Articles tagged with Risk Factors
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A new poll from Michigan Medicine shows that nearly half of people age 50 and older plan to get the updated COVID-19 vaccine. However, some older adults with high risk of severe illness appear unlikely to seek the vaccine, highlighting the need for increased encouragement from clinicians and other sources.
A new risk prediction model identifies patients with advanced cancer who are at highest risk for unplanned emergency room visits and hospital stays. The model, developed by researchers from the SWOG Cancer Research Network, considers factors such as performance status, comorbidities, and cancer type.
A systematic review and meta-analysis of over 3.6 million mother-child pairs found that maternal obesity during pregnancy significantly linked with psychiatric and behavioral problems in children later in life, including autism spectrum disorder and attention deficit hyperactivity disorder.
A nationwide cohort study revealed a higher risk of placental problems, premature births, and severe bleeding in subsequent deliveries following uterine artery embolization. Babies born to mothers who underwent UAE also had a higher chance of major birth defects, particularly heart problems.
A study found that stroke rates are rising among adults with SCD, despite established treatment guidelines, with age being a significant factor. The researchers identified modifiable risk factors such as high blood pressure, high cholesterol, and frequent hospitalization as increasing the risk of ischemic stroke.
A study from the University of Copenhagen detected lipid biomarkers in obese children that indicate a higher risk of developing type 2 diabetes, liver, and heart disease later in life. A one-year lifestyle intervention lowered these biomarkers, demonstrating the importance of early intervention for children with obesity.
A new blood test using lipids could identify children at risk of complications from obesity, including type two diabetes, liver disease, and heart disease. The test uses mass spectrometry to assess a broader range of lipid molecules, offering a more accurate early warning system.
Researchers analyzed over 150,000 COVID-19 cases in Japan and found CAPA occurred in 0.4% to 2.7% of severe or critical patients, with higher risk seen in men, older adults, and those with respiratory diseases. Early detection and treatment with antifungal drugs are crucial for improved outcomes.
A study finds that cardiometabolic indicators like metabolic syndrome and diabetes impair coronary microvascular function, increasing cardiovascular risk. The presence of subclinical atherosclerosis also contributes to altered microvessel function.
Researchers report significant strides in enhancing early diagnosis of bipolar disorder in adolescents by combining multimodal MRI with behavioral assessments. This approach reveals specific changes in brain networks signaling early-stage bipolar disorder, potentially leading to better and more personalized treatments. The study's find...
A pioneering study identified critical biomarkers that can predict disability worsening in MS. Elevated serum neurofilament light chain and serum glial fibrillary acidic protein levels correlate with progression independent of relapse activity, guiding personalized treatment approaches.
A recent study published in JAMA Network Open found that optimizing body mass index (BMI) from preconception to early pregnancy can improve fertility outcomes, including reduced miscarriage risk. The research suggests that maintaining a healthy BMI may be an important strategy for women and men seeking to conceive.
A new study provides further evidence that SARS-CoV-2, the virus responsible for COVID-19, likely originated from animals sold at the Huanan Seafood Market in Wuhan, China. The analysis of genetic data found that wildlife species such as raccoon dogs and civet cats were present at the market and may have carried the virus.
A recent study reveals a strong link between styrene and ethylbenzene exposure and the development of type 2 diabetes mellitus. Exposure to these environmental pollutants significantly elevates the risk of T2DM, with individuals having high exposure levels facing a substantially increased risk.
A new study found that patients with 4 or 5 identified risk factors, including age 18-24 years and schizophrenia spectrum disorders, had over 100 times the incidence of Neuroleptic Malignant Syndrome. The data provide a basis for early identification and monitoring of children and youth at elevated risk.
Researchers from Brigham and Women's Hospital used advanced machine learning to increase the accuracy of a national cardiovascular risk calculator while preserving its interpretability. The results showed higher accuracy overall in an electronic health records cohort, reclassifying one out of ten patients into a different risk category.
A recent study found significant therapeutic inertia in the treatment of women with multiple sclerosis (MS), leading to delayed or reduced use of disease-modifying treatments. The research highlights gender disparities that could impact long-term health outcomes for women of childbearing age, particularly due to concerns about pregnanc...
The global stroke burden has increased significantly over the past three decades, driven by rising levels of air pollution, high temperatures, and metabolic risk factors. The study found that the number of people experiencing new strokes rose to 11.9 million in 2021, with an additional 93.8 million survivors and 7.3 million deaths.
A new study by UT Health San Antonio found that higher levels of leptin are associated with better signal-transmitting brain white matter in middle-aged adults. The researchers also discovered a link between leptin bioavailability and reduced risk of cognitive impairment, providing potential insights into obesity's role in dementia.
A cohort study of 1.5 million patients found that at-risk groups are disproportionately affected by denied claims for preventive services, perpetuating unequal access to high-value healthcare.
A new study finds that four unhealthy behaviors, including smoking and physical inactivity, contribute significantly to socioeconomic disparities in coronary artery disease mortality. The researchers conclude that targeted public health policies can help reduce these disparities and improve heart health for low-income individuals.
A landmark study has identified novel ancestry-specific genetic variants linked to multiple sclerosis (MS) risk, offering new insights for treatment approaches. The research highlights the potential of ancestry-informed genetic studies to uncover previously unidentified risk factors for MS.
Researchers found that cancer survivors with overweight or obesity are more likely to develop a second cancer, especially obesity-related ones. This study highlights the importance of promoting weight management and increasing awareness of second cancers among physicians and cancer patients.
A study by Tarang Parekh found small but significant improvements in capturing social determinants of health using Internal Classification of Diseases codes. This breakthrough research aims to better understand the impact of social factors on health outcomes and target interventions more effectively.
A new study found that childhood trauma can have specific consequences for biological health and risk of developing 20 major diseases later in life. The study's findings differ by sex and type of stressor, highlighting the need for a precision medicine approach based on patients' sex and specific stress profile.
A new study presented at ECTRIMS 2024 reveals that initiating monoclonal antibody therapy during childhood can lead to improved long-term outcomes for children with MS. The research showed a substantially lower risk of progressing to higher disability levels in the early treatment group, particularly in moderate disability range.
A new AI-based system has been shown to reduce the risk of unexpected deaths in hospitalized patients by identifying those at high risk of deteriorating health. The system, CHARTWatch, uses real-time alerts and enhanced communication between nurses and physicians to support high-quality care.
A new study by University of Illinois Chicago researchers found that high levels of toxic metals in urine predicted faster increases in blood sugar. Individuals with highest arsenic exposure qualified as prediabetic 23 months earlier and diabetic 65 months earlier than those with lowest exposure.
Neighborhood food access in early life is strongly associated with child BMI and obesity trajectories. Residence in low-income areas with limited access to healthy food options increases the risk of severe obesity.
A new study by University of Oklahoma researchers identifies key measurements of brain blood flow and ability to compensate as better predictors of mild cognitive impairment than traditional risk factors. The findings provide hope for preventing or treating memory problems early before they progress to dementia.
A nationwide multi-cohort study found that residence in low-income-low-food-access neighborhoods during pregnancy or early childhood significantly raises the risk of obesity and severe obesity from childhood to adolescence. The study underscores the importance of early-life neighborhood environments in shaping child health outcomes.
A population-based study found that air pollution may lower Parkinson disease risk by modifying the disease phenotype and reducing dyskinesia. The study suggests a potential connection between air quality and Parkinson's disease progression.
A new scientific statement emphasizes the role of social determinants, such as immigration status, socioeconomic position, and access to healthcare, in shaping cardiovascular health among Asian American adults. The statement identifies future research directions to advance health equity and reduce disparities in these communities.
Researchers will conduct laboratory and field work at UC Medical Center to detect airborne transmission of MRSA. The study aims to better understand the significance of airborne transmission of MRSA and inform enhanced workplace safety measures.
A global increase in testing for lipoprotein(a) is recommended due to one in five people being at risk of cardiovascular diseases. The test can help identify individuals who would benefit from medication that lowers the lipid particle significantly.
A new study shows that urban forests within walkable distance from residential areas are crucial in reducing heat-related health risks. Researchers found that nearby forests have a pronounced impact on reducing mortality risks, particularly those within 1 kilometre of residential areas.
Researchers are decoding genetic mutations in high-risk genes for neurodevelopmental and psychiatric disorders, including schizophrenia and depression. A new collaborative project aims to characterize the genetic origins of these disorders using human stem cells.
A study by McLean Hospital found that high doses of amphetamine increase the risk of new-onset psychosis or mania in adults. The risk is highest for those taking 30 mg or more of dextroamphetamine, with an 81% attributable risk percentage.
Researchers found an association between consuming foods with lower nutritional quality and a higher risk of cardiovascular diseases, particularly myocardial infarction and stroke. The study used the latest version of the Nutri-Score algorithm and included over 345,000 participants from seven European countries.
A study published by The BMJ found that one dose of modified vaccinia Ankara-Bavarian Nordic (MVA-BN) smallpox vaccine is moderately effective in preventing mpox infection. The vaccine showed an estimated 58% vaccine effectiveness against mpox, suggesting it should be made available to communities at risk.
A new study from Cornell University and the New York State Department of Environmental Conservation reveals bald eagles are most vulnerable to lead poisoning from bullet fragments, with many species at risk due to scavenging deer carcasses. The researchers used bald eagles as a bioindicator for ongoing monitoring of lead hazards.
A cross-sectional study found that over 50% of adults with uncontrolled hypertension in the US are unaware of their condition and untreated. Despite treatment, 70.8% of patients experience persistent uncontrolled hypertension, highlighting a need for improved healthcare strategies to address this critical public health issue.
A new study published in Health Data Science reveals that both spontaneous and induced abortions are associated with an increased risk of premature mortality. The research found that induced abortions were strongly linked to cardiovascular death, while spontaneous abortions also elevated the risk of all-cause premature mortality.
A large-scale population analysis confirms tirzepatide's similar gastrointestinal tolerability to other GLP-1 medications without increased risk of diabetic retinopathy, medullary thyroid cancer, or pancreatitis. Researchers analyzed real-world evidence from the FDA adverse event reporting system database and found that tirzepatide has...
A recent study published in JACC: Clinical Electrophysiology found that quitting smoking can significantly lower the risk of atrial fibrillation, with former smokers having around 13% lower risk and current quitters having an 18% lower risk. The benefits of quitting are seen shortly after stopping smoking.
The study found that semaglutide was effective in preventing heart attacks and other major adverse cardiovascular events as well as death in adults with impaired kidney function. The results showed a significant reduction in cardiovascular disease risk with semaglutide, even among those with poor kidney function.
This cross-sectional study examines the relationship between neighborhood opportunity and preterm birth rates, finding disproportionate exposure by race and ethnicity. The study suggests that addressing neighborhood opportunity may be a modifiable factor contributing to racial and ethnic inequities in preterm birth.
Researchers found that women exposed to higher levels of nitrogen dioxide and inhalable particulate matter during the second trimester face an almost fourfold increased risk of postpartum depression. The study also discovered a sustained effect of air pollution on symptoms of depression for up to three years after birth.
A new study estimates nearly 10.5 million U.S. adults have A-Fib, a three-fold increase from previous estimates. Early detection and treatment can reduce its adverse outcomes.
A new trial revealed that a lifestyle-intervention program failed to reduce cardiovascular risk factors in US South Asians, but showed promising improvements in health behaviors. The study underscores the need for culturally tailored interventions to address the unique health needs of this growing ethnic group.
A new study published in the journal JCI Insight found that male mice fed high-cholesterol diets have increased cardiovascular disease risk in their female offspring. The researchers used a novel method to study sperm small RNA and discovered altered molecules that affect gene expression in early embryonic stem cells.
A new study finds that excessive social media use is associated with a higher risk of eating disorder symptoms in 9-14-year-olds, including binge eating and distress over weight gain. Problematic screen use may contribute to unhealthy behaviors and addictive tendencies.
A new preclinical blood test identifies adults most likely to develop severe respiratory conditions, including chronic obstructive pulmonary disease (COPD), by analyzing 32 proteins that accurately predict lung health data. The risk score indicates a high likelihood of hospital care, COPD development, and respiratory disease death.
A new study found that rural regions in Ontario have significantly higher rates of eating disorders among adolescents and young adults. The researchers suggest that stigma and socio-cultural dynamics may contribute to these disparities, highlighting the need for targeted interventions such as telehealth services.
A $15 million gift from Sally Ross Soter will support the Go Red for Women Venture Fund, investing in health companies targeting cardiovascular, metabolic, and neurologic solutions for women. The fund aims to close the gap in women's health investment and translate research into better patient care.
Researchers at UCSF identified signals in the metabolic system of infants who died from Sudden Infant Death Syndrome (SIDS), finding associations between lower C-3 levels and elevated C-14OH. Elevated biomarkers also led to reduced risk of SIDS, but further research is needed to validate these findings.
A case-control study found an association between abnormal birth metabolic analytes and sudden infant death syndrome, suggesting potential early risk identification. The study's findings could inform future research and clinical efforts focused on monitoring and preventing SIDS.
Research links impaired circadian heart rate fluctuations to microvascular disease and increased long-term risk of cardiovascular mortality in people with diabetes. Disrupted daily heart rate variations are associated with a doubled risk of dying from cardiovascular causes.
A new study found that skin cancer incidence in young adults declined in Sweden around 2015. The decrease in incidence and mortality is attributed to increased awareness of sun protection, reduced access to sunbeds, and changes in lifestyle habits such as spending more time indoors. The study suggests that continued emphasis on sun pro...
Research suggests that eating fruit, oats, and rye in childhood increases the risk of developing type 1 diabetes, but consuming berries may lower this risk. The study followed thousands of children in Finland from birth to age six and found associations between specific foods and an increased or decreased risk of islet autoimmunity.