A smartphone-based device developed by Massachusetts General Hospital researchers uses hologram technology to collect detailed microscopic images for digital analysis of cancer cells and tissues. The D3 system can detect cancer proteins with high accuracy, categorizing biopsy samples as high-risk or low-risk in under an hour.
A team of researchers has demonstrated the advantages of the HOPE fixation strategy, which preserves tissue structure while allowing modern analysis techniques like proteomics and phospho-proteomics. This breakthrough enables personalized medicine and opens up new opportunities for disease research and therapy.
Researchers have developed a computational model called 'cell graphs' that links the structure of human tissue to its corresponding biological function. This new tool uses graph theory and can be used to determine whether a tissue sample is cancerous or not, eliminating differences of opinion between doctors.
Andreas Römpp and Sabine Guenther received the ABC Best Paper Award 2011 for their pioneering work on mass spectrometry imaging with high spatial resolution. Their method provided highly specific molecular information and excellent correlation with histological features.
The Monell Center has received a $2 million NIH Core grant to enhance technological and research services. The funding will support three Research Cores providing specialized expert services, equipment, and training in chemical senses research techniques.
An analysis of ancient Nubian-era mummies found that human alteration of the environment contributed to the spread of schistosomiasis, a water-borne parasitic disease infecting an estimated 200 million people today. The study suggests that ancient individuals were capable of altering their environment in ways that impacted their health.
Researchers at the University of Calgary developed a new digital tool using fractal dimension analysis to assess breast cancer tumours. The method provides an objective and reproducible measure of tissue abnormality and aggressiveness, promising more accurate risk assessment and therapeutic decisions.
A study found that pemetrexed-based treatment is more effective in patients with non-squamous histology than those with squamous histology, indicating improved survival benefits for some lung cancer patients.
Researchers at Georgia Tech's Center for Bio-Imaging Mass Spectrometry have developed new bio-imaging mass spectrometry techniques to analyze complex biological samples. These techniques allow for the visualization and localization of specific molecules in tissues, enabling a better understanding of biological systems.
A comprehensive study found that conventional prognostic factors do not adequately predict survival outcomes in Asian-American men with prostate cancer. Despite worse prognostic profiles, most Asian ethnic groups have better outcomes compared to white men.
Cedars-Sinai physicians advocate for pre-transplant liver biopsies in living donor liver transplants to detect chronic hepatitis, severe fat in the liver, and other complications that may go unnoticed through routine screenings. The analysis found that only 27% of donors had healthy livers without biopsy results.