PSD502 demonstrates significant time to ejaculation and ejaculatory control improvements, with a 5.5-fold increase in IELT, compared to placebo. Men treated with PSD502 experience reduced premature ejaculation symptoms and increased satisfaction.
The REDUCE trial found dutasteride to be effective in reducing the chance of a positive biopsy by 23% and preventing disease progression. However, more detailed analyses are needed to monitor long-term effects on cardiovascular health and selectively identify aggressive disease.
The European Association of Urology does not recommend mass screening for prostate cancer in Europe, citing the risk of overdiagnosis and overtreatment. Men should be properly informed by their physician about the pros and cons of screening, such as a PSA test.
The European Association of Urology (EAU) has launched new and updated clinical guidelines for urological conditions, including muscle-invasive and metastatic bladder cancer and prostate cancer. The guidelines provide evidence-based recommendations on diagnosis, staging, treatment options, and follow-up care.
Several urological experts were awarded prestigious medals and prizes for their groundbreaking work, including Prof. Frans Debruyne and Prof. James Catto. The awards recognized their efforts to advance urology through innovative technologies and research.
UK researchers found that many urologists fail to diagnose and treat Chlamydia in young men, despite clear guidelines. In a survey of five teaching hospitals, only 7% of cases were tested for Chlamydia, and most received inadequate treatment.
A study found that prostate cancer treatment options differ based on the type of specialist consulted. Men who see a radiation oncologist are more likely to receive radiation therapy, while those who consult with a urologist with or without a medical oncologist are treated more frequently with hormone therapy, watchful waiting, or radi...
A nationwide Swedish study found no increased risk of suicide among men diagnosed with early nonpalpable prostate cancer detected by PSA testing. However, those with locally advanced or metastatic disease faced a twice-higher suicide rate compared to the general male population.
A new study published in The Journal of Urology found that open radical prostatectomy (ORP) and laparoscopic radical prostatectomy (LRP) have similar rates of postoperative mortality and morbidity. LRP was associated with shorter hospital stays and a lower risk of bladder neck or urethral obstruction.
A systematic review found that neonatal and infant circumcision by trained staff rarely results in problems, with relatively minor adverse events being low among infants under one year old. However, complications are more common when performed by inexperienced providers or with subpar equipment.
A systematic review found that neonatal and infant circumcision is relatively safe, with minor adverse events common but severe complications rare. The risk of complications increases with inexperienced providers or inadequate equipment, highlighting the need for improved training and safety measures.
The groundbreaking Videourology journal offers fully peer-reviewed video demonstrations of the latest urologic surgical techniques and technologies. The journal provides comprehensive search options, including videos organized by medical condition, anatomy, and surgical procedure.
A study of 129 patients found high rates of infection and mechanical failure with inflatable prostheses; however, hydraulic devices remain the best option for achieving voiding while standing and sexual intercourse. The choice of device may favor two-piece over three-piece designs.
A systematic review found IAD to be as effective as continuous androgen deprivation while improving survival rates and sexual potency. The approach has been a valid treatment option for nonmetastatic PCa cases, offering key tolerability and quality of life benefits.
A prospective case-control survey found that male factor infertility is associated with a higher rate of medical comorbidities, as objectively scored with the Charlson Comorbidity Index. The study suggests that men with male factor infertility may be less healthy than age-comparable fertile men, regardless of their underlying causes.
A large study found that PSA velocity has little predictive value for determining the outcome of a first prostate biopsy. However, a rapid rise in PSA levels may still suggest prostatitis or prostate cancer, warranting further evaluation. The findings suggest that clinical judgment should be used to guide biopsy decisions.
A new study published in The Journal of Urology found a significant association between psychiatric disorders, sexual trauma, and lower urinary tract symptoms (LUTS) in women. Women with psychiatric comorbidities and history of sexual trauma were more likely to experience LUTS such as incontinence and overactive bladder.
A survey found that 75% of surgical patients would consider allowing a competent unsupervised trainee to perform their entire operation if it meant they could have it done more quickly. Most respondents felt trainees needed to operate under supervision to improve skills, but were willing for supervised trainees to do procedures.
The periurethral suspension technique results in significantly greater continence rates at 3 months after robot-assisted laparoscopic radical prostatectomy (RALP). The median/mean interval to recovery of continence was also statistically significantly shorter in the suspension group.
The European Association of Urology has published an evidence-based guideline for incontinent urostomy, offering expert guidance for nurses. The comprehensive 80-page document covers topics such as cystectomy, pre- and post-operative care, and community follow-up, providing best practices for managing this complex condition.
Researchers identified that even among high-risk groups, only a few individuals had invasive bladder cancer, highlighting the need to find a higher-risk group to benefit from screening. Abstaining from smoking is crucial in preventing bladder cancer.
The July issue of European Urology reviews prostate cancer screening studies, highlighting the need to balance mortality reduction with overdiagnosis risks. The EAU adopts the conclusions of the ERSPC study and recognizes the benefit of screening for mortality reduction.
The AUA Foundation has awarded the 2009 Astellas Rising Stars in Urology to William Roberts, MD and Edward Schaeffer, MD for their groundbreaking research projects on Benign Prostatic Hyperplasia and Phospholipase A2 signaling in prostate development. The award aims to support young urologists in pursuing careers in urologic research.
A new study published in The Journal of Urology found a significant association between lower urinary tract symptoms and metabolic syndrome. Researchers analyzed data from over 1,900 men and discovered that those with mild to severe LUTS were more likely to suffer from MetS.
A new study by Johns Hopkins Medicine finds that Roux-en-Y weight loss surgery nearly doubles the risk of developing kidney stones, with an overall risk of around 8 percent. The researchers suggest that doctors can help prevent kidney stones through calcium supplements and other interventions.
Research reveals that HGPIN carries a high predictive value for future diagnosis of prostate cancer, with a 41.8% risk identified in patients. The study recommends delaying first repeat biopsies at low PSA ranges but shorter intervals for intermediate and higher PSA ranges.
The Phase 3 IMPACT trial found that sipuleucel-T significantly prolonged overall survival by 4.1 months and improved three-year survival by 38 percent compared to placebo. This innovative immunotherapy reduced the risk of death by 22.5 percent.
The American Urological Association recommends PSA testing for men aged 40+, considering factors like family history and overall health. The new guidelines stress that prostate cancer is an individual decision, and the single standard should not apply to all men.
The American Urological Association recommends individualized PSA testing for men 40 years or older with a life expectancy of at least 10 years. The test should be accompanied by a digital rectal exam to determine prostate cancer risk, which also considers family history and overall health.
A study published by the American Urological Association found that well water intake is directly associated with bladder cancer incidence in women and mortality rates in both sexes. In contrast, exposure to solar UV radiation is inversely associated with bladder cancer incidence and mortality rates in both men and women. Cigarette smo...
A study found that elderly patients experiencing nighttime urination had a higher mortality rate compared to those without nocturia. Researchers identified several factors associated with an increased risk of death, including age, diabetes, and hypertension.
Researchers have established criteria for reclassifying prostate cancer risk over time, allowing for more tailored treatment approaches. Patients with slow-growing cancer can benefit from reduced therapy burden, while those with more aggressive disease receive definitive care.
Researchers found that tadalafil improved detrusor pressure and bladder function in men with BPH-LUTS. The study also showed a significant reduction in obstructed patients after treatment with tadalafil.
Research suggests that diet soda's citrate and malate can inhibit calcium stone development, a known factor for kidney stones. Moderate consumption of diet soda may benefit patients with recurrent kidney stones.
Long-term studies found that melamine consumption increases the risk of developing kidney stones in children, particularly between six months to 18 months old. Non-invasive treatment can effectively manage these complications with a high success rate.
A new topical spray, PSD502, has been found to be an effective treatment for premature ejaculation, improving latency time from 0.6 minutes to 4 minutes in clinical trials. The spray selectively desensitizes penile skin without affecting sensation, making it a potentially attractive option for patients with this condition.
Researchers have identified two potential new targets in the fight against prostate cancer: 'cold shock' proteins that can be turned down through genetic techniques to weaken cancer cells, and higher bone density in men which may increase their risk of developing prostate cancer. Additionally, children with kidney stones are more likel...
A new robotic approach to surgically treat urothelial cancer of the kidney is proving to be effective, offering benefits such as less bleeding and scarring, shorter hospital stays, and faster recovery times. The minimally invasive surgery allows for the preservation of kidney function in patients with stage 3 chronic kidney disease.
A study of 181 women found that increased sexual activity, recent alcohol consumption, and using sanitary napkins during menstruation were associated with an increased risk of developing their first urinary tract infection (UTI). Medical attention is crucial as UTIs can lead to kidney infections and sepsis.
A study published by the American Urological Association found that obesity is associated with a higher risk of urinary tract infections. Morbidly obese patients were most at risk, highlighting the importance of urologic care for individuals with elevated body mass indexes.
Researchers investigated a novel nanoparticle platform that releases therapeutic levels of nitric oxide, which aids in erection biology. Five out of seven rats treated with these nanoparticles experienced positive effects on erectile response, resulting in visible erections.
Two studies show that adult circumcision reduces the risk of contracting HIV and coital injuries, but does not affect sexual function. Circumcision removes skin surface susceptible to HIV infection, reducing the risk of transmission.
Researchers found uterus sparing surgery to be an effective treatment option for women with pelvic organ prolapse, with 82.97% patient satisfaction rates. The study also showed minimal persisting symptoms, with sexual activity maintained in 95.5% of patients.
A study reviewing 505 operative repairs found that prompt treatment improved survival rates, with extent of fibrosis being the only predictive factor for successful repair. Women with previous pregnancies showed significantly improved outcomes compared to first-time mothers.
Researchers confirmed that transplanting autologous muscle-derived cells into the bladder improves symptoms and quality of life in patients with stress urinary incontinence. The treatment has few side effects and significantly improved symptoms, with 76.5% of patients reporting a reduction in stress leaks at 12 months.
Researchers found that a three-year combination therapy of vitamin E, selenium, and soy did not prevent the progression from HGPIN to prostate cancer. The study results show that 26.4% of participants developed invasive prostate cancer, regardless of baseline characteristics.
A long-term clinical trial found that men who consumed pomegranate juice daily after treatment for localized prostate cancer experienced a significant increase in PSA doubling time and a decline in median PSA slope. This suggests that pomegranate juice may effectively slow the progression of post-treatment prostate cancer recurrence.
A study of 1,495 veterans found that those exposed to Agent Orange had a nearly 50% increased risk of prostate cancer recurrence and more aggressive cancers. This highlights the need for closer monitoring and timely intervention in these patients.
The American Institute of Ultrasound in Medicine (AIUM) has recognized Fred Winsberg, Martin Resnick, and Horace Thompson as pioneers in the field of ultrasound in medicine. Drs. Winsberg and Resnick were renowned experts in radiology and urology, respectively, while Dr. Thompson is considered the
Researchers found that collagen injections can improve symptoms of stress urinary incontinence (SUI) in some patients, even after surgical treatment fails. The procedure involves injecting collagen into the tissue surrounding the urethra to tighten the sphincter and prevent leakage.
The European Association of Urology has released new clinical guidelines for kidney cancer treatment, emphasizing the use of targeted agents and nephron-sparing surgery. The guidelines recommend first-line therapies for low- and intermediate-risk patients, as well as second-line options for high-risk patients.
The new guideline encourages healthy men to talk to their doctors about using 5-alpha reductase inhibitors (5-ARIs) to prevent prostate cancer, with a 25% relative risk reduction in most men. ASCO developed a Decision Aid Tool to help patients and families understand the risks and benefits of 5-ARIs.
A Johns Hopkins study found that older men with PSA levels less than 3 nanograms per milliliter are unlikely to die of or experience aggressive prostate cancer. This suggests that routine PSA testing may be unnecessary for some older men, potentially reducing costs and morbidity.
Researchers developed nomograms to predict long-term kidney transplant success and refine patient selection for living donor transplants. The models analyzed over 20,000 cases and identified key donor and recipient characteristics impacting transplant outcomes.
A commonly-prescribed drug for men suffering from pelvic pain failed to significantly reduce symptoms in a 12-week international study. Researchers can now focus on more promising therapies.
The International Society of Andrology, European Association of Urology, and other scientific organizations have formulated new recommendations on late-onset hypogonadism (LOH) treatment. These guidelines emphasize the importance of addressing symptoms such as erectile dysfunction and low testosterone levels in aging men.
Surgeons at the University of Chicago Medical Center have successfully performed the world's first pediatric robotic bladder reconstruction, using the DaVinci system. The innovative technique resulted in good outcomes and minimal complications, with the patient regaining full control over her bladder after six weeks.
A recent study published in European Urology found a significant relationship between prostate inflammation and lower urinary tract symptoms (LUTS) in men. The study, which analyzed data from the REDUCE trial, revealed that chronic inflammation was associated with higher IPSS scores and a greater degree of LUTS.
A new prostate cancer gene test using a urine sample has shown promising results in detecting the disease at an early stage. The test, PCA3, is highly specific to PCa and may allow patients to avoid unnecessary biopsies.
A multi-centre study of 863 patients from 14 countries found that solifenacin significantly improved overactive bladder symptoms, with a 70% reduction in severe urgency and urgency incontinence. Patients reported reduced urine frequency and fewer incontinence episodes within three days.