. The system, CHARTWatch, uses real-time alerts and enhanced communication between nurses and physicians to support high-quality care.
A new study by University of Illinois Chicago researchers found that high levels of toxic metals in urine predicted faster increases in blood sugar. Individuals with highest arsenic exposure qualified as prediabetic 23 months earlier and diabetic 65 months earlier than those with lowest exposure.
Neighborhood food access in early life is strongly associated with child BMI and obesity trajectories. Residence in low-income areas with limited access to healthy food options increases the risk of severe obesity.
A new study by University of Oklahoma researchers identifies key measurements of brain blood flow and ability to compensate as better predictors of mild cognitive impairment than traditional risk factors. The findings provide hope for preventing or treating memory problems early before they progress to dementia.
A nationwide multi-cohort study found that residence in low-income-low-food-access neighborhoods during pregnancy or early childhood significantly raises the risk of obesity and severe obesity from childhood to adolescence. The study underscores the importance of early-life neighborhood environments in shaping child health outcomes.
A population-based study found that air pollution may lower Parkinson disease risk by modifying the disease phenotype and reducing dyskinesia. The study suggests a potential connection between air quality and Parkinson's disease progression.
A new scientific statement emphasizes the role of social determinants, such as immigration status, socioeconomic position, and access to healthcare, in shaping cardiovascular health among Asian American adults. The statement identifies future research directions to advance health equity and reduce disparities in these communities.
Researchers will conduct laboratory and field work at UC Medical Center to detect airborne transmission of MRSA. The study aims to better understand the significance of airborne transmission of MRSA and inform enhanced workplace safety measures.
A global increase in testing for lipoprotein(a) is recommended due to one in five people being at risk of cardiovascular diseases. The test can help identify individuals who would benefit from medication that lowers the lipid particle significantly.
A new study shows that urban forests within walkable distance from residential areas are crucial in reducing heat-related health risks. Researchers found that nearby forests have a pronounced impact on reducing mortality risks, particularly those within 1 kilometre of residential areas.
Researchers are decoding genetic mutations in high-risk genes for neurodevelopmental and psychiatric disorders, including schizophrenia and depression. A new collaborative project aims to characterize the genetic origins of these disorders using human stem cells.
A study by McLean Hospital found that high doses of amphetamine increase the risk of new-onset psychosis or mania in adults. The risk is highest for those taking 30 mg or more of dextroamphetamine, with an 81% attributable risk percentage.
Researchers found an association between consuming foods with lower nutritional quality and a higher risk of cardiovascular diseases, particularly myocardial infarction and stroke. The study used the latest version of the Nutri-Score algorithm and included over 345,000 participants from seven European countries.
A study published by The BMJ found that one dose of modified vaccinia Ankara-Bavarian Nordic (MVA-BN) smallpox vaccine is moderately effective in preventing mpox infection. The vaccine showed an estimated 58% vaccine effectiveness against mpox, suggesting it should be made available to communities at risk.
A new study from Cornell University and the New York State Department of Environmental Conservation reveals bald eagles are most vulnerable to lead poisoning from bullet fragments, with many species at risk due to scavenging deer carcasses. The researchers used bald eagles as a bioindicator for ongoing monitoring of lead hazards.