Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
Research found that iron oxide nanoparticles reduce the lifespan, longevity, and reproductive ability of Enchytraeus crypticus in a 202-day study. Population density may influence nanoparticle toxicity, with lower-density groups experiencing greater harm.
A recent study found that children born to mothers with polycystic ovary syndrome (PCOS) are at a higher risk of lower birth weight, shorter stature, and smaller head circumference. The researchers believe that the placenta's inability to meet the baby's demands due to PCOS-related hormonal imbalances may be the cause.
A recent study published in Topics in Stroke Rehabilitation found that slightly overweight stroke survivors (BMI 22.1-27.5 kg/m²) have a lower risk of sustaining disabilities compared to those with normal weight. The research suggests that a higher-than-normal BMI may be beneficial for recovering from a stroke with less disability.
A new study published in The Lancet Child & Adolescent Health found that children living in areas with a high burden of tuberculosis have a consistently high annual risk of developing TB infection throughout childhood. By age 10, over 10% of children developed TB disease.
Researchers analyzed data from 26 countries, revealing that Mondays have the highest suicide risk, while New Year's Day increases risk across all nations. Men are also more vulnerable to day-of-the-week and holiday-related variations in suicide risk.
A cohort study found that hospital COVID-19 burden was associated with an increased risk of in-hospital adverse effects among patients with and without COVID-19. The results highlight the importance of hospitals having greater resilience and surge capacity to prevent declines in patient safety during surges in demand.
A digital health behavior intervention improved child weight-for-length trajectory and reduced childhood obesity at 24 months. The intervention was effective in a racially and ethnically diverse population, including groups at elevated risk for childhood obesity.
Light ex-smokers experience a CVD risk reduction similar to never-smokers within years of smoking cessation. Heavy ex-smokers require longer periods, up to 25 years, for their residual CVD risk to align with that of never-smokers.
Upgrading home insulation can lower medical bills and extend healthy lives by reducing blood pressure and CVD risk. Simulations showed that upgrading or retrofitting insulation is cost-effective for many homeowners, with significant health benefits justifying the costs.
This study highlights the importance of lipoprotein(a) in predicting atherosclerotic cardiovascular disease risk. Higher Lp(a) levels are associated with increased risk of CVEs, particularly in high-risk patients. Measuring and managing Lp(a) may help decrease CVE risk in these individuals.
A study reveals that infant gut microbiota succession is predictable and malleable, allowing for the shaping of gut health through birth mode and feeding practices. This research has significant implications for reducing childhood allergic diseases, overweight, and respiratory infections.
A new study from the University of Toronto finds that childhood neglect is associated with a range of mental and physical health problems in adulthood. The presence of a supportive adult and higher socioeconomic status largely attenuate this relationship.
A Michigan Medicine study of over 18,500 adults found that obstructive sleep apnea was associated with a higher risk of dementia symptoms or diagnosis at every age level. Women were more likely to be diagnosed with dementia than men, especially as they aged.
Research reveals that antenatal corticosteroids can lead to smaller volumes of key brain areas in preterm infants, affecting emotion processing and motor control. The study suggests a delicate balance between benefits for respiratory health and potential risks to neurological development.
The American Academy of Otolaryngology calls on battery manufacturers to produce safe button or coin cell batteries to mitigate life-threatening risks. Swallowing a battery can cause severe burns, perforations, and damage to the esophagus, trachea, or major vasculature.
Researchers found that polypharmacy in older adults with Alzheimer's disease exacerbates symptoms, functional decline, and health outcomes. The study highlights the need for medication optimization strategies to improve quality of life among this vulnerable population.
Researchers will use decades-old data from blood and urine tests to measure pesticide and metal levels among participants, then match with MRI scans and cognitive tests to identify potential contributions to dementia risk. The study aims to understand environmental links to Alzheimer's disease and related dementias.
A study published in JAMA Psychiatry found a significant association between genetic predisposition and sexual trauma with increased risk for schizophrenia, bipolar disorder, and major depression. The research highlights the importance of considering social and environmental factors in human genetics studies.
Low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe. Exposure to lead can result in an annual loss of 765 million IQ points in children globally.
Researchers analyzed data from 1971 to 2019 and found that Mondays and New Year's Day were universally correlated with elevated suicide risk. In contrast, weekends and other public holidays varied by region, highlighting the importance of recognizing temporal fluctuations in risk for preventive actions.
A new survey by Ohio State University shows that most people believe pancreatic disease affects only the elderly and that there is nothing they can do to reduce their risk. However, obesity increases lifetime risk for pancreatic cancer by 20%.
Researchers propose a comprehensive biomarker-based approach to assess cardiovascular risk by combining markers of chronic inflammation with cardiac health indicators. This approach reveals the significant impact of aging-related inflammation, or 'inflammaging,' on heart health and opens new avenues for targeted interventions.
Researchers have identified 44 genetic regions associated with metabolite levels in the body, which can influence cardiovascular risk. The study found a potential molecular mechanism by which six genetic loci are linked to cardiovascular risk through the metabolites they regulate.
Research shows that animals, including humans, can become less sociable as they age to avoid diseases and parasites. This phenomenon, known as social ageing, may bring benefits, such as reduced competition and increased safety.
Researchers at UCLA Health found an association between childhood attention problems and increased psychosis risk, with genetic variants acting as a middleman. The study used data from over 10,000 children to explore the relationship between attention span variability and psychotic-like symptoms.
Research from Karolinska Institutet finds that abnormal BMI in children can lead to impaired lung function, but normalizing BMI before adulthood may offset this. The study, which followed over 4,000 children, also found a correlation between low BMI and reduced lung growth.
Elevated body mass index (BMI) was associated with a significantly increased post-acute sequelae of SARS-CoV-2 infection risk. The study highlights the need for targeted care to prevent chronic conditions in at-risk children and young adults.
A study found that nearly one-third of individuals from Ghana and Nigeria carry APOL1 variants that significantly increase the risk of chronic kidney disease. The researchers also discovered that having a single copy of the APOL1 gene increases the risk by 18%, while two copies increase it by 25%.
The study found a significant decrease in the percentage of adolescents reporting current marijuana use, from 23.1% in 2011 to 15.8% in 2021. Marijuana use was most prevalent among 12th graders, with a notable decline in usage rates across all grades.
Researchers from NUS and Harvard T.H. Chan School of Public Health found that breastfeeding significantly reduces cardiovascular disease risk among women with type 2 diabetes and gestational diabetes. A healthy Mediterranean diet with low persistent organic pollutant exposure also lowers the risk of GDM.
Research highlights social media's impact on youth mental health, including associations between excessive social media use and suicidal thoughts. The study emphasizes the need for targeted interventions and policy changes to address this growing concern among young people.
Medically induced weight loss with GLP-1 receptor agonists can lead to substantial muscle loss, compromising physical strength and immune function. The authors emphasize the need for a multimodal approach combining medication with exercise and nutritional interventions to preserve muscle mass.
A new meta-analysis suggests that almost a third of asthma cases are attributable to long-term exposure to fine particulate matter (PM2.5), with significant health impacts on children and adults. The study highlights the urgent need for policymakers to combat air pollution through stringent legislation.
Researchers developed an algorithm that splits obesity into 5 separate diagnostic profiles with contrasting risk of developing obesity complications. This can help clinicians identify individuals who need early interventions, improving disease prediction and treatment.
A study by Dr. Hernan Bazan at Ochsner Health reveals that higher frailty scores are directly associated with increased rates of stroke, death, and myocardial infarction within 30 days of the carotid procedure. The Hospital Frailty Risk Index provides a systematic tool for assessing frailty risk across large populations.
A new study finds that prolonged exposure to arsenic in water contributes to the development of ischemic heart disease. Decade-long arsenic exposure up to the time of a cardiovascular disease event was associated with the greatest risk. The study suggests stronger regulations would provide significant benefits to the population.
A study published by the American Academy of Neurology found that middle-aged people with uncontrolled risk factors and poor lifestyle habits are at a higher risk of stroke, dementia, or depression. The study's results highlight the importance of adopting healthy lifestyle choices to promote brain health.
Scientists found that sleep deprivation during early life can negatively impact key brain functions, leading to lasting effects on behavior and social skills. The study also suggests that genetic risk for autism spectrum disorder can interact with sleep disruption to cause long-lasting changes.
A cohort study examines how traumatic and adverse childhood experiences influence developmental changes in psychiatric risk and cognitive ability. The findings suggest targeted early prevention and intervention strategies for at-risk youth.
Researchers at Rutgers University found that people who took multiple courses of penicillin antibiotics had a modestly lower risk of developing Parkinson's disease. The study analyzed medical records from over 93,000 people in the UK and found an inverse dose-response relationship between antibiotic use and Parkinson's risk.
A new study has found that rifaximin, an antibiotic commonly prescribed for liver disease patients, is driving the emergence of a deadly superbug. The antibiotic triggers specific changes in bacteria that make them resistant to last-resort antibiotics like daptomycin.
The use of GLP-1 receptor agonists (GLP-1RAs) and SGLT2 inhibitors in people with type 1 diabetes has significantly increased between 2010 and 2023. This trend is driven by their benefits in weight management and cardiorenal protection, but caution is advised due to concerns about euglycemic diabetic ketoacidosis.
A three-decade study found polar bears exposed to increased pathogens due to environmental changes, with females at higher risk. The study, published in PLOS ONE, highlights the need for further disease screening in polar bear populations.
A new Concordia study reveals that bilingualism is associated with larger and healthier hippocampi in patients with Alzheimer’s disease. The research found no evidence of hippocampal atrophy in bilinguals across the continuum of Alzheimer’s development.
A UK study found that menopausal hormone therapy may have moderate effects on brain health, but these depend on past surgical history, treatment duration, and age at last use. The research revealed no significant differences in brain health between women who used MHT and those who did not, but those on MHT had higher grey and white-mat...
A new remote tool has been developed to detect autism and developmental delay in children. The Kids’ Development Diagnosis methodology was adapted into a mobile app, allowing for swift and efficient diagnosis. This digital tool can help prevent lifelong impacts of early intervention.
Research finds that people with schizophrenia are at a significantly higher risk of sudden cardiac death, with a lifetime risk 4+ times higher than the general population. The study also suggests that mental health disorders can lead to shortened lifespan and increased risk of other causes of death.
A new AI-powered model has been developed to predict kidney transplant outcomes with high accuracy, offering hope for more efficient organ allocation and improved patient outcomes. The tool, UK-DTOP, outperforms existing methods in predicting outcomes for deceased-donor kidney transplants.
A large cohort study found that mothers with eating disorders were more likely to have children with psychiatric disorders, while those with pre-pregnancy BMI outside the normal range also showed an increased risk. The findings suggest that clinicians should consider these factors when preventing offspring mental illness.
Researchers from Amsterdam UMC have developed a way to predict which patients are at risk of epilepsy after a cerebral venous sinus thrombosis (CVT), a rare type of stroke. The prediction model, known as the DIAS3 score, is based on six indicators and can be accessed online for healthcare providers worldwide.
A new clinical guideline from the American Stroke Association outlines strategies to support brain health and prevent stroke throughout a person's lifespan. The guideline recommends regular health screenings, identifying risk factors, lifestyle interventions, and medications to reduce the risk of a first stroke.
A new study found that initial prescriptions of benzodiazepines for older stroke survivors often include excessive doses, posing a risk of dependence, falls, and other harmful effects. Guidelines recommend avoiding benzodiazepine prescriptions if possible, but some cases may require limited use under close monitoring.
A new study conducted by researchers at the University of Pennsylvania School of Nursing found a strong association between handheld cellphone use and risky driving behaviors among newly licensed teen drivers. The study identified potential safety risks and recommended strategies to avoid cellphone use while driving.
The study found that individuals receiving methadone had a lower risk of treatment discontinuation compared to those receiving buprenorphine/naloxone. Additionally, the risk of mortality while receiving treatment was similar between medications, with no significant differences observed.
Researchers have found that women are more likely to die from postoperative complications after high-risk cardiovascular surgery, with a failure to rescue rate of 10.7% compared to 8.6% for men. The quality of hospital where the procedure was performed did not affect this disparity.
Individuals with multiple long-term conditions are two and a half times more likely to die following COVID-19 infection compared to those without. Among children, the risk increases to nearly three times that of those without multiple long-term conditions.
A recent study analyzing data from the ANCORS-YW study found that overweight and obese women in this region are at a higher risk of hypertension and cardiovascular disease. Researchers recommend tailored preventive strategies, including lifestyle modification programs and socioeconomic support, to address this public health challenge.
Miscarriage affects 15-20% of pregnancies, causing devastating effects. Outpatient early pregnancy assessment clinics can provide compassionate and tailored care, but services are lagging.
The risk of medical leave in Spain on days of extreme heat decreased from 19% to 13% between 1989 and 2019, according to a study by the Barcelona Institute for Global Health. Workers in agriculture and hospitality sectors remain most vulnerable to heat-related injuries.
Researchers found that certain factors increased the risk of death after sepsis, including advanced age, dementia, heart disease, cancer, and previous hospitalizations. A total of 50.6% of patients with sepsis died within two years, highlighting the need for closer monitoring and follow-up care.