Articles tagged with Urology
Researchers presented findings on Maxi-K gene therapy, showing it to be safe and restoring erectile function in men with moderate to severe ED. The treatment has been shown to enhance sexual behavior, including increases in partial and full erections and a two-fold increase in erection duration.
Researchers predict a rise in kidney stone disease due to global warming, with a potential cost of $1 billion annually by 2050. The southern US is expected to see an expansion of the
The International Society for Sexual Medicine (ISSM) has established an evidence-based definition of premature ejaculation, which is characterized by early ejaculation and negative personal consequences. This new definition aims to improve diagnosis and treatment options for men suffering from premature ejaculation, allowing them to se...
A new study reveals that prostate cancer screening programs and access to urologists are significantly linked to reduced mortality rates. The research, presented at the AUA 2008 conference, found that higher urologist population densities and PSA screening rates correlate with lower mortality rates.
Researchers found that a single PSA reading taken at age 44-50 can predict prostate cancer diagnosis up to 30 years subsequently, even in men below age 40. The study suggests possible prolonged periods of prostate cancer pre-malignancy and the relationship between PSA and advanced cancer development.
Researchers from Tengion, Inc., present a new study suggesting that growing a replacement organ using the patient's own cells could be an effective and safe treatment option. The technique involves seeding bladder progenitor cells on a biodegradable scaffold, which can then be implanted into the patient.
Men aged 75-80 with PSA levels below 3 ng/ml are unlikely to develop aggressive disease and may safely discontinue screening. The study's findings could lead to a reduction in unnecessary treatment for non-aggressive prostate cancers.
A new therapeutic vaccine has shown promising results in prolonging survival and improving the quality of life for men with metastatic prostate cancer. The adenovirus/PSA vaccine demonstrated strong immune responses to PSA, leading to improved patient outcomes.
A study of 1,214 men prescribed cholesterol-lowering drugs found that PSA levels decreased after starting statins and correlated with LDL cholesterol decline. The results suggest a potential role for cholesterol in prostate cancer development and progression.
A new study strengthens the association between exposure to Agent Orange and an increased risk of developing prostate cancer in aging Vietnam veterans. The study found that twice as many exposed men were diagnosed with prostate cancer, diagnosed at a younger age, and more likely to present with aggressive disease.
Researchers developed nanoparticles consisting of metallic iron with a protective carbon coat that could serve as a safe and effective hyperthermia agent. The carbon coating prevented the iron from rusting, allowing heating at greater temperatures and reducing cytotoxic effects on normal cells.
Researchers found that patients with high LDL cholesterol and increased serum cholesterol were up to 2.5 times more likely to experience a biochemical relapse after radical prostatectomy. Poor cholesterol management may affect not only prostate cancer risk but also biomedical recurrence after surgery.
Research suggests patients with metabolic syndrome disorders may be more likely to develop uric-acid stones. The study also found that patients presenting with uric acid stones could benefit from additional health screenings to identify related arteriosclerotic diseases.
A new study by researchers at the University of California, San Francisco found that retired firefighters are at a higher risk of developing bladder cancer. The study, which tested 1,286 active and retired San Francisco firefighters, found two cases of transitional cell carcinoma (TCC) among the participants.
A study found that external-beam radiation therapy for localized prostate cancer increases the rate of secondary malignancies, including a 3.0-fold increase in bladder cancer, compared to radical prostatectomy. This predisposition is observed in lung-cancer resections and rectal cancer as well.
In Iraq, penetrating bladder injuries from IEDs and bullets were common among civilians treated at Al Yarmouk Teaching Hospital. Most patients (78.1%) were injured by bullets, with associated bowel injury present in nearly all cases.
Researchers from Germany and Austria used muscle-derived stem cells to repair damaged sphincters. Patients showed significant improvements in continence, with some being completely continent after treatment.
A new study confirms that black women have less urinary incontinence than white women, but when they do develop it, the condition tends to be more severe. The study also found that black women experience 'urge incontinence' twice as often as white women.
Researchers have discovered that chewing gum stimulates smooth muscle fibers and salivary gland secretion, aiding in bowel movement recovery after surgery. The study involved 102 patients undergoing gastrointestinal surgery, with those who chewed gum experiencing faster recovery times.
A new Mayo Clinic study found that removing the entire kidney from younger patients with small kidney tumors may lead to decreased overall survival. In contrast, partial nephrectomy resulted in a 10-year overall survival rate of 93%. The study's findings highlight the importance of considering long-term health consequences for patients...
A randomized controlled trial found that robotic teleconferencing resulted in similar patient outcomes and satisfaction as traditional bedside rounds. Patient satisfaction was equally high in both groups, with most rating audio and video quality as very good or excellent.
Researchers will focus on finding medical reasons for the constant urge to urinate, which affects one in six adults over 40 and can cause distress and anxiety. The team aims to develop better ways to identify, manage and treat this common condition.
A UTSouthwestern urologist has used botulinum toxin A (Botox) injections to treat involuntary bladder contractions in quadriplegic patients. The treatment has shown promising results, enabling patients to regain control of their bladders and improve their quality of life.
The AUA and EAU have released new guidelines for managing ureteral calculi, recommending updated treatment options such as ureteroscopy (URS) for all locations and sizes of stones. The guidelines also identify areas for future research to improve patient outcomes.
The American Urological Association has released new guidelines on managing non-muscle invasive bladder cancer, focusing on treatment outcomes and complications. The guidelines highlight the importance of accurate clinical staging and the need for further research to improve patient outcomes.
Men with bladder exstrophy report more robust sexual lives than women, with two-thirds of women experiencing moderate to severe dissatisfaction. Researchers aim to tweak surgical techniques to prevent sexual dysfunction in women.
Researchers found no real difference in quality-of-life reports between children with bladder abnormalities and healthy children, suggesting a need for fine-tuning existing quality-of-life screens. Children with chronic urological conditions scored higher than healthy children in certain areas, indicating potential adaptability.
A recent study of over 200 patients found that 88% were happy with their surgery at the first post-operative clinic visit. Despite complications, 76% were satisfied with the cosmetic result and 80% said the surgery met their expectations. Common issues included vaginal hair growth, prolapse, and necrosis.
A new study from the University of Michigan Comprehensive Cancer Center finds that cancer patients and their spouses experience similar physical and emotional quality of life. The study, which analyzed data from 263 men with prostate cancer and their spouses, found significant differences in quality of life based on the phase of illness.
Dr. John McConnell receives the 2007 Eugene Fuller Triennial Prostate Award for his innovative research studies on prostate enlargement and leadership in developing a multidisciplinary program at UT Southwestern. His research findings include combining alpha-blocking drugs to effectively treat benign prostatic hyperplasia.
A new study reveals that patients with localized prostate cancer are more likely to receive surgery if they see a urologist, while those who see a radiation oncologist and urologist tend to receive radiation therapy. The study suggests that men should seek a balanced perspective on treatment options from specialists.
Researchers delivered gene therapy containing nerve growth factors to rats with erectile dysfunction, resulting in significant recovery of intracavernous pressure and systemic arterial pressure. The study suggests a long-term treatment option for erectile dysfunction without chronic drug administration.
A research review found that men worry more about their penis size than women, with average-sized penises being just as desirable. Despite this, many men experience anxiety and small penis syndrome, which can be treated with conservative approaches such as therapy and education.
Researchers at the University of Pittsburgh School of Medicine have found that Botox injections can reduce prostate size and alleviate urinary tract symptoms in men with benign prostatic hyperplasia (BPH). Up to 73% of patients experienced improved quality of life and reduced symptoms for up to a year after treatment.
A minimally invasive device for stress urinary incontinence has been shown to be safe and effective in early clinical trials, demonstrating significant continence improvement in women. The device, ACT, eliminates the risk of overtreatment or undertreatment with adjustable balloons that can be adjusted post-operatively.
Studies suggest that phosphodiesterase inhibitors, commonly used for erectile dysfunction, can also alleviate lower urinary tract symptoms associated with benign prostatic hyperplasia. Researchers found improved scores on the International Index of Erectile Function and International Prostate Symptom Score, indicating potential benefit...
A study by NIH/NIDDK found that sling surgery was more effective in achieving dryness and quality of life for women with SUI, but had higher side effects. The procedure helped significantly more women achieve stress-specific success compared to the Burch technique.
Research reveals a connection between erectile dysfunction and various serious health conditions, including heart disease and metabolic syndrome. Chronic treatment with sildenafil has been shown to improve endothelial function and oxidative stress, suggesting potential benefits for cardiovascular indications.
Researchers have made significant breakthroughs in stem cell treatment options, including isolation of human spermatoogonial stem cells and use of autologous adipose-derived stem cells. Studies also show promise for engineered bladder tissue and muscle-derived cell injection in treating stress urinary incontinence.
Researchers have found that veterans exposed to Agent Orange have a 48% higher risk of prostate cancer recurrence following surgery compared to their unexposed peers. Black veterans with a history of exposure were also more likely to experience aggressive disease and rapid PSA level increases.
Researchers at NewYork-Presbyterian/Weill Cornell developed a simple and effective technique to reconstruct key anatomical structures that ensure continence. The procedure added only two to five minutes to standard robotic prostatectomy and achieved a 95% continence rate among patients 16 weeks after their surgeries.
Researchers at Johns Hopkins Medicine have developed a motor that can safely power remote-controlled robotic medical devices for cancer biopsies and therapies guided by magnetic resonance imaging. The motor, dubbed PneuStep, is made entirely out of plastics, ceramics, and rubber and is driven by light and air.
Urologists are urging transport companies and family doctors to develop strict guidelines for staff with kidney stones, as sudden attacks can cause debilitating pain and pose safety risks. The authors have devised their own guidelines, but stress the need for governing bodies to create formal ones.
A new study published in International Braz J Urol found that exposure to hot baths or hot tubs can lead to male infertility. However, the effects can be reversible if the practice is discontinued for at least three months. The study showed a significant increase in sperm motility among responders, with a mean increase of 491 percent a...
A recent study found that South Asian men experience more urinary problems than their white counterparts, including difficulties storing urine and urinating frequently. Despite this, they are less likely to seek medical attention or advice for these symptoms.
Researchers found that St. John's Wort increased bladder contraction intervals in rats with bladder inflammation, reducing bladder hyperactivity and associated pain. The study suggests that the herbal supplement may be a viable treatment option for women suffering from interstitial cystitis, affecting 700,000 Americans.
A recent study conducted by the UCLA School of Medicine found that testosterone replacement therapy does not negatively affect the prostate or its tissues in hypogonadal men. The six-month trial involved 41 men with low testosterone levels and showed no changes in prostate tissue, PSA, or DHT levels.
A new marijuana-derived drug, IP 751, has shown significant promise in suppressing bladder overactivity and alleviating painful symptoms in animal models of interstitial cystitis. Researchers at the University of Pittsburgh School of Medicine developed a liposome-based delivery system to overcome the hydrophobic properties of the drug.
Astellas Pharma US, Inc. has been recognized by the American Urological Association for its continued support of education and research initiatives in urology. The company's commitment to improving urologic care through innovative pharmaceutical products is being acknowledged by the AUA.
A study found that only three-quarters of men attended their eight-week sperm test, highlighting a significant issue with post-vasectomy follow-up care. Despite counselling, many patients failed to return for additional tests, leading to concerns about the true vasectomy failure rate.
A study found that 16% of adults in the US have overactive bladder (OAB), but only 1 in 25 suffers actually seeks medical attention. OAB is under-reported in research due to feelings of embarrassment and negative social stigma, leading to a large unmet medical need.
Men with high PSA levels prior to prostate removal surgery were significantly more likely to have advanced clinical stages of cancer and higher grade cancers in surgically removed tissue. Increasing PSA levels after surgery were also associated with increased risk of cancer recurrence.
A randomized, controlled trial found that comprehensive lifestyle changes, including a vegan diet and moderate exercise, can decrease PSA levels and inhibit prostate tumor growth in men with prostate cancer. The study suggests that making lifestyle changes may help prevent or reverse prostate cancer progression.
Researchers found that increased levels of O-GlcNAc, a simple sugar present in high blood sugar circumstances, interfere with the chain of events needed to achieve and maintain erection. This can lead to permanent penile impairment over time.
Researchers found improved patient outcomes in open nephron-sparing surgery (NSS) over time, attributed to increased surgeon experience and perioperative care. Open NSS showed benefits compared to laparoscopic NSS, particularly in complex tumor cases.
A recent study at Mayo Clinic found that transplanting kidneys with small stones does not significantly affect the kidney's function. The study followed 44 donor kidneys, of which 86% had stones smaller than 2mm, and reported a 97% graft survival rate after 26 months, comparable to national averages for living kidney donation.
The American Urological Association has awarded Novartis Pharmaceuticals its annual health science award in recognition of the company's support for the organization's educational, scientific, and research goals. The award acknowledges Novartis' contributions to promoting urologic care through continuing medical education.
A University of Pittsburgh study shows Botox injections significantly reduce irritative symptoms and improve quality of life index by 62.3% and 56.5% respectively. Patients experienced increased flow rate and decreased residual urine without significant side effects.
New studies release at the American Urological Association (AUA) show Enablex significantly reducing overactive bladder symptoms, including incontinence episodes and nocturia. Enablex improved efficacy parameters associated with OAB without CNS or CV safety concerns.
Researchers found that quality of life for men treated for prostate cancer continues to evolve long-term, with some experiencing improvements and others worsening. Sexual function remains a significant concern for survivors, with reported lower quality of life compared to non-cancerous individuals.